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Enhancing pedestrian mobility in Smart Cities using Big Data

Journal of Management Analytics 2020年第2期7卷 173-188页

作者： Ebony Carter patrick adam Deon Tsakis Stephanie Shaw Richard Watson Peter Ryan Faculty of Business and Law Swinburne UniversityHawthornAustralia Swinburne University of Technology Defence Science&Technology Group MelbourneAustralia

Smart City is an emerging concept in global urban development.A Smart City applies ICT technologies to provide greater efficiencies for its urban areas and civilian *** of the key requirements for a Smart City is to exploit data from its ICT infrastructure(such as Internet of Things connected sensors)to improve city services and features such as accessibility and *** address this requirement,the City of Melbourne(COM)Smart City office maintains several hundred data sets relating to urban activity and *** datasets address parking,mobility,land use,3D data,statistics,environment,and major city developments such as rail *** promising dataset relates to pedestrian *** are obtained from sensors and updated on the COM website(City of Melbourne Open Data Platform:https://***/.)at regular *** data include the number of pedestrians passing 53 specific locations in the central business district and also their times and directions of *** a 24 h period,over 650,000 pedestrians were counted passing all *** rates of several thousand pedestrians per minute are regularly recorded during city rush hours at hotspots making the data amenable to Big Data analysis *** are obtained in graphical format as heatmaps and charts of city pedestrian traffic using both Microsoft Excel^(■)for static analysis and PowerBI^(■)for more advanced interactive visualisation and *** findings can identify pedestrian hotspots and inform future locations of traffic lights and street configurations to make the city more pedestrian ***,the experience gained can be used to examine other data sets such as bicycle traffic that can be analysed to inform city infrastructure *** work is suggested that could link these pedestrian flow data with social media data from smartphones and potentially wearable devices such as fitness monitors to correlate pedestrian s

关键词： Internet of Things Smart Cities Big Data analytics

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Human endogenous retrovirus type-W and multiple sclerosis–related smoldering neuroinflammation

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Neural Regeneration Research 2025年第3期20卷 813-814页

作者： Joel Gruchot Laura Reiche Andrew Chan Robert Hoepner patrick Küry Department of Neurology Medical Faculty and University Hospital DüsseldorfHeinrich Heine University DüsseldorfDüsseldorfGermany Department of Neurology InselspitalBern University Hospital and University of BernBernSwitzerland

Introduction to human endogenous retrovirus type-W(HERV-W): Genomic inheritance from the past includes retroviral sequences that have been stably incorporated into our genomes and account for up to 8% of human DNA.

关键词： endogenous inflammation Human

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Materials structure genealogy and high-throughput topological classification of surfaces and 2D materials

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npj Computational Materials 2018年第1期4卷 222-231页

作者： Lauri Himanen patrick Rinke adam Stuart Foster Department of Applied Physics Aalto UniversityP.O.Box 1110000076 AaltoEspooFinland Graduate School Materials Science in Mainz Staudinger Weg 9Mainz 55128Germany WPI Nano Life Science Institute(WPI-NanoLSI) Kanazawa UniversityKakuma-machiKanazawa 920-1192Japan

Automated and verifiable structural classification for atomistic structures is becoming necessary to cope with the vast amount of information stored in various computational materials *** we present a general recursive scheme for the structural classification of atomistic systems and introduce a structural materials map that can be used to organize the materials structure *** also introduce our implementation for the automatic classification of two-dimensional structures,especially focusing on surfaces and 2D *** classification procedure can automatically determine the dimensionality of a structure,further categorize the structure as a surface or a 2D material,return the underlying unit cell and also identify the outlier atoms,such as *** classification scheme does not require explicit search patterns and works even in the presence of defects and *** classification is tested on a wide variety of atomistic structures and provides a high-accuracy determination for all of the returned structural properties.A software implementation of the classification algorithm is freely available with an opensource license.

关键词： structure return becoming

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Reinforcement learning and A^(*)search for the unit commitment problem patrick de Mars^(∗),Aidan O’Sullivan

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Energy and AI 2022年第3期9卷 172-181页

作者： patrick de Mars Aidan O’Sullivan UCL Energy Institute United Kingdom

Previous research has combined model-free reinforcement learning with model-based tree search methodsto solve the unit commitment problem with stochastic demand and renewables generation. This approachwas limited to shallow search depths and suffered from significant variability in run time across probleminstances with varying complexity. To mitigate these issues, we extend this methodology to more advancedsearch algorithms based on A^(*) search. First, we develop a problem-specific heuristic based on priority list unitcommitment methods and apply this in Guided A^(*) search, reducing run time by up to 94% with negligibleimpact on operating costs. In addition, we address the run time variability issue by employing a novel anytimealgorithm, Guided IDA^(*), replacing the fixed search depth parameter with a time budget constraint. We showthat Guided IDA^(*) mitigates the run time variability of previous guided tree search algorithms and enablesfurther operating cost reductions of up to 1%.

关键词： Unit commitment Reinforcement learning Tree search Power systems

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Silk-based nerve guidance conduits with macroscopic holes modulate the vascularization of regenerating rat sciatic nerve

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Neural Regeneration Research 2025年第6期20卷 1789-1800页

作者： Carina Hromada patrick Heimel Markus Kerbl LászlóGál Sylvia Nürnberger Barbara Schaedl James Ferguson Nicole Swiadek Xavier Monforte Johannes C.Heinzel Antal Nógrádi Andreas H.Teuschl-Woller David Hercher Department Life Science Engineering University of Applied Sciences Technikum WienViennaAustria Austrian Cluster for Tissue Regeneration ViennaAustria Ludwig Boltzmann Institute for Traumatology The Research Center in Cooperation with AUVAViennaAustria University Clinic of Dentistry Medical University of ViennaViennaAustria Department of Plastic Reconstructive and Aesthetic SurgeryLandesklinikum Wiener Neustadt2700 Wiener NeustadtAustria Department of Anatomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary Medical University of Vienna Department of Orthopedics and Trauma SurgeryDevision of Trauma SurgeryViennaAustria Department of Hand- PlasticReconstructive and Burn SurgeryBG Unfallklinik TuebingenUniversity of TuebingenTuebingenGermany

Peripheral nerve injuries induce a severe motor and sensory deficit. Since the availability of autologous nerve transplants for nerve repair is very limited, alternative treatment strategies are sought, including the use of tubular nerve guidance conduits(tNGCs). However, the use of tNGCs results in poor functional recovery and central necrosis of the regenerating tissue, which limits their application to short nerve lesion defects(typically shorter than 3 cm). Given the importance of vascularization in nerve regeneration, we hypothesized that enabling the growth of blood vessels from the surrounding tissue into the regenerating nerve within the tNGC would help eliminate necrotic processes and lead to improved regeneration. In this study, we reported the application of macroscopic holes into the tubular walls of silk-based tNGCs and compared the various features of these improved silk^(+) tNGCs with the tubes without holes(silk^(–) tNGCs) and autologous nerve transplants in an 8-mm sciatic nerve defect in rats. Using a combination of micro-computed tomography and histological analyses, we were able to prove that the use of silk^(+) tNGCs induced the growth of blood vessels from the adjacent tissue to the intraluminal neovascular formation. A significantly higher number of blood vessels in the silk^(+) group was found compared with autologous nerve transplants and silk^(–), accompanied by improved axon regeneration at the distal coaptation point compared with the silk^(–) tNGCs at 7 weeks postoperatively. In the 15-mm(critical size) sciatic nerve defect model, we again observed a distinct ingrowth of blood vessels through the tubular walls of silk^(+) tNGCs, but without improved functional recovery at 12 weeks postoperatively. Our data proves that macroporous tNGCs increase the vascular supply of regenerating nerves and facilitate improved axonal regeneration in a short-defect model but not in a critical-size defect model. This study suggests that further optimizatio

关键词： axon regeneration blood vessel functional recovery macroporous nerve lesion peripheral nerve repair sciatic nerve silk-based nerve guidance conduit vascularization

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Effect of body mass index on functional outcome in primary total knee arthroplasty——a single institution analysis of 2180 primary total knee replacements

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World Journal of Orthopedics 2016年第10期7卷 664-669页

作者： Shane C O'Neill Joseph S Butler adam Daly Darren F Lui patrick Kenny Department of Orthopaedics Cappagh National Orthopaedic Hospital

AIM To evaluate the effect of body mass index(BMI) on short-term functional outcome and complications in primary total knee arthroplasty. METHODS All patients undergoing primary total knee arthroplasty at a single institution between 2007 and 2013 were identified from a prospective arthroplasty database. 2180 patients were included in the study. Age, gender, BMI, pre- and post-operative functional scores [Western Ontario and Mc Master University Arthritis Index(WOMAC) and SF-36], complications and revision rate were recorded. Patients were grouped according to the WHO BMI classification. The functional outcome of the normal weight cohort(BMI 0.05). Sub-group analysis revealed significantly worse WOMAC scores in class 2 obese 30.80 compared to overweight 25.80(P 25. Patients should not be denied total knee arthroplasty based solely on weight alone.

关键词： Total knee replacement Body mass index Total knee arthroplasty

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Streamlined CFD simulation framework to generate wind-pressure coefficients on building facades for airflow network simulations

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Building Simulation 2021年第4期14卷 1189-1200页

作者： Timur Dogan patrick Kastner Cornell University Department of ArchitectureEnvironmental Systems LaboratoryEast Sibley HallIthacaNY14850USA

Building energy modeling software generally comes with capable airflow network solvers for natural ventilation evaluation in multi-zone building energy models. These approaches rely on arrays of pressure coefficients representing different wind directions derived from simple box-shaped buildings without contextual obstructions. For urban or obstructed sites, or more complex building shapes, however, further evaluation is needed to avoid geometric oversimplification. In this study, we present an automated and easy-to-use simulation workflow for OpenFOAM-based exterior airflow simulations to generate arrays of pressure coefficients for arbitrary building shapes and contextual situations. The workflow is compared to other methods commonly used to obtain pressure coefficients for natural ventilation analysis. Finally, we assess for which climate zones and building types modelers should rely on more accurate CFD-based pressure coefficients and where it may be justifiable to rely on easier and readily available analytical approaches to determine pressure coefficients. Results suggest that existing workflows lead to significant error in predicted comfort hours for climates in the Global South and modelers should consider CFD-based facade pressure coeficients.

关键词： natural ventilation airflow networks EnergyPlus pressure coefficients computational fluid dynamics

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The dawn and rise of antimony use in the southern Caucasus

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Science China Earth Sciences 2022年第11期65卷 2037-2056页

作者： Sarah DILLIS patrick DEGRYSE Department of Earth and Environmental Sciences Katholieke Universiteit LeuvenCelestjnenlaan 200 EHeverlee 3001Belgium Faculty of Archaeology Leiden UniversityEinsteinweg 2Leiden 2333 CCThe Netherlands

Antimony(Sb)was utilised over several millennia as the prime material to opacify or decolour glass and glazes,as well as an accompanying element in copper(Cu)*** antimony objects are rare,and mostly confined to Chalcolithic Central Italy and to the first millennia BCE in the southern *** innovation of antimony use in metallurgy seems to be confined to the southern Caucasus,and the invention of it might be even more specifically situated in the Great *** knowledge of mining set the pathway for the initial stage of antimonial copper alloys in the first half of the third millennium BCE and for metallic antimony ornaments in the second half of the third millennium ***,the first major expansion of antimony in the metallurgy of the Racha-Lechkumi district in the southern Caucasus(present-day Georgia)started around 1700 BCE,while its spreading in glassmaking occurred in the Late Bronze Age(LBA).Explanations that place antimony adoption within its broader social context are favoured over those that consider material or geological properties in isolation.A recurring theme is the importance of comparative analysis,both geographically and between the different pyrotechnologies,including the precious metals and glass industries,to explore how social,political,climatic and economic conditions affected adoption and innovation *** these factors are considered to explain why the extraction of antimony blossomed in the Late Bronze Age in the southern Caucasus and to reconstruct a framework of exploitation,distribution/trade and use of antimony in the Caucasus and its neighbouring regions in the south and east.

关键词： Antimony Caucasus Metallurgy Glass Gold

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Optimal p-Ary Codes from One-Weight and Two-Weight Codes over IF_p+ vIF_p

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Journal of Systems Science & Complexity 2015年第3期28卷 679-690页

作者： SHI Minjia SOL patrick School of Mathematical Sciences Anhui University Telecom Paris Tech

This paper is devoted to determining the structures and properties of one-Lee weight codes and two-Lee weight projective codes Ck1,k2,k3 over p IF+ v IFp with type p2k1pk2pk3. The authors introduce a distance-preserving Gray map from( IFp + v IFp)nto2np. By the Gray map, the authors construct a family of optimal one-Hamming weight p-ary linear codes from one-Lee weight codes over IFp+ v IFp, which attain the Plotkin bound and the Griesmer bound. The authors also obtain a class of optimal p-ary linear codes from two-Lee weight projective codes over IFp + vIFp, which meet the Griesmer bound.

关键词： Generator matrix Gray map linear code one-Lee weight code two-Lee weight code.

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Revisiting the dissolution of biogenic Si in marine sediments： a key term in the ocean Si budget

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Acta Geochimica 2017年第3期36卷 429-432页

作者： patrick Frings Department of Geoscience Swedish Museum of Natural History 10405 Stockholm Sweden Earth Surface Geochemistry GFZ German Research Centre for Geosciences 14473 Telegrafenberg Potsdam Germany

Of the　~240*10^(12)mol year^(-1)of biogenic silica(bSi)produced by diatoms and other silicifying organisms,only roughly 3%–4%escapes dissolution to be permanently *** the global scale,how,where and why b Si is preserved in sediment is not well *** help address this,I compile 6245 porewater dissolved Si concentrations from 453 sediment cores,to derive the concentration gradient at the sediment–water interface and thus diffusive fluxes out of the *** range from\0.002 to 3.4 mol m^(-2)year^(-1),and are independent of temperature,depth and *** classified by sediment lithology,predominantly siliceous sediments unsurprisingly have higher mean diffusive fluxes than predominantly calcareous or clay-rich *** with the areal extent of these lithologies,the‘best-guess’global sedimentary b Si recycling flux is69 9 10^(12)mol year^(-1).

关键词： Biogenic silica Diatoms Ocean Si cycle Dissolution

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