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The Treatment of partial-Thickness Burns with a Hydroconductive Wound Dressing: Clinical and Mechanistic Effects

Surgical Science 2013年第5期4卷 268-272页

作者： David J. Smith Rachel A. Karlnoski Ami patel C. Wayne Cruse Kimberly S. Brown Martin C. Robson Department of Surgery University of South Florida Tampa USA Florida Gulf-to-Bay Anesthesiology Associates LLC Tampa USA Tampa General Hospital Burn Center Tampa USA

Objectives: Edema in partial-thickness burn wounds can decrease tissue perfusion, increase tissue ischemia, and deepen the burn injury. We report the results of a clinical trial comparing the effectiveness of a hydro-conductive dressing to our standard burn dressing at removing edema fluid from partial-thickness burns and present the proposed mechanisms of action of the hydroconductive dressing. Methods: An internally controlled comparison of two wound dressings was performed on 10 patients with non-contiguous partial-thickness burns. Each patient served as his/her own control. One burn was treated with our standard burn dressing and the other with hydroconductive dressing. Dressings were weighed prior to application, removed at 24 and 48 hours, weighed, and new pre-weighed dressings applied. Weight gain of each dressing at 24 and 48 hours was determined. Statistics were applied using the Student’s paired T-test. The VAS pain scale was measured prior to, during, and after each dressing change. Results: At 24 hours, the hydroconductive dressing had increased 85.6% ± 29.3% in weight compared with 61.3% ± 32.7% for the control (p = 0.053). For the second 24 hour period, the respective numbers were statistically significantly different at 59.7% ± 23.4% vs. 34.2% ± 19.1% (p = 0.038). Averaging the weight gain over the two dressing periods demonstrated that the differences were highly statistically significant as the hydroconductive dressing increased in weight by 71.0% ± 20.3% compared with 44.5% ± 17.4% for the gauze dressing (p = 0.005). VAS scores revealed no statistical differences. Mechanisms of action included capillary, hydroconductive, and electrostatic actions. Conclusions: A hydroconductive dressing designed to draw off excessive wound fluid removes more wound edema fluid than standard burn gauze dressings.

关键词： Burn Wound Edema

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SnS thin films deposited by chemical bath deposition, dip coating and SILAR techniques

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Journal of Semiconductors 2016年第5期37卷 10-18页

作者： Sunil H.Chaki Mahesh D.Chaudhary M.p.Deshpande p.G.Department of physics Sardar Patel University

The SnS thin films were synthesized by chemical bath deposition （CBD）, dip coating and successive ionic layer adsorption and reaction （SILAR） techniques. In them, the CBD thin films were deposited at two tem- peratures： ambient and 70℃. The energy dispersive analysis of X-rays （EDAX）, X-ray diffraction （XRD）, Raman spectroscopy, scanning electron microscopy （SEM） and optical spectroscopy techniques were used to characterize the thin films. The electrical transport properties studies on the as-deposited thin films were done by measuring the I-V characteristics, DC electrical resistivity variation with temperature and the room temperature Hall effect. The obtained results are deliberated in this paper.

关键词： SnS thin films chemical bath deposition dip coating SILAR

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船舶电力推进、电力电子和海洋能源

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2015年

作者： (美)姆昆德 R.帕特尔(Mukund R. patel)

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用丝裂霉素C以穹隆和角膜缘为基底的小梁切除术的对比研究

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世界核心医学期刊文摘（眼科学分册） 2005年第10期1卷 27-28页

作者： Alwitry A. patel V. King A.W. 王大江 Eye Ear Nose and Throat Centre Qu eens Medical Centre Nottingham NG7 2UH United Kingdom

purpose: To compare the effectiveness of limbus-and fornixbased conjunctival flaps in patients undergoing trabeculectomy with mitomycin-C augmentation. Meth ods: A retrospective review of the records of 71 consecutive eyes of 59 patients who underwent trabeculectomy with mitomycin C. All the patients had at least 6 months of follow-up. The first 35 eyes underwent surgery with a limbal-based f lap, whereas all subsequent surgeries were by fornix-based procedures. Results: No significant difference was detected between the groups with regard to patien t demographics, preoperative visual field and intraocular pressure parameters, p ostoperative intraocular pressures at day 1, months 1, 3, and 6 postoperatively, need for intervention, need for supplementary glaucoma medication, and final vi sual acuity. There were four cases of overdrainage and hypotony in the limbal-b ased group, whereas none occurred in the fornix-based group. In all 83%percent of eyes in the limbal-based group achieved intraocular pressures off medicatio n of less than 18 mmHg, whereas 94%of the fornix based group obtained such IOp control. One patient in the limbal-based group developed late postoperative end ophthalmitis. Conclusion: Trabeculectomy with MMC augmentation is a safe and eff ective procedure for reduction of IOp and visual rehabilitation whether a fornix -or a limbal-based conjunctival flap is utilised. In this series, there was a greater risk of excessive drainage with subsequent hypotonous complications when surgery was undertaken by a limbal-based procedure.

关键词：小梁切除术结膜瓣低眼压眼内炎统计学特征药物治疗

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Experimental Shear Study on Reinforced High Strength Concrete Beams Made Using Blended Cement

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Journal of Architectural Environment & Structural Engineering Research 2022年第1期5卷 9-16页

作者： Brijesh Singh Vikas patel p.N.Ojha Amit Trivedi V.V.Arora National Council for Cement and Building Materials BallabgarhHaryanaIndia

With the increased application of High Strength Concrete(HSC)in construction and lack of proper guidelines for structural design in India,behavioral study of high strength concrete is an important aspect of *** on the behavior of HSC reinforced beams with concrete strength more than 60 Mpa has been carried out in the past and is still continuing to understand the structural behavior of HSC *** with the many benefits of the high strength concrete,the more brittle behavior is of concern which leads to sudden *** paper presents the behavior of reinforced HSC beams in shear with considering the effects of various factors like shear reinforcement ratio,longitudinal reinforcement ratio,l/d ratio(length to depth ratio),*** numbers Reinforced Concrete Beams of various sizes using concrete mix with three different w/c ratios(0.46,0.26 and 0.21)were cast for shear strength *** beams were tested in simply supported condition over two fixed steel pedestals with load rate of 0.2 mm/minute in displacement ***-point deflection was measured using LVDT.A comparative analysis of theoretical approaches of Euro code,extension of current IS code up to M90 and the experimental data was done to understand the behavior of *** capacities of beams without any factors of safety were used to assess the actual capacities and then was compared with the experimental capacity *** of this study can be used in the design of high strength concrete and will be more reliable in Indian continent as the regional materials and exposure conditions were considered.

关键词： High strength concrete Shear capacity Reinforced concrete beams Shear behaviour Span to depth ratio

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超声检查不明确的附件囊肿:卵巢癌的患病率和特征

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国际医学放射学杂志 2018年第4期 484-485页

作者： E.A.Sadowski V.paroder K.patel-Lippmann J.B.Robbins L.Barroilhet E.Maddox 朱静 Department of Radiology University of Wisconsin School of Medicine and Public HealthClinical Science Center

目的评估在医学中心进行盆腔超声(US)检查的妇女中不明确囊肿的发生率,确定其恶性率,并分析囊肿与病人的特征,用以预测恶性肿瘤可能。材料与方法该研究是2008年1月—2012年6月期间进行的一项多中心研究,对US发现的性质不明附件囊肿进行... 详细信息

目的评估在医学中心进行盆腔超声(US)检查的妇女中不明确囊肿的发生率,确定其恶性率,并分析囊肿与病人的特征,用以预测恶性肿瘤可能。材料与方法该研究是2008年1月—2012年6月期间进行的一项多中心研究,对US发现的性质不明附件囊肿进行随访(包括手术病理检查、影像学和/或临床检查)。根据现有文献中的定义,将性质不明确的囊肿分为1类(典型良性囊肿>5 cm)或2类(囊肿含有非血管的实性成分)。计算肿瘤和恶性肿瘤的发生率。评估与肿瘤、恶性肿瘤相关的病人特征和囊肿特征,采用卡方检验或Fisher确切概率检验计算分类变量,并采用t检验分析连续变量。利用逐步Logistic回归模型比较2种结果:(a)肿瘤(良性或恶性)和(b)恶性肿瘤。结果超声检查发现1 637例女性病人有附件囊肿,391例[年龄17～91岁,平均(41.8±13.5)岁]附件囊肿性质不明确。性质不明确附件囊肿的患病率为23.9%(391/1 637;95%CI:0.22～0.26)。对其中280例女性[年龄17～88岁,平均(42.9±14.1)岁]的303个不明确囊肿进行了充分随访。卵巢肿瘤(良、恶性)的发生率为24.8%(75/303,95%CI:0.20～0.30),恶性肿瘤的发生率为3.6%(11/303;95%CI:0.02～0.06)。卵巢肿瘤的比例在1类和2类囊肿之间有差异[17.5%,(1类143个囊肿中,肿瘤有25个,95%CI:0.12～0.25)与31.3%(2类160个囊肿中,肿瘤有50个;95%CI:0.24～0.39,p=0.001)]。恶性肿瘤的发生率在1、2类的比例分别为0(143个囊肿中有0个)与6.9%(160个囊肿中有11个;95%CI:0.03～0.12);在逐步逻辑回归分析中,囊肿内非血管实性成分的存在是恶性肿瘤的特征表现(优势比=2.83;p<0.000 1;95%CI:1.69～4.70)。结论对于性质不明确的附件囊肿,囊肿内非血管实性成分的存在是恶性肿瘤的特征表现。第2类囊肿与第1类囊肿相比,恶性风险更高。

关键词：超声检查恶性肿瘤患病率

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异氟烷复合caspase抑制剂减轻局部脑缺血损伤

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国外医学（麻醉学与复苏分册） 2004年第4期25卷 253-256页

作者： Satoki Inoue John C.Drummond Daniel p.Davis Daniel J.Cole piyush M.patel 马正良(译) 曾因明(审) Department of Anesthesiology Veterans Affairs Medical Center and University of CaliforniaSan Diego Department of Anesthesiology University of CaliforniaSan Diego Department of Emergency Medicine University of CaliforniaSan Diego Department of Anesthesiology The Mayo ClinicScottsdaleArizona 不详

背景:近来研究提示异氟烷的神经保护作用不是持续的.由细胞凋亡介导的神经元的延迟性死亡可导致梗死面积的逐渐增加.这些资料提示异氟醚可能不能抑制延迟性神经元死亡.除了异氟烷外,caspase抑制剂的神经细胞凋亡预防作用可以提供神经保... 详细信息

背景:近来研究提示异氟烷的神经保护作用不是持续的.由细胞凋亡介导的神经元的延迟性死亡可导致梗死面积的逐渐增加.这些资料提示异氟醚可能不能抑制延迟性神经元死亡.除了异氟烷外,caspase抑制剂的神经细胞凋亡预防作用可以提供神经保护作用.本研究的开展是决定在非特异性的caspase抑制剂z-VAD-fmk存在下异氟烷的神经保护作用是否更持久。

关键词：异氟烷复合Caspase抑制剂局部脑缺血损伤细胞凋亡介导神经元

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Comparison of open and closed hyperthermic intraperitoneal chemotherapy: Results from the United States hyperthermic intraperitoneal chemotherapy collaborative

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World Journal of Gastrointestinal Oncology 2020年第7期12卷 756-767页

作者： Jennifer L Leiting Jordan M Cloyd Ahmed Ahmed Keith Fournier Andrew J Lee Sophie Dessureault Seth Felder Jula Veerapong Joel M Baumgartner Callisia Clarke Harveshp Mogal Charles A Staley Mohammad Y Zaidi Sameer H patel Syed A Ahmad Ryan J Hendrix Laura Lambert Daniel E Abbott Courtney pokrzywa Mustafa Raoof Christopher J LaRocca Fabian M Johnston Jonathan Greer Travis E Grotz Division of Hepatobiliary and pancreas Surgery Mayo ClinicRochesterMN 55901United States Division of Surgical Oncology Department of SurgeryThe Ohio State University Wexner Medical CenterColumbusOH 43210United States Department of Surgical Oncology University of Texas MD Anderson Cancer CenterHoustonTX 77030United States Department of Gastrointestinal Oncology Moffitt Cancer CenterDepartment of Oncologic SciencesMorsani College of MedicineTampaFL 33612United States Division of Surgical Oncology Department of SurgeryUniversity of CaliforniaSan DiegoCA 92093United States Division of Surgical Oncology Department of SurgeryMedical College of WisconsinMilwaukeeWI 53226United States Division of Surgical Oncology Winship Cancer InstituteEmory UniversityAtlantaGA 30322United States Department of Surgery University of Cincinnati College of MedicineCincinnatiOH 45267United States Division of Surgical Oncology Department of SurgeryUniversity of Massachusetts Medical SchoolWorcesterMA 01655United States peritoneal Surface Malignancy program Section of Surgical Oncology Huntsman Cancer InstituteUniversity of UtahSalt Lake CityUT 84112United States Division of Surgical Oncology Department of SurgeryUniversity of WisconsinMadisonWI 53792United States Christopher La Rocca Division of Surgical OncologyDepartment of SurgeryCity of Hope National Medical CenterDuarteCA 91010United States Department of Surgery Johns Hopkins UniversityBaltimoreMD 21287United States

BACKGROUND Cytoreductive surgery(CRS)with hyperthermic intraperitoneal chemotherapy(HIpEC)for peritoneal carcinomatosis can be performed in two ways:Open or closed abdominal *** To evaluate the impact of HIpEC method on post-operative and long-term survival *** patients undergoing CRS with HIpEC from 2000-2017 were identified in the United States HIpEC collaborative ***-operative,recurrence,and overall survival outcomes were compared between those who received open vs closed *** Of the 1812 patients undergoing curative-intent CRS and HIpEC,372(21%)patients underwent open HIpEC and 1440(79%)underwent closed *** was no difference in re-operation or severe complications between the two *** HIpEC had higher rates of 90-d readmission while open HIpEC had a higher rate of 90-d *** multi-variable analysis,closed HIpEC technique was not a significant predictor for overall survival(hazards ratio:0.75,95%confidence interval:0.51-1.10,p=0.14)or recurrence-free survival(hazards ratio:1.39,95%confidence interval:1.00-1.93,p=0.05)in the entire *** findings remained consistent in the appendiceal and the colorectal *** In this multi-institutional analysis,the HIpEC method was not independently associated with relevant post-operative or long-term *** technique may be left to the discretion of the operating surgeon.

关键词： Mucinous appendiceal carcinoma Cytoreductive surgery Multi-institutional

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Emergency department visits:Why adults choose the emergency room over a primary care physician visit during regular office hours?

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World Journal of Emergency Medicine 2012年第2期3卷 91-97页

作者： Courtney Rocovich Trushnaa patel Department of Emergency Medicine Henry Ford Macomb Hospital

BACKGROUND:It has been estimated that up to one third of all emergency department(ED)visits may be"inappropriate"or *** that have been speculated to be associated with non-emergent use have been noted to include low socioeconomic status,lack of access to primary care,lack of insurance,convenience of"on demand care"and the patient's individual perception of their complaint *** objective of this study is to identify the reasons contributing to self-perceived non-emergent adult emergency department visits during primary care physician office hours of ***:This study was a single-center,descriptive study with *** questionnaire was collected from patients meeting exclusion/inclusion criteria who were triaged into an acute or fast track part of the emergency department during regular business hours on Monday through Friday,8:00 am-5:00 pm during the months of July 2011 and August *** data were categorical and summarized using counts and *** collected included patient demographics,information about the patient's primary care provider,and information about the emergency department visit in *** responses were compared among patients with visits considered to be non-emergent to those considered to be emergent by using individual chi-square ***:There were 262 patients available for the *** patients were grouped according to their perception of the severity of their *** half of the patients placed themselves into the non-emergent category(n=129),whereas the other half of the patients categorized themselves into the emergent group(n=131).There were statistically significant differences in marital status and employment status between the two *** was found that 61.5%of the non-emergent patients were single,while 58.3%of the emergent patients were *** the non-emergent group,59.7%were unemployed,but in the emergent group 60.3%were employed(p<0.05).Howe

关键词： Emergency department United States Overcrowding primary care physician

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CMp过滤技术的进展(英文)

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电子工业专用设备 2004年第6期33卷 26-35页

作者： Rakesh K. Singh Chintan patel Gregg Conner Hee Jun Yang Tim Towle Mykrolis Corporation 129 Concord Road Billerica MA 01821 USAMykrolis Corporation 129 Concord Road Billerica MA 01821 USAMykrolis Corporation 129 Concord Road Billerica MA 01821 USAMykrolis Corporation 129 Concord Road Billerica MA 01821 USAMykrolis Corporation 129 Concord Road Billerica MA 01821 USA

叙述了新一代CMp浆料的过滤工艺和方法。低比重和极小平均粒子尺寸的二氧化硅、氧化铝及氧化铈磨料在这些浆料中要求严格地控制在0.5μm,甚至对平均工作粒影响最小的更小粒子(例如0.03～0.2μm)以内。目前CMp浆料大量生产的加工目标将... 详细信息

叙述了新一代CMp浆料的过滤工艺和方法。低比重和极小平均粒子尺寸的二氧化硅、氧化铝及氧化铈磨料在这些浆料中要求严格地控制在0.5μm,甚至对平均工作粒影响最小的更小粒子(例如0.03～0.2μm)以内。目前CMp浆料大量生产的加工目标将积累的大于0.56及1.01μm的大颗粒减少了90%,在一次通过或现场使要求如此高的隔离过滤。根据浆料的特性能够采用的过滤方法如分级筛选密度、多薄层法、深褶媒质以及薄膜过滤法。CMp浆料过滤器的有效设计必须考虑到浆料磨损类型和成分、基本化学特性、LpCS、平均粒子尺寸分布、固体比重、粘性、磨料沉积速率、所需的粒子滞留、△p、流速稳定性和期望的过滤器寿命。由于磨料中相同的过滤器媒质性能根据浆料中磨料和添加剂的不同可能有很大的差别,新浆料过滤的最佳参数选顶实质上仍然保持了以实验为根据的方法。根据实验室表示特性、现场性能测试和过滤后的使用评价的数据,可以用作过滤最佳参数选定。由这些测试的典型结果现实,更新的氧化铈和氧化铝以及固有的二氧化硅CMp浆料的过滤有利于大颗粒的控制。

关键词： CHp浆料粒子尺寸控制浆料过滤

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