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Hydrogen-based direct reduction of industrial iron ore pellets:Statistically designed experiments and computational simulation

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International Journal of Minerals,Metallurgy and Materials 2022年第10期29卷 1908-1921页

作者： patrícia Metolina Tiago Ramos Ribeiro Roberto Guardani Chemical Systems Engineering Center Department of Chemical EngineeringUniversity of São PauloSão Paulo 05508-900Brazil Metallurgical Process Laboratory Institute of Technological ResearchSão Paulo 05508-901Brazil

As part of efforts to reduce anthropogenic CO_(2) emissions by the steelmaking industry,this study investigated the direct reduction of industrially produced hematite pellets with H_(2) using the Doehlert experimental design to evaluate the effect of pellet diameter(10.5-16.5 mm),porosity(0.36-0.44),and temperature(600-1200℃).A strong interactive effect between temperature and pellet size was observed,indicating that these variables cannot be considered *** increase in temperature and decrease in pellet size considerably favor the reduction rate,while porosity did not show a relevant *** change in pellet size during the reduction was negligible,except at elevated temperatures due to crack formation.A considerable decrease in mechanical strength at high temperatures suggests a maximum process operating temperature of 900℃.Good predictive capacity was achieved using the modified grain model to simulate the three consecutive non-catalytic gas-solid reactions,considering different pellet sizes and porosities,changes during the reaction from 800 to 900℃.However,for other temperatures,different mechanisms of structural modifications must be considered in the *** results represent significant contributions to the development of ore pellets for CO_(2)-free steelmaking technology.

关键词： hydrogen use non-catalytic gas-solid reaction grain model porous hematite pellet CO_(2)emissions reduction Doehlert experimental design

Spherical f-Tilings by Two Noncongruent Classes of Isosceles Triangles-Ⅱ

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Acta Mathematica Sinica,English Series 2014年第8期30卷 1435-1464页

作者： Ana BREDA Robert DAWSON patrícia RIBEIRO Department of Mathematics University of Aveiro Department of Mathematics and Computing Science Saint Mary’s University Halifax Department of Mathematics EST SetbalPolytechnic Institute of Setbal

In this work,we give a complete classification of spherical dihedral f-tilings when the prototiles are two noncongruent isosceles triangles with certain adjacency *** it will be shown,this class is composed by two dis... 详细信息

关键词： Spherical tilings dihedral triangulations f-tilings spherical trigonometry

Population viability analysis: using a modeling tool to assess the viability of tapir populations in fragmented landscapes

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Integrative Zoology 2012年第4期7卷 356-372页

作者： Emília patrícia MEDICI Arnaud Leonard Jean DESBIEZ Lowland Tapir Conservation Initiative IPÊ-Institute for Ecological ResearchNazaréPaulistaSão PauloBrazil IUCN/SSC Tapir Specialist Group(TSG) GlandSwitzerland Escola Superior de Conservação Ambiental e Sustentabilidade(ESCAS/IPÊ) NazaréPaulistaSão PauloBrazil IUCN/SSC Conservation Breeding Specialist Group(CBSG) Brazil NetworkCampo GrandeMSBrazil Royal Zoological Society of Scotland EdinburghScotland

A population viability analysis(PVA)was conducted of the lowland tapir populations in the Atlantic Forest of the Pontal do Paranapanema region,Brazil,including Morro do Diabo State Park(MDSP)and surrounding forest *** from the model projected that the population of 126 tapirs in MDSP is likely to per-sist over the next 100 years;however,200 tapirs would be required to maintain a viable ***-ity analysis showed that sub-adult mortality and adult mortality have the strongest influence on the dynamics of lowland tapir *** road-kill has a major impact on the MDSP tapir population and can lead to population *** modeling showed that dispersal of tapirs from MDSP to the surrounding fragments can be detrimental to the overall metapopulation,as fragments act as ***,the model showed that under certain conditions the maintenance of the metapopulation dynamics might be determinant for the persistence of tapirs in the region,particularly in the smaller *** establishment of corridors con-necting MDSP to the forest fragments models resulted in an increase in the stochastic growth rate,making ta-pirs more resilient to threats and catastrophes,but only if rates of mortality were not increased when using *** PVA showed that the conservation of tapirs in the Pontal region depends on:the effective protection of MDSP;maintenance and,whenever possible,enhancement of the functional connectivity of the landscape,reducing mortality during dispersal and threats in the unprotected forest fragments;and neutralization of all threats affecting tapirs in the smaller forest fragments.

关键词： Atlantic Forest fragmentation lowland tapir minimum viable population population viability analysis

Incidence of hepatocellular carcinoma in patients with chronic liver disease due to hepatitis B or C and coinfected with the human immunodeficiency virus:a retrospective cohort study

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World Journal of Gastroenterology 2018年第5期24卷 613-622页

作者： patrícia dos Santos Marcon Cristiane Valle Tovo Dimas Alexandre Kliemann patrícia Fisch Angelo Alves de Mattos Hepatology Post-Graduate Program Universidade Federal de Ciências da Saúde de Porto Alegre(UFCSPA)Porto Alegre 90020-090RSBrazil Infectology Department at Hospital Nossa Senhora da Conceicao Porto Alegre 91350-200RSBrazil Epidemiology Department at Hospital Nossa Senhora da Conceicao Porto Alegre 91350-200RSBrazil

AIM To assess the incidence of hepatocellular carcinoma(HCC) in chronic liver disease due to hepatitis B virus(HBV) or hepatitis C virus(HCV) coinfected with human immunodeficiency virus(HIV).METHODS A retrospective cohort study was performed, including patients with chronic liver disease due to HBV or HCV, with and without HIV coinfection. Patients were selected in the largest tertiary public hospital complex in southern Brazil between January 2007 and June 2014. We assessed demographic and clinical data, including lifestyle habits such as illicit drug use or alcohol abuse, in addition to frequency and reasons for hospital admissions via medical records *** Of 804 patients were included(399 with HIV coinfection and 405 monoinfected with HBV or HCV). Coinfected patients were younger(36.7 ± 10 vs 46.3 ± 12.5, P < 0.001). Liver cirrhosis was observed in 31.3% of HIV-negative patients and in 16.5% of coinfected(P < 0.001). HCC was diagnosed in 36 patients(10 HIV coinfected and 26 monoinfected). The incidence density of HCC in coinfected and monoinfected patients was 0.25 and 0.72 cases per 100 patient-years(95%CI: 0.12-0.46 vs 0.47-1.05)(long-rank P = 0.002), respectively. The ratio for the HCC incidence rate was 2.98 for HIV-negative. However, when adjusting for age or when only cirrhotic are analyzed, the absence of HIV lost statistical significance for the development of HCC. CONCLUSION In this study, the presence of HIV coinfection in chronic liver disease due to HBV or HCV showed no relation to the increase of HCC incidence.

关键词： Hepatocellular carcinoma Chronic hepatitis human immunodeficiency virus Coinfection Cirrhosis

Aeration and sawdust application effects as structural material in the bioremediation of clayey acid soils contaminated with diesel oil

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International Soil and Water Conservation Research 2018年第3期6卷 253-260页

作者： Gabriela Menta Alvim patrícia Procópio Pontes Department of Environmental Science and Technology Federal Centre for Technological Education of Minas Gerais525330-421169 Belo HorizonteBrazil

Soil contamination, due to the leakage of petroleum or its by-products, is a reason for concern nowadays. Technologies, such as bioremediation, have been developed to remove these pollutants from the environment. This paper aims to evaluate the bioremediation of clayey acid soils contaminated with diesel oil, comparing the effect of aeration use and the addition of different sawdust ratios (5% and 10%) as bulking material. This research was developed in three phases, with experiments of (a) natural attenuation (exclusively natural processes), (b) sawdust-amended soil and (c) aeration combined with sawdust addition. The manometric respirometry test was applied to monitor CO2 production during biodegradation experiments and sodium hydroxide (NaOH) was used as an absorbent solution. The contamination of the samples was carried out by the addition of diesel oil (5% w/w (gg-1)) into the soil. The results indicated that natural attenuation presented a slower bioremediation process when compared to the treatments with sawdust addition. The addition of 5% of sawdust was beneficial to the microbial activity of the soil, but a proportion above 5% caused a negative effect on the samples, reducing the microbial activity. Statistical analysis (Kruskal-Wallis test) showed significant oil removals on experiments with the combination of sawdust and aeration. The aeration was considered the main agent in increasing oil biodegradation in the soil. The degradation rate reactions followed a zero-order linear model. The highest contaminant degradation rate was observed in the samples with 5% of sawdust and aeration (24.79 mgO2 kg-1dry soil day-1), which also improved microbial activity and diesel oil removal.

关键词： Bioremediation Diesel oil Contaminated soil Sawdust Aeration

How are children with medical complexity being identified in epidemiological studies?A systematic review

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World Journal of Pediatrics 2023年第10期19卷 928-938页

作者： patrícia Vicente Oliveira Carla C.Enes Luciana B.Nucci Postgraduate Program in Health Sciences Center for Life SciencesPontifical Catholic University of CampinasAv.John Boyd Dunlop s/nCampinasCEP 13060-904Brazil Postgraduate Program in Health Sciences School of NutritionPontifical Catholic University of CampinasSão PauloBrazil Postgraduate Program in Health Sciences School of MedicinePontifical Catholic University of CampinasSão PauloBrazil

Background There are different definitions to identify/classify children with medical complexity(CMC).We aimed to investigate and describe the definitions used to classify CMC in epidemiological *** PubMed,SciELO,LILACS,and EMBASE were searched from 2015 to 2020(last updated September 15th,2020)for original studies that presented the definition used to classify/identify CMC in the scientific research *** applied the Preferred Reporting Items for Systematic Reviews and Meta-Analyses *** the included studies,the following were identified:first author,year of publication,design,population,study period,the definition of CMC used,limitations,and *** Nine hundred and sixty-seven records were identified in the searched databases,and 42 met the inclusion *** the 42 studies included,the four most frequent definitions used in the articles included in this review were classification of CMC into nine diagnostic categories based on the International Classification of Diseases,Ninth Revision(ICD-9)(35.7%,15 articles);update of the previous classification for ICD-10 codes with the inclusion of other conditions in the definition(21.4%,nine articles);definition based on a medical complexity algorithm for classification(16.7%,seven articles);and a risk rating system(7.1%,three articles).Conclusions CMC definitions using diagnostic codes were more ***,several limitations were found in its *** research highlighted the need to improve health information systems to accurately characterize the CMC population and promote the provision of comprehensive care.

关键词： Children with medical complexity Complex chronic conditions Epidemiologic studies Pediatrics Systematic review

Tapir health and conservation medicine

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Integrative Zoology 2012年第4期7卷 331-345页

作者： Paulo Rogerio MANGINI Emilia patrícia MEDICI Renata Carolina FERNANDES-SANTOS Lowland Tapir Conservation Initiative IPÊ-Institute for Ecological ResearchNazaréPaulistaSão PauloBrazil Brazilian Institute for Conservation Medicine-TRÍADE RecifePernambucoBrazil IUCN/SSC Tapir Specialist Group(TSG) GlandSwitzerland IUCN/SSC Wildlife Health Specialist Group(WHSG) New YorkNYUSA IUCN/SSC Peccary Specialist Group(PSG) GlandSwitzerland Escola Superior de Conservação Ambiental e Sustentabilidade(ESCAS/IPÊ) NazaréPaulistaSão PauloBrazil IUCN/SSC Conservation Breeding Specialist Group(CBSG) Brazil NetworkCampo GrandeBrazil

Tapirs have unique nutritional needs,as well as anatomical,physiological,behavioral and ecological adapta-tions that must be considered when managing their health,both in the wild and in *** about how tapirs live in their natural habitats can provide crucial knowledge to prevent many of the health problems found in captivity such as infectious and parasitic diseases,reproductive issues and nutritional and behavior-al ***,proper management in captivity can significantly contribute to in situ conservation *** medicine is a science created to address the global health crisis that jeopardizes biodiver-sity causing imbalances among ecosystem,human,animal and vegetal *** this context,common threats to tapir health and conservation,such as isolated and small populations surrounded by human activity,chemical pollution,domestic animals and their pathogenic agents,need to be better *** manuscript provides information about the health of tapirs both in captivity and in the wild and aims to encourage tapir conservation-ists worldwide to gather information about pathogen and disease dynamics and manifestation,as well as impli-cations for tapir conservation.

关键词： captive management conservation medicine tapirs wildlife health

Cell-based therapeutic strategies for treatment of spinocerebellar ataxias:an update

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Neural Regeneration Research 2023年第6期18卷 1203-1212页

作者： Joana Sofia Correia Sara Duarte-Silva António JoséSalgado patrícia Maciel Life and Health Sciences Research Institute(ICVS) School of MedicineUniversity of MinhoBragaPortugal ICVS/3B’s–PT Government Associate Laboratory BragaGuimarãesPortugal

Spinocerebellar ataxias are heritable neurodegenerative diseases caused by a cytosine-adenine-guanine expansion,which encodes a long glutamine tract(polyglutamine)in the respective wild-type protein causing misfolding and protein *** features of polyglutamine spinocerebellar ataxias include neuronal aggregation,mitochondrial dysfunction,decreased proteasomal activity,and autophagy *** polyglutamine protein aggregates accumulate within neurons and cause neural dysfunction and death in specific regions of the central nervous *** ataxias are mostly characterized by progressive ataxia,speech and swallowing problems,loss of coordination and gait *** the past decade,efforts have been made to ameliorate disease symptoms in patients,yet no cure is *** studies have been proposing the use of stem cells as promising tools for central nervous system tissue *** far,pre-clinical trials have shown improvement in various models of neurodegenerative diseases following stem cell transplantation,including animal models of spinocerebellar ataxia types 1,2,and ***,contrasting results can be found in the literature,depending on the animal model,cell type,and route of administration ***,clinical trials using cellular implants into degenerated brain regions have already been applied,with the expectation that these cells would be able to differentiate into the specific neuronal subtypes and re-populate these regions,reconstructing the affected neural ***,the question of how feasible it is to continue such treatments remains unanswered,with long-lasting effects being still *** establish the value of these advanced therapeutic tools,it is important to predict the actions of the transplanted cells as well as to understand which cell type can induce the best outcomes for each *** studies are needed to determine the best route of administration,without neglec

关键词： cell transplantation engraftment induced pluripotent stem cells mesenchymal stem cells neural progenitor cells neuroprotection polyglutamine spinocerebellar ataxias secretome spinocerebellar ataxia stem cell therapy

Addressing soil protection concerns in forest ecosystem management under climate change

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Forest Ecosystems 2020年第3期7卷 432-442页

作者： Ana Raquel Rodrigues Brigite Botequim Catarina Tavares patrícia Pécurto JoséGBorges Forest Research Centre School of AgricultureLisbon UniversityTapada da Ajuda1349-017LisbonPortugal

Background: Climate change may strongly influence soil erosion risk, namely through variations in the precipitation pattern. Forests may contribute to mitigate the impacts of climate change on soil erosion and forest managers are thus challenged by the need to define strategies that may protect the soil while addressing the demand for other ecosystem services. Our emphasis is on the development of an approach to assess the impact of silvicultural practices and forest management models on soil erosion risks under climate change. Specifically, we consider the annual variation of the cover-management factor(C) in the Revised Universal Soil Loss Equation over a range of alternative forest management models to estimate the corresponding annual soil losses, under both current and changing climate conditions. We report and discuss results of an application of this approach to a forest area in Northwestern Portugal where erosion control is the most relevant water-related ecosystem ***: Local climate change scenarios will contribute to water erosion processes, mostly by rainfall erosivity *** forest management models provide varying levels of soil protection by trees, resulting in distinct soil loss ***: Results confirm the suitability of the proposed approach to address soil erosion concerns in forest management planning. This approach may help foresters assess management models and the corresponding silvicultural practices according to the water-related services they provide.

关键词： C-factor Erosivity Ecosystem services Forest management Revised universal soil loss equation(RUSLE)