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Accuracy of combined PET/CT in image-guided interventions of liver lesions: An ex-vivo study

World Journal of Gastroenterology 2006年第15期12卷 2388-2393页

作者： patrick veit Christiane Kuehle Thomas Beyer Hilmar Kuehl Andreas Bockisch Gerald Antoch Department of Diagnostic and Interventional Radiology and Neuroradiology Department of Nuclear Medicine University Hospital Essen

AIM： Positioning of interventional devices in liver lesions is a challenging task if only CT is available. We investigated the potential benefit of combined PET/CT images for localization of interventional devices in interventional liver studies. METHODS： Thirty lesions each of hyperdense, isodense and hypodense attenuation compared to normal liver parenchyma were injected into 15 ex-vivo pig livers. All lesions were composed of the same amounts of gelatine containing 0.5 MBq of ^18F-FDG. Following lesion insertion, an interventional needle was placed in each lesion under CT-guidance solely. After that, a PET/CT study was performed. The localization of the needle within the lesion was assessed for CT alone and PET/CT and the root mean square （RMS） was calculated. Results were compared with macroscopic measurements after lesion dissection serving as the standard of reference. RESULTS： In hypo- and isodense lesions PET/CT proved more accurate in defining the position of the interventional device when compared with CT alone. The mean RMS for CT and PET/CT differed significantly in isodense and hypodense lesions. No significant difference was found for hyperdense lesions. CONCLUSION： Combined FDG-PET/CT imaging provides more accurate information than CT alone concerning the needle position in FDG-PET positive liver lesions. Therefore combined PET/CT might be potentially beneficial not only for localization of an interventional device, but may also be beneficial for guidance in interventional liver procedures.

关键词： Liver biopsy Radiofrequency ablation Combined PET/CT ex-vivo study Image guided interventions

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The clinical rehabilitation of spine and spinal cord disorders: detection and evaluation using SPECT/CT

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Neural Regeneration Research 2014年第8期9卷 795-797页

作者： Max J. Scheyerer Clément M.L.Werner patrick veit-Haibach Centre for Orthopaedic and Trauma Surgery University Medical CenterJosef-Stelzmann-Str.9CologneGermany Department of Surgery Division of TraumaSurgeryUniversity Hospital ZurichZurichSwitzerland Department of Medical Radiology Division of Nuclear MedicineUniversity Hospital ZurichZurichSwitzerland Department of Medical Radiology Diagnostic and Inverventional Radiolo-gyUniversity Hospital ZurichZurichSwitzerland

Spine-related disorders are caused by several factors including （1） spinal nerve/visceral nerve stimulation by perivertebral aseptic inflammation, （2） spinal nerve/visceral nerve compression by injured periverterbal soft tissue, dislocated perivertebral small joint, and proliferative/degenerative tissue and, （3） secondary damage to the spinal cord, peripheral nerve, vessels and autonomic nerve, which further stimulate nerve root sheath and surround- ing pain-carrying nerve fibers. In many cases, the source of pain cannot be detected by standard image modalities. Particularly in anatomically complex regions like the spine, SPECT/CT can be helpful for some aspects by intro- ducing a metabolical dimension to the classical way of morphology-based diagnostic. The aim of the present review was to give an overview of the adoption of SPECT/CT in a clinical spine-focused setting.

关键词： SPECT The clinical rehabilitation of spine and spinal cord disorders detection and evaluation using SPECT/CT

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Male Cone Evolution in Conifers:Not All That Simple

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American Journal of Plant Sciences 2014年第18期5卷 2842-2857页

作者： Christian Schulz Kristina Vanessa Klaus patrick Knopf Marcus Mundry veit Dorken Thomas Stutzel Evolution and Biodiversity of Plants Ruhr-Universitat BochumBochumGermany Botanischer Garten Rombergpark DortmundGermany Heisenberg Gymnasium DortmundGermany Fachbereich Biologie M 613 Universitat KonstanzKonstanzGermany

Despite the simple structure of male conifer cones, there is an enormous variability in cone properties observed upon more careful examination. The diversity ranges from simple cones to compound cones. Moreover, cones can be distinguished according to different spatial distributions on the tree. Simple cones are distributed either as solitary cones or as fascicular or clustered aggregations, while compound cones only exhibit fascicular or clustered aggregations. Here, we demonstrate that these different spatial distribution patterns correlate with distinct leaf types and variable branching frequencies. Furthermore, we provide new insights into the evolution of the sporangiophore, particularly in Taxaceae. Two notably important and fast-evolving characters of conifers are the number of sporangia per sporangiophore and the number of sporangiophores per cone. We demonstrate, across many species and types of cones, how these characters are able to adjust according to the optimal amount of pollen.

关键词： Pollen Cone Phylogeny Gymnosperms Compound Cone Microsporophyll

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肿瘤18F-FDG PET/MRI全身显像专家共识(德国)

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中华核医学与分子影像杂志 2020年第9期40卷 549-555页

作者：王洋洋杨光杰(译) 王振光(审校) Lale Umutlu Thomas Beyer Johannes Stefan Grueneisen Christoph Rischpler Harald H Quick veit-Haibach patrick Matthias Eiber Sandra Purz Gerald Antoch Sergios Gatidis Konstantin Nikolaou Jürgen FSchaefer IvoRausch Herrmann Ken K.Herrmann B.J.Krause S.O.Schoenberg L.Umutlu F.Anton G.Antoch M.Hacker M.Luster S.Neumann D.Vorwerk 青岛大学附属医院核医学科PET/CT中心 266100 Department of Diagnostic and Interventional Radiology and Neuroradiology University-Hospital EssenGermany QIMP Group Centre for Medical Imaging and Biomedical EngineeringMedical University of ViennaAustria Department of Nuclear Medicine University-Hospital EssenGermany High-Field-and Hybrid-MR-Imaging University-Hospital EssenGermany Joint Department of Medical Imaging University of TorontoCanada Department of Nuclear Medicine Klinikum rechts der IsarTechnical University of MunichGermany Department of Nuclear Medicine University of LeipzigGermany Department of Diagnostic and Interventional Radiology University DüsseldorfMedical FacultyDüsseldorfGermany Department of Diagnostic and Interventional Radiology University-Hospital TübingenGermany Department of Nuclear Medicine University Medical Center RostockGermany Department of Clinical Radiology and Nuclear Medicine University Medical Center MannheimGermany Deutsche Röntgengesellschaft BerlinGermany Division of Nuclear Medicine Department of Biomedical Imaging and Image-guided TherapyMedical University ViennaAustria Department of Nuclear Medicine University Hospital MarburgGermany Department of Radiology Klinikum IngolstadtGermany

PET/MRI一体机在2006年被首次提出可应用于临床;2010年,首台临床型PET/MRI一体机诞生。在20世纪早期,PET/CT和SPECT/CT一体机的广泛应用体现了融合显像的优势,为PET/MRI一体机的产生奠定了基础。目前,全球大约有150台全身PET/MRI一体机... 详细信息

PET/MRI一体机在2006年被首次提出可应用于临床;2010年,首台临床型PET/MRI一体机诞生。在20世纪早期,PET/CT和SPECT/CT一体机的广泛应用体现了融合显像的优势,为PET/MRI一体机的产生奠定了基础。目前,全球大约有150台全身PET/MRI一体机投入了临床应用,其中肿瘤显像是PET/MRI的主要应用领域之一。迄今为止,尽管PET/MRI临床应用在增加,但标准化的PET/MRI扫描方案还很少。因此,有必要制定患者检查和多中心研究都可遵循的标准化且一致性好的显像方案。该文总结了18F-脱氧葡萄糖(FDG)PET/MRI全身显像的患者就诊、检查准备、工作流程、显像方案以及报告书写等主要方面的专家共识,由长期使用PET、MRI和较早使用PET/MRI的相关资深专家制定。

关键词： PET/MRI 肿瘤全身显像专家共识

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