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Diversity of Emergency Codes in Hospitals

International Journal of Clinical Medicine 2013年第11期4卷 499-503页

作者： Nilsa Padilla-Elias Marisol Pena-Orellana Ralph Rivera-Gutierrez Juan AGonzalez-Sanchez Heriberto AMarin Centeno Hector Alonso-Serra Liza Millan-Perez patricia monserrrate-vazquez (Center for Public Health Preparedness)Graduate School of Public Health Medical Sciences CampusUniversity of Puerto RicoSan JuanPuerto Rico (School of Medicine)Department of Emergency Medicine Medical Sciences CampusUniversity of Puerto RicoSan JuanPuerto Rico Department of Health Services Administration Graduate School of Public HealthMedical Sciences CampusUniversity of Puerto RicoSan JuanPuerto Rico

Background: Hospitals must be prepared to deal efficiently and effectively with different emergencies. To accomplish this, several countries have standardized their hospital emergency codes to improve their response capability. This is particularly important in Puerto Rico given that many health professionals, particularly physicians and nurses, provide services in more than one hospital. This study examined the emergency codes and alerts utilized in Puerto Rican hospitals. Objective: To assess hospitals’ level of emergency preparedness and response capability related to the variability of emergency codes and alerts utilized to respond to a situation in Puerto Rico. Method: A survey was conducted to characterize hospital emergency department level of preparedness and response to a mass fatality incident. A total of 39 out of a sample of 44 hospitals participated in the study. Semi-structured questionnaires were administered by the research team to members of each hospital’s administrative staff to explore the following: general hospital characteristics, emergency plans, emergency department capacity, collaborative agreements, personnel training, emergency communications, laboratory facilities, treatment protocols, security, epidemiologic surveillance, equipment and infrastructure. Results: Some hospitals in Puerto Rico use color coded emergency alerts, while others use key words or codes. Single color emergency codes can have different meanings in different hospitals. Conclusions: The findings clearly show that there is a lack of uniformity and clarity in the emergency codes utilized by hospitals in Puerto Rico. Single color codes have diverse meanings in different hospitals. This could adversely affect hospitals’ efficient and effective emergency response.

关键词： Communications Hospitals Health Health Communications Emergency Preparedness Preparedness Emergency Codes

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Treating amyotrophic lateral sclerosis with allogeneic Schwann cell-derived exosomal vesicles: a case report

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Neural Regeneration Research 2025年第4期20卷 1207-1216页

作者： Pascal J.Goldschmidt-Clermont Aisha Khan George Jimsheleishvili patricia Graham Adriana Brooks Risset Silvera Alexander J.P.Goldschmidt Damien D.Pearse W.Dalton Dietrich Allan D.Levi James D.Guest Miller School of Medicine University of MiamiMiamiFLUSA Stem Cell Institute Miller School of MedicineUniversity of MiamiMiamiFLUSA The Miami Project to Cure Paralysis Miller School of MedicineUniversity of MiamiMiamiFLUSA Alzady International LLC MiamiFLUSA Neurological Surgery Miller School of MedicineUniversity of MiamiMiamiFLUSA

Schwann cells are essential for the maintenance and function of motor neurons,axonal networks,and the neuromuscular *** amyotrophic lateral sclerosis,where motor neuron function is progressively lost,Schwann cell function may also be ***,important signaling and potential trophic activities of Schwann cell-derived exosomal vesicles have been *** case report describes the treatment of a patient with advanced amyotrophic lateral sclerosis using serial intravenous infusions of allogeneic Schwann cell-derived exosomal vesicles,marking,to our knowledge,the first instance of such *** 81-year-old male patient presented with a 1.5-year history of rapidly progressive amyotrophic lateral *** initial diagnosis,the patient underwent a combination of generic riluzole,sodium phenylbutyrate for the treatment of amyotrophic lateral sclerosis,and *** patient volunteered to participate in an FDA-approved single-patient expanded access treatment and received weekly intravenous infusions of allogeneic Schwann cell-derived exosomal vesicles to potentially restore impaired Schwann cell and motor neuron *** confirmed that cultured Schwann cells obtained from the amyotrophic lateral sclerosis patient via sural nerve biopsy appeared impaired(senescent)and that exposure of the patient’s Schwann cells to allogeneic Schwann cell-derived exosomal vesicles,cultured expanded from a cadaver donor improved their growth capacity in *** a period of observation lasting 10 weeks,during which amyotrophic lateral sclerosis Functional Rating Scale-Revised and pulmonary function were regularly monitored,the patient received weekly consecutive infusions of 1.54×1012(×2),and then consecutive infusions of 7.5×1012(×6)allogeneic Schwann cell-derived exosomal vesicles diluted in 40 mL of Dulbecco’s phosphate-buffered *** of the infusions were associated with adverse events such as infusion reactions(allergic or otherwise)or

关键词： allogeneic amyotrophic lateral sclerosis exosomes infusion neuromuscular junction Schwann cell

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Surfactant-free synthesis of metallic bismuth spheres by microwave-assisted solvothermal approach as a function of the power level

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Frontiers of Materials Science 2016年第4期10卷 394-404页

作者： Miriam ESTRADA FLORES patricia SANTIAGO JACINTO Carmen M. REZA SAN GERMAN Luis RENDON vazquez Raul BORJA URBY Nicolas CAYETANO CASTRO Instituto de Investigaciones en Materiales Circuito Exterior S/N Zona de Institutos Ciudad Universitaria C.P. 04510 Mexico D.F. Mexico Instituto de Fisica Circuito de la Investigaci6n Cientffica Edificio Marcos MoshinskyLaboratorio de Materiales Nanoestructurados Ciudad Universitaria C.P. 04510 Mexico D.F. Mexico Escuela Superior de Ingenierfa Qufmica e Industrias Extractivas Unidad Profesional Adolfo L6pez Mateos Edif. Z-5 2do. Piso Instituto Politecnico Nacional C.P. 07738 Mexico D.F. Mexico Centro de Nanociencias y Micro y Nanotecnologfas. Instituto Politecnico Nacional Av. Luis Enrique Erro S/NUnidad Profesional Adolfo Lopez Mateos Zacatenco Delegaci6n Gustavo A. Madero C.P. 07738 Mexico D.F. Mexico

In the present work, the synthesis of micro- and nano-sized spheres of metallic bismuth by microwave-assisted solvothermal method is reported. The synthesis method was carried out at different power levels and at a unique frequency of microwave irradiation. The sphere sizes were controlled by the microwave power level and the concentration of dissolved precursor. Structural and morphological characterization was performed by SEM, HRTEM, EELS and XRD. The results demonstrated that rhombohedral zero valent Bi spheres were synthesized after microwave radiation at 600 and 1200 W. However, if the power level is decreased to 120 W, a monoclinic phase of Bi203 is obtained with a flake-like morphology. In comparison with a conventional hydrothermal process, the microwave-assisted solvothermal approach provides many advantages such as shorter reaction time, optimum manipulation of morphologies and provides a specific chemical phase and avoids the mixture of structural phases and morphologies which is essential for further applications such as drug delivery or functionalization with organic materials, thanks to its biocompatibility.

关键词： microwave oven power level metallic bismuth spherical structures mechanism of formation electron energy loss spectroscopy (EELS)

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Textural and geochemical characteristics of late Pleistocene to Holocene fine-grained deep-sea sediment cores(GM6 and GM7),recovered from southwestern Gulf of Mexico

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Journal of Palaeogeography 2018年第3期7卷 253-271页

作者： Abigail Anaya-Gregorio John S.Armstrong-Altrin Marfa Luisa Machain-Castillo patricia C.Montiel-Garcia Mayla A.Ramos-vazquez Licenciatura en Ingenieria en Geologia Ambiental Area Academica de Ciencias de la Tierra y MaterialesUniversidad Autonoma del Estado de HidalgoMineral de la ReformaHidalgoMexico. Instituto de Ciencias del Mary Limnologia Universidad Nacional Autenoma de MexicoUnidad de Procesos Oceanicos y CosterosCiudad Universitaria04510 Ciudad de MexicoMexico. Area Academica de Ciencias de la Tierra y Materiales Universidad Autonoma del Estado de HidalgoCiudad UniversitariaCarretera Pachuca-Tulancingo Km 4.5Col.CarbonerasC.P.42184 Mineral de la ReformaHidalgoMexico. Posgrado en Ciencias del Mary Limnologia Universidad Nacional Autonoma de MexicoCiudad Universitaria3000CoyoacanC.P.04510 Ciudad de MexicoMexico.

Texture, mineralogy, geochemistry, and 14C ages of two deep-sea sediment cores （GM6 and GM7） recovered in the southwestern Gulf of Mexico were investigated to infer their provenance and depositional condition. The sediments are enriched in fine-grained silt and clay and poor in sand content. Mineralogically, the sediments consist of quartz, calcite, smectite, and kaolinite. Based on the ]4C data, the age of the GM6 and GM7 sediment cores were calculated as 23,615 cal yrs. BP and 19,007 cal yrs. BP, respectively. The weathering indices such as chemical index of alteration （CIA）, chemical index of weathering （CIW）, and plagioclase index of alteration （PIA） in GM6 （56-69, 60-74, and 6]-73, respectively） and GM7 （54-69, 57-76, and 55-74, respectively） cores revealed a moderate-to-high intensity of weathering. The rare earth element （REE） patterns suggested that the sediments were derived mostly by the weathering of intermediate rocks, exposed along the coastal regions of the Gulf of Mexico. The trace elemental ratios like V/Cr （〈2）, Ni/Co （〈2）, and Cu/Zn （〈1）, authigenic uranium content （〈1）, and Ce anomaly （Ce/Ce＊ ≤1） suggested that the sediments were deposited under an oxic condition, which was also revealed by the benthic foraminiferal assemblages throughout the GM6 and GM7 sediment cores.

关键词： Radiocarbon age Manganosite Weathering Palaeoredox condition Provenance Holocene Gulf of Mexico

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Tribological behavior of ammonium-based protic ionic liquid as lubricant additive

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Friction 2021年第1期9卷 169-178页

作者： Hong GUO patricia IGLESIAS Mechanical Engineering Department Rochester Institute of TechnologyNew York 14623-5603USA

In this study, the tribological behavior of an ammonium-based protic ionic liquid(PIL) as an additive in a base mineral oil(MO) is investigated on a steel–steel contact at room temperature and 100℃. Tri-[bis(2-hydroxyethylammonium)] citrate(DCi) was synthesized in a simple and low-cost way, and the ionic structure of DCi was confirmed by proton nuclear magnetic resonance(^(1)H NMR). The stability measurement of 1 wt% DCi to a MO was investigated, and the lubricating ability and anti-wear properties of DCi as an additive in MO were also examined using a custom-designed reciprocating ball-on-flat tribometer. Optical microscope and profilometry were used to obtain the worn morphology of the steel disks. Scanning electron microscopy(SEM) and energy dispersive X-ray spectroscopy(EDS) were carried out to investigate the wear mechanism and to analyze the surface interactions between the rubbing components. When 1 wt% DCi is added into the base MO, frictional performance is improved at both temperatures studied with a friction reduction of 29.0% and 35.5%, respectively. Moreover, the addition of 1 wt% DCi to MO reduced the wear volume 59.4% compared to the use of MO. An oxygen-richened tribolayer is confirmed by EDS on the disk surface when DCi was used as additive under 100℃.

关键词： protic ionic liquid(PIL) tri-[bis(2-hydroxyethylammonium)]citrate(DCi) steel–steel friction wear

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Three-dimensional models: from cell culture to Patient-Derived Organoid and its application to future liposarcoma research

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Oncology research 2025年第1期33卷 1-13页

作者： Sayumi Tahara Sydney Rentsch Fernanda Costas Casal DE Faria patricia Sarchet Roma Karna Federica Calore Raphael E Pollock Department of Surgery Division of Surgical Oncology The James Comprehensive Cancer Center The Ohio State University Wexner Medical Center Columbus OH 43210 USA. Department of Cancer Biology and Genetics The James Comprehensive Cancer Center The Ohio State University Wexner Medical Center Columbus OH 43210 USA.

Liposarcoma is one of the most common soft tissue sarcomas, however, its occurrence rate is still rare compared to other cancers. Due to its rarity, experiments are an essential approach to elucidate liposarcoma pathobiology. Conventional cell culture-based research (2D cell culture) is still playing a pivotal role, while several shortcomings have been recently under discussion. , mouse models are usually adopted for pre-clinical analyses with expectations to overcome the issues of 2D cell culture. However, they do not fully recapitulate human dedifferentiated liposarcoma (DDLPS) characteristics. Therefore, three-dimensional (3D) culture systems have been the recent research focus in the cell biology field with the expectation to overcome at the same time the disadvantages of 2D cell culture and animal models and fill in the gap between them. Given the liposarcoma rarity, we believe that 3D cell culture techniques, including 3D cell cultures/co-cultures, and Patient-Derived tumor Organoids (PDOs), represent a promising approach to facilitate liposarcoma investigation and elucidate its molecular mechanisms and effective therapy development. In this review, we first provide a general overview of 3D cell cultures compared to 2D cell cultures. We then focus on one of the recent 3D cell culture applications, Patient-Derived Organoids (PDOs), summarizing and discussing several PDO methodologies. Finally, we discuss the current and future applications of PDOs to sarcoma, particularly in the field of liposarcoma.

关键词： Cell culture Liposarcoma Patient-Derived Organoid (PDO) Spheroid Three-dimensional (3D) cell culture

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Adsorption desalination:Advances in porous adsorbents

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Chinese Journal of Chemical Engineering 2022年第2期35卷 151-169页

作者： Boya Qiu patricia Gorgojo Xiaolei Fan Department of Chemical Engineering and Analytical Science School of EngineeringThe University of ManchesterOxford RoadManchester M139PLUnited Kingdom Nanoscience and Materials Institute of Aragón(INMA)CSIC-Universidad de Zaragoza Mariano Esquillor50018 ZaragozaSpain Chemical and Environmental Engineering Department Universidad de ZaragozaPedro Cerbuna 1250009 ZaragozaSpain

With the continuous growth of the world population,the demand for fresh water is ever *** desalination is a means of producing fresh water from saline water,and one of the proposed solutions in the scientific community for solving the current global freshwater *** is foreseen as a promising technology for desalination due to its relatively low energy requirements,low environmental impact,low cost and high salt removal *** importantly,chemicals are not required in adsorption *** carbons,zeolites,carbon nanostructures,graphene and coordination framework materials are amongst the most investigated adsorbents for adsorption desalination,which show different performances regarding adsorption rate,adsorption capacity,stability and *** this review,the latest adsorbent materials with their features are assessed(using metrics)and commented critically,and the current trend for their development is *** adsorption mode is also reviewed,which can provide guidance for the design of adsorbents from the engineering application point of view.

关键词： Adsorption desalination Adsorbents Porous materials Operation modes

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Synchronous waving in fiddler crabs: a review

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Current Zoology 2019年第1期65卷 83-88页

作者： patricia Ruth Yvonne Backwell Research School of Biology The Australian National University Canberra ACT 2601 Australia

Many animals that use acoustic communication synchronize their mate attract!on signals: individuals precisely time their calls to overlap those of their neighbors. In contrast, synchrony in the mate attraction displays of species with visual/motion-based signals is rare. It has only been documented in five species of fiddler crabs. In all of them, small groups of males wave their single large claw in close synchrony. Here, I review what we know about synchrony in fiddler crabs, comparing the five species with each other to determine whether similar mechanisms and functions are comm on to all. I also propose future research questions that, if answered, would shed light on synchronous behavior in both visual and acoustic signallers.

关键词： fiddler crab synchrony waving mate choice wave timing visual signal

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Regulating autophagy:a novel role for SETX(Senataxin)

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Neural Regeneration Research 2021年第10期16卷 2008-2009页

作者： patricia Richard Emanuel Rosonina Stellate Therapeutics Inc. JLABS@NYCNew YorkUSA Department of Biology York UniversityTorontoCanada

Mutations in the gene encoding SETX,also known as Senataxin,are mainly linked to two distinct neurodegenerative diseases,a cerebellar ataxia known as oculomotor apraxia type 2(AOA2)and a form of juvenile amyotrophic l... 详细信息

关键词： al. diseases degenerative

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Orbit orientation in didelphid marsupials （Didelphimorphia： Didelphidae）

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Current Zoology 2017年第4期63卷 403-415页

作者： patricia PILATTI Diego ASTUA Laboratorio de Mastozoologia Departamento de Zoologia Universidade Federal de Pernambuco. Av. Prof. Moraes Rego S/N Cidade Universitaria Recife PE 50670-901 Brazil

Usually considered a morphologically conservative group, didelphid marsupials present consider- able variation in ecology and body size, some of which were shown to relate to morphological structures. Thus, changes on orbit morphology are likely and could be related to that variation. We calculated orbit orientation in 873 specimens of 16 Didelphidae genera yielding estimates of orbits convergence （their position relative to midsagittal line） and verticality （their position relative to frontal plane）. We then compared similarities in these variables across taxa to ecological, morpho- logical and phylogenetic data to evaluate the influencing factors on orbit orientation in didelphids. We found an inverse relation between convergence and verticality. Didelphids orbits have low ver- ticality but are highly convergent, yet orbit orientation differs significantly between taxa, and that variation is related to morphological aspects of the cranium. Rostral variables are the only morpho- logical features correlated with orbit orientation： increasing snout length yields more convergent orbits, whereas increase on snout breadth imply in more vertical orbits. Size and encephalization quotients are uncorrelated with orbit orientation. Among ecological data, diet showed significant correlation whereas locomotion is the factor that less affects the position of orbits. Phylogeny is uncorrelated to any orbital parameters measured. Ecological factors seemingly play a more import- ant role on orbit orientation than previously expected, and differentiation on orbit orientation seems to be more functional than inherited. Thus, despite the apparent homogeneity on didelphid morphology, there is subtle morphological variability that may be directly related to feeding behavior.

关键词： convergence Didelphidae frontation orbit orientation verticality.

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