检索结果-南通市图书馆

Anterior capsule contraction syndrome: a successful multimodal therapeutic approach

在线全文

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2019年第8期12卷 1356-1358页

作者： Lisa Toto pasquale Viggiano Luca Vecchiarino Federica Evangelista Enrico Borrelli Leonardo Mastropasqua Ophthalmology Clinic Department of Medicine and Science of AgeingUniversity G. D’Annunzio Chieti-Pescara

Dear Editor,I am Dr. Lisa Toto, from Department of Medicine and Science of Ageing, University G. D’Annunzio ChietiPescara, Chieti, Italy. I write to present a case report of anterior capsule contraction syndrome(ACCS).

关键词： contraction syndrome approach

Orbital metastases in Italy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2015年第5期8卷 1018-1023页

作者： Patrizio Magliozzi Diego Strianese Paola Bonavolontà Mariantonia Ferrara pasquale Ruggiero Raffaella Carandente Giulio Bonavolontà Fausto Tranfa Department of Neuroscience Odontostomatological and Reproductive SciencesUniversity of Naples Federico Ⅱ

AIMTo describe a series of Italian patients with orbital metastasis focusing on the outcomes in relation to the different primary site of *** chart review of 93 patients with orbital metastasis collected in a tertiary referral centre in a period of 38y and review of *** of 93 patients, 52 were females and 41 were males. Median age at diagnosis was 51y (range 1 to 88y). The patients have been divided into four groups on the basis of the year of diagnosis. The frequency of recorded cases had decreased significantly (P<0.05) during the last 9.5y. Primary tumor site was breast in 36 cases (39%), kidney in 10 (11%), lung in 8 (9%), skin in 6 (6%); other sites were less frequent. In 16 case (17%) the primary tumor remained unknown. The most frequent clinical findings were proptosis (73%), limited ocular motility (55%), blepharoptosis (46%) and blurred vision (43%). The diagnosis were established by history, ocular and systemic evaluation, orbital imaging studies and open biopsy or fine needle aspiration biopsy (FNAB). Treatment included surgical excision, irradiation, chemotherapy, hormone therapy, or observation. Ninety-one percent of patients died of metastasis with an overall mean survival time (OMST) after the orbital diagnosis of ***, kidney and lung are the most frequent primary sites of cancer leading to an orbital metastasis. When the primary site is unknown, gastrointestinal tract should be carefully investigated. In the last decade a decrease in the frequency of orbital metastasis has been observed. Surgery provides a local palliation. Prognosis remains poor with a OMST of 13.5mo ranging from the 3mo in the lung cancer to 24mo in the kidney tumor.

关键词： orbital metastasis primary tumor survival time

Liver resection versus radiofrequency ablation in the treatment of cirrhotic patients with hepatocellular carcinoma

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2013年第3期12卷 270-277页

作者： Amilcare Parisi Jacopo Desiderio Stefano Trastulli Elisa Castellani Rosario pasquale Roberto Cirocchi Carlo Boselli Giuseppe Noya Department of Digestive Surgery and Liver Unit St. Maria Hospital Department of General and Oncologic Surgery University of Perugia St. Maria della Misericordia Hospital Department of General and Urgent Surgery University of Perugia

BACKGROUND: Hepatocellular carcinoma is the most common type of primary liver tumor and its incidence is increasing worldwide. The study aimed to compare patients subjected to liver resection or radiofrequency ablation. METHODS: One hundred and forty cirrhotic patients in stage A or B of Child-Pugh with single nodular or multinodular hepatocellular carcinoma were included in this retrospective study. Among them, 87 underwent surgical resection, and 53 underwent percutaneous radiofrequency ablation. Patient charac-teristics, survival, and recurrence-free survival were analyzed. RESULTS: Recurrence-free survival was longer in the resection group in comparison to the radiofrequency group with a median recurrence-free time of 36 versus 26 months, respectively (P=0.01, HR=1.52, 95% CI: 1.05-2.25). In the resection group, median survival was 46 months, with the 1-, 3- and 5-year survival rates of 89.7%, 72.4% and 40.2%. In the radiofrequency group, median survival was 32 months, with the 1-, 3- and 5-year survival rates of 83.0%, 43.4% and 22.6% (P<0.01). CONCLUSIONS: Surgical resection improves the overall survival and recurrence-free survival in comparison with radiofrequency ablation. New evidences are needed to define the real role of the percutaneous technique as an alternative to surgery.

关键词： hepatocellular carcinoma liver resection radiofrequency ablation

Multifaceted relationship between diabetes and kidney diseases:Beyond diabete

在线全文

学校读者我要写书评

暂无评论

World Journal of Diabetes 2023年第10期14卷 1450-1462页

作者： pasquale Esposito Daniela Picciotto Francesca Cappadona Francesca Costigliolo Elisa Russo Lucia Macciò Francesca Viazzi Department of Internal Medicine and Medical Specialties(DiMI) University of GenoaGenoa 16132Italy Unit of Nephrology Dialysis and TransplantationIRCCS Ospedale Policlinico San MartinoGenoa 16132Italy

Diabetes mellitus is one of the most common causes of chronic kidney *** involvement in patients with diabetes has a wide spectrum of clinical presentations ranging from asymptomatic to overt proteinuria and kidney *** development of kidney disease in diabetes is associated with structural changes in multiple kidney compartments,such as the vascular system and *** alterations include thickening of the glomerular basement membrane,loss of podocytes,and segmental mesangiolysis,which may lead to microaneurysms and the development of pathognomonic Kimmelstiel-Wilson *** lesions directly related to diabetes,awareness of the possible coexistence of nondiabetic kidney disease in patients with diabetes is *** nondiabetic lesions include focal segmental glomerulosclerosis,IgA nephropathy,and other primary or secondary renal *** diagnosis of these conditions is crucial in guiding clinical management and therapeutic ***,the relationship between diabetes and the kidney is bidirectional;thus,new-onset diabetes may also occur as a complication of the treatment in patients with renal ***,we review the complex and multifaceted correlation between diabetes and kidney diseases and discuss clinical presentation and course,differential diagnosis,and therapeutic opportunities offered by novel drugs.

关键词： Diabetes Diabetic kidney disease Nondiabetic kidney disease Biomarkers Glomerular disease Kidney biopsy Sodium-glucose cotransporter-2 inhibitors

Lamb-dip saturated-absorption cavity ring-down rovibrational molecular spectroscopy in the near-infrared

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Photonics Research 2022年第8期10卷 1803-1809页

作者： ROBERTO AIELLO VALENTINA DI SARNO MARIA GIULIA DELLI SANTI MAURIZIO DE ROSA IOLANDA RICCIARDI GIOVANNI GIUSFREDI PAOLO DE NATALE LUIGI SANTAMARIA pasquale MADDALONI Consiglio Nazionale delle Ricerche-Istituto Nazionale di Ottica Via Campi Flegrei 3480078 PozzuoliItaly Istituto Nazionale di Fisica Nucleare Sez.di NapoliComplesso Universitario di M.S.AngeloVia Cintia80126 NapoliItaly ppqSense S.r.l. Via Gattinella 2050013 Campi BisenzioItaly Consiglio Nazionale delle Ricerche-Istituto Nazionale di Ottica Largo E.Fermi 650125 FirenzeItaly Agenzia Spaziale Italiana Contrada Terlecchia75100 MateraItaly

The high-detection-sensitivity saturated-absorption cavity ring-down(SCAR)technique is extended to Lambdip spectroscopy of rovibrational molecular transitions in the near-infrared ***-comb-referenced sub-Doppler saturation measurements,performed on the acetylene(ν_(1)+ν_(3)+ν_(4)←ν_(4))R(14)e line at6562 cm^(-1),are analyzed by a SCAR global line profile fitting routine,based on a specially developed theoretical *** to a conventional cavity ring-down evaluation,our approach yields dip profiles with a linewidth freed from saturation broadening effects,reduced by 40%,and a signal-to-noise ratio increased by 90%.Ultimately,an overall(statistical and systematic)fractional uncertainty as low as 7×10^(-12)is achieved for the absolute line-center *** the same time,our method is also able to accurately infer the linear(nonsaturated)behavior of the gas absorption,providing Lamb-dip-based line strength measurements with a relative uncertainty of 0.5%.

关键词： saturated cavity absorption

Neurodegenerative diseases as proteinopathies-driven immune disorders

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2020年第5期15卷 850-856页

作者： Fausta Ciccocioppo Giuseppina Bologna Eva Ercolino Laura Pierdomenico pasquale Simeone Paola Lanuti Damiana Pieragostino Piero Del Boccio Marco Marchisio Sebastiano Miscia Department of Medicine and Aging Science University “G. d’Annunzio” of Chieti-PescaraChietiItaly Centre on Aging Sciences and Translational Medicine (Ce.S.I-MeT) University “G. d’Annunzio” of Chieti-PescaraChietiItaly Department of Medical Oral and Biotechnological SciencesUniversity “G. d’Annunzio” of Chieti-PescaraChietiItaly

In the pathophysiology of neurodegenerative disorders,the role of misfolded protein deposition leading to neurodegeneration has been primarily *** the last decade,however,it has been proposed a parallel involvement of innate immune activation,chronic inflammation and adaptive immunity in the neurodegeneration mechanisms triggered by *** insights in the neurodegenerative field strongly suggest a role for the immune system in the pathophysiology of neurodegenerative ***,the hypothesis underlining the modulation of the innate and the adaptive immune system in the events linked to brain deposition of misfolded proteins could open new perspectives in the setting of specific immunotherapeutic strategies for the treatment of neurodegenerative ***,we have reviewed the pathogenic hypothesis in neurodegenerative pathologies,underling the links between the deposition of misfolded protein mechanisms and the immune activation.

关键词： adaptive immunity choroid plexus immunotherapy innate immunity neurodegenerative diseases neuroinflammation proteinopathies

ddRAD sequencing-based genotyping for population structure analysis in cultivated tomato provides new insights into the genomic diversity of Mediterranean‘da serbo’type long shelf-life germplasm

在线全文

学校读者我要写书评

暂无评论

Horticulture Research 2020年第1期7卷 1047-1060页

作者： Salvatore Esposito Teodoro Cardi Gabriele Campanelli Sara Sestili María JoséDíez Salvador Soler Jaime Prohens pasquale Tripodi CREA Research Centre for Vegetable and Ornamental Crops Pontecagnano(SA)Italy CREA Research Centre for Vegetable and Ornamental Crops Monsampolo del Tronto(AP)TrontoItaly Instituto de Conservación y Mejora de la Agrodiversidad Valenciana Universitat Politècnica de València46022 ValenciaSpain

Double digest restriction-site associated sequencing(ddRAD-seq)is a flexible and cost-effective strategy for providing in-depth insights into the genetic architecture of germplasm *** this methodology,we investigated the genomic diversity of a panel of 288 diverse tomato(Solanum lycopersicum L.)accessions enriched in‘da serbo’(called‘de penjar’in Spain)long shelf life(LSL)materials(152 accessions)mostly originating from Italy and *** rest of the materials originate from different countries and include landraces for fresh consumption,elite cultivars,heirlooms,and breeding *** from their LSL trait,‘da serbo’landraces are of remarkable interest for their *** identified 32,799 high-quality SNPs,which were used for model ancestry population structure and non-parametric hierarchical *** genetic subgroups were revealed,clearly separating most‘da serbo’landraces,but also the Spanish germplasm,suggesting a subdivision of the population based on type and geographical *** disequilibrium(LD)in the collection decayed very rapidly within<5 *** then investigated SNPs showing contrasted minor frequency allele(MAF)in‘da serbo’materials,resulting in the identification of high frequencies in this germplasm of several mutations in genes related to stress tolerance and fruit maturation such as CTR1 and ***,a mini-core collection of 58 accessions encompassing most of the diversity was selected for further exploitation of key *** findings suggest the presence of a genetic footprint of the‘da serbo’germplasm selected in the Mediterranean ***,we provide novel insights on LSL‘da serbo’germplasm as a promising source of alleles for tolerance to stresses.

关键词： germplasm breeding shelf

Building a European geothermal information network using a distributed e-Infrastructure

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Digital Earth 2016年第5期9卷 499-519页

作者： Eugenio Trumpy Gianpaolo Coro Adele Manzella pasquale Pagano Donatella Castelli Philippe Calcagno Annamaria Nador Thorvaldur Bragasson Sylvain Grellet Gunter Siddiqi aIstituto di Geoscienze e Georisorse(IGG) National Research Council of Italyvia Moruzzi 1PisaItaly Istituto di Scienza e Tecnologie dell’Informazione‘A.Faedo’(ISTI) National Research Council of Italyvia Moruzzi 1PisaItaly Bureau de Recherches Géologiques et Minières(BRGM) OrleansFrance Magyar Foldtaniès Geofizikai Intèzet(MFGI) BudapestHungary Orkustofnun(OS) ReykjavikIceland Swiss Federal Office of Energy(SFOE) BernSwitzerland

Geothermal data are published using different IT services,formats and content representations,and can refer to both regional and global scale *** stakeholders search for information with different aims.E-Infrastructures are collaborative platforms that address this diversity of aims and data *** this paper,we present a prototype for a European Geothermal Information Platform that uses INSPIRE recommendations and an e-Infrastructure(D4Science)to collect,aggregate and share data sets from different European data contributors,thus enabling stakeholders to retrieve and process a large amount of *** system merges segmented and national realities into one common *** demonstrate our approach by describing a platform that collects data from Italian,French,Hungarian,Swiss and Icelandic geothermal data providers.

关键词： Geothermal documents distributed data geothermal spatial data infrastructure e-Infrastructures D4Science hybrid data infrastructures

Call for joint international actions to improve scientific understanding and address soil erosion and riverine sediment issues in mountainous regions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Soil and Water Conservation Research 2023年第3期11卷 586-588页

作者： Fan Zhang Baoyuan Liu Liping Zhu Richard Cruse Dongfeng Li Panos Panagos pasquale Borrelli Yakov Kuzyakov Shaoshan An State Key Laboratory of Tibetan Plateau Earth System Environment and Resources(TPESER)Institute of Tibetan Plateau ResearchChinese Academy of SciencesBeijingChina Beijing Normal University BeijingChina Agronomy Department at Iowa State University AmesIAUnited States Department of Geography National University of SingaporeKent RidgeSingapore European Commission Joint Research CentreIspraItaly Department of Environmental Sciences Environmental GeosciencesUniversity of BaselBaselSwitzerland Department of Science Roma Tre UniversityRomeItaly Department of Soil Science of Temperate Ecosystems Department of Agricultural Soil ScienceGeorg-August-University of GottingenGermany Research Center of Water and Soil Conservation and Ecological Environment Chinese Academy of Sciences&Ministry of EducationYanglingShaanxiChina

During the International Workshop on Soil Erosion and Riverine Sediment in Mountainous Regions held in November 2022,scientists from many countries shared their state-of-the-art knowledge and brainstormed to improve scientific understanding for coping with climate change and anthropogenic *** summarized in this discussion includes proposed key scientific questions and suggested joint actions to reduce soil erosion and riverine sediment problems in mountainous regions.

关键词： soil mountainous summarized