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Protective effects of trilinolein extracted from Panax notoginseng against cardiovascular disease

Acta Pharmacologica Sinica 2002年第12期23卷 104-109页

作者： paul chan,g neil thomas,brian tomlinson Division of Cardiovascular Medicine Taipei Medical College Affiliated Taipei Wan Fang Hospital Taipei China Department of Medicine and Therapeutics The Chinese University of Hong Kong Prince of Wales Hospital Shatin NT Hong Kong SAR China Department of Medicine and Therapeutics The Chinese University of Hong Kong Prince of Wales Hospital Shatin NT Hong Kong SAR China

Trilinolein is a triacylglycerol purified from a commonly used traditional Chinese medicine Panax notoginseng. Trilinolein has been reported to provide a number of beneficial effects including reducing thrombogenicity and arrhythmias and increasing erythrocyte deformability. Additionally, trilinolein has been reported to be an antioxidant, which can counteract free radical damage associated with atherogenesis, and myocardial damage seen with is-chaemia and reperfusion. These pharmacologic effects may explain the perceived benefits derived from treating circulatory disorders with the herb over the centuries.

关键词： antioxidants cardiovascular system Chinese traditional medicine trilinolein Panax notoginseng

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Relationship between obesity and cardiovascular risk factors in elderly Chinese subjects

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Chinese Medical Journal 2002年第6期115卷 897-899,155页

作者： g neil thomas 赵海潞马艳青 Wilson YS LEUNg Juliana CN chan brian tomlinson Julian AJH CRITCHLEY 梁润成陈重娥汤宁信郭志良香港中文大学医学院内科药物与治疗系临床药理学部

OBJECTIVE: To investigate the relative effects of degree and distribution of body fat with several cardiovascular disease (CVD) risk factors in elderly Chinese subjects. METHODS: One hundred and thirty-five elderly Chinese individuals (age range, 60-65 y) without any history of significant renal, hepatic or cardiac disease were recruited. Seated blood pressure, anthropometric and fasting plasma biochemical parameters were measured. Student's t-test was used to compare the differences in biochemical and anthropometric markers between cohorts. RESULTS: Males were heavier (64.6 +/- 8.6, 57.2 +/- 8.2kg, P

关键词： Adult Aged Body Mass Index Cardiovascular Diseases Female Humans Male Middle Aged Obesity Research Support, Non-U.S. gov't Risk Factors

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