检索结果-南通市图书馆

Neuro-symbolic approaches in artificial intelligence

在线全文

学校读者我要写书评

暂无评论

National Science Review 2022年第6期9卷 35-37页

作者： pascal Hitzler Aaron Eberhart Monireh Ebrahimi md Kamruzzaman Sarker Lu Zhou Department of Computer Science Kansas State University Center for Open Source Data and AI Technologies (CODAIT) IBM Watson Department of Computing Sciences University of Hartford

Neuro-symbolic artificial intelligence refers to a field of research and applications that combines machine learning methods based on artificial neural networks, such as deep learning, with symbolic approaches to computing and artificial intelligence(AI), as can be found for example in the AI subfield of knowledge representation and reasoning.

关键词： artificial intelligence deep learning knowledge representation and reasoning neuro-symbolic integration

含二硫化硒洗发水对中-重度头皮脂溢性皮炎外用糖皮质激素/水杨酸治疗后的疗效维持作用

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

中华皮肤科杂志 2024年第5期57卷 483-484页

作者： Philippe Massiot pascal reygagne Corinne Chagnoleau Leila Kanoun-Copy Florence Pouradier Geneviève Loussouarn Catherine Queille-Roussel Hussein Jouni Delphine Kerob L'Oréal Research and Innovation Saint-Ouen France. Centre Sabouraud Hôpital Saint-Louis 1 avenue Claude-Vellefaux 75010 Paris France. CPCAD Hôpital l'Archet Nice France. L'Oréal Research and Innovation Aulnay-sous-Bois France. Cosmetic Active International Levallois-Perret France.

脂溢性皮炎是一种慢性炎症性皮肤病,好发于头皮、面部和躯干等皮脂腺分布丰富的部位。头皮脂溢性皮炎主要表现为红斑和片状鳞屑,程度从轻度鳞屑到弥漫性大片黏着性鳞屑不等,伴有明显的瘙痒,并容易反复发作。目前认为脂溢性皮炎的发生与... 详细信息

脂溢性皮炎是一种慢性炎症性皮肤病,好发于头皮、面部和躯干等皮脂腺分布丰富的部位。头皮脂溢性皮炎主要表现为红斑和片状鳞屑,程度从轻度鳞屑到弥漫性大片黏着性鳞屑不等,伴有明显的瘙痒,并容易反复发作。目前认为脂溢性皮炎的发生与亲脂性马拉色菌定植增加以及遗传、环境和全身健康状况等因素相关,上述因素共同导致皮脂腺代谢活动异常、皮脂成分改变、表皮屏障功能障碍,最终加重炎症反应。

关键词：头皮脂溢性皮炎二硫化硒洗发水亲脂性炎症反应马拉色菌皮脂腺黏着性

Human iPSC-derived iMSCs improve bone regeneration in mini-pigs

在线全文

学校读者我要写书评

暂无评论

Bone Research 2019年第4期7卷 399-409页

作者： pascal Jungbluth Lucas-Sebastian Spitzhorn Jan Grassmann Stephan Tanner David Latz md Shaifur Rahman Martina Bohndorf Wasco Wruck Martin Sager Vera Grotheer Patric Kropil Mohssen Hakimi Joachim Windolf Johannes Schneppendahl James Adjaye Department of Trauma and Hand Surgery Heinrich Heine University Hospital DüsseldorfMoorenstr.540225 DüsseldorfGermany Institute for Stem Cell Research and Regenerative Medicine Medical FacultyHeinrich Heine UniversityDüsseldorfMoorenstr.540225 DüsseldorfGermany Animal Research Institute Heinrich Heine UniversityDüsseldorfMoorenstr.540225 DüsseldorfGermany Department of Diagnostic and Interventional Radiology Medical FacultyHeinrich Heine UniversityDüsseldorfMoorenstr.540225 DüsseldorfGermany Vivantes Klinikum Am Urban Dieffenbachstraβe 110967 BerlinGermany

Autologous bone marrow concentrate(BMC)and mesenchymal stem cells(MSCs)have beneficial effects on the healing of bone *** address the shortcomings associated with the use of primary MSCs,induced pluripotent stem cell(iPSC)-derived MSCs(iMSCs)have been proposed as an *** aim of this study was to investigate the bone regeneration potential of human iMSCs combined with calcium phosphate granules(CPG)in critical-size defects in the proximal tibias of mini-pigs in the early phase of bone healing compared to that of a previously reported autograft treatment and treatment with a composite made of either a combination of autologous BMC and CPG or CPG *** were derived from iPSCs originating from human fetal foreskin fibroblasts(HFFs).They were able to differentiate into osteoblasts in vitro,express a plethora of bone morphogenic proteins(BMPs)and secrete paracrine signaling-associated cytokines such as PDGF-AA and *** and histomorphometrically,HFF-iMSC+CPG transplantation resulted in significantly better osseous consolidation than the transplantation of CPG alone and produced no significantly different outcomes compared to the transplantation of autologous BMC+CPG after 6 *** results of this translational study imply that iMSCs represent a valuable future treatment option for load-bearing bone defects in humans.

关键词： healing alone treatment

在线全文

学校读者我要写书评

暂无评论

脑微出血：使用定量磁敏感成像进行负担评估

中国医疗设备 2012年第4期27卷 1-8页

作者： Tian Liu, PhD Kdshna Surapaneni, md, MPH Min Lou, md Liuquan Cheng, md pascal Spincemaille, PhD Yi Wang, PhD 康奈尔大学生物医学工程系美国纽约威尔康奈尔医学院放射学系美国纽约哥伦比亚大学放射学系美国纽约浙江大学医学院第二附属医院神经科中国浙江中国人民解放军总医院放射科中国北京庆熙大学生物工程学系韩国首尔华东师范大学上海市磁共振重点实验室中国上海

目的评估定量磁敏感成像（QSM）在减少标准磁共振成像序列测量脑微出血负担不一致性的作用。材料与方法本研究遵守《健康保险可携带性及责任法案》（HIPAA）并获得公共审查委员会批准。从178例连续的患者中选出10例（5．6％），这178例... 详细信息

目的评估定量磁敏感成像（QSM）在减少标准磁共振成像序列测量脑微出血负担不一致性的作用。材料与方法本研究遵守《健康保险可携带性及责任法案》（HIPAA）并获得公共审查委员会批准。从178例连续的患者中选出10例（5．6％），这178例患者均在3．0T多重回波梯度回波成像检查中诊断为疑似中风且在T2＊加权成像下显示有脑微出血现象。通过形态学偶极子反演方法（MEDI）中的幅度和相位绘制出各个回波时闻下的QSM图像。脑微出血的大小由两名神经放射学专家通过不同回波时间下的QSM图像、T2＊加权图像、磁敏感加权（SW）图像以及R2＊图像测得。脑微出血区域的总磁敏感度也通过QSM图像评估出来。用t检验和—险验对测量误差进行了评估，P〈0．05为差异有统计学意义。结果当回波时间从约20ms增加至约40ms时，QSM图像、T2＊加权图像以及SW图像下可测量的脑微出血量平均因子（x±s）分别为1．49±0．86、1．64±0．84、2．30±1．20，P〈0．01。然而，QSM方法的总磁敏感度并没有随着回波时间的变化发生明显改变（P=0．31），且变化程度明显小于任意脑微出血量的增加程度（P〈0．01）。结论使用QSM方法测量脑微出血总磁敏感度是独立于回波时间的物理属性。

关键词：磁敏感成像脑微出血评估负担梯度回波成像加权图像回波时间测量误差

The GeoLink knowledge graph

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Big Earth Data 2018年第2期2卷 131-143页

作者： Michelle Cheatham Adila Krisnadhi Reihaneh Amini pascal Hitzler Krzysztof Janowicz Adam Shepherd Tom Narock Matt Jones Peng Ji Department of Computer Science and Engineering Wright State UniversityDaytonOHUSA Department of Computer Science Universitas IndonesiaDepokIndonesia Geography Department University of California at Santa BarbaraSanta BarbaraCAUSA Woods Hole Oceanographic Institution Woods HoleMAUSA Mathematics/Physics Department Notre Dame of Maryland UniversityBaltimoreMDUSA National Center for Ecological Analysis and Synthesis Santa BarbaraCAUSA Lamont-Doherty Earth Observatory Columbia UniversityPalisadesNYUSA

GeoLink has leveraged linked data principles to create a dataset that allows users to seamlessly query and reason over some of the most prominent geoscience metadata repositories in the United *** GeoLink dataset includes such diverse information as port calls made by oceanographic cruises,physical sample meta-data,research project funding and staffing,and authorship of technical *** data has been published according to best practices for linked data and is publicly available via a SPARQL Protocol and RDF Query Language(SPARQL)end point that at present contains more than 45 million Resource Description Framework(RDF)triples together with a collection of ontologies and geo-visualization *** article describes the geoscience datasets,the modeling and publication process,and current uses of the *** focus is on providing enough detail to enable researchers,application developers and others who wish to lever-age the GeoLink data in their own work to do so.

关键词： Geoscience data oceanographic data knowledge graph linked data ontology

奥拉帕利用于胚系BRCA基因突变型转移性胰腺癌一线铂类化疗后的维持治疗

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

肝胆外科杂志 2020年第3期28卷 166-166页

作者：濮天(摘译) 赵义军(审校) Talia Golan pascal Hammel From the Oncology Institute Sheba Medical Center Tel Aviv University Tel Aviv Israel (T.G.) Hôpital Beaujon (Assistance Publique-Hôpitaux de Paris) Clichy and University Paris VII Paris (P.H.) IRCCS Ospedale San Raffaele Scientific Institute Milan (M.R.) Azienda Ospedaliera Universitaria Integrata Verona Verona (G.T.) and Fondazione Policlinico Universitario Gemelli IRCCS Rome (G.T.) - all in Italy University Hospitals Gasthuisberg and KU Leuven Leuven Belgium (E.V.C.) Vall d'Hebron University Hospital and Vall d'Hebron Institute of Oncology Barcelona (T.M.) Fox Chase Cancer Center Philadelphia (M.J.H.) Samsung Medical Center Sungkyunkwan University School of Medicine (J.-O.P.) and Seoul National University Hospital Cancer Research Institute Seoul National University College of Medicine (D.-Y.O.) - both in Seoul South Korea University College London Cancer Institute London (D.H.) and AstraZeneca Cambridge (D.M.) - both in the United Kingdom Asklepios Tumorzentrum Hamburg Asklepios Klinik Altona Hamburg (D.A.) St. Josef-Hospital Ruhr University Bochum Bochum (A.R.-S.) and Klinikum rechts der Isar Department of Internal Medicine II Technische Universität München Munich (H.A.) - all in Germany Memorial Sloan Kettering Cancer Center New York (E.M.O.) AstraZeneca Gaithersburg MD (K.Y.C. G.Y.L.) Merck Kenilworth NJ (K.S.) and the University of Chicago Chicago (H.L.K.).

胰腺癌的分子靶向治疗探索之路充满挑战且收获甚微,直至本次POLO (Pancreas Cancer Olaparib Ongoing)研究结果发表在新英格兰杂志。奥拉帕利(olaparib)也被NCCN指南推荐用来治疗BRCA突变型胰腺癌。BRCA基因突变除了与卵巢癌及乳腺癌发... 详细信息

胰腺癌的分子靶向治疗探索之路充满挑战且收获甚微,直至本次POLO (Pancreas Cancer Olaparib Ongoing)研究结果发表在新英格兰杂志。奥拉帕利(olaparib)也被NCCN指南推荐用来治疗BRCA突变型胰腺癌。BRCA基因突变除了与卵巢癌及乳腺癌发病有关外,还可导致胰腺癌的发病风险也明显增加。

关键词：分子靶向治疗维持治疗发病风险新英格兰胰腺癌铂类化疗奥拉卵巢癌

Redefining pandemic preparedness:Multidisciplinary insights from the CERP modelling workshop in infectious diseases,workshop report

在线全文

学校读者我要写书评

暂无评论

Infectious Disease Modelling 2024年第2期9卷 501-518页

作者： Marta C.Nunes Edward Thommes Holger Fröhlich Antoine Flahault Julien Arino Marc Baguelin Matthew Biggerstaff Gaston Bizel-Bizellot Rebecca Borchering Giacomo Cacciapaglia Simon Cauchemez Alex Barbier-Chebbah Carsten Claussen Christine Choirat Monica Cojocaru Catherine Commaille-Chapus Chitin Hon Jude Kong Nicolas Lambert Katharina B.Lauer Thorsten Lehr Cédric Mahe Vincent Marechal Adel Mebarki Seyed Moghadas Rene Niehus Lulla Opatowski Francesco Parino Gery Pruvost Andreas Schuppert Rodolphe Thiébaut Andrea Thomas-Bachli Cecile Viboud Jianhong Wu pascal Crépey Laurent Coudeville Center of Excellence in Respiratory Pathogens(CERP) Hospices Civils de Lyon(HCL)and Centre International de Recherche en Infectiologie(CIRI)Équipe SantéPubliqueÉpidémiologie etÉcologieÉvolutive des Maladies Infectieuses(PHE3ID)Inserm U1111CNRS UMR5308ENS de LyonUniversitéClaude Bernard Lyon 1LyonFrance South African Medical Research Council Vaccines&Infectious Diseases Analytics Research UnitFaculty of Health SciencesUniversity of the WitwatersrandJohannesburgSouth Africa New Products and Innovation(NPI) Sanofi Vaccines(Global)TorontoOntarioCanada Department of Mathematics and Statistics University of GuelphGuelphOntarioCanada Fraunhofer Institute for Algorithms and Scientific Computing(SCAI) Department of BioinformaticsSchloss BirlinghovenSankt AugustinGermany University of Bonn Bonn-Aachen International Center for IT(b-it)BonnGermany Institute of Global Health Faculty of MedicineUniversity of GenevaGenevaSwitzerland and Swiss School of Public HealthZürichSwitzerland Department of Mathematics University of ManitobaWinnipegManitobaCanada MRC Centre for Global Infectious Disease Analysis School of Public HealthImperial College LondonLondonUK Centre for Mathematical Modelling of Infectious Diseases Department of Infectious Disease EpidemiologyLondon School of Hygiene&Tropical MedicineLondonUK National Center for Immunization and Respiratory Diseases(NCIRD) US Centers for Disease Control and Prevention(CDC)AtlantaGAUSA Departement of Computational Biology Departement of Global HealthInstitut PasteurParisFrance Institut de Physique des Deux Infinis de Lyon(IP2I) UMR5822IN2P3/CNRSUniversitéClaude Bernard Lyon 1VilleurbanneFrance Mathematical Modelling of Infectious Diseases Unit Institut PasteurUniversitéParis CitéUMR2000 CNRSParisFrance Decision and Bayesian Computation Institut PasteurUniversitéParis CitéCNRS UMR 3571France Fraunhofer-Institute for Translational Medicine and Pharmacology HamburgGermany Institute of Global Health Faculty of MedicineUniversity of

In July 2023,the Center of Excellence in Respiratory Pathogens organized a two-day workshop on infectious diseases modelling and the lessons learnt from the Covid-19 *** report summarizes the rich discussions that occurred during the *** workshop participants discussed multisource data integration and highlighted the benefits of combining traditional surveillance with more novel data sources like mobility data,social media,and wastewater *** advancements were noted in the development of predictive models,with examples from various countries showcasing the use of machine learning and artificial intelligence in detecting and monitoring disease *** role of open collaboration between various stakeholders in modelling was stressed,advocating for the continuation of such partnerships beyond the pandemic.A major gap identified was the absence of a common international framework for data sharing,which is crucial for global pandemic ***,the workshop underscored the need for robust,adaptable modelling frameworks and the integration of different data sources and collaboration across sectors,as key elements in enhancing future pandemic response and preparedness.

关键词： Modelling Covid-19 Infectious diseases Pandemic preparedness Workshop

Fluctuating temperature modifies heat-mortality association around the globe

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Innovation 2022年第2期3卷 65-72页

作者： Yao Wu Bo Wen Shanshan Li Antonio Gasparrini Shilu Tong Ala Overcenco Ales Urban Alexandra Schneider Alireza Entezari Ana Maria Vicedo-Cabrera Antonella Zanobetti Antonis Analitis Ariana Zeka Aurelio Tobias Barrak Alahmad Ben Armstrong Bertil Forsberg CarmenÍñiguez Caroline Ameling César De la Cruz Valencia ChristoferÅström Danny Houthuijs Do Van Dung Dominic Royé Ene Indermitte Eric Lavigne Fatemeh Mayvaneh Fiorella Acquaotta Francesca de’Donato Francesco Sera Gabriel Carrasco-Escobar Haidong Kan Hans Orru Ho Kim Iulian-Horia Holobaca Jan Kyselý Joana Madureira Joel Schwartz Klea Katsouyanni Magali Hurtado-Diaz Martina SRagettli Masahiro Hashizume Mathilde pascal Micheline de Sousa Zanotti Stagliorio Coélho Noah Scovronick Paola Michelozzi Patrick Goodman Paulo Hilario Nascimento Saldiva Rosana Abrutzky Samuel Osorio Tran Ngoc Dang Valentina Colistro Veronika Huber Whanhee Lee Xerxes Seposo Yasushi Honda Michelle L.Bell Yuming Guo Department of Epidemiology and Preventive Medicine School of Public Health and Preventive MedicineMonash UniversityMelbourne 3004Australia Climate Air Quality Research UnitSchool of Public Health and Preventive MedicineMonash UniversityMelbourne 3004Australia Department of Public Health Environments and SocietyLondon School of Hygiene&Tropical MedicineLondon WC1E 7HTUK Centre for Statistical Methodology London School of Hygiene&Tropical MedicineLondon WC1E 7HTUK Centre on Climate Change&Planetary Health London School of Hygiene&Tropical MedicineLondon WC1E 7HTUK Shanghai Children’s Medical Centre Shanghai Jiao Tong UniversityShanghai 200025China School of Public Health Institute of Environment and Human HealthAnhui Medical UniversityHefei 230032China Center for Global Health Nanjing Medical UniversityNanjing 211166China School of Public Health and Social Work Queensland University of TechnologyBrisbane 4000Australia National Agency for Public Health of the Ministry of Health Labour and Social Protection of the Republic of MoldovaChisinau MD-2009Republic of Moldova Institute of Atmospheric Physics Czech Academy of SciencesPrague 14100Czech Republic Faculty of Environmental Sciences Czech University of Life SciencesPrague 16500Czech Republic Institute of Epidemiology Helmholtz Zentrum M€unchen-German Research Center for Environmental HealthNeuherberg 85747Germany Faculty of Geography and Environmental Sciences Hakim Sabzevari UniversitySabzevar ***Iran Institute of Social and Preventive Medicine University of BernBern 3012Switzerland Oeschger Center for Climate Change Research University of BernBern 3012Switzerland Department of Environmental Health Harvard T.H.Chan School of Public HealthHarvard UniversityBostonMA 02115USA Department of Hygiene Epidemiology and Medical StatisticsNational and Kapodistrian University of AthensAthens 11527Greece Institute for Environment Healthand SocietiesBrunel University LondonLondon UB83PNUK Institute of Environmental Assessment and

Studies have investigated the effects of heat and temperature variability(TV)on ***,few assessed whether TV modifies the heat-mortality *** on daily temperature and mortality in the warm season were collected from 717 locations across 36 *** was calculated as the standard deviation of the average of the same and previous days’minimum and maximum temperatures.

关键词： deviation modif heat

An Earth-mass planet in a time of COVID-19:KMT-2020-BLG-0414Lb

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2021年第9期21卷 243-261页

作者： Weicheng Zang Cheongho Han Iona Kondo Jennifer C.Yee Chung-Uk Lee Andrew Gould Shude Mao Leandro de Almeida Yossi Shvartzvald Xiangyu Zhang Michael D.Albrow Sun-Ju Chung Kyu-Ha Hwang Youn Kil Jung Yoon-Hyun Ryu In-Gu Shin Sang-Mok Cha Dong-Jin Kim Hyoun-Woo Kim Seung-Lee Kim Dong-Joo Lee Yongseok Lee Byeong-Gon Park Richard W.Pogge John Drummond Thiam-Guan Tan JoséDias do Nascimento Júnior Dan Maoz Matthew T.Penny Wei Zhu Ian A.Bond Fumio Abe Richard Barry David P.Bennett Aparna Bhattacharya Martin Donachie Hirosane Fujii Akihiko Fukui Yuki Hirao Yoshitaka Itow Rintaro Kirikawa Naoki Koshimoto Man Cheung Alex Li Yutaka Matsubara Yasushi Muraki Shota Miyazaki Greg Olmschenk Clément Ranc Nicholas J.Rattenbury Yuki Satoh Hikaru Shoji Stela Ishitani Silva Takahiro Sumi Daisuke Suzuki Yuzuru Tanaka Paul J.Tristram Tsubasa Yamawaki Atsunori Yonehara Andreea Petric Todd Burdullis pascal Fouqué Department of Astronomy Tsinghua UniversityBeijing 100084China Department of Physics Chungbuk National UniversityCheongju 28644Republic of Korea Department of Earth and Space Science Graduate School of ScienceOsaka UniversityToyonakaOsaka 560-0043Japan Center for Astrophysics j Harvard&Smithsonian 60 Garden St.CambridgeMA 02138USA Korea Astronomy and Space Science Institute Daejon 34055Republic of Korea University of Science and Technology Korea(UST)217 Gajeong-ro Yuseong-guDaejeon 34113Republic of Korea Max-Planck-Institute for Astronomy Königstuhl 1769117 HeidelbergGermany Department of Astronomy Ohio State University140 W.18th Ave.ColumbusOH 43210USA National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China Universidade Federal do Rio Grande do Norte(UFRN) Departamento de F´1sica59078-970NatalRNBrazil Department of Particle Physics and Astrophysics Weizmann Institute of ScienceRehovot 76100Israel University of Canterbury Department of Physics and AstronomyPrivate Bag 4800Christchurch 8020New Zealand School of Space Research Kyung Hee UniversityYonginKyeonggi 17104Republic of Korea Possum Observatory PatutahiGisbourneNew Zealand Perth Exoplanet Survey Telescope PerthAustralia School of Physics and Astronomy Tel-Aviv UniversityTel-Aviv 6997801Israel Department of Physics and Astronomy Louisiana State UniversityBaton RougeLA 70803 USA Canadian Institute for Theoretical Astrophysics University of Toronto60 St George StreetTorontoON M5S 3H8Canada Institute of Natural and Mathematical Sciences Massey UniversityAuckland 0745New Zealand Institute for Space-Earth Environmental Research Nagoya UniversityNagoya 464-8601Japan Code 667 NASA Goddard Space Flight CenterGreenbeltMD 20771USA Department of Astronomy University of MarylandCollege ParkMD 20742USA Department of Physics University of AucklandPrivate Bag 92019AucklandNew Zealand Department of Earth and Planetary Science Graduate School of ScienceThe University of Tokyo7-3-1 Hongo

We report the discovery of KMT-2020-BLG-0414 Lb,with a planet-to-host mass ratio q2=0.9-1.2×10-5=3-4 q⊕at 1σ,which is the lowest mass-ratio microlensing planet to *** with two other recent discoveries(4?q/q⊕?6),it fills out the previous empty sector at the bottom of the triangular(log s,log q)diagram,where s is the planet-host separation in units of the angular Einstein radiusθ***,these discoveries call into question the existence,or at least the strength,of the break in the mass-ratio function that was previously suggested to account for the paucity of very low-q *** to the extreme magnification of the event,Amax~1450 for the underlying single-lens event,its light curve revealed a second companion with q3~0.05 and|log s3|~1,i.e.,a factor~10 closer to or farther from the host in *** measurements of the microlens parallaxπE and the angular Einstein radiusθE allow estimates of the host,planet and second companion masses,(M1,M2,M3)~(0.3 M⊙,1.0 M⊕,17 MJ),the planet and second companion projected separations,(a⊥,2,a⊥,3)~(1.5,0.15 or 15)au,and system distance DL~1 *** lens could account for most or all of the blended light(I~19.3)and so can be studied immediately with high-resolution photometric and spectroscopic observations that can further clarify the nature of the *** planet was found as part of a new program of high-cadence follow-up observations of high-magnification *** detection of this planet,despite the considerable difficulties imposed by COVID-19(two KMT sites and OGLE were shut down),illustrates the potential utility of this program.

关键词： gravitational lensing:micro