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Impact of patch size on woody tree species richness and abundance in a tropical montane evergreen forest patches of south India

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journal of Forestry Research 2018年第6期29卷 1675-1687页

作者： Dharmalingam Mohandass mason j.Campbell Priya Davidar Root and Soil Biology Laboratory Department of BotanyBharathiar UniversityCoimbatoreTaminadu 641046India Centre for Tropical Environmental and Sustainability Science(T.E.S.S.) College of Science and EngineeringJames Cook UniversityCairnsQLD 4870Australia Department of Ecology and Environmental Sciences Pondicherry UniversityKalapetPondicherry 605014India

We examined the effects of forest patch size on woody tree species richness and abundance in tropical montane evergreen forest patches of the Nilgiri region,south India. We sampled woody trees(>1 cm dbh) from 21 forest patches in the upper Nilgiri hills(> 2000 m elevation) and recorded a total of 35,146 individuals of 61 species, 45 genera and 30 families. Species richness and abundance of sapling/shrubs(≥ 1 to jor role in determining the inherent plant community and thus the subsequent ecological processes of forest patches, including their responses to increasing patch area.

关键词： Dispersal mode Forest fragments Shade-tolerance Species–area relationships Western Ghats

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Causes of Cretaceous subduction termination below South China and Borneo:Was the Proto-South China Sea underlain by an oceanic plateau?

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Geoscience Frontiers 2024年第2期15卷 100-124页

作者： Suzanna H.A.van de Lagemaat Licheng Cao junaidi Asis Eldert L.Advokaat paul R.D.mason Mark j.Dekkers Douwe j.j.van Hinsbergen Department of Earth Sciences Utrecht UniversityUtrechtthe Netherlands College of Marine Science and Technology China University of GeosciencesWuhanChina Faculty of Science and Natural Resources Universiti Malaysia SabahKota KinabaluMalaysia

The South China,Indochina,and Borneo margins surrounding the South China Sea contain long-lived arcs that became inactive at approximately 85 Ma,even though an embayment of oceanic crust(the‘Proto-South China Sea’)remained in the intervening *** oceanic crust eventually subducted in the Cenozoic below Borneo and the Cagayan arc,while the modern South China Sea opened in its *** investigate the enigmatic cessation of Mesozoic subduction below South China and Borneo,we studied a fragment of oceanic crust and overlying trench-fill sediments that accreted to NW Borneo during the final stages of Paleo-Pacific *** on radiolarian biostratigraphy of cherts overlying the pillow basalts and detrital zircon geochronology of the trench-fill,we constrained the minimum age of the oceanic crust during accretion to 40 *** shows that subduction cessation was not related to ridge *** analysis of pillow basalts revealed an enriched mid-ocean ridge basalt signature comparable to oceanic *** paleomagnetism,we show that this fragment of oceanic crust was not part of the Izanagi Plate but was part of a plate(the‘Pontus’Plate)separated from the Izanagi Plate by a subduction *** on the minimum 40 Ma age of the oceanic crust and its geochemistry,we suggest that Mesozoic subduction below South China and Borneo stopped when an oceanic plateau entered the trench,while the eastern plate margin with the Izanagi Plate remained *** show how our findings offer opportunities to restore plate configurations of the Panthalassa-Tethys junction region.

关键词： Proto-South China Sea Paleomagnetism Geochemistry Borneo Paleo-Pacific Izanagi Plate

A functional tacrolimus-releasing nerve wrap for enhancing nerve regeneration following surgical nerve repair

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Neural Regeneration Research 2025年第1期20卷 291-304页

作者： Simeon C.Daeschler Katelyn j.W.So Konstantin Feinberg Marina Manoraj jenny Cheung jennifer Zhang Kaveh Mirmoeini jpaul Santerre Tessa Gordon Gregory HBorschel SickKids Research Institute Neuroscience and Mental Health ProgramTorontoONCanada Institute of Biomaterials and Biomedical Engineering University of TorontoTorontoONCanada Indiana University School of Medicine IndianapolisINUSA Division of Plastic and Reconstructive Surgery the Hospital for Sick ChildrenTorontoONCanada Translational Biology and Engineering Program Ted Rogers Centre for Heart ResearchInstitute of Biomedical EngineeringFaculty of DentistryUniversity of TorontoTorontoONCanada

Axonal regeneration following surgical nerve repair is slow and often incomplete,resulting in poor functional recovery which sometimes contributes to lifelong ***,there are no FDA-approved therapies available to promote nerve *** accelerates axonal regeneration,but systemic side effects presently outweigh its potential benefits for peripheral nerve *** authors describe herein a biodegradable polyurethane-based drug delivery system for the sustained local release of tacrolimus at the nerve repair site,with suitable properties for scalable production and clinical application,aiming to promote nerve regeneration and functional recovery with minimal systemic drug *** is encapsulated into co-axially electrospun polycarbonate-urethane nanofibers to generate an implantable nerve wrap that releases therapeutic doses of bioactive tacrolimus over 31 *** and drug loading are adjustable for applications in small and large caliber nerves,and the wrap degrades within 120 days into biocompatible *** released from the nerve wrap promotes axon elongation in vitro and accelerates nerve regeneration and functional recovery in preclinical nerve repair models while off-target systemic drug exposure is reduced by 80%compared with systemic *** its surgical suitability and preclinical efficacy and safety,this system may provide a readily translatable approach to support axonal regeneration and recovery in patients undergoing nerve surgery.

关键词： biodegradable local drug delivery nerve injury nerve regeneration nerve wrap tacrolimus

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Advances in newly developing therapy for chronic hepatitis C virus infection

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Frontiers of Medicine 2014年第2期8卷 166-174页

作者： paul j. Pockros Division of Gastro/Hepatology Scripps Clinic 10666 N Torrey Pines Road N203 La Jolla CA 92067 USA

Chronic hepatitis C virus （HCV） infection afflicts a reported 170 million people worldwide and is often complicated by cirrhosis and hepatocellular carcinoma. Morbidity and mortality are decreased with the successful treatment of chronic HCV infection. Increased understanding of the HCV has allowed further development of new direct-acting antiviral （DAA） agents against the HCV and has also allowed the development of IFN-free oral treatment regimens. In late 2013 the first nucleotide polymerase inhibitor regimen with RBV alone for genotypes 2/3 and in combination with a 12-week regimen of PEG-IFN ＋ RBV for genotypes 1, 4 was approved for use in the US. A number of promising new DAA regimens which are IFN-free are in phase 3 development and the first will likely be approved for use in the US in 2014. The currently approved regimens are discussed in detail and currently available data on future regimens are reviewed herein.

关键词： direct-acting antiviral (DAA) nucleotide polymerase inhibitors protease inhibitors

The Bemisia tabaci Species Complex:Questions to Guide Future Research

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journal of Integrative Agriculture 2012年第2期11卷 187-196页

作者： paul j De Barro CSIRO Ecosystem Sciences Brisbane QLD 4001Australia

Since 2007 we have began to consider the relationships between the different members of the Bemisia tabaci species complex in a more structured and systematic *** of these relationships has been infered from considerations of a portion of the mitochondrial cytochrome oxidase one（mtCOI）*** this is a quite limited approach which would benefit from the consideration of a much greater diversity of genetic material,it is the only publically available data that spans the diversity of the species *** the limitations,the phylogenetic reconstruction that can be derived from this data is useful and can be used as a basis to frame questions and construct testable hypotheses that will form the basis for future *** study uses the largest available mtCOI dataset,consisting of 383 unique mtCOI haplotypes that spans the full diversity of the *** species complex as we currently know it,to make a range of observations which are then used to develop questions as guide for future research.

关键词： mitochondrial cytochrome oxidase one phylogenetic analysis

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Predicting User Satisfaction of Non-volitional Enterprise Systems: An Example From Telecomunications

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Chinese Business Review 2019年第1期18卷 1-13页

作者： paul A. j. mason Akaret Tangsuwan Shinawatra University Pathum Thani Thailand Convergsys Bangkok Thailand

The rapid pace of technological change has seen information and communication technologies become the digital backbone of developed nations’ economies and a pre-requisite for global trade. Some enterprise systems are however more than mere facilitators, they provide the bedrock without which organizations could not function;we term these mandatory systems “non-volitional”(NVS). With hyper-growth in demand for connectivity, telecommunications are typical of sectors where NVS shape the fiercely competitive landscape. Among them, Billing & Revenue Management Systems (BRMS) are a form of credit, providers deliver a service and subscribers later pay for that service. As such, they are “business critical”, meaning failures may affect an organization’s ability to conduct its core business. Failures also impact user satisfaction, a key measure of information systems success. However, relatively few studies empirically test this notion;fewer still evaluate it at organizational (rather than individual) level, while there is a dearth of literature investigating non-volitional systems and, to the best of our knowledge, none whatsoever consider ways of predicting user satisfaction for BRMS. According to a renowned and widely cited conceptual model, user satisfaction is influenced by information, system, and service quality respectively. To test this theory for telecoms BRMS, we applied structural equation modelling to investigate which of these dimensions has the most effect. The results indicate that information quality, system quality, service quality, and user satisfaction are all valid measures of BRMS success. Hypothesized relationships between the four success dimensions were significantly substantiated. The study also identified five measures of information quality, four measures of system quality, four measures of service quality, and four measures of user satisfaction. Once the proposed model had been successfully validated, we tested the level of significance among use

关键词： Billing & Revenue Management Systems success non-volitional systems organizational impact user satisfaction measures information quality system quality service quality

The rise of 3D cellular spheroids: efficient culture via upward growth from a superamphiphobic surface

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National Science Review 2019年第6期6卷 1068-1069页

作者： paul j.Dyson Institut des Sciences et Ingénierie Chimiques Ecole Polytechnique Fédérale de Lausanne

Cell culture assays are extensively used in drug discovery and development programs, biomedical research, and in many others areas of science. Currently,2D monolayer cellular assays serve as the gold standard. However, while they provide seemingly indispensable information on drug activity, it is estimated that of the putative drug candidates selected

关键词： The rise of 3D cellular spheroids efficient culture via upward growth from a superamphiphobic surface

Reconstituting mammalian spermatogenesis using stem ：ells

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Asian journal of Andrology 2011年第6期13卷 795-796页

作者： paul j Turek The Turek Clinic San Francisco CA 94133 USA

While stock markets and economies are smoldering all over the world, stem cell science is on fire. The promise of curing many untreatable forms of human male infertility is now one small step closer based on a recent paper in Cell. In this work, scientists from Kyoto University in japan created mature, fertile sperm from embryonic and induced pluripotent stem cells by grabbing the primitive germ cells called primordial germ cells just as they were being made from their pluripotent precursors in vitro and transplanting them back into genetically sterile mice.

关键词： Biological sciences Cell biology Microbiology

Hyperbolic Divergence Cleaning in Lattice Boltzmann Magnetohydrodynamics

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Communications in Computational Physics 2023年第1期33卷 245-272页

作者： paul j.Dellar OCIAM Mathematical InstituteUniversity of OxfordRadcliffe Observatory QuarterOxford OX26GGUK

Magnetohydrodynamics couples the Navier-Stokes and Maxwell’s equations to describe the flow of electrically conducting fluids in magnetic ***’s equations require the divergence of the magnetic field to vanish,but this condition is typically not preserved exactly by numerical *** can develop artifacts because structural properties of the magnetohydrodynamic equations then fail to *** with hyperbolic divergence cleaning permits a nonzero divergence that evolves under a telegraph equation,designed to both damp the divergence,and propagate it away from any sources,such as poorly resolved regions with large spatial gradients,without significantly increasing the computational *** show that existing lattice Boltzmann algorithms for magnetohydrodynamics already incorporate hyperbolic divergence cleaning,though they typically use parameter values for which it reduces to parabolic divergence cleaning under a slowly-varying *** recover hyperbolic divergence cleaning by adjusting the relaxation rate for the trace of the tensor that represents the electric field,and absorb the contribution from the symmetric-traceless part of this tensor using a change of *** experiments confirm that the qualitative behaviour changes from parabolic to hyperbolic when the relaxation time for the trace of the electric field tensor is increased.

关键词： Magnetohydrodynamics divergence cleaning telegraph equations matrix collision operators linear viscoelasticity