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A prolonged cholera outbreak caused by drinking contaminated stream water,Kyangwali refugee settlement,Hoima District,Western Uganda:2018

引用

Infectious Diseases of Poverty 2020年第6期9卷 107-108页

作者： Fred Monje Alex Riolexus Ario Angella Musewa Kenneth Bainomugisha Bernadette Basuta Mirembe Dativa Maria Aliddeki Daniel Eurien Godfrey Nsereko Carol Nanziri Esther Kisaakye Vivian Ntono Benon Kwesiga Daniel Kadobera Lilian Bulage Godfrey Bwire patrick Tusiime Julie Harris Bao-Ping Zhu Uganda Public Health Fellowship Program KampalaUganda 不详

Background: On 23 February 2018,the Uganda Ministry of Health(MOH)declared a cholera outbreak affecting more than 60 persons in Kyangwali Refugee Settlement,Hoima District,bordering the Democratic Republic of Congo(DRC).We investigated to determine the outbreak scope and risk factors for transmission,and recommend evidence-based control ***:: We defined a suspected case as sudden onset of watery diarrhoea in any person aged≥2 years in Hoima District,1 February–9 May 2018.A confirmed case was a suspected case with Vibrio cholerae cultured from a stool *** found cases by active community search and record reviews at Cholera Treatment *** calculated case-fatality rates(CFR)and attack rates(AR)by sub-county and *** a case-control study,we compared exposure factors among case-and *** estimated the association between the exposures and outcome using Mantel-Haenszel *** conducted an environmental assessment in the refugee settlement,including testing samples of stream water,tank water,and spring water for presence of fecal *** tested suspected cholera cases using cholera rapid diagnostic test(rdt)kits followed by culture for ***: We identified 2122 case-patients and 44 deaths(CFR=2.1%).Case-patients originating from Demographic Republic of Congo were the most affected(AR=15/1000).The overall attack rate in Hoima District was 3.2/1000,with Kyangwali sub-county being the most affected(AR=13/1000).The outbreak lasted 4 months,which was a multiple *** assessment showed that a stream separating two villages in Kyangwali Refugee Settlement was a site of open defecation for *** three water sources tested,only stream water was feacally-contaminated,yielding>100 CFU/100 *** 130 stool samples tested,124(95%)yielded *** by *** water was most strongly associated with illness(odds ratio[OR]=14.2,95%CI:1.5–133),although tank water also appeared to

关键词： Outbreak Cholera Refugees Uganda

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