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Green Energy and Intelligent Transportation 2024年第2期3卷 60-78页

作者： Pritam Das partha Kayal Department of Electrical Engineering National Institute of Technology SilcharAssam788010India

Electric vehicles(EVs)are going to overrule the transportation sector due to their pollution-free technology and low running ***,charging the EVs causes significant power demand and stress on the power delivery *** challenge can be tackled well when charging and discharging scheduling are coordinated with intelligent EV *** this work,two-stage charging and discharging scheduling are *** the first stage,a time scheduling algorithm is structured to identify EV charging/discharging slots at different hours,and at a later stage,the slots are optimally distributed among different charging *** of the EVs towards the EVCSs has been designed to enhance the useful participation of the EVs in the charging and discharging *** this regard,a possible number of EVs in the test region has been forecasted with a regression *** adequacy of the combined charging-discharging and location scheduling model is tested on a typical PV-enhanced 28-bus Indian distribution *** case studies containing three sub-cases in each have been performed incorporating the choice of the EV owners towards charging and discharging in different time slots in a *** case studies have resulted in a peak-to-average ratio(PAR)of 1.151,0,1.165,0,1.196,8,1.165,0,1.180,9,1.196,8,1.196,8,1.196,8 and 1.196,8 for the 24-h demand pattern in Case-1a,Case-1b,Case-1c,Case-2a,Case-2b,Case-2c,Case-3a,Case-3b and Case-1c respectively in comparison to a PAR of 1.2 for the 24-h demand in base case.

关键词： Charging-discharging scheduling Electric vehicles Solar irradiance forecasting Optimization Distribution network

Target specificity of selective bioactive compounds in blocking α-dystroglycan receptor to suppress Lassa virus infection: an in silico approach

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The Journal of Biomedical Research 2021年第6期35卷 459-473页

作者： Adittya Arefin Tanzila Ismail Ema Tamnia Islam MdSaddam Hossen Tariqul Islam Salauddin Al Azad MdNasir Uddin Badal MdAminul Islam partha biswas Nafee Ul Alam Enayetul Islam Maliha Anjum Afsana Masud MdShaikh Kamran Ahsab Rahman Parag Kumar Paul Wolfson Institute for Biomedical Research Division of MedicineUniversity College LondonLondon WC1E6AEUK Department of Biochemistry and Microbiology North South UniversityDhaka 1229Bangladesh Faculty of Life Sciences and Medicine Zhejiang Sci-Tech UniversityHangzhouZhejiang 310018China Faculty of Pharmacy International Islamic University MalaysiaKuantanPahang 25200Malaysia School of Biotechnology Jiangnan UniversityWuxiJiangsu 214122China Department of Biomedical Technology Tampere UniversityTampere 33014Finland Department of Genetic Engineering and Biotechnology Jashore University of Science and TechnologyJashore 7408Bangladesh Department of Genetic Engineering and Biotechnology University of ChittagongChittagong 4331Bangladesh Applied Statistics and Data Science Jahangirnagar UniversityDhaka 1342Bangladesh Department of Mathematics and Natural Sciences Brac UniversityDhaka 1212Bangladesh Department of Electrical and Electronic Engineering United International UniversityDhaka 1212Bangladesh.

Lassa hemorrhagic fever,caused by Lassa mammarenavirus(LASV)infection,accumulates up to 5000 deaths every ***,there is no vaccine available to combat this *** this study,a library of 200 bioactive compounds was virtually screened to study their drug-likeness with the capacity to block theα-dystroglycan(α-DG)receptor and prevent LASV *** rigorous absorption,distribution,metabolism,and excretion(ADME)and quantitative structure-activity relationship(QSAR)profiling,molecular docking was conducted with the top ligands against theα-DG *** compounds chrysin,reticuline,and 3-caffeoylshikimic acid emerged as the top three ligands in terms of binding ***-docking analysis revealed that interactions with Arg76,Asn224,Ser259,and Lys302 amino acid residues of the receptor protein were important for the optimum binding affinity of *** dynamics simulation was performed comprehensively to study the stability of the protein-ligand ***-depth assessment of root-mean-square deviation(RMSD),root mean square fluctuation(RMSF),polar surface area(PSA),B-Factor,radius of gyration(Rg),solvent accessible surface area(SASA),and molecular surface area(MolSA)values of the protein-ligand complexes affirmed that the candidates with the best binding affinity formed the most stable protein-ligand *** authenticate the potentialities of the ligands as target-specific drugs,an in vivo study is underway in real time as the continuation of the research.

关键词： LASV infection α-dystroglycan receptor bioactive compounds target specificity molecular docking molecular dynamic simulations

ANTIVIRAL EFFECTS OF BACTERIOCIN AGAINST ANIMAL-TO-HUMAN TRANSMITTABLE MUTATED SARS-COV-2:A SYSTEMATIC REVIEW

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Frontiers of Agricultural Science and Engineering 2021年第4期8卷 603-622页

作者： Dipta DEY Tanzila Ismail EMA partha biswas Sharmin AKTAR Shoeba ISLAM Urmi Rahman RINIK Mahmudul FIROZ Shahlaa Zernaz AHMED Salauddin AL AZAD Ahsab RAHMAN Sadia AFRIN Rezwan Ahmed MAHEDI MdNasir Uddin BADAL Department of Biochemistry and Molecular Biology Bangabandhu Sheikh Mujibur Rahman Science&Technology UniversityGopalganj 8100Bangladesh Department of Microbiology and Biochemistry North South UniversityDhaka 1229Bangladesh Department of Genetic Engineering and Biotechnology Jashore University of Science and TechnologyJashore 7408Bangladesh Department of Microbiology University of DhakaDhaka 1000Bangladesh Department of Naval Architecture and Marine Engineering Bangladesh University of Engineering and TechnologyDhaka 1205Bangladesh Biotechnology and Genetic Engineering Discipline Khulna UniversityKhulna 9208Bangladesh Department of Mechanical and Production Engineering Islamic University of TechnologyGazipur 1704Bangladesh School of Biotechnology Jiangnan UniversityWuxi 214122China Department of Mathematics and Natural Sciences Brae UniversityDhaka 1212Bangladesh Department of Pharmacy Comilla UniversityComilla 3506Bangladesh Department of Biomedical Technology Tampere UniversityTampere 33100Finland

The COVID-19 caused by SARS-CoV-2 has resulted in millions of people being infected and thousands of deaths globally since November *** date,no unique therapeutic agent has been developed to slow the progression of this *** possessing antiviral traits the potential of bacteriocins to combat SARS-CoV-2 infection has not been fully *** review summarizes the mechanisms by which bacteriocins can be manipulated and implemented as effective virus entry blockers with infection suppression potential properties to highly transmissible viruses through comprehensive immune modulations that are potentially effective against *** antimicrobial peptides have been suggested as effective antiviral therapeutics and therapeutic supplements to prevent rapid virus *** review also provides a new insight into the cellular and molecular alterations which have made SARS-CoV-2 self-modified with diversified infection *** addition,the possible applications of antimicrobial peptides through both natural and induced mechanisms in infection prevention perspectives on changeable virulence cases are comprehensively *** attention is given to the antiviral mechanisms of the molecules along with their integrative use with synthetic biology and nanosensor technology for rapid *** bacteriocin based therapeutics with cutting-edge technologies might be potential substitutes for existing time-consuming and expensive approaches to fight this newly emerged global threat.

关键词： antimicrobial proteins antiviral profiling of bacteriocins antiviral therapeutics immunomodulation nanosensor technology mutated SARS-CoV-2

Clinical outcome of orbital apex syndrome in COVID associated mucormycosis patients in a tertiary care hospital

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International Journal of Ophthalmology(English edition) 2022年第4期15卷 527-532页

作者： Smiti Rani Srivastava Purban Ganguly Debasis Barman Sudip Das Manimoy Bandyopadhyay Asim Kumar Ghosh Subhra Sarkar Amitabha Sengupta Sarbari Swaika Pritam Chatterjee Amit Kumar Gupta Alok Ranjan Mondal Soumyajit Guha Sinjita Dutta Souvik Adhikari Aditi Kaushik partha Sundar biswas Asif Ayub Department of Ophthalmology Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial HospitalKolkata 999008India

AIM: To share clinical pattern of presentation, the modalities of surgical intervention and the one month postsurgical outcome of rhino-orbito-mucormycosis(ROCM) ***: All COVID associated mucormycosis(CAM) patients underwent comprehensive multidisciplinar y examination by ophthalmologist, otorhinolaryngologist and physician. Patients with clinical and radiological evidence of orbital apex involvement were included in the study. Appropriate medical and surgical intervention were done to each patient. Patients were followed up one-month post intervention. RESULTS: Out of 89 CAM patients, 31(34.8%) had orbital apex syndrome. Sixty-six(74.2%) of such patients had pre-existing diabetes mellitus, 18(58%) patients had prior documented use of steroid use, and 55(61.8%) had no light perception(LP) presenting vision. Blepharoptosis, proptosis, complete ophthalmoplegia were common clinical findings. Seventeen(19.1%) of such patients had variable amount of cavernous sinus involvement. Endoscopic debridement of paranasal sinuses and orbit with or without eyelid sparing limited orbital exenteration was done in most cases, 34(38.2%) patients could retain vision in the affected eye. CONCLUSION: Orbital apex involvement in CAM patients occur very fast. It not only leads to loss of vision but also sacrifice of the eyeball, orbital contents and eyelids. Early diagnosis and prompt intervention can preserve life, vision and spare mutilating surgeries.

关键词： rhino-orbito-cerebral mucormycosis COVID associated mucormycosis orbital exenteration endoscopic paranasal sinus debridement orbital apex syndrome

Development of a simple RPM measurement system

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Journal of Measurement Science and Instrumentation 2020年第2期11卷 193-196页

作者： Akash Kumar Anindya Debnath Antar Banik Kabirul Islam Mondal partha Pratim biswas Rik Bhattacharyya T K Maiti Department of Applied Electronics&Instrumentation Engineering Netaji Subhash Engineering CollegeKolkata 700152West Bengal Department of Instrumentation Engineering Central Institute of Technology KokrajharAssam 783370India

The design and development of a timer based revolution per minute(RPM)measurement system were described in this *** rotating shaft of a dc motor was used to measure the RPM and timer integrated circuit(IC)555 was used in astable *** frequency of timer output waveform measured by a digital storage oscilloscope(DSO)is almost linearly proportional to the RPM of rotating shaft,and the RPM also linearly varies with the change of the external input voltage *** the linear relationship between the frequency of timer output waveform and the RPM can be *** main advantages of this developed system are linear input-output relationship,small size,easy to carry and cost effective.

关键词： IC 555 astable multivibrator RPM measurement

Development of OPTO-LDR coupled timer based voltage to frequency converter

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Journal of Measurement Science and Instrumentation 2017年第1期8卷 17-20页

作者： Akash Kumar Anindya Debnath Antar Banik Kabirul Islam Mondal partha Pratim biswas Rik Bhattacharyya T K Maiti 德里理工学院应用电子与仪器工程系印度加尔各答700152

This paper describes the development of a timer based voltage to frequency converter(V FC).Timer LM555is used in astable multivibrator mode with two OPTO-LDRs(light dependent resistors)in the *** frequency of timer output waveform which is measured using a digital storage oscillator(DSO)is almost linearly proportional to the applied input *** we obtain a linear relationship between the frequency of timer output waveform and the input *** of its quasi-digital output,the main advantages of this developed converter are linear input-output relationship,small size,easy portabilityand high cost *** addition,the timer output waveform can be directly interfaced with personal computer or microprocessor/microcontroller for further processing of the input voltage signal without intervening any analog-to-digital converter(ADC).

关键词： timer LM 555 astable multivibrator light emitting diode (LED) light dependent resistor (LDR) voltage to frequency converter (V FC) digital storage oscillator (DSO)

ChatGPT in transforming communication in seismic engineering: Case studies, implications, key challenges and future directions

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Earthquake Science 2024年第4期37卷 352-367页

作者： partha Pratim Ray Department of Computer Applications Sikkim UniversityGangtokIndia

Seismic engineering,a critical field with significant societal implications,often presents communication challenges due to the complexity of its *** paper explores the role of Artificial Intelligence(AI),specifically OpenAI’s ChatGPT,in bridging these communication *** study delves into how AI can simplify intricate seismic engineering terminologies and concepts,fostering enhanced understanding among students,professionals,and *** also presents several intuitive case studies to demonstrate the practical application of ChatGPT in seismic ***,the study contemplates the potential implications of AI,highlighting its potential to transform decision-making processes,augment education,and increase public *** acknowledging the promising future of AI in seismic engineering,the study also considers the inherent challenges and limitations,including data privacy and potential oversimplification of *** advocates for the collaborative efforts of AI researchers and seismic experts in overcoming these obstacles and enhancing the utility of AI in the *** exploration provides an insightful perspective on the future of seismic engineering,which could be closely intertwined with the evolution of AI.

关键词： AI ChatGPT seismic engineering decision making earthquake science

Role of T cells in cancer immunotherapy:Opportunities and challenges

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Cancer Pathogenesis and Therapy 2023年第2期1卷 116-126页

作者： Hossain Ahmed Aar Rafi Mahmud Mohd.Faijanur-Rob-Siddiquee Asif Shahriar partha biswas Ebrahim Khalil Shimul Shahlaa Zernaz Ahmed Tanzila Ismail Ema Nova Rahman Arif Khan Furkanur Rahaman Mizan Talha Bin Emran Department of Biotechnology and Genetic Engineering University of Development Alternative(UODA)4/4BBlock ALalmatiaDhaka1209Bangladesh Department of Biochemistry and Molecular Biology Mawlana Bhashani Science and Technology UniversityTangail1902Bangladesh Department of Biochemistry and Molecular Biology Faculty of Biological ScienceUniversity of DhakaDhaka1000Bangladesh Department of Immunology and Microbiology School of MedicineUniversity of Texas Rio Grande ValleyMcAllenTX78504USA Department of Genetic Engineering and Biotechnology Faculty of Biological Science and TechnologyJashore University of Science and Technology(JUST)Jashore7408Bangladesh Department of Biochemistry and Microbiology North South UniversityDhaka1229Bangladesh Department of Biochemistry and Molecular Biology Jahangirnagar UniversitySavarDhaka1342Bangladesh Department of Food Science and Technology Chung-Ang UniversityAnseong17546Republic of Korea Department of Pharmacy BGC Trust University BangladeshChittagong4381Bangladesh Department of Pharmacy Faculty of Allied Health SciencesDaffodil International UniversityDhaka1207Bangladesh

Immunotherapies boosting the immune system's ability to target cancer cells are promising for the treatment of various tumor types,yet clinical responses differ among patients and ***,there has been increasing interest in novel cancer immunotherapy practices aimed at triggering T cell-mediated anti-tumor ***-directed cytotoxicity mediated by T lymphocytes has become a central focal point in the battle against cancer utilizing the immune *** molecular and cellular mechanisms involved in the actions of T lymphocytes have directed new therapeutic approaches in cancer immunotherapy,including checkpoint blockade,adoptive and chimeric antigen receptor(CAR)T cell therapy,and cancer *** review addresses all the strategies targeting tumor pathogenesis,including metabolic pathways,to evaluate the clinical significance of current and future immunotherapies for patients with cancer,which are further engaged in T cell activation,differentiation,and response against tumors.

关键词： Immunotherapy T cell Cancer Immune system Metabolic pathways

Artificial intelligence strengthenes cervical cancer screening–present and future

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Cancer Biology & Medicine 2024年第10期 864-879页

作者： Tong Wu Eric Lucas Fanghui Zhao partha Basu Youlin Qiao School of Population Medicine and Public Health Chinese Academy of Medical Sciences and Peking Union Medical College Early Detection Prevention & Infections Branch International Agency for Research on Cancer (WHO) Department of Cancer Epidemiology National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College

Cervical cancer is a severe threat to women's health. The majority of cervical cancer cases occur in developing countries. The WHO has proposed screening 70% of women with high-performance tests between 35 and 45 years of age by 2030 to accelerate the elimination of cervical cancer. Due to an inadequate health infrastructure and organized screening strategy, most low-and middleincome countries are still far from achieving this goal. As part of the efforts to increase performance of cervical cancer screening, it is necessary to investigate the most accurate, efficient, and effective methods and strategies. Artificial intelligence(AI) is rapidly expanding its application in cancer screening and diagnosis and deep learning algorithms have offered human-like interpretation capabilities on various medical images. AI will soon have a more significant role in improving the implementation of cervical cancer screening, management, and follow-up. This review aims to report the state of AI with respect to cervical cancer screening. We discuss the primary AI applications and development of AI technology for image recognition applied to detection of abnormal cytology and cervical neoplastic diseases, as well as the challenges that we anticipate in the future.

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Non-alcoholic fatty liver disease in type 2 diabetes:Emerging evidence of benefit of peroxisome proliferator-activated receptors agonists and incretin-based therapies

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World Journal of Methodology 2024年第2期14卷 38-50页

作者： Subhodip Pramanik partha Pal Sayantan Ray Department of Endocrinology Neotia Getwel Multispecialty HospitalSiliguri 734010West BengalIndia Department of Medical Gastroenterology Asian Institute of GastroenterologyHyderabad 500082India Department of Endocrinology All India Institute of Medical SciencesBhubaneswarBhubaneswar 751019OdishaIndia

Nonalcoholic fatty liver disease(NAFLD)is a global epidemic,affecting more than half of the people living with type 2 diabetes(T2D).The relationship between NAFLD and T2D is bidirectional and the presence of one perpetuates the other,which significantly increases the hepatic as well as extrahepatic *** recently,there was no approved pharmacological treatment for NAFLD/nonalcoholic steatohepatitits(NASH).However,there is evidence that drugs used for diabetes may have beneficial effects on *** sensitizers acting through peroxisome proliferator-activated receptor(PPAR)modulation act on multiple levels of NAFLD ***(PPARγ agonist)and saroglitazar(PPARα/γagonist)are particularly beneficial and recommended by several authoritative bodies for treating NAFLD in T2D,although data on biopsyproven NASH are lacking with the *** data on elafibanor(PPARα/δ agonist)and Lanifibranor(pan PPAR agonist)are *** the other hand,incretin therapies based on glucagon-like peptide-1(GLP-1)receptor agonists(GLP-1RA)and dual-and triple-hormone receptor co-agonists reported impressive weight loss and may have anti-inflammatory and antifibrotic ***-1 RAs have shown beneficial effects on NAFLD/NASH and more studies on potential direct effects on liver function by dual-and triple-agonists are ***,the long-term safety of these therapies in NAFLD needs to be *** efforts among healthcare providers such as primary care doctors,hepatologists,and endocrinologists are warranted for selecting patients for the best possible management of NAFLD in T2D.

关键词： Non-alcoholic fatty liver disease Type 2 diabetes Evidence PPAR agonists Incretin-based therapies