检索结果-南通市图书馆

Gut steriliza.ion in experimenta. colitis leukocyte media.ed colon injury, a.d effects on a.giogenesis/lympha.giogenesis

引用

Open Journa. of Ga.troenterology 2013年第1期3卷 12-24页

作者： Mihir Pa.el Justin Olinde a.lison Ta.um Cha.ta.ya.V. Ga.ta.Wa.ter E. Cromer a.kur R. Sheth Merilyn H. Jennings J. Micha.l Ma.his Tra.i Testerma. paul a. jordan Kenneth Ma.a. Christopher P. Moncea.x J. Steven a.exa.der Depa.tment of Cellula. Biology a.d a.a.omy LSU Health Shreveport Shreveport USA Depa.tment of Ga.troenterology a.d Hepa.ology LSU Health Shreveport Shreveport USA Depa.tment of Microbiology a.d Immunology LSU Health Shreveport Shreveport USA Depa.tment of Molecula. a.d Cellula. Physiology LSU Health Shreveport Shreveport USA

Ina.propria.e responses to norma. commensa. ba.teria.trigger immune a.tiva.ion in both infla.ma.ory bowel disea.e a.d experimenta. colitis. How gut flora.contribute to the pa.hogenesis of infla.ma.ory bowel disea.e is unclea., but ma. involve entra.ment of leukocytes a.d remodeling of the va.cula. system. Here we eva.ua.ed how the progression a.d tissue remodeling in experimenta. colitis differ in a.germ- free model of mouse colitis. Four trea.ment groups were used: control, a.tibiotic-trea.ed (a.X), dextra. sulfa.e colitis (DSS) a.d DSS pre- a.d co-trea.ed with a.tibiotics (DSS + a.X). In da.s 0 - 3 of the study, germ-free mice received a.tibiotics (va.comycin, neomycin, a.d metronida.ole). During the next 11 da.s, a.tibiotics were continued a.d DSS (3%) a.ded to “colitis” groups. Disea.e a.tivity, weight, stool form a.d blood were monitored da.ly. Mice were sa.rificed a.d tissue sa.ples ha.vested. Histopa.hologica. scores in controls (0.00) a.d in a.X (1.0+/–0.81) were significa.tly (p –0). Extents of injury, infla.ma.ion a.d crypt da.a.e were a.l improved in DSS + a.X. The Disea.e a.tivity Index score (da. 11) wa. significa.tly worse in the DSS group compa.ed to the DSS + a.X group. Stool blood a.d form scores were a.so significa.tly improved a.ong these groups. Importa.tly, myeloper- oxida.e wa. significa.tly reduced in DSS + a.X, indica.ing tha. neutrophil infiltra.ion wa. blocked. Colitis wa. a.socia.ed with a. increa.e in blood a.d lympha.ic vessels;both of these events were a.so significa.tly reduced by gut steriliza.ion. Our experiment shows tha. clinica. a.d histopa.hologica. severity of colitis wa. significa.tly worse in the DSS colitis group compa.ed to the DSS + a.X group, supporting the hypothesis tha. development of IBD is likely to be less severe with a.propria.e a.tibiotic trea.ment. In pa.ticula., gut steriliza.ion effectively reduces leuko- cyte-dependent (PMN) injury to improve outcomes a.d ma. be a. importa.t ta.get for thera.y.

关键词： Crohn’s Disea.e a.tibiotics Myeloperoxida.e Lympha.ics a.giogenesis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Multiplexed cytokine detection on pla.monic gold substra.es with enha.ced nea.-infra.ed fluorescence

引用

Na.o Resea.ch 2013年第2期6卷 113-120页

作者： Bo Zha.g jordan Price Guosong Hong Scott M. Ta.a.ma. Ha.lia.g Wa.g Justin a. Ja.rell Ju Feng paul J. Utz Hongjie Da. Depa.tment of Chemistry Stanford University Stanford California USA Depa.tment of Medicine Division of Immunology and Rheumatology Stanford University School of Medicine Stanford California USA Institute for Immunity Transplantation and Infection Stanford University School of Medicine Stanford California USA

Protein microa.ra.s ba.ed on fluorescence detection ha.e been widely utilized for high-throughput functiona. proteomic a.a.ysis. However, a.dra.ba.k of such a.sa.s ha. been low sensitivity a.d na.row dyna.ic ra.ge, limiting their ca.a.ilities, especia.ly for detecting low a.unda.ce biologica. molecules such a. cytokines in huma. sa.ples. Here, we present fluorescence-enha.cing microa.ra.s on pla.monic gold films for multiplexed cytokine detection with up to three orders of ma.nitude higher sensitivity tha. on conventiona. nitrocellulose a.d gla.s substra.es. Cytokine detection on the gold pla.monic substra.e is a.out one to two orders of ma.nitude more sensitive tha. enzyme-linked immunosorbent a.sa. （ELISa. a.d ca. be multiplexed. a.pa.el of six cytokines （Va.cula. endothelia. growth fa.tor （VEGF）, Interleukin 1β （IL-1β）, Interleukin 4 （IL-4）, Interleukin 6 （IL-6）, Interferon γ （IFN-γ）, a.d Tumor necrosis fa.tor （TNF）） were detected in the culture media.of ca.cer cells. This work esta.lishes a.new method of high throughput multiplexed cytokine detection with higher sensitivity a.d dyna.ic ra.ge tha. ELISa.

关键词： microa.ra. cytokine pla.monic multiplex nea. infra.ed fluorescence

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Non-celia. gluten sensitivity: a.l whea. a.ta.k is not celia.

引用

World Journa. of Ga.troenterology 2017年第40期23卷 7201-7210页

作者： Sa.uel O Igbinedion Juna.d a.sa.i a.ush Va.ika.a. Felicity N Ga.ins paul jordan Moheb Boktor Jona.ha. S a.exa.der Depa.tment of Interna. Medicine Louisiana State University Health Sciences Center Depa.tment of Molecula. a.d Cellula. Physiology Louisiana State University School of Medicine Depa.tment of Ga.troenterology a.d Hepa.ology Louisiana State University Health Sciences Center

Currently,1% of the United Sta.es popula.ion holds a.dia.nosis for celia. disea.e(CD),however,a.more recently recognized a.d possibly rela.ed condition,"non-celia. gluten sensitivity"(NCGS)ha. been suggested to a.fect up to 6%of the United Sta.es *** relia.le clinica. tests for CD exist,dia.nosing individua.s a.fected by NCGS is still complica.ed by the la.k of relia.le bioma.kers a.d relia.ce upon a.broa. set of intestina. a.d extra.intestina. symptoms possibly provoked by *** ha. been proposed to exhibit a. inna.e immune response a.tiva.ed by gluten a.d severa. other whea. *** present,a. enormous food industry ha. developed to supply gluten-free products(GFP)with GFP sa.es in 2014 a.proa.hing$1 billion,with estima.ions projecting sa.es to rea.h$2 billion in the yea. *** enormous dema.d for GFP a.so reflects a.popula. misconception a.ong consumers tha. gluten a.oida.ce is pa.t of a.hea.thy lifestyle *** of NCGS a.d other gluten rela.ed disorders(e.g.,irrita.le bowel syndrome)ca.l for a.review of current distinctive dia.nostic criteria.tha. distinguish ea.h,a.d identifica.ion of bioma.kers selective or specific for *** a.m of this pa.er is to review our current understa.ding of NCGS,highlighting the rema.ning cha.lenges a.d questions which ma. improve its dia.nosis a.d trea.ment.

关键词： Non-celia. gluten sensitivity Celia. disea.e Gluten Whea. Gluten rela.ed disorder Gluten free diet

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Vibra.ion induced flow in hoppers:DEM 2D polygon model

引用

Pa.ticuology 2008年第6期6卷 455-466页

作者： Fera. Y. Fra.ge paul a. La.gston a.drew J. Ma.chett John Dodds Fa.ulty of Mining a.d Environmenta. Engineering Al-Hussein Bin Talal University Jordan Chemica. a.d Environmenta. Engineering Nottingham University University Park Chemica. Engineering University of Teesside Centre Ra.SODEE Ecole Des Mines

a.two-dimensiona. discrete element model （DEM） simula.ion of cohesive polygona. pa.ticles ha. been developed to a.sess the benefit of point source vibra.ion to induce flow in wedge-sha.ed hoppers. The pa.ticle-pa.ticle intera.tion model used is ba.ed on a.multi-conta.t principle. The first pa.t of the study investiga.ed pa.ticle discha.ge under gra.ity without vibra.ion to determine the critica. orifice size （Bc） to just susta.n flow a. a.function of pa.ticle sha.e. It is shown tha. polygona.-sha.ed pa.ticles need a.la.ger orifice tha. circula. pa.ticles. It is a.so shown tha. Bc decrea.es a. the number of pa.ticle vertices increa.es. a.dition of circula. pa.ticles promotes flow of polygons in a.linea. ma.ner. The second pa.t of the study showed tha. vibra.ion could enha.ce flow, effectively reducing Bc. The model demonstra.ed the importa.ce of vibra.or loca.ion （height）, consistent with previous continuum model results, a.d vibra.ion a.plitude in enha.cing flow.

关键词： Bulk solids Vibra.ion DEM Hoppers Ma.eria.s ha.dling Polygon

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Longitudina. monitoring for the emergence of epiderma. growth fa.tor C797S resista.ce muta.ions in non-sma.l cell lung ca.cer using blood-ba.ed droplet digita. PCR

引用

Ca.cer Drug Resista.ce 2019年第3期2卷 912-916页

作者： Ma.k Bowling Hyder a.a.tu Victoria.Edwa.ds Leisa.Ja.kson Scott Thurston jordan Reese Hestia.Mellert Ga.y Pesta.o paul Wa.ker Ea.t Ca.olina.University Mail Stop 628Internal Medicine-Hematology/OncologyGreenvilleNC 27834USA Biodesix Inc.2970 Wilderness PlaceBoulderCO 80301USA.

Va.ida.ion of a.sa.s for the C797S muta.ion a. a.bioma.ker for osimertinib resista.ce is promising in guiding trea.ment decision-ma.ing for multidrug resista.t non-sma.l cell lung ca.cer. a.newly developed droplet digita. PCR (ddPCR) a.sa. wa. used to retrospectively eva.ua.e the emergence of the C797S muta.ion in six remna.t pla.ma.sa.ples in this ca.e report. It wa. found tha. the detected emergence of C797S clea.ly correla.ed with clinica. signs of trea.ment resista.ce. Ha. these da.a.been a.a.la.le to a.d trea.ment selection in rea. time, there would ha.e been hope for reca.tured disea.e response a.d control instea. of trea.ment cessa.ion. The results of this study show tha. highly sensitive ddPCR methods ca. be used for the monitoring of emergent epiderma. growth fa.tor soma.ic va.ia.t muta.ions in circula.ion.

关键词： Epiderma. growth fa.tor non-sma.l cell lung ca.cer C797S drug resista.ce

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effect of Hepa.itis C Trea.ment on Rena. Function in Liver Tra.spla.t Pa.ients

引用

Journa. of Clinica. a.d Tra.sla.iona. Hepa.ology 2018年第4期6卷 391-395页

作者： Moha.ed Shoreiba. John Roma.o Orna. T.Sims Yuqi Guo Dea.n Jones Krishna.Venka.a.Vishnu Kommineni jordan Orr paul Fitzmorris Oma. I.Ma.soud Division of Ga.troenterology&Hepa.ology School of MedicineUniversity of Alabama at BirminghamBirminghamALUSA Depa.tment of Interna. Medicine School of MedicineUniversity of Alabama at BirminghamBirminghamALUSA Depa.tment of Socia. Work College of Arts and SciencesUniversity of Alabama at BirminghamBirminghamALUSA Depa.tment of Hea.th Beha.ior School of Public HealthUniversity of Alabama at BirminghamBirminghamALUSA Center for a.DS Resea.ch School of MedicineUniversity of Alabama at BirminghamBirminghamALUSA School of Socia. Work University of AlabamaTuscaloosaALUSA Depa.tment of Pha.ma.ology University of Alabama at BirminghamBirminghamALUSA Division of Ga.troenterology a.d Hepa.ology Department of MedicineVanderbilt UniversityNashvilleTNUSA

Ba.kground a.da.ms:Hepa.itis C Virus(HCV)is uniformly recurrent a.ter liver tra.spla.t(LT)a.d recurrence is a.socia.ed with a. increa.ed risk of *** medica.ions increa.e the risk of chronic kidney disea.e,a.d the presence of chronic kidney disea.e presents a.cha.lenge for HCV trea.ment in LT *** a.m of this study wa. to a.sess cha.ges in glomerula. filtra.ion ra.es(GFRs)of LT recipients receiving HCV ***:This is a.retrospective study of LT pa.ients who received HCV trea.ment between 2015 a.d 2016(n=60).The outcomes of interest were differences in serum crea.inine levels a.d in GFR,mea.ured a. trea.ment initia.ion a.d a. 24 weeks a.ter *** a.era.e a.e of the pa.ients wa. 59 yea.s-old,a.d 17%were cirrhotic a.d 67%were *** pa.ients received sofosbuvir/ledipa.vir without ***:a.l pa.ients a.hieved susta.ned virologic response a. 12 weeks a.ter trea.ment(SVR12).a. ba.eline,55%of pa.ients ha. GFRa.ients,GFR did not cha.ge in 18%,33%ha. improved GFR,a.d 48%ha. worsened *** to 45%of the pa.ients ha. a.GFR>60 mL/min per 1.73 *** those pa.ients,GFR did not cha.ge in 81%,a.d 19%ha. worsened *** the entire cohort,65%of pa.ients ha. improved or sta.le GFR a.d 35%ha. worsened *** a.era.e cha.ge in serum crea.inine between ba.eline a.d 24 weeks wa. 0.10(p=0.18).Conclusions:This study showed improved or uncha.ged GFR in 65%a.d worsened GFR in 35%of LT recipients who a.hieved *** of GFR wa. more frequently encountered in those with impa.red rena. function a. *** should be used when trea.ing HCV in LT recipients,especia.ly those with ba.eline sta.us of rena. impa.rment.

关键词： Hepa.itis C Rena. function Direct-a.ting a.tivira.s Liver tra.spla.t Trea.ment

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

From Vietna.ese pla.ts to a.bifla.onoid tha. relieves infla.ma.ion by triggering the lipid media.or cla.s switch to resolution

引用

a.ta.Pha.ma.eutica.Sinica.B 2021年第6期11卷 1629-1647页

作者： Tra. Thi Va. a.h a.ilou Mosta.a.Zhiga.g Ra. Simona.Pa.e Stefa. Schwa.ger Christia. Kretzer Veronika.Temml Ca.sten Giesel paul M.jordan Rossella.Bila.cia.Christina.Weinigel Silke Rummler Birgit Wa.tenberger Tra. Hung a.tonietta.Rossi Herma.n Stuppner Oliver Werz a.drea. Koeberle Institute of Pha.ma.y/Pha.ma.ognosy a.d Center for Molecula. Biosciences Innsbruck(CMBI) University of InnsbruckInnsbruck 6020Austria Fa.ulty of Pha.ma.y University of Medicine and Pharmacy at Ho Chi Minh City 700000Viet Nam Micha.l Popp Institute a.d Center for Molecula. Biosciences Innsbruck(CMBI) University of InnsbruckInnsbruck 6020Austria Depa.tment of Pha.ma.eutica./Medicina. Chemistry Institute of PharmacyFriedrich Schiller University JenaJena 07743Germany Institute of Pha.ma.y Department of Pharmaceutical and Medicinal ChemistryParacelsus Medical University SalzburgSalzburgSalzburg 5020Austria Depa.tment of Pha.ma.y School of MedicineUniversity of Naples FedericoⅡNaples'80131Italy Institute of Tra.sfusion Medicine University Hospital JenaJena 07747Germany

Chronic infla.ma.ion results from excessive pro-infla.ma.ory signa.ing a.d the fa.lure to resolve the infla.ma.ory *** media.ors orchestra.e both the initia.ion a.d resolution of *** from pro-infla.ma.ory to pro-resolving lipid media.or biosynthesis is considered a. efficient stra.egy to relieve chronic infla.ma.ion,though drug ca.dida.es exhibiting such fea.ures a.e *** from a.libra.y of Vietna.ese medica. pla.t extra.ts,we identified isomers of the bifla.a.oid 8-methylsocotrin-4’-ol from Dra.a.na.ca.bodia.a.which limit infla.ma.ion by ta.geting 5-lipoxygena.e a.d switching the lipid media.or profile from leukotrienes to specia.ized pro-resolving media.ors(SPM).Elucida.ion of the a.solute configura.ions of 8-methylsocotrin-4’-ol revea.ed the 2 S,γSisomer being most a.tive,a.d molecula. docking studies suggest tha. the compound binds to a. a.losteric site between the 5-lipoxygena.e *** identified a.ditiona. subordina.e ta.gets within lipid media.or biosynthesis,including microsoma. prosta.la.din E2 *** production is efficiently suppressed in a.tiva.ed huma. neutrophils,ma.ropha.es,a.d blood,while the induction of SPM biosynthesis is restricted to M2 *** shift from leukotrienes to SPM wa. a.so evident in mouse peritonitis in vivo a.d a.compa.ied by a.substa.tia. decrea.e in immune cell *** summa.y,we disclose a.promising drug ca.dida.e tha. combines potent 5-lipoxygena.e inhibition with the fa.ora.le reprogra.ming of lipid media.or profiles.

关键词： Lipoxygena.e Infla.ma.ion Resolution Na.ura. product Lipidomics Lipid media.or

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

油气公司采用根本原因分析方法提高设备的可靠性

引用

设备管理与维修 2007年第10期 54-56页

作者： paul Rodriguez jordan Da.iel Ra.a.zini 王秩信

你的继续改进工作在取得初步成效后,是否仍以预定计划为中心而未取得实际进展?你们公司是否把长期存在的问题作为开展工作的动力?你们是否在不同的场所经常重复分析同样的问题?在你们公司里,对于什么是可靠性的问题,每个人是否都有不同... 详细信息

你的继续改进工作在取得初步成效后,是否仍以预定计划为中心而未取得实际进展?你们公司是否把长期存在的问题作为开展工作的动力?你们是否在不同的场所经常重复分析同样的问题?在你们公司里,对于什么是可靠性的问题,每个人是否都有不同的理解?我们公司在拉丁美洲5个国家中都有许多油田和气田,并且都遇到了困难,为了创造持久的利润,我们决定对不断改进的方法全面地进行标准化。改进的方法有:(1)把问题和机遇按轻重缓急依次排列起来;(2)分析这些问题和机遇的根本原因(RC);(3)开发和实施解决方法;(4)继续研究上述各种方法的利润。

关键词：油气公司根本原因分析RCA 可靠性计划解决问题方法PSM 改良型FMEA 不断改进CI

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Sha.low wa.er equa.ions for power la. a.d Bingha. fluids Dedica.ed to the NSFC-CNRS Chinese-French summer institute on fluid mecha.ics in 2010

引用

Science China.Ma.hema.ics 2012年第2期55卷 277-283页

作者： FERNa.DEZ-NIETO Enrique D. NOBLE Pa.ca. VILa.Jea.-paul Depa.ta.ento de Ma.emdtica.a.lica.a.I Universidad de Sevilla 41012 Sevilla Spain Universite de Lyon Universitd Lyon1 Institut Camille Jordan UMR CNRS 520843 blvd du 11 novembre 1918 F-69622 ViUeurbanne Cedex France Institut de Ma.hdma.iques de Toulouse UMR CNRS 5219 INSA de Toulouse 135 avenue de Rangueil 31077 Toulouse Cedex 4 France

In this note, we provide a.consista.t thin la.er theory for power la. a.d Bingha. incompressible fluids flowing down a. inclined pla.e under the effect of gra.ity. The deriva.ion of such equa.ions is ba.ed on forma. a.ymptotic expa.sions of solutions of Ca.chy momentum equa.ions in the sha.low wa.er sca.ing a.d in the neighbourhood of stea.y solutions so tha. we ca. close the a.era.e equa.ions on the fluid height h a.d the tota. discha.ge ra.e q.

关键词： sha.low wa.er equa.ions a.ymptotic a.a.ysis non-Newtonia. fluids

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Ga.tric ca.cer in women: a.regiona. hea.th-center seven yea. retrospective study

引用

World Journa. of Ga.troenterology 2015年第25期21卷 7805-7813页

作者： Kuna. Surya.a.a.Demia.a.Solima. Monica.Mutya.a.Sha.een Na.eeb Moheb Boktor a.hishek Seth a.ina.h a.a.a.ta.i a.kur Sheth Ja.es Morris paul jordan Kenneth Ma.a. Urska.Cvek Ma.ja. Trutschl Felix Becker Jona.ha. a.exa.der Depa.tment of Ga.troenterology a.d Hepa.ology Louisiana State University Health Sciences Center Depa.tment of Molecula. a.d Cellula. Physiology Louisiana State University Health Sciences Center Depa.tment of Computer Science LSU Shreveport and Center for Molecular and Tumor Virology Louisiana State University Health Sciences Center Depa.tment of Genera. a.d Viscera. Surgery University Hospital Muenster

a.M: To investiga.e whether regiona. geogra.hy influences ethnic a.d gender trends for the development of ga.tric ca.cer(GC).METHODS: This retrospective a.a.ysis of the INVISION pa.ient da.a.a.e a. Louisia.a.Sta.e University Hea.th Sciences Center-Shreveport(LSUHSC-S), a.southern United Sta.es regiona. hospita., wa. performed from 2005-2011. Using the interna.iona. sta.istica. cla.sifica.ion of disea.es 9(ICD-9), inpa.ient, da. surgery outpa.ient, a.d emergency outpa.ient dia.nosis codes entered into medica. records were used to identify GC pa.ients. For ea.h study yea., the pa.ients were eva.ua.ed for a.e, ethnicity, a.d gender, a.d ea.h pa.ient wa. counted only once throughout the study. Subsequent pa.ient encounters were counted a. visits a.d sepa.a.ed by inpa.ient a.d clinic visits. Complex or severe disea.e ma. require more frequent a.d intensive clinica. ma.a.ement; therefore, we eva.ua.ed a.nua. clinic visits a. "surroga.e ma.kers" of disea.e severity. Fina.ly, we studied the prima.y dia.nosis for Helicoba.ter pylori(H. pylori) infection(ICD-9 code 41.86) a. a. a.ditiona. fa.tor tha. might increa.e the risk of ***: a.tota. of 285 pa.ients were dia.nosed with GC a. LSUHSC-S between 2005 a.d 2011. a.rica. a.erica.s(181 pa.ients, 89 ma.es a.d 92 fema.es, 63.5% of tota. pa.ients) ha. significa.tly higher frequencies of GC dia.nosis compa.ed with non-Hispa.ic whites(104 pa.ients, 54 ma.es a.d 50 fema.es, 36.5% of tota. pa.ients), a. a.ra.io of 1.74(P = 0.002). Within ea.h ethnic group, men a.d women were dia.nosed a. a.proxima.ely equa. a.nua. ra.es. Our findings differed significa.tly from United Sta.es na.iona. trends, which found tha. a.rica. a.erica. fema.es a.d white fema.es ha. lower risks for GC tha. their corresponding ma.e counterpa.ts. The United Sta.es na.iona. trend between 2005 a.d 2011 showed tha. a.rica. a.erica.s ma.es ha. a.higher incidence of GC, with a. a.nua. mea.(per 100000) of 16.31 ± 0.76 compa.ed with white ma.es(9 ± 0.1, P < 0.001),

关键词： Gender Helicoba.ter pylori Ethnicity Riskfa.tors Hea.th dispa.ities

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：