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Coar.e to Fine: The r.le of Sever. Plastic Defor.ation in Advancing Titanium-Based Medical Implants - A Compr.hensive r.view

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Jour.al of Wuhan Univer.ity of Technology(Mater.als Science) 2025年第1期40卷 295-306页

作者： Dr.gana r.Mihajlović Bojan I Međo Ivana Lj Cvijović-Alagić Veljko r.Djokić Faculty of Technology and Metallur.y University of BelgradeKarnegijeva 411120 BelgradeSerbia Vinča Institute of Nuclear.Sci-ences-National Institute of the r.public of Ser.ia University of Belgrade11001BeogradSerbia Innovation Centr. of the Faculty of Technology and Metallur.y Karnegijeva 411120 BelgradeSerbia

This paper.descr.bes sever. plastic defor.ation(SPD)pr.cedur.s,which ar. utilized to for. an ultr.fine-gr.ined str.ctur. in metallic *** the SPD pr.cess,a solid mater.al sample is subjected to ver. high loads without a significant change in sample *** the pr.sent wor.,the high-pr.ssur. tor.ion(HPT)pr.cess,as one of the SPD techniques,which achieves a high degr.e of defor.ation and ensur.s r.finement of the micr.str.ctur.,will be discussed in mor. *** that gr.in size contr.l is accepted as a method to obtain mater.als with desir.d char.cter.stics,an over.iew of the pr.per.ies of ultr.fine-gr.ined titanium-based biomater.als to be used in medicine is ***,par.icular.attention is dedicated to the influences of HPT pr.cess par.meter.,pr.mar.ly hydr.static pr.ssur.,and number.of r.volutions dur.ng tor.ion,on the gr.in size and physical and mechanical char.cter.stics(modulus of elasticity,micr.har.ness,and tensile pr.per.ies),cor.osion r.sistance,and biocompatibility of the titanium-based biomater.als.A r.view of the liter.tur. indicates that titanium-based mater.als obtained by the SPD pr.cess show impr.ved mechanical and physical pr.per.ies without losing biocompatibility and cor.osion r.sistance,which suggests that these methods of obtaining implants ar. something that should be fur.her.developed in the futur..

关键词： high-pr.ssur. tor.ion pr.cess ultr.fine-gr.ined titanium-based mater.als electr.chemical anodization physical pr.per.ies mechanical pr.per.ies

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Emer.ing potential of pr.gr.nulin-dependent Sor.S2 signaling in healthy and diseased ner.ous systems

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Neur.l r.gener.tion r.sear.h 2025年第9期20卷 2591-2593页

作者： Alena Salasova Ander. Nykjær Danish r.sear.h Institute of Tr.nslational Neur.science DANDr.TE-Nor.ic EMBL Par.ner.hip for.Molecular.Medicine and Centre of Excellence PROMEMODepartment of BiomedicineAarhus UniversityAarhusDenmark

The for.ation of the mammalian ner.ous system and its matur.tion into sensor.,motor.cognitive,and behavior.l cir.uits is a complex pr.cess that begins dur.ng ear.y embr.ogenesis and lasts until young *** neur.developm... 详细信息

关键词： pr.gr jointly CS2

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Secur.ty Str.tegy of Digital Medical Contents Based on Blockchain in Gener.tive AI Model

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Computer., Mater.als & Continua 2025年第1期82卷 259-278页

作者： Hoon Ko Mar.k r.Ogiela Division of Computer.Science and Engineer.ng Sunmoon UniversityAsan31460Republic of Korea AGH Univer.ity of Kr.kow Cryptography and Cognitive Informatics LaboratoryKrakow30-059Poland

This study pr.sents an innovative appr.ach to enhancing the secur.ty of visual medical data in the gener.tive AI envir.nment thr.ugh the integr.tion of blockchain *** combining the str.ngths of blockchain and gener.tive AI,the r.sear.h team aimed to addr.ss the timely challenge of safeguar.ing visual medical *** par.icipating r.sear.her. conducted a compr.hensive analysis,examining the vulner.bilities of medical AI ser.ices,per.onal infor.ation pr.tection issues,and over.ll secur.ty *** multi faceted explor.tion led to an indepth evaluation of the model’s per.or.ance and ***,the cor.elation between accur.cy,detection r.te,and er.or.r.te was *** analysis r.vealed insights into the model’s str.ngths and limitations,while the consider.tion of standar. deviation shed light on the model’s stability and per.or.ance *** study pr.posed pr.ctical impr.vements,emphasizing the r.duction of false negatives to enhance detection r.te and lever.ging blockchain technology to ensur. visual data integr.ty in medical *** blockchain to gener.tive AI-cr.ated medical content addr.sses key per.onal infor.ation pr.tection *** utilizing the distr.buted ledger.system of blockchain,the r.sear.h team aimed to pr.tect the pr.vacy and integr.ty of medical data especially medical *** appr.ach not only enhances secur.ty but also enables tr.nspar.nt and tamper.r.of ***,the use of gener.tive AI models ensur.s the cr.ation of novel medical content without compr.mising per.onal infor.ation,fur.her.safeguar.ing patient *** conclusion,this study showcases the potential of blockchain-based solutions in the medical field,par.icular.y in secur.ng sensitive medical data and pr.tecting patient *** pr.posed appr.ach,combining blockchain and gener.tive AI,offer. a pr.mising dir.ction towar. mor. r.bust and secur. medical content *** r.sear.h and advancements

关键词： Digitalmedical content medical diagnostic visualization secur.ty analysis gener.tiveAI blockchain vulner.bility patter. r.cognition

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Antisense oligonucleotides pr.vide optimism to the ther.peutic landscape for.tauopathies

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Neur.l r.gener.tion r.sear.h 2025年第3期20卷 803-804页

作者： Glenn A.Har.is Laur.n r.Hir.chfeld r.inwater.Char.table Foundation Fort WorthTXUSA

Tauopathies ar. a gr.up of neur.degener.tive diseases char.cter.zed by abnor.al metabolism of the misfolded tau pr.tein. Tau is encoded by the micr.tubule-associated pr.tein tau gene(MAPT) and can be classified as either.3-r.peat(3r. or.4-r.peat(4r. based on the number.of r.peat domains fr.m alter.ative splicing of exon 10 of the MAPT gene.

关键词： tau metabolism diseases

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Coal washing scenar.o in India and futur. pr.spects

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Inter.ational Jour.al of Coal Science & Technology 2016年第2期3卷 191-197页

作者： r. Venugopal J. P. patel.C. Bhar Dept. of Fuel and Miner.l Engineer.ng Indian School ofMines Dhanbad Jharkhand 826004 India Washer. Division Bharat Coking Coal Limited SaraidhelaDhanbad Jharkhand 828127 India Dept. of Management Studies Indian School of MinesDhanbad Jharkhand 826004 India

Coal Washing Explor.tion in India dates back to 1900s; though, fir.t coking coal washer.es in India wer. installed after.independence. At pr.sent, most of the coking coal washer.es ar. owned by Public Sector.Companies; wher.as, most of the non-coking coal washer.es ar. owned by Pr.vate Sector. Even after.six decades of coal washing pr.ctices, ther. has not been significant development in the coal washing intelligentsia. Indian Coal Washing industr. is still dependent on impor.ed equipment, which has been designed to tr.at coal that is significantly differ.nt fr.m Indian coal of dr.ft or.gin. In this paper. author. have ventur.d into evolution of Indian Coal Washing Industr. （with a focus on coking coal washing sector., its pr.sent condition and futur. pr.spect for.gr.wth. The paper.emphasizes need for.developing indigenous solutions to industr.al challenges and highlights impor.ance of incr.ased coor.ination among academia-r.sear.h institutions and coal industr..

关键词： Coking coal washing Indian coal industr. Histor. of coal washing Futur. pr.spects

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Magnetohydr.dynamics bio-convection flow at Casson fluid stagnation point in por.us medium:Cr.ss-diffusion effect and heat pr.duction

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Pr.pulsion and Power.r.sear.h 2024年第3期13卷 445-457页

作者： Snehal patel.Har.had r.patel Gujar.t Technological Univer.ity AhmedabadGujaratIndia Depar.ment of Mathematics U V Patel College of EngineeringGanpat UniversityMahesanaIndia

This study examines the effect of heat pr.duction and r.diation absor.tion on the magnetohydr.dynamic Cassonfluidflow at the stagnation point in a por.us *** conver. the gr.up offluidflow equations,which ar. non-linear.par.ial differ.ntial equations with suitable boundar. constr.ints,into a set of non-linear.or.inar. differ.ntial equations using similar.ty *** homotopy analysis method(HAM)solves the conver.ed system of or.inar. differ.ntial *** dr.w gr.phs for.numer.us values of non-dimensional pa-r.meter. and tables of sur.ace dr.g for.e,r.tes of heat tr.nsfer.and mass tr.nsfer.to analyze the r.lationship between velocityfield,temper.tur.field,concentr.tionfield,and other.essential par.meter. involved in the *** have pr.ven that the Dufour.number.r.diation par.meter.and heat gener.tion par.meter.elevate thefluid temper.tur.,wher.as the magnetic par.meter.lower. *** Cassonfluid par.meter.buoyancy for.e par.meter.and mixed convection par.m-eter.all pr.motefluid movement thr.ughout *** pr.sented tabular.data allows us to see the tr.nd of heat and mass tr.nsfer.r.tes,as well as dr.g for.e r.tes,against impor.ant par.meter.,enhancing our.under.tanding of these r.tes.

关键词： Cassonfluid Magnetohydr.dynamics(MHD) Stagnation pointflow Ther.al r.diation Heat sour.e/sink Sor.t effect

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Stability Analysis and Efficiency Impr.vement of a Multi-conver.er.System Using Multi-objective Decision Making

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Chinese Jour.al of Electr.cal Engineer.ng 2023年第2期9卷 71-83页

作者： r.shmi patel.r.Chudamani Depar.ment of Electr.cal Engineer.ng Sardar Vallabhbhai National Institute of TechnologyIchchhanathAthawalinesSurat 395007India

Multi-conver.er.system is mainly used in advanced automotive *** conver.er. and inver.er. ar. taking par. in automotive systems to pr.vide differ.nt voltage levels in a multi-conver.er.*** involves constant voltage load(CVL),constant power.load(CPL)and other.*** CPL in such systems offer. negative impedance char.cter.stic and it cr.ates a destabilizing effect on the main *** effect of destabilization can be r.duced by incr.asing the CVL or.inser.ing par.sitic *** have been made by author. to impr.ve the stability by using par.sitics of differ.nt components such as switch,diode and *** of inser.ion of par.sitics including the ser.es equivalent r.sistance of the filter.capacitor.and var.ation in CVL on the per.or.ance of main conver.er.is mathematically analyzed and conflicting behavior.between system stability and efficiency is *** optimum solution between these two functions is obtained by using multi-objective decision making(MODM)by var.ing par.sitics of differ.nt components and *** attempt has been made to demonstr.te the effect of CVL load and the par.sitics on the stability and efficiency of the main conver.er.exper.mentally.

关键词： Multi-conver.er.system constant power.load(CPL) stability par.sitic elements efficiency and multi-objective decision making(MODM)

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Machine Lear.ing Techniques in Pr.dicting Hot Defor.ation Behavior.of Metallic Mater.als

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Computer.Modeling in Engineer.ng & Sciences 2025年第1期142卷 713-732页

作者： Petr.Opela Josef Walek Jar.mír.Kopecek Depar.ment of Metallur.ical Technologies Faculty of Materials Science and TechnologyVSB–Technical University of OstravaOstrava70800Czech Republic FZU—Institute of Physics of the Czech Academy of Sciences Prague18200Czech Republic

In engineer.ng pr.ctice,it is often necessar. to deter.ine functional r.lationships between dependent and independent *** r.lationships can be highly nonlinear.and classical r.gr.ssion appr.aches cannot always pr.vide sufficiently r.liable ***,Machine Lear.ing(ML)techniques,which offer.advanced r.gr.ssion tools to addr.ss complicated engineer.ng issues,have been developed and widely *** study investigates the selected ML techniques to evaluate their.suitability for.application in the hot defor.ation behavior.of metallic *** ML-based r.gr.ssion methods of Ar.ificial Neur.l Networ.s(ANNs),Suppor. Vector.Machine(SVM),Decision Tr.e r.gr.ssion(DTr.,and Gaussian Pr.cess r.gr.ssion(GPr.ar. applied to mathematically descr.be hot flow str.ss cur.e datasets acquir.d exper.mentally for.a medium-car.on *** the GPr.method has not been used for.such a r.gr.ssion task befor.,the r.sults showed that its per.or.ance is the most favor.ble and pr.ctically unr.valed;neither.the ANN method nor.the other.studied ML techniques pr.vide such pr.cise r.sults of the solved r.gr.ssion analysis.

关键词： Machine lear.ing Gaussian pr.cess r.gr.ssion ar.ificial neur.l networ.s suppor. vector.machine hot defor.ation behavior

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Heter.geneity of matur. oligodendr.cytes in the centr.l ner.ous system

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Neur.l r.gener.tion r.sear.h 2025年第5期20卷 1336-1349页

作者： Chao Weng Adam M.r.Gr.h Moein Yaqubi Qiao-Ling Cui Jo Anne Str.tton G.r.Wayne Moor. Jack P.Antel Neur.immunology Unit Montreal Neurological Institute-HospitalDepartment of Neurology and NeurosurgeryMcGill UniversityMontrealQCCanada Depar.ment of Neur.logy Renmin Hospital of Wuhan UniversityWuhanHubei ProvinceChina

Matur. oligodendr.cytes for. myelin sheaths that ar. cr.cial for.the insulation of axons and efficient signal tr.nsmission in the centr.l ner.ous *** evidence has challenged the classical view of the functionally static matur. oligodendr.cyte and r.vealed a gamut of dynamic functions such as the ability to modulate neur.nal cir.uitr. and pr.vide metabolic suppor. to *** the r.cognition of potential heter.geneity in matur. oligodendr.cyte function,a compr.hensive summar. of matur. oligodendr.cyte diver.ity is *** delve into ear.y 20th-centur. studies by r.ber.son and r.o-Hor.ega that laid the foundation for.the moder. identification of r.gional and mor.hological heter.geneity in matur. ***,r.cent mor.hologic and functional studies call into question the long-assumed homogeneity of matur. oligodendr.cyte function thr.ugh the identification of distinct subtypes with var.ing myelination ***,moder. molecular.investigations,employing techniques such as single cell/nucleus r.A sequencing,consistently unveil at least six matur. oligodendr.cyte subpopulations in the human centr.l ner.ous system that ar. highly tr.nscr.ptomically diver.e and var. with centr.l ner.ous system *** and disease r.lated matur. oligodendr.cyte var.ation denotes the impact of pathological conditions such as multiple scler.sis,Alzheimer.s disease,and psychiatr.c ***,caution is war.anted when subclassifying matur. oligodendr.cytes because of the simplification needed to make conclusions about cell identity fr.m tempor.lly confined *** studies lever.ging advanced techniques like spatial tr.nscr.ptomics and single-cell pr.teomics pr.mise a mor. nuanced under.tanding of matur. oligodendr.cyte *** r.sear.h avenues that pr.cisely evaluate matur. oligodendr.cyte heter.geneity with car. to under.tand the mitigating influence of species,sex,centr.l ner.ous system r.gion,age,and disease,

关键词： aging centr.l ner.ous system diseases electr.n micr.scopy heter.geneity immunohistochemistr. myelin sheath natur.l histor. neur.glia oligodendr.glia single-cell gene expr.ssion analysis

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Integr.ted lignocellulosic bior.finer.:Gateway for.pr.duction of second gener.tion ethanol and value added pr.ducts

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Jour.al of Bior.sour.es and Biopr.ducts 2021年第2期6卷 108-128页

作者： Amisha patel.Amita r.Shah Post Gr.duate Depar.ment of Biosciences Sardar Patel UniversitySatellite CampusVadtal RoadBakrol-388315GujaratIndia

An incr.asing demand for.ener.y and depleting petr.leum sour.es has elevated the need for.pr.ducing alter.ative r.newable *** to the pr.minence of lignocellulosic biomass as bio-r.newable and the most abundant r.sour.e on Ear.h,this cr.tical r.view pr.vides per.eptions into the potential of lignocellulosic biomass for.pr.duction of second gener.tion(2G)ethanol and value added pr.ducts in a bior.finer. *** efficient utilization of all thr.e components of lignocellulosic biomass(i.e.,cellulose,hemicellulose and lignin)would play a significant r.le in the economic viability of cellulosic *** pr.tr.atment method is the key to the success of bioconver.ion pr.cesses and gr.atly influences the economics of bior.finer. *** tools and pr.cess engineer.ng play pivotal r.les in development of integr.ted pr.cesses for.pr.duction of biofuels,biochemicals and biomater.als fr.m lignocellulosic ***,lignocellulosic bior.finer. has ample scopes,commer.ial pr.duction of biofuels and chemicals is still *** this context,this r.view entails concept of lignocellulose bior.finer.,latest developments in 2G ethanol pr.duction pr.cess,impor.ance and mar.et potential of 2G ethanol as r.newable fuel and value added chemicals,integr.tion of pr.cesses,challenges for.integr.ted pr.duction of fuel together.with value added chemicals and futur. dir.ctions.

关键词： Lignocellulosic biomass Bior.finer. Second gener.tion(2G)ethanol Value added pr.ducts

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