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A randomized controlled trial of Promoting Physical Activity in Regional and Remote Cancer Survivors(PPARCS)

j.urnal of Sport and Health Science 2024年第1期13卷 81-89页

作者： Sarah j.Hardcastle Chloe Maxwell-Smith Vinicius Cavalheri Terry Boyle Marta Leyton Román Cameron Platell Michael Levitt Christobel Saunders Frank Sardelic Sophie Nightingale j.cob McCormick Craig Lynch paul A.Cohen Max Bulsara Dana Hince Sport and Physical Activity Research Centre Sheffield Hallam UniversitySheffieldS102BPUK Institute for Health Research The University of Notre DameFremantleWA 6959Australia Curtin School of Population Health Curtin UniversityPerthWA 6845Australia Curtin School of Allied Health Curtin UniversityPerthWA 6845Australia Allied Health South Metropolitan Health ServiceMurdochWA 6150Australia Australian Centre for Precision Health University of South AustraliaAdelaideSA 5001Australia Department of Didactics of Musical Plastic and Body ExpressionUniversity of ExtremaduraCaceres 10071Spain St.j.hn of God Subiaco Hospital PerthWA 6008Australia Department of Surgery University of MelbourneMelbourneVIC 3010Australia Tamara Private Hospital TamworthNSW 2340Australia Peter MacCallum Cancer Centre MelbourneVIC 3000Australia College of Health and Medicine Australian National UniversityCanberraACT 2600Australia Division of Obstetrics and Gynaecology Medical SchoolUniversity of Western AustraliaPerthWA 6009Australia

Background:Physical activity(PA)is important for cancer *** of remotely delivered interventions are needed to assist in reaching under-served non-metropolitan cancer *** obj.ctive of this study was to ascertain whether wearable technology,coupled with health coaching was effective in increasing PA in breast and colorectal cancer survivors living in regional and remote areas in ***:Cancer survivors from 5 states were randomized to intervention and control *** participants were given a Fitbit Charge 2TMand received up to 6 telephone health coaching *** participants received PA print *** assessments at baseline and 12 weeks measured moderate-to-vigorous PA(MVPA),light PA,and sedentary ***:Eighty-seven participants were recruited(age=63±11 years;74(85%)female).There was a significant net improvement in MVPA of 49.8 min/week,favoring the intervention group(95%confidence interval(95%CI):13.6-86.1,p=0.007).There was also a net increase in MVPA bouts of 39.5 min/week(95%CI:11.9-67.1,p=0.005),favoring the intervention *** groups improved light PA and sedentary behavior,but there were no between-group ***:This’s the first study to demonstrate that,when compared to standard practice(i.e.,PA education),a wearable technology intervention coupled with distance-based health coaching,improves MVPA in non-metropolitan cancer *** results display promise for the use of scalable interventions using smart wearable technology in conj.nction with phone-based health coaching to foster increased PA in geographically disadvantaged cancer survivors.

关键词： Behavior change Exercise Health disparities Oncology Wearable technology

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中国锂动力电池产业链污染调查评估及风险管控

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环境污染与防治 2024年第3期46卷 387-391,399页

作者：李媛时进钢陈楠张明博 paul P.j.Gaffney 生态环境部环境发展中心北京100029 中国科学院地理科学与资源研究所北京100101

在碳达峰、碳中和目标指引下,新能源汽车产业带动锂动力电池迅猛发展,锂动力电池全产业链包括上游锂资源开发利用与锂盐生产、中游锂动力电池原材料生产与锂动力电池制造、下游锂动力电池的回收与利用,其生产过程均对生态环境产生不同... 详细信息

在碳达峰、碳中和目标指引下,新能源汽车产业带动锂动力电池迅猛发展,锂动力电池全产业链包括上游锂资源开发利用与锂盐生产、中游锂动力电池原材料生产与锂动力电池制造、下游锂动力电池的回收与利用,其生产过程均对生态环境产生不同程度的影响。基于全国环境影响评价管理信息平台相关数据及产业链产排污特征分析,研究指出中国锂动力电池产业发展面临的环境风险,并提出针对性的建议。结果表明,上游锂资源扩产面临较大的生态环境风险,锂盐生产或影响区域环境空气质量;中游锂动力电池生产过程涉及多种重金属与有机物,存在环境风险;下游回收利用现状不容乐观;建议从环境准入、排污许可、企业环境主体责任等方面入手,加强全产业链的环境风险管控。

关键词：锂动力电池全产业链产污特征生态环境风险环境管理

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Causes of Cretaceous subduction termination below South China and Borneo:Was the Proto-South China Sea underlain by an oceanic plateau?

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Geoscience Frontiers 2024年第2期15卷 100-124页

作者： Suzanna H.A.van de Lagemaat Licheng Cao j.naidi Asis Eldert L.Advokaat paul R.D.Mason Mark j.Dekkers Douwe j.j.van Hinsbergen Department of Earth Sciences Utrecht UniversityUtrechtthe Netherlands College of Marine Science and Technology China University of GeosciencesWuhanChina Faculty of Science and Natural Resources Universiti Malaysia SabahKota KinabaluMalaysia

The South China,Indochina,and Borneo margins surrounding the South China Sea contain long-lived arcs that became inactive at approximately 85 Ma,even though an embayment of oceanic crust(the‘Proto-South China Sea’)remained in the intervening *** oceanic crust eventually subducted in the Cenozoic below Borneo and the Cagayan arc,while the modern South China Sea opened in its *** investigate the enigmatic cessation of Mesozoic subduction below South China and Borneo,we studied a fragment of oceanic crust and overlying trench-fill sediments that accreted to NW Borneo during the final stages of Paleo-Pacific *** on radiolarian biostratigraphy of cherts overlying the pillow basalts and detrital zircon geochronology of the trench-fill,we constrained the minimum age of the oceanic crust during accretion to 40 *** shows that subduction cessation was not related to ridge *** analysis of pillow basalts revealed an enriched mid-ocean ridge basalt signature comparable to oceanic *** paleomagnetism,we show that this fragment of oceanic crust was not part of the Izanagi Plate but was part of a plate(the‘Pontus’Plate)separated from the Izanagi Plate by a subduction *** on the minimum 40 Ma age of the oceanic crust and its geochemistry,we suggest that Mesozoic subduction below South China and Borneo stopped when an oceanic plateau entered the trench,while the eastern plate margin with the Izanagi Plate remained *** show how our findings offer opportunities to restore plate configurations of the Panthalassa-Tethys j.nction region.

关键词： Proto-South China Sea Paleomagnetism Geochemistry Borneo Paleo-Pacific Izanagi Plate

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Advances in newly developing therapy for chronic hepatitis C virus infection

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Frontiers of Medicine 2014年第2期8卷 166-174页

作者： paul j. Pockros Division of Gastro/Hepatology Scripps Clinic 10666 N Torrey Pines Road N203 La Jolla CA 92067 USA

Chronic hepatitis C virus （HCV） infection afflicts a reported 170 million people worldwide and is often complicated by cirrhosis and hepatocellular carcinoma. Morbidity and mortality are decreased with the successful treatment of chronic HCV infection. Increased understanding of the HCV has allowed further development of new direct-acting antiviral （DAA） agents against the HCV and has also allowed the development of IFN-free oral treatment regimens. In late 2013 the first nucleotide polymerase inhibitor regimen with RBV alone for genotypes 2/3 and in combination with a 12-week regimen of PEG-IFN ＋ RBV for genotypes 1, 4 was approved for use in the US. A number of promising new DAA regimens which are IFN-free are in phase 3 development and the first will likely be approved for use in the US in 2014. The currently approved regimens are discussed in detail and currently available data on future regimens are reviewed herein.

关键词： direct-acting antiviral (DAA) nucleotide polymerase inhibitors protease inhibitors

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华尔街察觉到“野蛮人”归来

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商业周刊（中文版） 2024年第13期 24-25页

作者： paul j.Davies 程玺(译) 不详

经历多次误判后,摩根士丹利、高盛等机构的银行家们相信,期待已久的私募交易和投行费用的复苏终于临近.“野蛮人”杀回来了。摩根士丹利(Morgan Stanley)和高盛集团(Goldman Sachs Group Inc.)相信,他们最重要的客户在长期观望之后,即... 详细信息

经历多次误判后,摩根士丹利、高盛等机构的银行家们相信,期待已久的私募交易和投行费用的复苏终于临近.“野蛮人”杀回来了。摩根士丹利(Morgan Stanley)和高盛集团(Goldman Sachs Group Inc.)相信,他们最重要的客户在长期观望之后,即将卷土重来,并有望推动期待已久的投资银行费用的复苏。

关键词：摩根士丹利银行费用高盛集团私募投行费用银行家华尔街复苏

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A system-on-chip microwave photonic processor solves dynamic RF interference in real time with picosecond latency

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Light(Science & Applications) 2024年第1期13卷 91-102页

作者： Weipeng Zhang j.shua C.Lederman Thomas Ferreira de Lima j.awei Zhang Simon Bilodeau Leila Hudson Alexander Tait Bhavin j.Shastri paul R.Prucnal Department of Electrical and Computer Engineering Princeton UniversityPrinceton08544NJUSA NEC Laboratories America Princeton08540NJUSA Department of Electrical and Computer Engineering Queen’s UniversityKingstonK7L 3N6OntarioCanada Department of Physics Engineering Physics and AstronomyQueen’s UniversityKingstonK7L 3N6OntarioCanada

Radio-frequency interference is a growing concern as wireless technology advances,with potentially life-threatening consequences like interference between radar altimeters and 5 G cellular *** transceivers mix signals with varying ratios over time,posing challenges for conventional digital signal processing(DSP)due to its high *** challenges will worsen as future wireless technologies adopt higher carrier frequencies and data ***,conventional DSPs,already on the brink of their clock frequency limit,are expected to offer only marginal speed *** paper introduces a photonic processor to address dynamic interference through blind source separation(BSS).Our system-on-chip processor employs a fully integrated photonic signal pathway in the analogue domain,enabling rapid demixing of received mixtures and recovering the signal-of-interest in under 15 *** reduction in latency surpasses electronic counterparts by more than three orders of *** complement the photonic processor,electronic peripherals based on field-programmable gate array(FPGA)assess the effectiveness of demixing and continuously update demixing weights at a rate of up to 305 *** compact setup features precise dithering weight control,impedance-controlled circuit board and optical fibre packaging,suitable for handheld and mobile *** experimentally demonstrate the processor’s ability to suppress transmission errors and maintain signal-to-noise ratios in two scenarios,radar altimeters and mobile *** work pioneers the real-time adaptability of integrated silicon photonics,enabling online learning and weight adj.stments,and showcasing practical operational applications for photonic processing.

关键词： processor mixing dynamic

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做市商巨头不可能抢走华尔街的全部收入

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商业周刊（中文版） 2024年第14期 26-27页

作者： paul j.Davie 逸思(译) 不详

两家电子做市商凭借强于竞争对手的灵活性抢占了市场份额,但其商业模式存在局限,简街资本(j.ne Street Group LLC)和城堡证券(Citadel Securities)在蒸蒸日上。据彭博新闻社报道,上半年,这两家以电子做市业务为主的公司收入较上年同期... 详细信息

两家电子做市商凭借强于竞争对手的灵活性抢占了市场份额,但其商业模式存在局限,简街资本(j.ne Street Group LLC)和城堡证券(Citadel Securities)在蒸蒸日上。据彭博新闻社报道,上半年,这两家以电子做市业务为主的公司收入较上年同期增长约80%。这足以让华尔街传统业务公司的高管羡慕——但两家后起之秀并不会完全抢走传统业务公司的午餐。

关键词：做市商彭博新闻社商业模式市场份额华尔街高管证券竞争对手

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Molecular Oxygen Abundance in Galactic Massive Star Formation Regions Based on SWAS Observations

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Research in Astronomy and Astrophysics 2024年第9期24卷 85-100页

作者： Bing-Ru Wang Di Li paul F.Goldsmith j.ngwen Wu Chao-Wei Tsai Donghui Quan Xia Zhang j.nzhi Wang Gary j.Melnick j.n-Zeng Li Gary A.Fuller j.nj.n Xie National Astronomical Observatories Chinese Academy of Sciences University of Chinese Academy of Sciences Tsinghua University Research Center for Astronomical Computing Zhejiang Laboratory j.t Propulsion Laboratory California Institute of Technology Institute for Frontiers in Astronomy and Astrophysics Beijing Normal University Xinj.ang Astronomical Observatory Chinese Academy of Sciences Guangxi Key Laboratory for Relativistic Astrophysics School of Physical Science and TechnologyGuangxi University Center for Astrophysics Harvard&Smithsonian60 Garden Street j.drell Bank Center for Astrophysics Department of Physics&AstronomyUniversity of Manchester I.Physikalisches Institut University of Cologne

Molecular oxygen abundance is a key parameter in understanding the chemical network of the interstellar *** estimate the molecular oxygen column density and abundance for a sample of Galactic massive star formation regions based on observations from the Submillimiter Wave Astronomy Satellite （SWAS） *** obtained an averaged O2spectrum based on this sample using the （SWAS） survey data （O2,487.249 GHz,N=3–1,j.3–2）.No emission or absorption feature is seen around the supposed central velocity with a total integration time of ttotal=8.67×10～3hr and an rms noise per channel of 1.45 m *** a kinetic temperature Tkin=30 K,we derive the 3σupper limit of the O2column density to be 3.3×1015cm-2,close to the lowest values reported in Galactic massive star formation regions in previous *** corresponding O2abundance upper limit is6.7×10-8,lower than all previous results based on SWAS observations and is close to the lowest reported value in massive star formation *** a galactic scale,our statistical results confirm a generally low O2abundance for Galactic massive star formation *** abundance is also lower than results reported in extragalactic sources.

关键词： ISM: molecules galaxies: abundances ISM: lines and bands Galaxy: abundances HERSCHEL HIFI OBSERVATIONS CARBON-MONOXIDE ABUNDANCE WAVE-ASTRONOMY-SATELLITE ODIN OBSERVATIONS THERMAL BALANCE UPPER LIMITS CLOUD CORES INTERSTELLAR O-2 SEARCH

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Blood metal concentrations and cardiac structure and function in total j.int arthroplasty patients

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World j.urnal of Orthopedics 2024年第8期15卷 773-782页

作者： Peter C Brennan Stephanie M Peterson Thomas j.O'Byrne Mariana L Laporta Cody C Wyles paul j.j.nnetto Garvan C Kane Maria Vassilaki Hilal Maradit Kremers Department of Orthopedic Surgery Mayo ClinicRochesterMN 55905United States Department of Quantitative Health Sciences Mayo ClinicRochesterMN 55905United States Department of Anesthesiology and Perioperative Medicine Mayo ClinicRochesterMN 55905United States Department of Laboratory Medicine and Pathology Mayo ClinicRochesterMN 55905United States Department of Cardiovascular Diseases Mayo ClinicRochesterMN 55905United States

BACKGROUND There is concern regarding potential long-term cardiotoxicity with systemic distribution of metals in total j.int arthroplasty(Tj.)*** To determine the association of commonly used implant metals with echocardiographic measures in Tj. *** The study comprised 110 Tj. patients who had a recent history of high chromium,cobalt or titanium *** underwent two-dimensional,three-dimensional,Doppler and speckle-strain transthoracic echocardiography and a blood draw to measure metal *** and sex-adj.sted linear and logistic regression models were used to examine the association of metal concentrations(exposure)with echocardiographic measures(outcome).RESULTS Higher cobalt concentrations were associated with increased left ventricular end-diastolic volume(estimate 5.09;95%CI:0.02-10.17)as well as left atrial and right ventricular dilation,particularly in men but no changes in cardiac *** titanium concentrations were associated with a reduction in left ventricle global longitudinal strain(estimate 0.38;95%CI:0.70 to 0.06)and cardiac index(estimate 0.08;95%CI,-0.15 to-0.01).CONCLUSION Elevated cobalt and titanium concentrations may be associated with structural and functional cardiac changes in some *** studies are warranted to better understand the systemic effects of metals in Tj. patients.

关键词： Total j.int arthroplasty Metal-on-metal Cardiotoxicity Heart failure Echocardiography Cobalt

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Three-dimensional simulation of liquid inj.ction,film formation and transport,in fluidized beds

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Particuology 2009年第5期7卷 337-346页

作者： paul Zhao Peter j. O'Rourke Dale Snider CPFD Software LLCAlbuquerqueNM 87111USA CFD d'OR Software and Consulting LLCLos AlamosNM 87544USA

Liquid inj.ction, and film formation and transport in dense-phase gas-solids fluidized beds are numerically simulated in three dimensions using a collisional exchange model that is based on the mechanism that collisions cause transfer of liquid mass, momentum, and energy between particles. In the model, each of the particles is represented by a solid core and a liquid film surrounding the core. The model is incorporated in the framework of the commercial code Barracuda developed by CPFD Software. The commercial software is an advanced CFD-based computational tool where the particles are treated as discrete entities, calculated by the MP-PIC method, and tracked using the Lagrangian method. Details of the collisional liquid transfer model have been previously presented in O＇Rourke, Zhao, and Snider （2009）; this paper presents new capabilities and proof-testing of the collision model and a new method to better quantify the penetration length. Example calculations of a fluidized bed without liquid inj.ction show the expected effect of collisions on the reduction of granular temperature （fluctuational kinetic energy） of the bed. When applied to liquid inj.ction into a dense-phase fluidized bed under different conditions, the model predicts liquid penetration lengths comparable to the experiments. In addition, the simulation reveals for the first time the dynamic mixing of the liquid droplets with the bed particles and the transient distribution of the droplets inside the bed.

关键词： MP-PIC Liquid inj.ction Fluidized bed Particle collisions CPFD j.t penetration

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