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Is Routine Bilateral Neck Dissection Absolutely Necessary in the Management of N0 CT Negative Neck in Patients with T4 Laryngeal Head and Neck Carcinoma?

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Journal of Cancer Therapy 2011年第3期2卷 322-324页

作者： Didier Dequanter Delphine Geukens Jean-Marie Bailly Mohammad Shahla pascal paulus Philippe Lothaire 不详

Objectives: Elective neck treatment of clinically N0 patients in patients with head and neck carcinomas is widely accepted as a standard approach. However, the issue whether elective neck treatment should routinely be directed on both sides of the neck is still controversial. The present study is aimed at determining whether T4 staged head and neck carcinomas required bilateral neck dissection in the management clinically No necks especially CT negative cervical nodes. Methods: We performed a retrospective analysis of patients with advanced head and neck disease who received bilateral neck dissection. All the patients had curative surgery as their initial treatment for the primary tumor and the neck. Results: All the 28 consecutive patients had T4 staged primary laryngeal cancer. Patients with clinically and radiologically N+ disease had invaded lymph node metastases in all cases. Patients staged clinically and radiologically N0 had no invaded cervical lymph nodes found by pathologic examination. Patients staged clinically N0 and radiologically N+ had invaded cervical lymph nodes in 8/12 cases and in 50% (4/8) of the cases bilaterally. Conclusion: This study showed the importance on adequate clinical and radiological staging. By patients with advanced disease clinically and radiologically N0, bilateral neck dissection should not be necessary. But in patients radiologically N+, routine bilateral neck dissection is beneficial.

关键词： Advanced Head And Neck Cancer Bilateral Neck Dissection Radiological Evaluation

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Innovations in Retinal Laser Technology

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Optics and Photonics Journal 2018年第6期8卷 173-186页

作者： Xinyi Xie Qinghuai Liu Yannis M. paulus Department of Biomedical Engineering University of Michigan Ann Arbor MI USA Department of Ophthalmology The First Affiliated Hospital of Nanjing Medical University Nanjing China Department of Ophthalmology and Visual Sciences University of Michigan Ann Arbor MI USA

Retinal laser photocoagulation is a proven, effective treatment for various retinal disorders, including diabetic retinopathy, retinal vein occlusions, and sickle cell retinopathy. To minimize iatrogenic retinal damage while maintaining therapeutic effects, retinal laser technology has evolved significantly since its introduction in ophthalmology more than half a century ago. These innovations have included both optimizations of laser parameters in addition to the development of novel laser delivery systems. This review summarizes recent innovations in retinal laser technology, including subthreshold micropulse laser, selective retinal therapy and nanosecond laser, innovative modes of laser delivery including pattern scanning laser, endpoint management, navigated laser, and newly described photo-mediated ultrasound therapy.

关键词： Retinal Laser Technology Pattern Scan Laser Navigated Laser Subthreshold Micropulse Laser Selective Retinal Therapy Photo-Mediated Ultrasound Therapy pascal

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