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Particuology 2021年第2期19卷 43-47页

作者： Sisi Yang patrick Ford Sriram Subramanian Dan Single.on j.son Sande.s Ste.he. B.Cronin De.artment of Physics and Astronomy University of Southern CaliforniaLos AngelesCA 90089USA Ming Hsie. De.artment of e.e.trical e.gine.ring University of Southern CaliforniaLos AngelesCA 90089USA Danie. j.e.ste.n De.artment of Industrial&Syste. e.gine.ring University of Southern CaliforniaLos AngelesCA 90089USA Transie.t Plasma Syste.s Inc.TorranceCA 90501USA

It is now re.ognize. that nanoscale.particulate.matte.(PM)re.re.e.ts a substantial he.lth hazard for our socie.y,including PM from re.taurant *** this study,we.e.plore. the.use.of a transie.t pulse. plasma in conj.nction with an applie. DC bias to tre.t oil ae.osols that close.y re.e.ble.re.taurant(i.e.,charbroile.)smoke.*** polyaromatic ole.in PAO-4 and soybe.n oil,we.found that a thre.-orde.-of-magnitude.re.uction in particulate.(i.e.,99.9%re.1}diation)could be.achie.2}d with this ***,the.plasma discharge.was produce. in a 4-in.-diamete. cylindrical re.ctor with a 5-10 ns high voltage.30 kV)pulse.ge.e.ator toge.he. with applie. DC bias voltage. up to 10 *** distribution of nanoparticle.size. was measure. using a scanning mobility particle.size.(SMPS)with diamete. ce.te.e. around 225 ***,the.main mechanism of re.1}diation occurs in a two-ste. proce.s in which the.oil nanoparticle. are.first ionize. by the.fre. e.e.trons and fre. radicals in the.plasma and the. the.charge. particle. are.swe.t out to the.side.alls of the.re.ctor by the.applie. DC *** be.ie.2} this ge.e.al approach ope.s up ne. de.re.s of fre.dom in the.de.ign of e.e.trostatic oil ae.osol pollution control de.ice..

关键词： Nanoparticle. Transie.t plasma Charbroile. e.ission DC bias Re.0}diation

Cluste.ing of prostate.cance. he.lthcare.pathways in the.Fre.ch National He.lthcare.database

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Cance. Innovation 2023年第1期2卷 52-64页

作者： Roméo Baulain j.rémy j.vé Dunia Sakr Marine.Gross‐Goupil Magali Rouye. Marius Pue. patrick Blin Cécile.Droz‐Pe.rote.u Régis Lassalle.Nicolas H.Thurin École.nationale.de.la statistique.e. de.l'administrationéconomique.Paris(e.SAe. Institut Polytechnique ParisPalaiseauFrance Univ.Borde.ux INSERM CIC‐P 1401Bordeaux PharmacoEpiBordeauxFrance medical Oncology Hôpital Saint AndréCHU de BordeauxBordeauxFrance

Background:He.lthcare.pathways of patie.ts with prostate.cance. are.he.e.oge.e.us and comple. to appre.e.d using traditional de.criptive *** and visualization methods can e.hance.the.r ***:Patie.ts with prostate.cance. in 2014 we.e.ide.tifie. in the.Fre.ch National He.lthcare.database.Système National de. Donnée. de.Santé—SNDS)and the.r data we.e.e.tracte. with up to 5 ye.rs of history and 4 ye.rs of follow‐***‐one.spe.ific e.counte.s constitutive of prostate.cance. manage.1}nt we.e.synthe.ize. into four macro‐variable. using a cluste.ing *** value. over patie.t follow‐ups constitute. he.lthcare.*** matching was applie. to calculate.distance. be.we.n *** around medoids was the. use. to de.ine.consiste.t groups across four e.clusive cohorts of incide.t prostate.cance. patie.ts:Hormone.se.sitive(HSPC),metastatic hormone.se.sitive(mHSPC),castration‐re.istant(CRPC),and metastatic castration‐re.istant(mCRPC).Inde. plots we.e.use. to re.re.e.t pathways ***:The.re.artition of macro‐variable. value.—surveillance.local tre.tment,androge.ic de.rivation,and advance. tre.tment—appe.re. to be.consiste.t with prostate.cance. *** to five cluste.s of he.lthcare.pathways we.e.obse.ved in e.ch of the.diffe.e.t cohorts,corre.ponding for most of the. to re.e.ant clinical patte.ns,although some he.e.oge.e.ty *** instance.cluste.ing allowe. to distinguish patie.ts unde.going active surveillance.or tre.te. according to cance. progre.sion risk in HSPC,and patie.ts re.e.ving tre.tment for pote.tially curative or palliative purpose. in mHSPC and ***:Visualization methods combine. with a cluste.ing approach e.able. the.ide.tification of clinically re.e.ant patte.ns of prostate.cance. *** of the.e.care.pathways is an e.se.tial e.e.1}nt for the.compre.e.sion and the.robust asse.sment of he.lthcare.te.hnology e.fe.tivene.s.

关键词： prostate.cance. he.lthcare.pathway cluste.ing machine.le.rning SNDS

Nature.大规模研究揭示生命所必需的基因

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现代生物医学进展 2016年第31期16卷 I0002-I0003页

作者： Dickinson, Mary e. Fle.nike., Ann M. j., Xiao Te.oul, Lydia Wong, Michae. D. White. j.cque.ine.K. mee.an, Te.re.ce.F. We.inge., Wolfgang j. We.te.be.g, He.rik Adissu, Hibre. Bake., Candice.N. Bowe., Lyne.te.Brown, j.me. M. Caddle. L. Brianna Chiani, France.co Clary, Dave Cle.k, j.me. Daly, Mark j. De.e.re. j.me. M. Doe. Bre.dan Dolan, Mary e. e.ie. Sarah M. Fuchs, He.mut Gailus-Durne., Vale.ie.Galli, Antone.la Gambadoro, Ale.sia Galle.os, j.an Guo, Shiying Horne., Ne.l R. Hsu, Chih-We. j.hnson, Sara j. Kalaga, Sowmya Ke.th, Lance.C. Lanoue. Louise.Lawson, Thomas N. Le., Monkol Mark, Manue. Arschall, Susan M. Mason, j.re.y Mce.we., melissa L. Ne.bigging, Susan Nutte., Lauryl M. j. Pe.e.son, Ke.in A. Ramire.-Solis, Ramiro Rowland, Douglas j. Ryde., e.ward Samocha, Kaitlin e. Se.vitt, j.hn R. Se.loum, Mohammed Szoke.Kovacs, Zsombor Tamura, Masaru Trainor, Amanda G. Tudose. Ilinca Wakana, Shige.aru Warre., j.nathan We.dling, Olivia We.t, David B. Wong, Le.ye.n Yoshiki, Atsushi MacArthur, Danie. G. Tocchini-Vale.tini, Glauco P. Gao, Xiang Flice., Paul Bradle., Allan Skarne., William C. j.stice. Monica j. Parkinson, He.e. e. Moore. Mark We.ls, Sara Braun, Robe.t e. Svenson, Kare. L. de.Ange.is, Martin Hrabe.He.ault, Yann Mohun, Tim Mallon, Ann-Marie.He.ke.man, R. Mark Brown, Ste.5} D. M. Adams, David j. Lloyd, K. C. Ke.t McKe.lie. Colin Be.ude., Arthur L. Bucan, Maj. Murray, Ste.he. A. De.t Mol Physiol & Biophys Houston TX 77030 USA Toronto Ctr Phe.oge. Toronto ON M5T 3H7 Canada Mt Sinai Hosp Toronto ON M5G 1X5 Canada Univ Pe.n Perelman Sch Med Genom & Computat Biol Program Philadelphia PA 19104 USA med Re. Council Harwe.l Mammalian Genet Unit Harwell OX11 0RD Oxon England Mary Lyon Ctr Harwell OX11 0RD Oxon England Hosp Sick Childre. Mouse Imaging Ctr Toronto ON M5T 3H7 Canada We.lcome Trust Sange. Inst Wellcome Trust Genome Campus Cambridge CB10 1SA England e.rope.n Bioinformat Inst European Mol Biol Lab Wellcome Trust Genome Campus Cambridge CB10 1SD England med Univ Vie.na Ctr Anat & Cell Biol A-1090 Vienna Austria Hosp Sick Childre. 555 Univ Ave Toronto ON M5G 1X8 Canada j.ckson Lab 600 Main St Bar Harbor ME 04609 USA Univ Calif Davis Mouse Biol Program Davis CA 95618 USA Italian Natl Re. Council CNR Inst Cell Biol & Neurobiol Monterotondo Mouse Clin I-00015 Monterotondo Italy Massachuse.ts Ge. Hosp Analyt & Translat Genet Unit Boston MA 02114 USA Broad Inst MIT & Harvard Program Med & Populat Genet Cambridge MA 02142 USA Ge.man Re. Ctr e.vironm Hlth Helmholtz Zentrum Munchen Inst Expt Genet D-85764 Neuherberg Germany Ge.man Mouse.Clin D-85764 Neuherberg Germany Baylor Coll med Dept Mol & Human Genet Houston TX 77030 USA Nanj.ng Univ Nanjing Biomed Res Inst Collaborat Innovat Ctr Genet & Dev SKL Pharmaceut Biotechnol & Model Anim Res Ctr Nanjing 210061 Jiangsu Peoples R China Univ Strasbourg ICS Infrastruct Natl PHENOMIN F-67404 Illkirch Graffenstaden France Univ Strasbourg INSERM CNRS IGBMC F-67404 Illkirch Graffenstaden France RIKe. BioResource Ctr Tsukuba Ibaraki 3050074 Japan Childre.s Hosp Oakland Res Inst Oakland CA 94609 USA IMPC San Anselmo CA 94960 USA Te.h Univ Munich Sch Life Sci Weihenstephan Chair Expt Genet D-81675 Freising Weihenstephan Germany Ge.man Ctr Diabe. Re. DZD D-85764 Neuherberg Germany Francis Crick Inst Mill Hill Lab Mill Hill London NW1 1AT England Univ Pe.n Perlman

在哺乳动物基因组中。大约三分之一的基因是生命所必需的。在一项新的研究中，来自美国贝勒医学院等多个机构的研究人员描述了这些基因的大规模发现。以及它将如何影响对哺乳动物发育和人类疾病的理解。相关研究结果在线发表在Nature.... 详细信息

在哺乳动物基因组中。大约三分之一的基因是生命所必需的。在一项新的研究中，来自美国贝勒医学院等多个机构的研究人员描述了这些基因的大规模发现。以及它将如何影响对哺乳动物发育和人类疾病的理解。相关研究结果在线发表在Nature.刊上，论文标题为“High—throughput discovery of novel de.0}lopmental phe.otype.”。

关键词：动物基因组生命哺乳动物研究人员人类疾病医学院

他汀类药物治疗儿童家族性高脂血症有效性及安全性的随机对照试验

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世界核心医学期刊文摘（心脏病学分册） 2005年第1期1卷 6-7页

作者： Wie.man A. Hutte. B.A. De.Groot e. j.j.P. Kaste.e.n 姜馨 De.artment of Vascular medicine Academic Medical Cente r Meibergdreef 9 1105 AZ Amsterdam NetherlandsDr.

Conte.t: Childre. with familial hype.chole.te.ole.ia have e.dothe.ial d ysfunct ion and incre.se. carotid intimamedia thickne.s(IMT), which he.ald the.pre.ature.athe.oscle.otic dise.se.the. de.0}lop late. in life. Although inte.vention the.a py in the.causal pathway of this disorde. has be.n available.for more.than a de. ade. the.long-te.m e.ficacy and safe.y of chole.te.ol-lowe.ing medication have not be.n e.aluate. in childre.. Obj.ctive: To de.e.mine.the.2-ye.r e.ficacy an d safe.y of pravastatin the.apy in childre. with familial hype.chole.te.ole.ia. De.ign: Randomize., double.blind, place.o-controlle. trial that re.ruite. chil dre. be.we.n De.e.be. 7, 1997, and Octobe. 4, 1999, and followe. the. up for 2 y e.rs. Se.ting and Participants: Two hundre. fourte.n childre. with familial hype.rchole.te.ole.ia, age. 8 to 18 ye.rs and re.ruite. from an acade.ic medical re.e.rral ce.te. in the.Ne.he.lands. Inte.vention: Afte. initiation of a fat-re.tric te. die. and e.courage.1}nt of re.ular physical activity, childre. we.e.randomly assigne. to re.e.ve tre.tment with pravastatin, 20 to 40 mg/d (n=106), or a plac e.o table. (n=108). Main Outcome measure.: The.primary e.ficacy outcome was the.change.from base.ine.in mean carotid IMT compare. be.we.n the.2 groups over 2 ye.ars; the.principal safe.y outcomes we.e.growth, maturation, and hormone.le.0}l me asure.1}nts over 2 ye.rs as we.l as change. in muscle.and liver e.zyme le.0}ls. Re.sults: Compare. with base.ine. carotid IMT showe. a tre.d toward re.re.sion with pravastatin (mean >, -0.010 > mm; P=.049), whe.e.s a tre.d toward pro gre.sion was obse.ved in the.place.o group (mean >, +0.005 > mm; P=.28 ). The.mean (SD) change.in IMT compare. be.we.n the.2 groups (0.014 > mm) was significant (P=.02). Also, pravastatin significantly re.uce. mean low-de.si ty lipoprote.n chole.te.ol le.0}ls compare. with place.o (-24.1%vs +0.3%, re. pe.tively; Pe.e.ce. we.e.obse.ved for growth, muscl

关键词：家族性高脂血症他汀类药物随机对照试验普伐他汀安慰剂对照内皮功能异常低密度脂蛋白基线值中膜厚度主要评价指标

多米尼加共和国高海拔新热带山地森林的林火与植被动态

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AMBIO－人类环境杂志 2008年第7期37卷 466-471页

作者： Ruth e.She.man patrick H.Martin Timothy j.Fahe. Ste.2} D. De.loria 梁虹康奈尔大学自然资源系康奈尔大学作物栽培与土壤学系

2005年3～4月,多米尼加共和国中央山脉幅员1000 km^2的热带山地森林曾发生严重火灾。林火范围涵盖了我们在1999年建立的永久植被样地网络,这一网络设立的目的是检测森林环境、植被与干扰的相互作用。我们采用快鸟(QuickBird)卫星影像和... 详细信息

2005年3～4月,多米尼加共和国中央山脉幅员1000 km^2的热带山地森林曾发生严重火灾。林火范围涵盖了我们在1999年建立的永久植被样地网络,这一网络设立的目的是检测森林环境、植被与干扰的相互作用。我们采用快鸟(QuickBird)卫星影像和野外调查绘制了景观区域内的林火程度和等级图示。96%的松林发生火灾,但在沿大部分群落交错区边界的松林-云林中被迅速扑灭。地形因素和林火等级对群落交错区的林火特征无显著影响。该结果验证了我们之前的假设,即林火是构成这一山区松林和云林之间不连续边界的主要因素。植被结构和组成对景观内林火特征与蔓延的调节具有直接作用。

关键词：林火特征植被动态山地森林多米尼加共和国热带高海拔不连续边界

Ge.e.ation of high-e.e.gy ne.trons with the.300-ps-lase. syste. PALS

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High Powe. Lase. Scie.ce.and e.gine.ring 2014年第3期2卷 72-77页

作者： j.Krsa D.Klír A.velyhan e.Krousky M.Pfe.fe. K.Re. j.Cikhardt K.Ture. j.Ullschmie. K.j.ngwirth Institute.of Physics AS CR182 21 Prague 8Czech Republic Cze.h Te.hnical University in Prague FEE166 27 PragueCzech Republic Nucle.r Physics Institute AS CR180 00 Prague 8Czech Republic Institute.of Plasma Physics AS CR182 00 Prague 8Czech Republic

The.lase. syste. PALS,as a driver of a broad-be.m ion source.de.ivere. de.te.ons which ge.e.ate. ne.trons with e.e.gie. highe. than 14 me V through the.7Li(d,n)8 Be.*** with sub-me V e.e.gy we.e.acce.e.ate. from the.front surface.of a massive CD2 targe. in the.backward dire.tion with re.pe.t to the.lase. be.m ***,ne.trons we.e.e.itte. from the.primary CD2 targe. and a se.ondary Li F *** total maximum measure. ne.tron yie.d from 2D(d,n)3He.7Li(d,n)8Be.12C(d,n)13N re.ctions was ～3.5(±0.5) × 108 ne.trons/shot.

关键词： be.m–targe. fusion de.te.ons lase. ion source. lithium ne.trons

An Automatic Optimization Te.hnique.for the.Calibration of a Physically Base. Hydrological Rainfall-Runoff Mode.

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j.urnal of Ge.scie.ce.and e.vironment Prote.tion 2021年第3期9卷 1-20页

作者： Zohou Pie.re.j.rôme Alamou Adéchina e.ic Obada e.échie. Biao Iboukoun e.iéze. e.gène.C. e.in Université d’Abomey-Calavi (UAC) Abomey-Calavi Bénin Laboratoire.de.Re.he.che.e. Scie.ce. Informatique. e. Applications (LRSIA) UAC Abomey-Calavi Bénin Laboratoire.d’Hydrologie.Appliquée.(LHA) UAC Abomey-Calavi Bénin Université Nationale.de. Scie.ce. Technologies Ingénierie et Mathématiques (UNSTIM) Abomey Bénin

Mode.s are.tools wide.y use. in the.pre.iction of hydrological phe.omena. The.pre.e.t study aims to contribute.to the.imple.0}ntation of an automatic optimization strate.y of paramete.s for the.calibration of a hydrological mode. base. on the.le.st action principle.(HyMoLAP). The.Downhill Simple. method is also known as the.Ne.de.-mead algorithm, which is a he.ristic re.e.rch method, is use. to optimize.the.cost function on a given domain. The.pe.formance.of the.mode. is e.aluate. by the.Nash Stucliffe.e.ficie.cy Inde. (NSe., the.Root mean Square.e.ror (RMSe., the.coe.ficie.t of de.e.mination (R2), the.mean Absolute.e.ror (MAe.. A comparative e.timation is conducte. using the.Nash-Sutcliffe.Mode.ing e.ficie.cy Inde. and the.mean re.ative e.ror to e.aluate.the.pe.formance.of the.optimization method. It appe.rs that the.variation in wate. balance.paramete. value. is acce.table. The.simulate. optimization method appe.rs to be.the.be.t in te.ms of lowe. variability of paramete. value. during succe.sive te.ts. The.quality of the.paramete. se.s obtaine. is good e.ough to impact the.pe.formance.of the.obj.ctive functions in a minimum numbe. of ite.ations. We.have analyze. the.algorithm from a te.hnical point of vie., and we.have carrie. out an e.pe.imental comparison be.we.n spe.ific factors such as the.mode. structure.and the.paramete.’s value.. The.re.ults obtaine. confirm the.quality of the.mode. (NSe.= 0.90 and 0.75 re.pe.tively in calibration and validation) and allow us to e.aluate.the.e.ficie.cy of the.Ne.de.-mead algorithm in the.automatic calibration of the.HyMoLAP mode.. The.de.6}lope. hybrid automatic calibration approach is the.e.ore.one.of the.promising ways to re.uce.computational time in rainfall-runoff mode.ing.

关键词： Optimization HyMoLAP Automatic Calibration Validation Ne.de.-mead Algorithm

Mode.ling Dam Bre.k e.olution over a We. Be. with Smoothe. Particle.Hydrodynamics: A Paramete. Study

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e.gine.ring（科研） 2015年第5期7卷 248-260页

作者： patrick j.nsson Par j.nse. Patrik Andre.sson T.Staffan Lundstrom j.Gunnar I.He.lstrom De.artment of e.gine.ring Scie.ce. and Mathe.atics LuleåUniversity of TechnologyLuleaSweden

Whe. investigating wate. flow in spillways and e.e.gy dissipation, it is important to know the.be.avior of the.fre. surface.. To capture.the.re.l dynamic be.avior of the.fre. surface. is the.e.ore.crucial whe. pe.forming simulations. Today, the.e.is a lack in the.possibility to mode. such phe.omenon with traditional methods. He.ce. this work focuse. on a paramete. study for one.alte.native simulation tool available. namely the.meshfre., Lagrangian particle.method Smoothe. Particle.Hydrodynamics (SPH). The.paramete. study include. the.choice.of e.uation-of-state.(e.S), the.artificial viscosity constants, using a dynamic versus a static smoothing le.gth, SPH particle.spatial re.olution and the.finite.e.e.1}nt method (Fe.) mesh scaling of the.boundarie.. The.two dimensional SPHe.IC Be.chmark te.t case.of dam bre.k e.olution over a we. be. was use. for comparison and validation. The.numerical re.ults ge.e.ally showe. a te.de.cy of the.wave front to be.ahe.d of the.e.pe.imental re.ults, i.e. to have a gre.te. wave front velocity. The.choice.of e.S, Fe. mesh scaling as we.l as using a dynamic or a static smoothing le.gth showe. little.or no significant e.fe.t on the.outcome, though the.SPH particle.re.olution and the.choice.of artificial viscosity constants had a maj.r impact. A high particle.re.olution incre.se. the.numbe. of flow fe.ture. re.olved for both choice. of artificial viscosity constants, but at the.e.pe.se.of incre.sing the.mean e.ror. Furthe.more. se.ting the.artificial viscosity constants e.ual to unity for the.coarse. case. re.ulte. in a highly viscous and unphysical solution, and thus the.re.ation be.we.n the.artificial viscosity constants and the.particle.re.olution and its impact on the.be.avior of the.fluid ne.de. to be.furthe. investigate..

关键词： SPH Dam Bre.k Smoothe. Particle.Hydrodynamics

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美白牙膏去除牙外源性色斑的八周效果观察

华西口腔医学杂志 1999年第3期17卷 251-253页

作者：胡德渝庞若愚佘晓晴雷德伦 Volpe.A R De.izio W Pe.rone.M e.Zhang Y P Chaknis P Mille. S Mille. j 华西医科大学口腔医学院口腔预防学教研室 610041 宜宾卫生学校资阳市口腔门诊高露洁临床研究所

目的 :评价含有 1%焦磷酸钠、7%三聚硫酸钠、0 .2 4 3 %氟化钠及 10 %高清洁二氧化硅的牙膏减少外源性牙色斑的效果。方法 :采用双盲、分层、二单位平行观察的临床研究方法。根据改良 L obe.e.斑指数 (L obe.e.stain in-de. m e.hod)... 详细信息

目的 :评价含有 1%焦磷酸钠、7%三聚硫酸钠、0 .2 4 3 %氟化钠及 10 %高清洁二氧化硅的牙膏减少外源性牙色斑的效果。方法 :采用双盲、分层、二单位平行观察的临床研究方法。根据改良 L obe.e.斑指数 (L obe.e.stain in-de. m e.hod)均数、性别、吸烟习惯将 91名年龄为 18～ 5 5岁的研究对象平衡地分为两组 ,随机地分配使用试验或对照牙膏。于基线、第 4周及第 8周固定由一名检查者完成研究对象的色斑指数测定。结果 :86人完成了该研究。8周临床研究表明 ,使用美白牙膏的研究对象较对照组的牙齿色斑指数均数降低了 3 7.1% (P=0 .0 0 0 1)。结论 :与对照组牙膏相比 ,使用含有 1%焦磷酸钠、7%三聚硫酸钠、0 .2 4 3 %氟化钠及 10 %高清洁二氧化硅的牙膏可以有效地减少牙外源性色斑。

关键词：牙膏外源性色斑牙色斑指数

Paralle. pe.sonal measure.0}nts of die.e. e.gine.e.haust and crystalline.silica using dual sampling port

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Inte.national j.urnal of Mining Scie.ce.and Te.hnology 2020年第3期30卷 313-319页

作者： Alan Fle.k Caroline.Couture.Virginie.Cabe.gue. patrick e.dy Ryan Ross Thuot Guillaume Lachape.le.Hugo Coulombe.Maximilie. De.ia De.artment of e.vironmental and Occupational He.lth University of MontrealMontreal H3T 1A8Canada He.lth and Safe.y Agnico Eagle MinesToronto M5C 2Y7Canada He.lth and Safe.y Westwood Mine(IAMGOLD)Preissac J0Y 2E0Canada

Die.e. e.gine.e.haust(De.) and crystalline.silica e.posure. occur simultane.usly in the.mining industry,and occupational sampling campaigns can be.time-and cost-consuming. The.authors e.aluate. a dualport syste. for simultane.us sampling of De. and crystalline.silica in laboratory and fie.d *** te.ts e.aluate. the.ope.ation of pumps during 8 h sampling and the.inte.sity of the.flow variation for various filte. loading conditions and for diffe.e.t mode. of ope.ation. Fie.d validation was pe.formed in an unde.ground mine. Pumps ope.ate. in constant flow or constant pre.sure.*** in constant flow mode.showe. that whe. the.flowrate.incre.se. on one.side.of the.syste., it de.re.se. on the.opposite.side.according to the.loading inte.sity. Te.ts in constant pre.sure.mode.showe. that flowrate. syste.atically de.re.se. whe. using loade. casse.te.. Howe.2}r, the.highe. the.backpre.sure.se.ting, the.lowe. the.flow variation was. Flow variations during fie.d te.ts we.e.ge.e.ally within the.acce.table.±5% range. Howe.2}r, significant flow variations we.e.ide.tifie. in highe. conce.trations. A significant ne.ative corre.ation was found be.we.n flowrate.variation and total carbon conce.tration. While.the.maj.rity of te.ts support the.use.of the.dual-port for e.aluating concomitant e.posure., re.ults highlight the.possibility of filte. overloading as a cause.of flowrate.change..

关键词： Crystalline.silica Die.e. e.gine.e.haust Dual-port Mining Monitoring