检索结果-南通市图书馆

Postoperative Analgesia and Cesarean Section under General Anesthesia: Multicenter Study

Open Journal of Anesthesiology 2024年第1期14卷 1-12页

作者： Ghislain Edjo Nkilly Raphael Okoue Ondo pascal christian nze obiang Stéphane Oliveira Jean-Marcel Mandji-Lawson Romain Tchoua Department of Anesthesia and Intensive Care Omar Bongo Ondimba Army Training Hospital (HIAOBO) Libreville Gabon Department of Anesthesia and Intensive Care Jeanne Ebori Fondation Libreville Gabon Department of Anesthesia and Intensive Care Akanda Army Training Hospital Libreville Gabon

Background: Neuraxial anesthesia with intrathecal morphine is the reference technique in cesarean section anesthesia for the management of postoperative analgesia. If there is a contraindication to this, general anesthesia is required. The objective of the study was to evaluate the analgesic effectiveness of 4 analgesic techniques performed during cesarean section under general anesthesia in two centers with different anesthetic practices (North Franche Comté Hospital and Omar Bongo Ondimba Army Training Hospital). Method: This is a retrospective and descriptive study over 2 years, from January 1, 2019 to December 31, 2020. It involved evaluating the analgesic effectiveness and tolerance of morphine in the epidural catheter, wound infiltration, intravenous analgesia and Transversus Abdominous Plane block (TAP block) from the post-anesthesia care unit (PACU) until the 4th post-operative day. Results: Of the 354 cesarean sections performed, 84 (11.14%) received general anesthesia. The average age was 32.27 years. Acute fetal distress was the first indication for cesarean section (45.2%), followed by hemorrhagic placenta previa (10.7%) and prolapse of the cord (8.33%). Morphine in the epidural catheter was the most used (47.6%) followed by parietal infiltration (36.9%), intravenous analgesia (13.1%) and TAP block (2.38%). The analgesic effectiveness was comparable between the techniques from postoperative day 0 to day 4. No difference in side effects. Postoperative morphine consumption was significantly reduced (p = 0.011) in the infiltration (9 mg) and TAP block (9mg) groups compared to the epidural catheter (16 mg) and intravenous analgesia (17 mg). No difference in 02 rehabilitation criteria (ambulation, first bowel movement). No difference in the occurrence of chronic pain. Conclusion: In the event of a cesarean section under general anesthesia, there are effective and well-tolerated alternatives to neuraxial anesthesia, particularly regional anesthesia

关键词： Cesarean General Anesthesia Morphine Parietal Infiltration Epidural Catheter Transversus Abdominis Plane Block Intravenous Analgesia

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Intermediate Hip Arthroplasty in Gabon: Blood Loss and Risk Factor for Transfusion

引用

Open Journal of Anesthesiology 2024年第4期14卷 109-117页

作者： Ghislain Edjo Nkilly pascal christian nze obiang Raphael Okoue Ondo Arthur Matsanga Stéphane Oliveira Léandre Nguiabanda Jean-Marcel Mandji-Lawson Department of Anaesthesia and Intensive Care Omar Bongo Ondimba Army Training Hospital (HIAOBO) Libreville Gabon Department of Anaesthesia and Intensive Care Jeanne Ebori Fondation Libreville Gabon Department of Anaesthesia and Intensive Care Owendo University Hospital (CHUO) Libreville Gabon Department of Anaesthesia and Intensive Care Akanda Army Training Hospital Libreville Gabon Orthopedic Surgery Service Omar Bongo Ondimba Army Training Hospital (HIAOBO) Libreville Gabon

Background: Hip arthroplasty is a surgery with a high risk of bleeding. The main objective of this study was to research risk factors for bleeding and transfusion in patients undergoing hip hemiarthroplasty in Gabon. Method: It was a retrospective, monocentric, descriptive and analytical study carried out from June 2011 to June 2021 at the Omar Bongo Ondimba army training hospital. The variables studied were demographic characteristics, biological variables, transfusion and intraoperative data. The primary outcome was intraoperative transfusion. A univariate and multivariate analysis was conducted to identify the factors associated with the occurrence of a transfusion. Results: Of the 97 patients included, the average age was 74.2 years ± 10, male predominance was 73.2%, the average ASA score was 1.9 ± 0.5, and transfusion incidence was 38.1%. The average number of RBCs transfused was 1.2 ± 0.6. Tranexamic acid was used in 11.3% of patients. The average bleeding was 450 ± 453 ml. Preoperative anemia was predictor of transfusion to be significant. Conclusion: The incidence of transfusion is law compared to total hip arthroplasty. The implementation of a patient blood management protocol is difficult given the urgency of bone repair. However, a better use of tranexamic acid could reduce this transfusion incidence.

关键词： Hip Arthroplasty Risk Factors Patients Hemiarthroplasty Gabon

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Postoperative Analgesia and Cesarean Section under General Anesthesia: Multicenter Study

引用

Open Journal of Anesthesiology（麻醉学期刊） 2024年第1期

作者： Ghislain Edjo Nkilly Raphael Okoue Ondo pascal christian nze obiang Stéphane Oliveira Jean-Marcel Mandji-Lawson Romain Tchoua

来源：博看期刊评论

在线全文

博看期刊

学校读者我要写书评

暂无评论

Intermediate Hip Arthroplasty in Gabon: Blood Loss and Risk Factor for Transfusion

引用

Open Journal of Anesthesiology（麻醉学期刊） 2024年第4期 109页

作者： Ghislain Edjo Nkilly pascal christian nze obiang Raphael Okoue Ondo Arthur Matsanga Stéphane Oliveira Léandre Nguiabanda Jean-Marcel Mandji-Lawson

来源：博看期刊评论

在线全文

博看期刊

学校读者我要写书评

暂无评论

Frequency of Transfusions and Risk Factor for Bleeding Risk to Guide a Blood-Sparing Program during Hip Arthroplasty in Gabon

引用

Open Journal of Anesthesiology 2023年第3期13卷 47-57页

作者： Ghislain Edjo Nkilly Raphael Okoue Ondo Arthur Matsanga pascal christian nze obiang Stéphane Oliveira Léandre Nguiabanda Jean-Marcel Mandji-Lawson Romain Tchoua Department of Anaesthesia and Intensive Care Omar Bongo Ondimba Army Training Hospital (HIAOBO) Libreville Gabon Department of Anaesthesia and Intensive Care Owendo University Hospital (CHUO) Libreville Gabon Department of Anaesthesia and Intensive Care Jeanne Ebori Fondation Libreville Gabon Department of Anaesthesia and Intensive Care Akanda Army Training Hospital Libreville Gabon Orthopedic surgery service Omar Bongo Ondimba Army Training Hospital (HIAOBO) Libreville Gabon

Background: Hip arthroplasty is a surgery with a high risk of bleeding. The main objective of this study was to research risk factors for bleeding and transfusion in patients undergoing hip arthroplasty in order to guide a blood-saving program. Method: Retrospective, monocentric, descriptive and analytical study carried out from June 2011 to June 2021 at the Omar Bongo Ondimba army training hospital. The variables studied were demographic characteristics, biological variables, transfusion data, anesthetic and intraoperative data. The primary outcome was intraoperative or postoperative transfusion. A univariate and multivariate analysis was conducted to identify the factors associated with the occurrence of a transfusion. Results: Of the 276 patients included, 179 benefited from Total Hip Prosthesis (THP) and 97 from Intermediate Hip Prosthesis (IHP). Spinal anesthesia was performed in 67.4% of patients. The ASA 2 score predominated (65.9%). The transfusion incidence was 56.9% (157/276). Tranexamic acid was used in 16.3% (45/276) of patients. The average bleeding was 528 ± 405 ml. Preoperative anemia (OR = 0.78, 95% CI [0.66 - 0.91]) and total hip prosthesis (OR = 2.02 95% CI [1.11 - 3.67]) were predictors of bleeding and transfusion to be significant. The average serum hemoglobin predictive of a transfusion was 11.6 ± 1.8. ASA score and operative time were not found as risk factors for bleeding and transfusion. Conclusion: The incidence of transfusion is high. Preoperative anemia remains a major but modifiable risk factor unlike the choice of implant. The implementation of a patient blood management protocol could reduce this transfusion incidence.

关键词： Arthroplasty Hip Gabon Transfusion

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frequency of Transfusions and Risk Factor for Bleeding Risk to Guide a Blood-Sparing Program during Hip Arthroplasty in Gabon

引用

Open Journal of Anesthesiology（麻醉学期刊） 2023年第3期

作者： Ghislain Edjo Nkilly Raphael Okoue Ondo Arthur Matsanga pascal christian nze obiang Stéphane Oliveira Léandre Nguiabanda Jean-Marcel Mandji-Lawson Romain Tchoua

来源：博看期刊评论

在线全文

博看期刊

学校读者我要写书评

暂无评论

Phytochemical Screening, Study of Acute Toxicity and Hypoglycemic and Antihyperglycemic Activities of Silver Nanoparticles from Guibourtia tessmannii (Harms) J. Leonard (Caesalpiniaceae)

引用

Open Journal of Applied Sciences 2024年第1期14卷 118-130页

作者： Ngoulé Charles christian Eya’ane Meva François Sone Enone Bertin Ngo Nyobe Biwole Caroline Tankeu Séverin Elisée Songue pascal Nguene Jean Pierre Etame-Loe Gisèle Department of Pharmaceutical Sciences Faculty of Medicine and Pharmaceutical Sciences University of Douala Douala Cameroon Department of Biology of Plant Organisms Faculty of Sciences University of Douala Douala Cameroon

According to the World Health Organization, diabetes affects approximately 347 million people worldwide. Its management is not within the reach of all social classes, therefore medicinal plants are still the first resort for many populations in Africa. The biological material used in this study was the trunk bark of Guibourtia tessmannii. 50 g of trunk bark powder were decocted in 500 ml of distilled water for 5 minutes were carried out. The method used for the synthesis of silver nanoparticles (AgNps) was an organometallic bio-reduction of silver nitrate salts mediated by various secondary metabolites contained in the plant extract. The study of the toxicity acute was conducted according to guideline 423 of the OECD protocol. The pharmacological activities were each carried out with 28 female rats divided into 7 groups of four rats. It was a question for the hypoglycemic activity of administering various doses of silver nanoparticles and other substances to the rats thirty minutes after the carbohydrate intake and for the anti-hyperglycemic activity of administering the same substances to the rats thirty minutes before the carbohydrate intake. The extraction yield was 8.76%. Only the alkaloid test was negative. After acute toxicity study, the LD50 was greater than 2000 mg/kg. Blood sugar tests revealed that glibenclamide 5 mg/kg, which is the reference molecule, lowered blood sugar more than the other treatments applied in the other batches. It was followed by treatment with silver nanoparticles at a dose of 400 μg/kg in both tests. It was therefore concluded that silver nanoparticles from G. tessmannii are good for the formulation of improved traditional medicines and bring up their afficacity .

关键词： Guibourtia tessmannii Nanoparticles Hypoglycemia Anti-Hyperglycemia

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Safety and in Vivo Anti-Inflammatory Activity of Ethanolic Extract of Ficus umbellata (Vahl.) Leaves

引用

Journal of Biosciences and Medicines 2024年第3期12卷 94-112页

作者： Atchadé pascal Tchogou Steven Amour Pyus Tanguy Vignon Chokki Gbèssohèlè Justin Behanzin Tétédé Rodrigue christian Konfo Perside Savoeda Félicienne Agbogba Léocardie Akpoli Lamine Baba-Moussa Maximin Senou Alphonse Sezan Experimental and Clinical Biology Unit (UBEC) Biotechnology Research Laboratory Medical and Pharmaceutical (LaRBiMeP) Na-tional School of Biosciences and Biotechnology of Dassa-Zoumé (ENSBBA) National University of Science Technology and Engi-neering of Abomey (UNSTIM) Dassa-Zoumé Benin Laboratory of Pharmacology and Improved Traditional Medicines (LPMTA) Faculty of Science and Technology (FAST) University of Abomey-Calavi (UAC) Abomey-Calavi Benin National University of Agriculture (UNA) Schools of Science and Techniques for Preservation and Processing of Agricultural Prod-ucts (ESTCTPA) Sakété Benin Laboratory of Biology and Molecular Typing in Microbiology Department of Biochemistry and Cell Biology Faculty of Science and Technology University of Abomey-Calavi Cotonou Benin

Toxicity is the totality of adverse effects, which can be functional and morphological lesions in a living organism, caused by a substance introduced in relatively high single doses or in small, repeated doses. The aim of this study was to assess the OECD-recommended acute oral toxicity and anti-inflammatory activity of ethanolic extract of Ficus umbellata leaves. Animals were given a single oral dose of 1000, 3000 and 5000 mg/Kg body weight (BW) of the extract. For the anti-inflammatory activity test, rats were given the ethanolic extract of F. umbellata leaves at doses of 100, 300 and 500 mg/Kg or aspirin® at a concentration of 100 mg/Kg PC orally, one hour before injection of 0.05 ml of 1% formalin under the plantar fascia of the rat’s right hind paw. Paw volume measurements were taken one, two and three hours after formalin injection, using an electronic caliper. After 14 days of observation, no deaths were observed in treated rats. The LD50 of ethanolic extract of Ficus umbellata leaf powder is greater than 5000 mg/Kg body weight. This extract has no significant effects on hematological parameters and on the main markers of nephrotoxicity and hepatotoxicity for a single dose of less than 5000 mg/Kg PC. It reduces formalin-induced edema. Evaluation of the percentage inhibition showed that the extract had greater anti-inflammatory activity at 3 hours after the start of the experiment. However, better inhibition of inflammatory oedema of the paw of rats treated with 500 mg/Kg was observed at 5 hours after the start of the experiment, with a percentage inhibition of 69.23 ± 1.02, compared with the reference group treated with aspirin® 100 mg/Kg, which showed an inhibition of 63.50 ± 0.98. These results show that F. umbellata leaves possess anti-inflammatory activity, which would justify their use in traditional African medicine to prevent or treat inflammation.

关键词： Ficus umbellata Toxicity Anti-Inflammatory Edema Inflammation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Segmental duodenectomy for gastrointestinal stromal tumor of the duodenum

引用

World Journal of Gastroenterology 2010年第22期16卷 2788-2792页

作者： Nicolas christian Buchs pascal Bucher pascal Gervaz Sandrine Ostermann Franois Pugin Philippe Morel Department of Surgery University Hospital Geneva

AIM: To evaluate the results of segmental duodenectomy (SD) and pancreaticoduodenectomy (PD) for duodenal gastrointestinal stromal tumor (GIST) and help clinicians with surgical management. METHODS: All patients who underwent surgery for non-metastatic GIST of the duodenum in a single institution since 2000 were prospectively followed up. Seven patients (median age 51 years, range: 41-73 years) were enrolled: five underwent SD and two underwent PD. RESULTS: All the patients had a complete resection (R0), with no postoperative morbidity and mortality. Among the SD group, GIST was classified as low risk in two patients, intermediate risk in two, and high risk in one, according to the Fletcher scale, (vs two high risk patients in the PD group). With a median followup of 41 (18-85) mo, disease-free survival (DFS) rateswere 100% after SD and 0% after PD (P < 0.05). The median DFS was 13 mo in the PD group. CONCLUSION: Whenever associated with clear surgical margins, SD is a reliable and curative option for most duodenal GISTs, and is compatible with longterm DFS.

关键词： Gastrointestinal stromal tumor Duodenal neoplasms Segmental duodenectomy Pancreaticoduodenectomy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Post-orogenic transients and relict landforms of the Bafoussam–Mamfe region(West-Cameroon Highland margin)

引用

Journal of Mountain Science 2022年第8期19卷 2180-2201页

作者： pascal Landry WABO DEFO Sébastien OWONA Moussa NSANGOU NGAPNA christian BALLA ATEBA christian MWABANUA MUTABI The University of Douala Faculty of ScienceDepartment of Earth SciencesDouala 24157Cameroon The University of Lubumbashi Faculty of ScienceDepartment of GeologyLubumbashi 1825Democratic Republic of Congo

The Bafoussam-Mamfe Region(BMR)belongs to the Western Cameroon Highland margin,an amalgam of transient landscape that evolved from the interactions between tectonics,lithology and climate *** area is tectonically active and shows differential tectonic uplift,contrasting relief,variations in erosion rates,in river incision,and in channel *** order to appraise the BMR tectono-geomorphic evolution,it is essential to understand relationships between internal and external processes and their geomorphic expression at a river basin *** this purpose,we use drainage texture(Dt),stream frequency(Fs),drainage density(Dd),asymmetry factor(AF),the transverse topographic symmetry factor(TTSF),the mean of mountain front sinuosity per unit(Smf),concavity factor(Cf),hypsometry integral(HI)and streamlength gradient index(SL-index)based on 30 m Digital Elevation Models(DEM)and field *** results reveal considerable variations in geology,relief,topography and geomorphic indices values differentiated into three geomorphic units;the Mamfe unit developed on the Mamfe Cretaceous basin,the Nguti and Bafoussam high plateau units build up on the Precambrian granito-gneissic basement overlaid by a volcanic *** stepped(longitudinal and normalized)river profiles and complex hypsometric curves show the lithostructural control of the hydrographic ***(from~1.21 to~4.59),Fs(from~0.26 to~1.91),Dd(from~0.66 to~1.71)geomorphic indice values indicate a part of lithologic control on this morphology while the AF(from~1.16to~24.91),TTSF(from~0.20 to~0.71),Smf(U2=1.11 and U3=1.19),Cf(from~-20.91 to~78.93),HI(from~0.12 to~0.52)and SL-index designate the active tectonics as the main factor that had controlled the morphology of this same *** results pinpoint the combined post-Pan-African to Recent tectonic features,lithologic heterogeneities and the differential erosion processes as main factors that have controlled the BMR *** results highlight how

关键词： Geomorphic indices Tectonic,Lithology Differential erosion Bafoussam-Mamfe Cameroon

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：