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Trends of autoimmune liver disease inpatient hospitalization and mortality from 2011 to 2017:A United States nationwide analysis

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World Journal of Hepatology 2024年第7期16卷 1029-1038页

作者： Ali Wakil Yasameen Muzahim Mina Awadallah Vikash Kumar Natale Mazzaferro patricia Greenberg Nikolaos Pyrsopoulos department of Gastroenterology and Hepatology The Brooklyn Hospital CenterBrooklynNY 11201United States department of Gastroenterology and Hepatology University of Iowa Hospitals and ClinicsIowa CityIA 52242United States department of Gastroenterology and Hepatology Rutgers the New Jersey Medical SchoolNewarkNJ 07103United States department of Biostatistics and Epidemiology Rutgers School of Public HealthPiscatawayNJ 08854United States

BACKGROUNd Autoimmune liver diseases(AiLd)encompass a variety of disorders that target either the liver cells(autoimmune hepatitis,AIH)or the bile ducts[primary biliary cholangitis(PBC),and primary sclerosing cholangitis(PSC)].These conditions can progress to chronic liver disease(CLd),which is characterized by fibrosis,cirrhosis,and hepatocellular *** studies have indicated a rise in hospitalizations and associated costs for CLd in the US,but information regarding inpatient admissions specifically for AiLd remains *** To examine the trends and mortality of inpatient hospitalization of AiLd from 2011 to *** This study is a retrospective analysis utilizing the National Inpatient Sample(NIS)*** subjects admitted between 2011 and 2017 with a diagnosis of AiLd(AIH,PBC,PSC)were identified using the International Classification of diseases(ICd-9)and ICd-10 *** AiLd admission was defined if the first admission code was one of the AiLd *** AiLd admission was defined as having the AiLd diagnosis anywhere in the admission diagnosis(25 diagnoses).Subjects aged 21 years and older were *** national estimates of hospitalization were derived using sample weights provided by NIS.χ^(2)tests for categorical data were *** primary trend characteristics were in-hospital mortality,hospital charges,and length of *** From 2011 to 2017,hospitalization rates witnessed a significant decline,dropping from 83263 admissions to 74850 admissions(Pd were predominantly elderly(median 53%for age>65),mostly female(median 59%)(Pd primarily Caucasians(median 68%)(Pdicare was the major insurance(median 56%),followed by private payer(median 27%)(Pdistribution for these admissions(median 33%)(Pdmissions taking place in big teaching institutions(median 63%)(Pdmissions rose from 66031 in 2011

关键词： Autoimmune hepatitis Autoimmune liver disease Epidemiology Cost-Effective care Admissions trend Mortality rate

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Item-Level Analysis of the Revised Occupational Therapy Fieldwork Performance Evaluation Applied in Practice

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Open Journal of Therapy and Rehabilitation 2024年第2期12卷 145-159页

作者： Cynthia L. Sears Brad E. Egan patricia F. Tomsic Craig A. Velozo Graduate College of Health Professions Occupational Therapy Program Hawai&#8217i Pacific University Honolulu HI USA College of Science and Health Occupational Therapy Program DePaul University Chicago IL USA department of Occupational Therapy Wingate University Wingate NC USA College of Health Professions Department of Rehabilitation Sciences Division of Occupational Therapy Medical University of South Carolina Charleston SC USA

Competency-based assessments for healthcare professionals are critical for safe and effective client outcomes. Rehabilitation clinical skill competency assessments must be validated and revised to produce safe and skilled practitioners. The revised American Occupational Therapy Association (AOTA) Fieldwork Performance Evaluation (FWPE) instrument measures occupational therapy student performance to determine readiness for practice. The assessment includes thirty-seven competencies that address both profession specific clinical skills and general professional behavior skills. The objective of this study was to use Rasch methods to explore the use of the revised FWPE in actual fieldwork practice and to determine the instrument’s psychometric properties when separating the item components into two distinct subdomains: General Health Professions Competences and Occupational Therapy-Specific Competencies. Internal construct validity and test reliability were analyzed using data from 149 occupational therapy students after completing their initial Level II A fieldwork clinical internship. This study examined the item difficulty hierarchy, item fit, person-fit to model, person separation index, person separation reliability coefficient, strata, ceiling and floor effect, and unidimensionality of the FWPE instrument as a whole and as two separate domains. With the exception of not meeting the criteria for unidimensionality, the full FWPE instrument and the Occupational Therapy-Specific Competencies subdomain showed acceptable item-level psychometrics for reliability and precision. While the General Health Professions Competencies subdomain showed good item-level psychometrics, it was below the criterion for reliability and only separated the sample into two strata. Results support the validity, reliability, and clinical use of the revised FWPE full instrument and the Occupational Therapy-Specific Competencies subdomain to measure entry-level clinical skill competencies in pr

关键词： Rehabilitation Competency-Based Assessments Occupational Therapy Measurement Rasch Analysis

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Comparative Study of Early Neonatal Complications between the First and Second Twin during Twin Vaginal deliveries at the Yaounde Gynaeco-Obstetric and Pediatric Hospital, and the Yaounde Central Hospital

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Open Journal of Obstetrics and Gynecology 2024年第3期14卷 381-392页

作者： Florent Ymele Fouelifack Felicite Nguefack patricia Bashir Kadidja Roosvelt dongmo Tiodjou Jeanne Hortence Fouedjio Pascal Foumane Higher Institute of Medical Technology of Nkolondom Yaounde Cameroon Obstetrics and Gynaecology Unit of Yaounde Central Hospital Yaounde Cameroon Associative Group for Research Education and Health La Falaise “GARES-Falaise” Dschang Cameroon Obstetrics and Gynaecology Unit of the Yaounde Gynaeco-Obstetrics and Pediatric Hospital Yaounde Cameroon Faculty of Medicine and Biomedical Sciences University of Yaounde I Yaounde Cameroon

Introduction: Twin birth is the expulsion of two fetuses and their appendages out of the woman’s reproductive tract. It’s a high-risk delivery because of the high frequency of maternal, fetal and neonatal complications. Few studies exist on the comparative prognoses of twins. Our objective was to compare early neonatal complications in first and second twins. Methods: We carried out a cross-sectional prospective study from January 2 to April 30, 2020 (4 months) at the Yaounde Gynaeco-Obstetric and Pediatric Hospital, and the Yaounde Central Hospital. data collected were analyzed using IBM SPSS version 23. descriptive statistics were done in frequencies and percentages, means and standard deviations. Paired-sample student's t-test were used to compare means. McNemar’s Chi-square and Ficher’s exact tests were used to compare proportions. Statistical significance was set at p-values less than 0.05. Results: Of a total of 2183 deliveries during the study period, 43 (1.96%) were twin vaginal deliveries. Among the 43 women, 41 consented to have their newborns participate in the study. Overall, APGAR scores were better for the first twins at the first (p = 0.004) and fifth (p = 0.031) minutes than for the second twins. Although both twins had complications and that there were 4 neonatal deads of the second twin, there was no relationship between studied complications and the rank of the twin (p = 0.310). Conclusion: As the APGAR score seemed to be better for first twins, clinicians should pay more attention during twin births, in order to improve the prognosis of the second twin.

关键词： Comparison Vaginal Birth Rank of Twin Early Neonatal Complications

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Automatic detection and Characterization of Human Veins Using Infra-Red Image Processing

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Journal of Computer and Communications 2024年第9期12卷 141-159页

作者： Jean Ndoumbe Brice Ekobo Akoa Gaelle patricia Talotsing Frederic Franck Kounga Samuel Kaissassou Bertin Chouanmo Njo Laboratory of Computer Engineering Data Science and Artificial Intelligence Department of Computer & Telecommunications Engineering National Higher Polytechnic School Douala Cameroon Laboratory of Electrical Engineering Mechatronics and Signal Processing Department of Electrical & Telecommunications Engineering National Advanced School of Engineering Yaound Cameroon Mobile Computing and Networking Research Laboratory Department of Computer and Software Engineering Polytechnique Montreal Montreal Canada digiPlus SARL Bonamoussadi Douala Cameroon

The detection and characterization of human veins using infrared (IR) image processing have gained significant attention due to its potential applications in biometric identification, medical diagnostics, and vein-based authentication systems. This paper presents a low-cost approach for automatic detection and characterization of human veins from IR images. The proposed method uses image processing techniques including segmentation, feature extraction, and, pattern recognition algorithms. Initially, the IR images are preprocessed to enhance vein structures and reduce noise. Subsequently, a CLAHE algorithm is employed to extract vein regions based on their unique IR absorption properties. Features such as vein thickness, orientation, and branching patterns are extracted using mathematical morphology and directional filters. Finally, a classification framework is implemented to categorize veins and distinguish them from surrounding tissues or artifacts. A setup based on Raspberry Pi was used. Experimental results of IR images demonstrate the effectiveness and robustness of the proposed approach in accurately detecting and characterizing human. The developed system shows promising for integration into applications requiring reliable and secure identification based on vein patterns. Our work provides an effective and low-cost solution for nursing staff in low and middle-income countries to perform a safe and accurate venipuncture.

关键词： Vein detection Blood Radiation Infrared Image CLAHE Algorithm Raspberry Pi

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Phagocytosis: A Practical Approach for Evaluating Neutrophil Function in Health and disease

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Modern Research in Inflammation 2024年第2期13卷 9-28页

作者： Oscar Rojas-Espinosa patricia Arce-Paredes Sergio Islas-Trujillo Luis Enrique Becerril-Villanueva María dolores Ponce-Regalado departamento de Inmunologa Escuela Nacional de Ciencias Biolgicas Instituto Politcnico Nacional Ciudad de Mxico Mxico Laboratorio de Psicoinmunologa Instituto Nacional de Psiquiatra Ramn de la Fuente Ciudad de Mxico Mxico departamento de Ciencias de la Salud Centro Universitario de los Altos Universidad de Guadalajara Jalisco Mxico

Neutrophils, crucial players in the effector phase of the immune response, are recognized as important mediators of both innate and adaptive immune responses. Through the production of pro- and anti-inflammatory cytokines, they modulate the function of T and other lymphoid cells. Countless reports have highlighted the importance of these cells as efficient antimicrobial agents and annotated their involvement in the pathology of infectious and noninfectious diseases. The development of modern, sophisticated technologies has allowed the study of the functions of these cells in clinical settings. These advanced technologies include fluorescence-activated cell sorters, confocal microscopy, automated cell image analyzers, and live cell analysis instruments. Unfortunately, the cost of these modern instruments, maintenance, reagents, and the need for qualified technicians prohibit their use in low-income laboratories and universities in developing countries. With this in mind, we propose a series of basic tests that can be used in low-input clinical laboratories and universities to evaluate the function of neutrophils in health and disease. Our methodology allows us to assess in a practical and low-cost manner the functions of neutrophils in the phagocytic process, including opsonization, ingestion, ROI production (NBT reduction), myeloperoxidase content, phagosome-lysosome fusion, microbicidal activity, and NET production. Thus, under a disadvantageous ambiance, this may guide physicians in deciding whether a patient’s illness involves phagocytic defects without imposing a heavy financial *** Abstract[-rId13-]

关键词： Phagocytosis Neutrophils Microbicidal Activity Netosis

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明智地利用时间

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中学生英语 2024年第3期 10-11页

作者： patricia Ruhaak 肖雅琪(译) 不详

“你在干什么?”当我弓着腰坐在课桌边上时,我五年级的老师问道。“我正在收拾背包。几分钟后铃声就要响了。”

关键词：五年级老师干什么

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Vanadium mineralization at Los Chihuidos sediment-hosted Cu-V deposit,Neuquén Basin,Argentina:An approach to vanadium ore forming processes

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Geoscience Frontiers 2024年第1期15卷 225-246页

作者： Ana L.Rainoldi daniel Beaufort Marta B.Franchini Adolfo Giusiano Sabine Petit patricia Patrier M.Josefina Pons dpto.de Geología Universidad Nacional del Sur(UNS)8000 Bahía BlancaArgentina Consejo Nacional de Investigaciones Científicas y Técnicas Centro Patagónico de Estudios MetalogenéticosArgentina Universitéde Poitiers IC2MPCNRS-UMR 7285HydrasaF-86022 Poitiers CedexFrance Universidad Nacional del Comahue Facultad de IngenieríaDepartamento de Geología y Petróleo8300 NeuquénArgentina Consultant Geologist 8300 NeuquénArgentina Universidad Nacional de Río Negro Instituto de Investigación en Paleobiología y GeologíaRío NegroArgentina

Vanadium mineralization at Los Chihuidos deposit of the Neuquén Basin is linked to the development of a redox front system related to the inflow of hydrocarbons into the red sandstone of the Huincul *** of hydrocarbons with oxidized red beds and connate water generated redox reactions where hematite was dissolved due to iron reduction resulting in the discoloration of the red *** the contact between oxidized red sandstone and reduced white sandstone,precipitation of specific mineral phases resulted in the V ore with minor amounts of *** the implementation of the redox interface,abundant V-montmorillonite and V-hematite precipitated at the more oxidizing conditions and Cu-V-corrensite-type at the more reducing conditions of the redox *** the redox front advanced with fluids constantly migrating into the reservoir,more reducing conditions were stablished,promoting chloritization and minor illitization with V-Cu incorporation and continuous upgrading of the *** ore mineralogy consists of clay minerals including V-bearing montmorillonite,Cu-V-corrensite-type,V-di-trioctahedral chlorite and Cu-tri-trioctahedral chlorite with minor V-illite-smectite mixed-layer minerals and associated secondary *** over illitization was favored due to high amounts of Fe and Mg in detrital clasts and in connate fluids and by low K availability related to low amounts of detrital *** spatial transition of V and/or Cu bearing clay minerals observed through the mineralized redox front at Los Chihuidos deposit(kaolinite→smectite→illite/smectite→corrensite-type→di-trioctahedral-chlorite→tri-trioctahedral-chlorite)and the related variation of V-Cu concentrations in bulk rock are indicative of increasing pH and decreasing Eh of resident solutions from red to white sandstones during the hypogene mineralization *** influx of Cu-rich oxidized basinal brines precipitated main copper ore with Cu-sulfides in the white sandst

关键词： Clay minerals V-chlorite Redox front Bleaching Hydrocarbons

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Metabolic disease and the liver: A review

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World Journal of Hepatology 2024年第1期16卷 33-40页

作者： Márcia Vargas Sheila de Castro Cardoso Toniasso patricia G Riedel Camila Pereira Baldin Francielle Lopes dos Reis Robson Martins Pereira Maria Carlota Borba Brum dvora Joveleviths Mario Reis Alvares-da-Silva Program of Graduate Science in Gastroenterology and Hepatology Federal University of Rio Grande do SulPorto Alegre 90040-060Rio Grande do SulBrazil School of Medicine Federal University of Rio Grande do SulPorto Alegre 90040-060Brazil Program of Graduate Science in Gastroenterology and Hepatology Clinicas Hospital of Porto AlegrePorto Alegre 90410000Brazil Medicine Faculty Federal University of Rio Grande do Sul Federal University of Rio Grande do SulPorto Alegre 90040-060Brazil division of Gastroenterology and Hepatology Clinicas Hospital of Porto AlegrePorto Alegre 90035007Brazil

Metabolic dysfunction-associated steatotic liver disease(MASLd)is the most common liver disease worldwide,with an estimated prevalence of 31%in Latin *** presence of metabolic comorbidities coexisting with liver disease varies substantially among *** is acknowledged that obesity is boosting the type 2 diabetes mellitus“epidemic,”and both conditions are significant contributors to the increasing number of patients with *** steatohepatitis represents a condition of chronic liver inflammation and is considered the most severe form of *** diagnosis is based on the presence of steatosis,noninvasive scores and altered liver *** scores of liver fibrosis,such as serum biomarkers,which should be used in primary care to rule out advanced fibrosis,are simple,inexpensive,and widely ***,guidelines from international hepatology societies recommend using noninvasive strategies to simplify case finding and management of high-risk patients with MASLd in clinical ***,there is no definite pharmacological treatment for the *** public health policies to treat patients with risk factors for MASLd prevention is essential.

关键词： Nonalcoholic fatty liver disease Primary care Metabolic risk Liver Metabolism

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Root Sprouts of domesticated Phaseolus coccineus L. Overwinter Plants and the Environment at Its Collection Sites

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Open Journal of Ecology 2024年第5期14卷 508-521页

作者： Ma. Luisa patricia Vargas-Vázquez Jorge Alberto Acosta-Gallegos Fabián Islas-Gutiérrez Enrique Buendía-Rodríguez Campo Experimental Valle de Mé xico Instituto Nacional de Investigaciones Forestales Agr&#237colas y Pecuarias Texcoco Mexico Campo Experimental Bají o Instituto Nacional de Investigaciones Forestales Agr&#237colas y Pecuarias Guanajuato M&#233xico

Buds emerge from the roots of domesticated runner bean plants (Phaseolus coccineus L.) as sprouts and give the crop its persistence. This particularity of the species seems to be associated with the environment where the species was cultivated during long time. data on regrowth traits were recorded on 70 accessions of domesticated P. coccineus after overwintering at a site in the central highlands of Mexico. The characteristics recorded included fresh weight of vegetative regrowth, root length, root crown diameter, and diameter of the main root. Most accessions that sprout the following spring, after the grain harvest of the previous year, come from temperate and semi-cold sites with cambisol and andosol soils in mixed Quercus pine forest and high mountain fir trees. Those that do not sprout are from sites of semiarid temperate climate, haplic phaeozem soil in shrub grasslands with deciduous broadleaved trees, and semiwarm subhumid climate, eutrophic regosol soil in deciduous broadleaved forest. Two types of roots were differentiated: branched and thickened taproots, also associated with a different climate, and the type of soil of the collection sites.

关键词： P. coccineus distribution Vegetation-Environment Interactions drought-Alternative Species Root-Regrowth

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Assessement of Nutritional Status of Households Using Weighed Food Intake in North West Region of Cameroon

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Food and Nutrition Sciences 2024年第1期15卷 1-26页

作者： Ebai Nee Besong patricia Ange Gustave Mabiama Eyenga Manga Nyangono Biyegue Fernande C. Winifred Fila Ogah Eridiong O Onyenweaku University of douala Higher Teacher Training College For Technical Education Douala Cameroon department of Biochemistry Faculty of Basic Medical Science University of Calabar Calabar Nigeria

This study determined the nutritional status of households in North western region of Cameroon using weighed food intake. Twenty–two rural and 106 urban households were randomly selected for weighed food intake descriptive and inferential statistics were used to analyze collected data and significance at p d. Corn fufu with huckleberry was the most frequently consumed meal with little or no animal-source protein. Protein and B group vitamins intake of respondents in both communities were below the FAO/WHO recommended values while energy, iron, and vitamins A and C were in excess for most age groups. Adolescents 10 - 19 years and adults 20 years and above failed to meet at least 85% of RNI for calcium.

关键词： Food Intake Household Nutrients Nutritional Status

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