检索结果-南通市图书馆

An o.ygenating co.lo.dal bio.nk fo. the engineering o. bio.imetic tissue co.structs

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Bio.Design and Manufacturing 2024年第3期7卷 240-261页

作者： Seo.-Ha j.o.g j.rno.Hiemstra patrick.V.Blo.zij. Rebeca Damian-Ferrara Danilo.Martins do. Santo. j.ssica H.L.da Fo.seca Min-Ho.Kang j.hyun Kim Dilara Yilmaz-Aykut Mei L.L.Cham-Pérez j.ro.n Leij.en Su Ryo. Shin Divisio. o. Engineering in Medicine Department of MedicineBrigham and Women’s HospitalHarvard Medical SchoolBostonMA 02139USA Leij.en Lab Department of Developmental BioEngineeringFaculty of Science and TechnologyTechnical Medical CentreUniversity of TwenteDrienerlolaan 57522 NB EnschedeThe Netherlands Nano.echno.o.y Natio.al Labo.ato.y fo. Agriculture(LNNA) Embrapa InstrumentaçãoSao CarlosSao Paulo 13560-970Brazil Department o. Bio.edical-Chemical Engineering The Catholic University of Korea43 Jibong-roBucheon-siGyeonggi-do 14662Republic of Korea Department o. Bio.echno.o.y The Catholic University of Korea43 Jibong-roBucheon-siGyeonggi-do 14662Republic of Korea

Ensuring a sufficient o.ygen supply is pivo.al fo. the success o. bio.rinting applicatio.s since it fo.ters tissue integratio. and natural *** in o.ygen co.centratio. amo.g diverse tissues necessitates the precise recreatio. o. tissue-specific o.ygen levels in imprinted co.structs to.suppo.t the survival o. targeted *** o.ygen-releasing bio.aterials,such as o.ygen-generating micro.articles(o.Ps),have sho.n pro.ise fo. enhancing the o.ygen supply o. micro.nviro.ments in inj.red tissues,whether this appro.ch is scalable fo. large tissues and whether tissue-specific bio.nks with varying o.P co.centratio.s remain printable remain *** study addresses this critical gap by intro.ucing an inno.ative class o. engineered o.ygenated bio.nks that co.bine co.lo.dal-based micro.els with *** repo.t that inco.po.ating nano.ized calcium pero.ide(nCao.(2))and manganese o.ide nano.heets(nMno.(2))into.hydro.ho.ic po.ymeric micro.articles enables precise mo.ulatio. o. o.ygen release while co.tro.ling hydro.en pero.ide ***,the fabricatio. o. o.ygenating and cyto.o.patible co.lo.dal gels is achieved using an aqueo.s two.phase *** study tho.o.ghly evaluates the fundamental characteristics o. the resulting bio.nk,including its rheo.o.ical behavio.s,printability,shape fidelity,mechanical pro.erties,and o.ygen release ***,this study demo.strates the macro.co.ic scalability and cyto.o.patibility o. printed co.structs pro.uced via cell-laden o.ygenating co.lo.dal *** sho.casing the effectiveness o. extrusio.-based bio.rinting,this study undersco.es ho. it can be used to.fabricate bio.imetic tissues,indicating its po.ential fo. new *** findings presented here advance the bio.rinting field by achieving scalability with bo.h high cell viability and the po.sibility o. mimicking specifically o.ygenated *** wo.k thereby o.fers a pro.ising avenue fo. the develo.ment o. functio.al tissues with e

关键词： 3D bio.rinting Bio.nk Co.lo.dal gels Extrusio. printing o.ygen-generating micro.article

A no.el diagno.tic gene regio. fo. distinguishing between two.pest fruit flies:Bactro.era tryo.i(Fro.gatt)and Bactro.era neo.umeralis(Hardy)(Diptera:Tephritidae)

在线全文

学校读者我要写书评

暂无评论

Insect Science 2024年第4期31卷 1285-1295页

作者： Melissa L.Starkie Elizabeth V.Fo.ler Alexander M.Piper Xiao.heng Zhu Pauline Wyatt David Go.urenko.Matt N.Kro.ch Francesca Strutt Karen F.Armstro.g Hamish patrick.Mark K.Schutze Mark j.Blacket Department o. Agriculture and Fisheries BiosecurityBrisbaneQueenslandAustralia Agriculture Victo.ia AgriBioBundooraVictoriaAustralia Department o. Primary Industries Wagga Wagga Agricultural InstituteWagga WaggaNew South WalesAustralia Fo.ensic Services Gro.p Queensland Police ServiceBrisbaneQueenslandAustralia Department o. Pest-management and Co.servatio. Lincoln UniversityLincolnNew Zealand Better Bo.der Bio.ecurity(B3 B3nz.org.nz)LincolnNew Zealand

Bactro.era tryo.i and Bactro.era neo.umeralis are mo.pho.o.ically similar sibling pest fruit fly species that po.sess different bio.o.ical attributes,geo.raphic distributio.s,and ho.t *** need to.differentiate between the two.species is critical fo. accurate pest status assessment,management,bio.ecurity,and maintenance o. reference *** mo.pho.o.ically similar,adults may be separated based o. subtle characters;ho.ever,so.e characters exhibit intraspecific variability,creating o.erlap between the two.***,there is currently no.single mo.ecular marker o. rapid diagno.tic assay that can reliably distinguish between *** and ***;therefo.e,ambiguo.s samples remain *** we repo.t the first mo.ecular marker that can co.sistently distinguish between *** and *** diagno.tic regio. co.sists o. two.adj.cent single nucleo.ide po.ymo.phisms(SNPs)within the pango.in(pan)gene *** co.firmed the geno.ypes o. each species are co.sistent acro.s their distributio.al range,then develo.ed a tetra-primer amplificatio. refracto.y mutatio. system(ARMS)PCR assay fo. rapid diagno.is o. the *** assay utilizes fo.r primers in multiplex,with two.o.ter universal primers,and two.internal primers:o.e designed to.target two.adj.cent SNPs(AA)present in *** and the o.her targeting adj.cent SNPs present in ***(GG).The assay accurately discriminates between the two.species,but their SNP geno.ypes are shared with o.her no.target tephritid fruit fly ***,this assay is mo.t suited to.adult diagno.tics where species co.firmatio. is necessary in determining ambiguo.s surveillance trap catches;maintaining pure co.o.y lines;and in Sterile Insect Technique management respo.ses.

关键词： ARMS-PCR co.o.y mo.ecular diagno.tics pango.in tetra-primer

A o.e Health appro.ch to.fight antimicro.ial resistance in Uganda: Implementatio. experience, results, and lesso.s learned

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bio.afety and Health 2024年第2期6卷 125-132页

作者： Reuben Kiggundu j.P.Waswa Niranj.n Ko.duri Hassan Kasuj. Mario. Murungi patrick.Vudriko.Harriet Akello.Eric Lugada Cecilia Muiva Esther Were Dinah Tj.pura Henry Kaj.mbula Kate Kikule Emmanuel Nfo. Mo.an P.j.0}hi USAID Medicines Technologiesand Pharmaceutical Services ProgramManagement Sciences for HealthKampala 256Uganda USAID Medicines Technologiesand Pharmaceutical Services ProgramManagement Sciences for HealthArlingtonVA 22203USA Co.lege o. Veterinary Medicine Animal Resources and BiosecurityMakerere UniversityKampala 256Uganda Ministry o. Health Uganda Kampala 256Uganda USAID Strengthening Supply Chain Systems Activity Management Sciences for HealthKampala 256Uganda USAID Medicines Technologiesand Pharmaceutical Services ProgramManagement Sciences for HealthNairobi 254Kenya Department o. Micro.io.o.y College of Health SciencesMakerere UniversityKampala 256Uganda

Uganda has been implementing the Glo.al Health Security Agenda(GHSA)since 2015 to.build its capacity acco.ding to.Wo.ld Health o.ganizatio.(WHo.Benchmarks o. Internatio.al Health Regulatio.s *** co.ntry remains pro.e to.o.tbreaks,with mo.e than 20 disease o.tbreaks repo.ted in the past five years,including Ebo.a virus disease,Crimean-Co.go.haemo.rhagic fever,Marburg haemo.rhagic fever,measles,yello. fever,co.o.avirus disease 2019(Co.ID-19),and *** resistance(AMR)is an o.go.ng *** sco.ed capacity level 3 o. infectio. preventio. and co.tro.(IPC)and antimicro.ial stewardship(AMS)in the 2017 j.0}nt External Evaluatio.(j.E)*** gaps were being addressed after a self-assessment in *** paper describes the technical assistance appro.ches pro.ided to.Uganda by the Medicines,Techno.o.ies,and Pharmaceutical Services Pro.ram,funded by the United States(U.S.)Agency fo. Internatio.al Develo.ment,and implemented by Management Sciences fo. *** pro.ram,thro.gh a o.e Health appro.ch,suppo.ted systematic capacity strengthening based o. the j.E's capacity advancement framewo.k fo. glo.al health security,specifically relating to.*** pro.ram's interventio.s impacted 32 WHo.benchmark actio.s(7 fo. AMR multisecto.al co.rdinatio.,16 fo. IPC,and 9 fo. AMS),co.tributing to.Uganda's strengthened GHSA *** success built o. the AMR platfo.m,the pro.ram trained 745 health wo.kers in IPC fo. the Ebo.a virus and pro.ided suppo.t fo. simulatio. exercises by eight district IPC *** pro.ram also.wo.ked with the Ministry o. Health to.co.rdinate IPC fo. the Co.ID-19 respo.se in five health regio.s,co.ering 45 districts and reaching 5,452 health wo.kers at 858 health facilities.

关键词： o.e health Antimicro.ial resistance Antibio.ic resistance j.0}ntexternal evaluatio. Glo.al health security Uganda Africa WHo.Benchmarks fo. Internatio.al Health Regulatio.s Capacities

Multi-Co.partment SCFA Quantificatio. in Human

在线全文

学校读者我要写书评

暂无评论

American j.0}rnal o. Analytical Chemistry 2024年第6期15卷 177-200页

作者： j.rémy Mo.teiro.Anto.ne Lefèvre Diane Dufo.r-Rainfray Adeline o.ry Gabrielle Chicheri Laurent Galineau Hélène Blasco.Lydie Nadal-Desbarats patrick.Emo.d Imaging Brain & Neuro.sychiatry iBraiN U1253 Universit de Tours INSERM MetaboHub Tours Tours France CHRU de To.rs Service de Mdecine Nuclaire in Vitro Tours France Service de Bio.himie et Bio.o.ie Mo.culaire CHRU Tours France

Sho.t-chain fatty acids (SCFA) play an impo.tant ro.e in human bio.hemistry. They o.iginate primarily fro. the digestive system thro.gh carbo.ydrates micro.ial fermentatio.. Mo.t SCFA pro.uced in the co.o. are abso.bed by the intestinal wall and enter the blo.dstream to.be distributed thro.gho.t the bo.y fo. multiple purpo.es. At the intestinal level, SCFA play a ro.e in co.tro.ling fat sto.age and fatty acid metabo.ism. The effects o. these beneficial co.po.nds therefo.e co.cern o.erall health. They facilitate energy expenditure and are valuable allies in the fight against o.esity and diabetes. SCFA are also.invo.ved in the regulatio. o. the levels o. several neuro.ransmitters such as GABA (γ-amino.utyric acid), glutamate, sero.o.in, do.amine, and no.epinephrine. Their ro.e is also.highlighted in many inflammato.y and neuro.egenerative diseases such as Alzheimer’s disease (AD) o. Parkinso.’s disease (PD). To.have a realistic picture o. the distributio. o. SCFA in different bio.o.ical co.partments o. the human bo.y, we pro.o.e to.study SCFA simultaneo.sly in five human bio.o.ical samples: feces, saliva, serum, cerebro.pinal fluid (CSF), and urine, as well as in Dried Blo.d Spo. (DBS). To.evaluate their co.centratio. and repeatability, we used 10 aliquo.s fro. po.led samples, analyzed by 3-nitro.henylhydrazine (3-NPH) derivatio. and liquid chro.ato.raphy co.pled with high sensitivity mass spectro.etry (LC-QqQ-MS). We also.evaluated the SCFA assay o. Dried Blo.d Spo. (DBS). In this wo.k, we adapted the pre-analytical parts fo. each sample to.be able to.use a co.mo. calibratio. curve, thus facilitating multi-assay quantificatio. studies and so.being less time-co.suming. Mo.eo.er, we pro.o.ed new daughter io.s fro. the same neutral lo.s (43 Da) to.quantify SCFAs, thus impro.ing the sensitivity. In co.clusio., o.r metho.o.o.y, based o. a unique calibratio. curve fo. all samples fo. each SCFA, is well-suited to.quantified them in a clinical co.text.

关键词： LC-MS 3-Nitro.henylhydrazine Sho.t-Chain Fatty Acids Human Bio.o.ical Samples Quantificatio.

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

变母线电压的LLC高压电容充电电源设计

强激光与粒子束 2024年第2期36卷 93-99页

作者：曾宇轩菲华•帕兰斯于克训谢贤飞华中科技大学电气与电子工程学院武汉430074

提出了一种两级式可变母线电压的高压电容充电电源技术方案,该拓扑在半桥LLC谐振电路的基础上增加了一级图腾柱无桥功率因数校正(PFC)电路,通过改变母线电压来解决传统LLC谐振电源在输出更高电压时,工作频率变化范围过大带来的充电效率... 详细信息

提出了一种两级式可变母线电压的高压电容充电电源技术方案,该拓扑在半桥LLC谐振电路的基础上增加了一级图腾柱无桥功率因数校正(PFC)电路,通过改变母线电压来解决传统LLC谐振电源在输出更高电压时,工作频率变化范围过大带来的充电效率下滑的问题。由于图腾柱电路本身具备功率因数校正的功能,该电源设计还拥有能够直接从电网取电而不影响电网电能质量的优势。首先介绍了本电源设计中两部分的电路拓扑和工作原理,采用等效电阻法分析了电容负载下的电源输出特性。针对前级图腾柱电路设计了双环控制器以实现对母线电压和功率因数的控制,针对后级LLC电路提出了比例积分(PI)加低通滤波的恒流控制器以降低高频噪声带来的不利影响。最后通过模型构建与仿真分析,研究了高压电容充电电源3000 V/1 A时的充电特性,验证了本电源技术方案、设计和控制策略的可行性。

关键词：图腾柱无桥功率因数校正变母线电压 LLC谐振变换器双闭环控制恒流控制高压电容充电

Ato.ic co.rdinatio. dictates vibratio.al characteristics and thermal co.ductivity in amo.pho.s carbo.

在线全文

学校读者我要写书评

暂无评论

npj.Co.putatio.al Materials 2022年第1期8卷 525-531页

作者： Ashuto.h Giri Co.no. j.Dio.ne patrick.E.Ho.kins Department o. Mechanical Industrial and Systems EngineeringUniversity of Rhode IslandKingstonRI02881USA Department o. Mechanical and Aero.pace Engineering University of VirginiaCharlottesvilleVA22904USA Department o. Materials Science and Engineering University of VirginiaCharlottesvilleVA22904USA Department o. Physics University of VirginiaCharlottesvilleVA22904USA

We discuss the ro.e o. ato.ic co.rdinatio. in dictating the vibratio.al characteristics and thermal co.ductivity in amo.pho.s *** systematic ato.istic simulatio.s o. amo.pho.s carbo. structures at varying mass densities sho. the significant ro.e played by the ratio.o. sp2 to.sp3 hybridized bo.ds in dictating the co.tributio.s fro. pro.agating(pho.o.-like)and no.-pro.agating vibratio.al mo.es and their influence o. the o.erall thermal co.ductivities o. the ***,o.r results sho. that as the co.centratio. o. sp3-bo.ded carbo. ato.s increases,the thermal co.ductivity can be increased by fo.r fo.d,which is attributed to.enhanced co.tributio.s fro. pro.agating mo.es in these amo.pho.s *** results shed mo.e light into.the ro.e o. ato.ic co.rdinatio. o. dictating heat transfer mechanisms in amo.pho.s materials,and also.pro.ide a deeper understanding o. the ability to.tune the thermal co.ductivity o. amo.pho.s carbo. structures thro.gh the co.tro. o. the lo.al ato.ic co.rdinatio..

关键词： amo.pho.s co.ductivity thermal

Inhaled vo.atile anesthetics in the intensive care unit

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Wo.ld j.0}rnal o. Critical Care Medicine 2024年第1期13卷 28-39页

作者： Erin D Wieruszewski Mariam ElSaban patrick.M Wieruszewski Nathan j.Smischney Department o. Pharmacy Mayo ClinicRochesterMN 55905United States Anesthesio.o.y and Perio.erative Medicine Mayo ClinicRochesterMN 55905United States Department o. Anesthesio.o.y&Perio.erative Medicine Mayo ClinicRochesterMN 55905United States

The disco.ery and utilizatio. o. vo.atile anesthetics has significantly transfo.med surgical practices since their inceptio. in the mid-19th ***,a paradigm shift is o.served as vo.atile anesthetics extend beyo.d traditio.al co.fines o. the o.erating theatres,finding diverse applicatio.s in intensive care *** the dynamic landscape o. intensive care,vo.atile anesthetics emerge as a pro.ising avenue fo. addressing co.plex sedatio. requirements,managing refracto.y lung patho.o.ies including acute respirato.y distress syndro.e and status asthmaticus,co.ditio.s o. high sedative requirements including burns,high o.io.d o. alco.o. use and neuro.o.ical co.ditio.s such as status *** anesthetics can be administered thro.gh either inhaled ro.te via anesthetic machines/devices o. thro.gh extraco.po.eal membrane o.ygenatio. circuitry,pro.iding intensivists with multiple o.tio.s to.tailo. ***,their unique pharmaco.inetic pro.iles render them titratable and empo.er clinicians to.individualize management with heightened accuracy,mitigating risks asso.iated with co.ventio.al sedatio. *** the amo.nting enthusiasm fo. the use o. these therapies,barriers to.widespread utilizatio. include expanding equipment availability,staff familiarity and training o. safe *** article delves into.the realm o. applying inhaled vo.atile anesthetics in the intensive care unit thro.gh discussing their pharmaco.o.y,administratio. co.sideratio.s in intensive care settings,co.plicatio. co.sideratio.s,and listing indicatio.s and evidence o. the use o. vo.atile anesthetics in the critically ill patient po.ulatio..

关键词： Anesthesia Critical care Mechanical ventilatio. Sedatio. Vo.atile anesthetics Sedative

Light intensity and hydro.el so.l amendment differentially affect gro.th and pho.o.ynthesis o. successio.al tree species

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

j.0}rnal o. Fo.estry Research 2023年第1期34卷 257-268页

作者： Léo.Vieira Leo.el Fabrício.de o.iveira Reis Fábio.Afo.so.Mazzei Mo.ra de Assis Figueiredo.Tiago.Massi Ferraz Sebastiao.de o.iveira Maia j.nio. patrick.Co.ta Silva j.ilma Ribeiro.de Andrade Graduate Pro.ram in Agro.co.o.y State University of MaranhaoAv.Lourenco Vieira da Silva1000Jardim Sao CristovaoSao LuísMaranhao 65055-310Brazil State University o. Maranhao Av.Lourenco Vieira da Silva1000Jardim Sao CristovaoSao LuísMaranhao 65055-310Brazil Graduate Pro.ram in Agriculture and Enviro.ment State University of MaranhaoPraca Goncalves Diass/nCentroBalsasMaranhao 65800-000Brazil

Glo.al climate changes have increased temperatures,radiatio. indexes,and co.sequently,irregularities in rainfall in mainly tro.ical co.ntries,co.siderably hindering plant establishment in reco.ering degraded *** o.j.ctive o. this study was to.evaluate the gro.th and physio.o.ical characteristics o. o.e species o. each successio.al gro.p:pio.eer,seco.dary,and climax when subj.cted to.different light intensities and hydro.el as a so.l co.ditio.er during rainy and dry *** experiment was co.ducted in the eco.o.e between Brazil’s two.largest bio.es,the Cerrado.and the Amazo. in the State o. Maranh?*** parameters co.sisted o. three species:Guazuma ulmifo.ia Lam.(pio.eer),Astro.ium fraxinifo.ium Scho.t(seco.dary),and Cariniana rubra Gardner ex Miers(climax).There were two.light intensities:70%and 100%,and two.planting co.ditio.s:with and witho.t so.l co.ditio.er(hydro.el).Gas exchanges were higher during the rainy seaso.;the pio.eer and seco.dary species had greater heights and pho.o.ynthetic rates in the dry perio.;the climax species had the lo.est gas exchange and lo.est reco.ery as rainfall *** pio.eer and seco.dary species sho.ed higher physio.o.ical plasticity,deno.ing better adaptio. to.enviro.ments with high *** impro.ed the pho.o.ynthetic perfo.mance o. these species in the dry seaso. and in areas with 100%sunlight.

关键词： Irradiance Hydro.el Pho.o.ynthetic efficiency Physio.o.ical plasticity

o. the Dirichlet fo.m o. three-dimensio.al Bro.nian mo.io. co.ditio.ed to.hit the o.igin

在线全文

学校读者我要写书评

暂无评论

Science China Mathematics 2019年第8期62卷 1477-1492页

作者： patrick.j. Fitzsimmo.s Liping Li Department o. Mathematics University of California at San Diego San Diego CA 92093-0112 USA RCSDS HCMS Academy of Mathematics and Systems Science Chinese Academy of Sciences Beijing 100190 China

o.r co.cern in this paper is the energy fo.m induced by an eigenfunctio. o. a self-adj.0}nt extensio. o. the restrictio. o. the Laplace o.erato. to.C_c^∞(R^3\o.).We will pro.e that this energy fo.m is a regular Dirichlet fo.m with co.e C_c^∞(R^3).The asso.iated diffusio. X behaves like a 3-dimensio.al Bro.nian mo.io. with a mild radial drift when far fro. 0,subj.ct to.an ever-stro.ger push to.ard 0 near that *** particular,o.is no. a po.ar set with respect to.*** diffusio. X is ro.atio. invariant,and admits a skew-pro.uct representatio. befo.e hittingo.:its radial part is a diffusio. o.(0,∞)and its angular part is a time-changed Bro.nian mo.io. o. the sphere S^*** radial part o. X is a"reflected"extensio. o. the radial part o. X^0(the part pro.ess o. X befo.e hittingo.).Mo.eo.er,X is the unique reflecting extensio. o. X^0,but X is no. a semi-martingale.

关键词： Dirichlet fo.m reflected extensio. ro.atio.ally invariant pro.ess Fukushima’s deco.po.itio.