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Surface Dyakonov-Cherenkov radiation

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eLight 2022年第1期2卷 24-31页

作者： Hao Hu Xiao Lin Liang jie wong Qianru yang Dongjue Liu Baile Zhang yu Luo School of Electrical and Electronic Engineering Nanyang Technological University50 Nanyang AvenueSingapore 639798Singapore Interdisciplinary Center for Quantum Information State Key Laboratory of Modern Optical InstrumentationZJU‑Hangzhou Global Science and Technology Innovation CenterCollege of Information Science and Electronic EngineeringZhejiang UniversityHangzhou 310027China International joint Innovation Center ZJU‑UIUC InstituteZhejiang UniversityHaining 314400China Division of Physics and Applied Physics School of Physical and Mathematical SciencesNanyang Technological University21 Nanyang LinkSingapore 637371Singapore Centre for Disruptive Photonic Technologies Nanyang Technological University21 Nanyang LinkSingapore 637371Singapore UMI 3288 CINTRA CNRS/NTU/THALESNanyang Technological University50 Nanyang DriveSingapore 637553Singapore.

Recent advances in engineered material technologies(e.g.,photonic crystals,metamaterials,plasmonics,etc.)provide valuable tools to control Cherenkov *** all these approaches,however,the particle velocity is a key parameter to affect Cherenkov radiation in the designed material,while the influence of the particle trajectory is generally ***,we report on surface Dyakonov-Cherenkov radiation,*** emission of directional Dyakonov surface waves from a swift charged particle moving atop a birefringent *** new type of Cherenkov radiation is highly susceptible to both the particle velocity and trajectory,*** observe a sharp radiation enhancement when the particle trajectory falls in the vicinity of a particular ***,close to the Cherenkov threshold,such a radiation enhancement can be orders of magnitude higher than that obtained in traditional Cherenkov *** distinct properties allow us to determine simultaneously the magnitude and direction of particle velocities on a compact *** surface Dyakonov-Cherenkov radiation studied in this work not only adds a new degree of freedom for particle identification,but also provides an all-dielectric route to construct compact Cherenkov detectors with enhanced sensitivity.

关键词： Cherenkov radiation Dyakonov surface wave Particle detector

翼状胬肉组织中胰岛素样生长因子结合蛋白-3的表达

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世界核心医学期刊文摘(眼科学分册) 2006年第12期 25-26页

作者： wong y.W. Chew j. R. Beuerman 王永强 Singapore Eye Research Institute c/o Singapore National Eye Centre 11 Third Hospital Avenue Singapore 168751 SingaporeProf.

Background: Pterygium is a fibrovascular overgrowth from the conjunctiva onto the cornea. The pathogenesis of this common ocular surface disorder is not well understood and the only treatment is surgical removal. Methods: DNA microarray analysis of primary pterygium tissue was carried out using uninvolved conjunctiva tissue as a comparison for gene expression levels. Real time polymerase chain reaction (PCR) was used to verify the mRNA level of expression for genes changed in pterygium. Western blot analysis and immunohistochemistry showed protein expression levels and the tissue distribution. Results: Microarray analysis revealed that mRNA levels of a number of genes were changed in primary pterygium. In particular the gene for insulin-like growth factor binding protein-3, (IGFBP3), which modulates the effects of insulin-like growth factor on cells was significantly decreased. Both the message and protein expression of IGFBP3 in pterygium were decreased compared to normal, uninvolved conjunctiva. Conclusion: Decreased levels of IGFBP3 protein have been strongly correlated with the presence of cancer. Identification of the low level of expression of IGFBP3 in pterygium suggests that the pathway controlling cell proliferation has lost an important control mechanism, which may explain the continued growth of pterygium.

关键词：翼状胬肉基因攀睛眼结膜炎胰岛素样生长因子结合蛋白

中国香港儿童和青少年的超重和肥胖情况及与体重相关的思想和行为

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世界核心医学期刊文摘（儿科学分册） 2005年第9期1卷 57-58页

作者： wong j.P.S. Ho S.y. LaiM.K. 李开 Department of Community Medicine University of Hong Kong 21 Sassoon Road Pokfulam Hong Kong

Aim: To study the prevalence of overweight and obesity, and weight-related concerns and behaviours among overweight, obese and non-overweight children and adolescents. Methods: We carried out a cross-sectional survey of all Chinese studentsin primary schools in the Central and Western District of Hong Kong in March 2002. Thirty-one of 32 schools participated, and 5402 boys and 5371 girls aged 8 to 15 y who completed a standardized questionnaire were included. We used the International Obesity Task Force definition (IOTF reference) to define overweight and obesity. Results: The prevalence (95% CI) of overweight was 16.4% (15.7-17.1% ) (19.9% in boys, 12.9% in girls), and that of obesity was 7.7% (7.2-8.2% )-(10.3% in boys and 5.1% in girls). The combined prevalence of overweight and obesity was similar to that based on the local reference. Overweight children had more concerns about their weight than obese children. They were more likely than obese children to feel fat, wish to be lighter, diet and exercise to lose weight. Although obese children were heavier, they did not make more effort to lose weight than overweight children. Conclusions: The differences in weight-related concernsand behaviours among overweight, obese and non-overweight children suggested good validity of the IOTF reference and the self-reported data. The differences between overweight and obese children suggested that the two groups had different psychological states and that they needed different weight management programmes and other intervention strategies.

关键词：体重控制肥胖儿童参考值正常体重问卷调查心理状态

CXCL10 plays a key role as an inflammatory mediator and a non-invasive biomarker of non-alcoholic steatohepatitis

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CXCL10 plays a key role as an inflammatory mediator and a no...

Antineutrino energy spectrum unfolding based on the Daya Bay measurement and its applications

第九届全国免疫学学术大会

作者： Xiang Zhang jiayun Shen Kwan Man Eagle S.H.Chu Tung On yau joanne C.y.Sung Minnie y.y.Go jun Deng Liwei Lu Vincent W.S.wong joseph j.y.Sung Geoffrey Farrell jun yu Institute of Digestive Disease and The Department of Medicine and Therapeutics State Key Laboratory of Digestive DiseaseThe Chinese University of Hong Kong

Perpetuate liver inflammation is crucial in the pathogenesis of non-alcoholic steatohepatitis(NASH).Expression of CXCL10,a pro-inflammatory cytokine that can recruit inflammatory cells to site of tissue damage,correlates positively with obesity and type 2 *** CXCL10 plays a role in NASH was *** we investigated the functional

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Chinese Physics C 2021年第7期45卷 1-19页

作者： F.P.An A.B.Balantekin M.Bishai S.Blyth G.F.Cao j.Cao j.F.Chang y.Chang H.S.Chen S.M.Chen y.Chen y.X.Chen j.Cheng Z.K.Cheng j.j.Cherwinka M.C.Chu j.P.Cummings O.Dalager F.S.Deng y.y.Ding M.V.Diwan T.Dohnal D.Dolzhikov j.Dove M.Dvorak D.A.Dwyer j.P.Gallo M.Gonchar G.H.Gong H.Gong M.Grassi W.Q.Gu j.y.Guo L.Guo X.H.Guo y.H.Guo Z.Guo R.W.Hackenburg S.Hans a M.He K.M.Heeger y.K.Heng y.K.Hor y.B.Hsiung B.Z.Hu j.R.Hu T.Hu Z.j.Hu H.X.Huang j.H.Huang X.T.Huang y.B.Huang P.Huber D.E.jaffe K.L.jen X.L.ji X.P.ji R.A.johnson D.jones L.Kang S.H.Kettel S.Kohn M.Kramer T.j.Langford j.Lee j.H.C.Lee R.T.Lei R.Leitner j.K.C.Leung F.Li H.L.Li j.j.Li Q.j.Li R.H.Li S.Li S.C.Li W.D.Li X.N.Li X.Q.Li y.F.Li Z.B.Li H.Liang C.j.Lin G.L.Lin S.Lin j.j.Ling j.M.Link26 L.Littenberg B.R.Littlejohn j.C.Liu j.L.Liu j.X.Liu C.Lu H.Q.Lu K.B.Luk B.Z.Ma X.B.Ma X.y.Ma y.Q.Ma R.C.Mandujano C.Marshall K.T.McDonald R.D.McKeown y.Meng j.Napolitano D.Naumov E.Naumova T.M.T.Nguyen j.P.Ochoa-Ricoux A.Olshevskiy H.-R.Pan j.Park S.Patton j.C.Peng C.S.j.Pun F.Z.Qi M.Qi X.Qian N.Raper j.Ren C.Morales Reveco R.Rosero B.Roskovec X.C.Ruan H.Steiner j.L.Sun T.Tmej1 K.Treskov W.-H.Tse C.E.Tull B.Viren V.Vorobel C.H.Wang j.Wang M.Wang N.y.Wang R.G.Wang W.Wang W.Wang X.Wang y.Wang y.F.Wang Z.Wang Z.Wang Z.M.Wang H.y.Wei L.H.Wei L.j.Wen K.Whisnant C.G.White H.L.H.wong E.Worcester D.R.Wu F.L.Wu Q.Wu W.j.Wu D.M.Xia Z.Q.Xie Z.Z.Xing H.K.Xu j.L.Xu T.Xu T.Xue C.G.yang L.yang y.Z.yang H.F.yao M.ye M.yeh B.L.young H.Z.yu Z.y.yu B.B.yue V.Zavadskyi S.Zeng y.Zeng L.Zhan C.Zhang F.y.Zhang H.H.Zhang j.W.Zhang Q.M.Zhang S.Q.Zhang X.T.Zhang y.M.Zhang y.X.Zhang y.y.Zhang Z.j.Zhang Z.P.Zhang Z.y.Zhang j.Zhao R.Z.Zhao L.Zhou H.L.Zhuang j.H.Zou Institute of Modern Physics East China University of Science and TechnologyShanghai 200337 University of Wisconsin MadisonWisconsin 53706 Brookhaven National Laboratory UptonNew York 11973 Department of Physics Nnational Taiwan UniversityTaipei Institute of High Energy Physics Beijing 100049 National United University Miao-Li Department of Engineering Physics Tsinghua UniversityBeijing 100048 Shenzhen University Shenzhen 518061 Sun yat-Sen(Zhongshan)University Guangzhou 510275 North China Electric Power University Beijing 102206 Chinese University of Hong Kong Hongkong 999077 Siena College LoudonvilleNew York 12211 Department of Physics and Astronomy University of CaliforniaIrvineCalifornia 92697 University of Science and Technology of China Hefei 230022 Charles University Faculty of Mathematics and PhysicsPrague joint Institute for Nuclear Research DubnaMoscow Region Department of Physics University of Illinois at Urbana-ChampaignUrbanaIllinois 61801 Lawrence Berkeley National Laboratory BerkeleyCalifornia 94720 Department of Physics Illinois Institute of TechnologyChicagoIllinois 60616 Beijing Normal University Beijing 100875 Department of Nuclear Science and Technology School of Energy and Power EngineeringXi'an Jiaotong UniversityXi'an 710049 Wright Laboratory and Department of Physics Yale UniversityNew HavenConnecticut 06520 China Institute of Atomic Energy Beijing 102413 Shandong University Jinan 250002 Guangxi University No.100 Daxue East RoadNanning 530004 Center for Neutrino Physics Virginia TechBlacksburgVirginia 24061 Institute of Physics NCTUHsinchu Department of Physics University of CincinnatiCincinnatiOhio 45221 Department of Physics College of Science and TechnologyTemple UniversityPhiladelphiaPennsylvania 19122 Dongguan University of Technology Dongguan 523808 Department of Physics University of CaliforniaBerkeleyCalifornia 94720 Department of Physics The University of Hong KongPokfulamHongkong 999077 School of Physics Nankai UniversityTianjin 300071 Department o

The prediction of reactor antineutrino spectra will play a crucial role as reactor experiments enter the precision *** positron energy spectrum of 3.5 million antineutrino inverse beta decay reactions observed by the Daya Bay experiment,in combination with the fission rates of fissile isotopes in the reactor,is used to extract the positron energy spectra resulting from the fission of specific *** information can be used to produce a precise,data-based prediction of the antineutrino energy spectrum in other reactor antineutrino experiments with different fission fractions than Daya *** positron energy spectra are unfolded to obtain the antineutrino energy spectra by removing the contribution from detector response with the Wiener-SVD unfolding *** results are obtained with other unfolding methods.A technique to construct a data-based prediction of the reactor antineutrino energy spectrum is proposed and *** the reactor fission fractions,the technique can predict the energy spectrum to a 2%*** addition,we illustrate how to perform a rigorous comparison between the unfolded antineutrino spectrum and a theoretical model prediction that avoids the input model bias of the unfolding method.

关键词： reactor antineutrino energy spectrum Daya Bay application

慢性乙型肝炎病毒携带者肝纤维化及脾硬度定量弹力成像:剪切波及瞬时弹力成像与肝活检的相关性

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国际医学放射学杂志 2014年第1期 81-82页

作者： V.y.Leung j.Shen V.W.wong j.Abrigo G.L.wong A.M.Chim 谷磊磊 Institute of Digestive Disease Prince of Wales HospitalThe Chinese University of Hong KongNgan Shing StreetShatinHong KongSARChina 852

目的探讨剪切波(SW)弹性成像评价慢性乙型肝炎病毒携带者肝纤维化的可行性,及与瞬时弹力成像所见比较。方法本研究得到伦理委员会同意,并签署知情同意书。

关键词：慢性乙型肝炎病毒肝纤维化肝疾病携带者弹性成像弹力肝活检剪切波相关性

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专业的眼科保健机构对未诊断青光眼的检测

世界核心医学期刊文摘（眼科学分册） 2005年第2期1卷 60-61页

作者： wong E.y.H. Keeffe j.E. Rait j.L. 王建洲 CERA Locked Bag 8 Eas t Melbourne Vic. 3002 Australia

Purpose To examine the clinical features of undiagnosed openangle glaucoma (OA G) in people who have attended an eye care provider within the previous 12 month s and to suggest strategies to assist in the early detection of glaucoma. Design Population based cross-sectional study. Participants Permanent residents aged 40 years and older at recruitment during 1992 through 1996. Methods A cluster-s tratified random sample of 4744 participants from the urban and rural cohorts wa s studied. Structured standardized interviews and dilated ocular examinations we re conducted in all eligible participants. Data on demographic characteristics, prior knowledge of eye disease, use of eye care services, intraocular pressures, cup-to-disc ratios, visual fields, and photographyof optic discs were obtaine d. All suspected glaucoma cases were submitted to a panel of 6 ophthalmologists to determine glaucoma diagnosis. Main outcome measures Clinical features of part icipants seen by eye health professionals within the previous 12 months who have previously undiagnosed OAG, previously diagnosed OAG, and no glaucoma. Results Thirty-five previously undiagnosed and 43 previously diagnosed participants had visited an optometrist or ophthalmologist or both in the previous 12 months. Ag e and gender were not significantly different between the undiagnosed and diagno sed glaucoma cases. After logistic regression, the type of eye professional seen (odds ratio OR, 45.17; 95%confidence interval 95%CI, 5.89-346.17; P=0.00 02) and the presence of visual field defects (OR, 0.06; 95%CI, 0.01-0.69, P=0. 020)were the only statistically sig nificant variables between the diagnosed and undiagnosed glaucoma groups. Conc lusions Raised intraocular pressure should not be relied on as the only triggeri ng factor in glaucoma investigations.

关键词：保健机构眼保健视野缺损眼内压杯盘比健康普查居住人群验光师启动因素统计学显著性

肝内乙肝病毒共价闭合环DNA可作为治疗持续应答的预测指标

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世界核心医学期刊文摘（胃肠病学分册） 2005年第10期1卷 28-29页

作者： Sung j.j.y. wong M.-L. Bowden S. 李宏宇 Department of Medicine and Therapeutics Prince of Wales Hospital Chinese University of Hong Kong Hong Kong SAR Hong Kong Dr.

Background &Aims: This study aimed to determine whether intrahepatic hepatitis B virus (HBV) covalently closed circular (ccc) DNA and total HBV DNA levels at the end of therapy would predict sustained response to therapy. Methods: Hepatitis B e antigen (HBeAg)positive chronic hepatitis B patients receiving either lamivudine monotherapy or combination of peginterferon and lamivudine had liver biopsy at the end of 1 year therapy and were followed for 52 more weeks after cessation of therapy. Serum HBV DNA, intrahepatic HBV ccc DNA, and total HBV DNA levels were determined. Results: Forty-seven patients, including 34 males and 13 females, were studied. Twenty-seven patients received combination therapy, and 20 patients received lamivudine monotherapy. Twentynine patients had end-of-treatment virologic response, and 15 patients had sustained response 52 weeks after therapy. At the end of treatment, log serum HBV DNA levels correlated well with log intrahepatic HBV cccDNA and log intrahepatic total HBV DNA levels. Log intrahepatic cccDNA and log intrahepatic total DNA levels were significantly lower among patients with sustained virologic response. The adjusted odds ratio for log cccDNA was 5.3 (95%CI: 1.5-18.2, P =. 009) and, for log intrahepatic HBV DNA, was 4.4 (95%CI: 1.3-14.7, P =. 015) to predict sustained virologic response. Using log cccDNA at -0.80 copies/genome equivalent as cutoff, the sensitivity, specificity, and positive and negative predictive values and accuracy of predicting sustained virologic response were 73%, 78%, 56%, 86%, and 77%respectively. Conclusions: Intrahepatic HBV cccDNA and intrahepatic total HBV DNA levels at the end of therapy are superior to serum HBV DNA as surrogates of sustained virologic response.

关键词： DNA 持续应答乙肝病毒闭合环病毒应答乙型肝炎病毒病毒学应答聚乙二醇干扰素肝组织活检随访疗效

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视网膜病与充血性心力衰竭的危险

美国医学会杂志（中文版） 2006年第1期25卷 22-27页

作者： Tien y. wong Wayne Rosamond patricia P. Chang David j. Couper A. Rickey Sharrett Larry D. Hubbard Aaron R. Folsom Ronald Klein 范琰（译）刘梅林（校） Centre for Eye Research Australia University of Melbourne Victoria Singapore Eye Research Institute National University of Singapore Department of Epiderniology Division of Cardiology Department of Biostatistics University of North Carolina Chapel Hill Department of Epidemiology Johns Hopkins University Baltimore Md Department of Ophthalmology Uni- versity of Wisconsin Madison Division of Epidemiology University of Minnesota Minneapolis 不详

摘要：充血性心力衰竭（congestive heart failure，CHF）影响了相当一部分成年人，包括既往没有冠心病的人群。CHF的病因还不完全清楚，但是微血管病是可能的因素之一。目的：明确视网膜病作为全身微血管疾病的一个标志与CHF的关系。... 详细信息

摘要：充血性心力衰竭（congestive heart failure，CHF）影响了相当一部分成年人，包括既往没有冠心病的人群。CHF的病因还不完全清楚，但是微血管病是可能的因素之一。目的：明确视网膜病作为全身微血管疾病的一个标志与CHF的关系。设计、地点、参试者：应用动脉粥样硬化危险社区研究资料库，在美国4个社区进行的长达7年的人群前瞻性队列研究。参试者（n=1l612，年龄49—73岁）于1993—1995年曾行视网膜照相。视网膜照相根据标准按照视网膜病（如微血管瘤、视网膜出血、软渗出）、动静脉压迹、局限性小动脉狭窄和普遍小动脉狭窄分级。主要结局指标：视网膜病与CHF的关系，后者经由住院及死亡记录证实。结果：7年累计CHF发生率为5．4％（492例）。与没有视网膜病的参试者比较，有视网膜病的参试者CHF的发生率较高（15．1比4．8，P〈0．001）。在校正年龄、性别、种族、已有冠心病、平均动脉压、糖尿病、血糖水平、胆固醇水平、吸烟、体重指数（BMI）和研究地点后，视网膜病的存在与CHF发病危险增加2倍相关（相对危险，1．96；95％可信区间，1．51—2．54）。在既往没有冠心病、糖尿病或高血压的参试者中，有视网膜病者发生CHF的危险增加3倍（相对危险，2．98；95％可信区间，1．50—2．92）。结论：视网膜病是CHF的独立危险预测因素，即使是在没有冠心病、糖尿病或高血压的人群。这提示，微血管疾病可能对普通人群心力衰竭的发病具有重要的作用。某些眼科检查发现无症状视网膜病的患者，可从进一步的CHF危险评估受益。

关键词：充血性心力衰竭视网膜病 failure 前瞻性队列研究微血管疾病普通人群动脉粥样硬化 CHF 社区研究动脉狭窄