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FRACTAL pORE dIFFUSION MOdEL OF FLUIdS IN pOROUS MEdIA

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Acta Metallurgica Sinica(English Letters) 2000年第3期13卷 877-882页

作者： Tao, d.p. Kunming Univ of Science and Technology Kunming China

A fractal pore diffusion model of fluids in porous media which is in good agreement with the experimental data of the coke-CO2 reaction, has been derived by using the Mandelbrot's fractal length-area relation. Based on the model, a new formula and its interpretation about the tortuosity of pore structures of a porous medium have been suggested, from which the fractal pore diffusion resistance has been defined. The resistance ascends obviously with the fractal pore dimension and the conversion ratio increasing, especially in the middle-latter period of fluid-solid reactions.

关键词： Carbon dioxide Chemical reactions Coke Fractals Geometry Models porous materials

Treating amyotrophic lateral sclerosis with allogeneic Schwann cell-derived exosomal vesicles: a case report

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Neural Regeneration Research 2025年第4期20卷 1207-1216页

作者： pascal J.Goldschmidt-Clermont Aisha Khan George Jimsheleishvili patricia Graham Adriana Brooks Risset Silvera Alexander J.p.Goldschmidt damien d.p.arse W.dalton dietrich Allan d.Levi James d.Guest Miller School of Medicine University of MiamiMiamiFLUSA Stem Cell Institute Miller School of MedicineUniversity of MiamiMiamiFLUSA The Miami project to Cure paralysis Miller School of MedicineUniversity of MiamiMiamiFLUSA Alzady International LLC MiamiFLUSA Neurological Surgery Miller School of MedicineUniversity of MiamiMiamiFLUSA

Schwann cells are essential for the maintenance and function of motor neurons,axonal networks,and the neuromuscular *** amyotrophic lateral sclerosis,where motor neuron function is progressively lost,Schwann cell function may also be ***,important signaling and.p.tential trophic activities of Schwann cell-derived exosomal vesicles have been *** case report describes the treatment of a patient with advanced amyotrophic lateral sclerosis using serial intravenous infusions of allogeneic Schwann cell-derived exosomal vesicles,marking,to our knowledge,the first instance of such *** 81-year-old male patient presented with a 1.5-year history of rapidly progressive amyotrophic lateral *** initial diagnosis,the patient underwent a combination of generic riluzole,sodium phenylbutyrate for the treatment of amyotrophic lateral sclerosis,and *** patient volunteered to participate in an FdA-approved single-patient expanded access treatment and received weekly intravenous infusions of allogeneic Schwann cell-derived exosomal vesicles to potentially restore impaired Schwann cell and motor neuron *** confirmed that cultured Schwann cells obtained from the amyotrophic lateral sclerosis patient via sural nerve biopsy appeared impaired(senescent)and that exposure of the patient’s Schwann cells to allogeneic Schwann cell-derived exosomal vesicles,cultured expanded from a cadaver donor improved their growth capacity in *** a period of observation lasting 10 weeks,during which amyotrophic lateral sclerosis Functional Rating Scale-Revised and.p.lmonary function were regularly monitored,the patient received weekly consecutive infusions of 1.54×1012(×2),and then consecutive infusions of 7.5×1012(×6)allogeneic Schwann cell-derived exosomal vesicles diluted in 40 mL of dulbecco’s phosphate-buffered *** of the infusions were associated with adverse events such as infusion reactions(allergic or otherwise)or

关键词： allogeneic amyotrophic lateral sclerosis exosomes infusion neuromuscular junction Schwann cell

Artificial Neural Network （ANN） and Regression Tree （CART） applications for the indirect estimation of unsaturated soil shear strength parameters

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Frontiers of Earth Science 2014年第3期8卷 439-456页

作者： d.p. KANUNGO Shaifaly SHARMA Anindya pAIN Geotechnical Engineering Group CSIR - Central Building Research Institute (CBRI) Roorkee 247667 India

The shear strength parameters of soil （cohesion and angle of internal friction） are quite essential in solving many civil engineering problems. In order to determine these parameters, laboratory tests are used. The main objective of this work is to evaluate the potential of Artificial Neural Network （ANN） and Regression Tree （CART） techniques for the indirect estimation of these parameters. Four different models, considering different combinations of 6 inputs, such as gravel %, sand %, silt %, clay %, dry density, and.p.asticity index, were investigated to evaluate the degree of their effects on the prediction of shear parameters. A performance evaluation was carried out using Correlation Coefficient and Root Mean Squared Error measures. It was observed that for the prediction of friction angle, the performance of both the techniques is about the same. However, for the prediction of cohesion, the ANN technique performs better than the CART technique. It was further observed that the model considering all of the 6 input soil parameters is the most appropriate model for the prediction of shear parameters. Also, connection weight and bias analyses of the best neural network （i.e., 6/2/2） were attempted using Connec- tion Weight, Garson, and.p.oposed Weight-bias approaches to characterize the influence of input variables on shear strength parameters. It was observed that the Connection Weight Approach provides the best overall methodology for accurately quantifying variable importance, and should be favored over the other approaches examined in this study.

关键词： cohesion friction angle Artificial NeuralNetwork Regression Tree Connection Weight Weight-bias Approach

Recoil polarimetry with the Crystal Ball at MAMI

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Chinese physics C 2009年第12期33卷 1183-1188页

作者： d.p. Watts d.I. Glazier M.S. Sikora University of Edinburgh King's Buildings Edinburgh EH9 3JZ UK

The spectrum and.p.operties of the excited states of the nucleon are still poorly established despite decades of study. These proceedings describe new measurements of pseudo-scalar meson photoproduction at the Crystal Ball at MAMI, employing a new large acceptance nucleon recoil polarimeter. The double- and single-polarisation observables obtained will provide valuable and unique data to be used as part of the world effort to improve our knowledge of this fundamental spectrum.

关键词： photoproduction reactrons

Recoil polarimetry in meson photoproduction at MAMI

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Chinese physics C 2009年第12期33卷 1373-1376页

作者： M.H. Sikora d.I. Glazier d.p. Watts University of Edinburgh King’s Buildings Edinburgh EH9 3JZ United Kingdom

The nucleon excitation spectrum remains poorly known, with the masses, widths, EM couplings and even existence of many states not well established. A program of experiments using meson photoproduction off the nucleon is being carried out to improve this situation. A new large acceptance recoil polarimeter has been developed by the Edinburgh group for use in such reactions with the Crystal Ball at MAMI. This work summarizes the procedure used to measure recoil polarization with the new device and.p.esents some preliminary results for the double polarization observable Cx in the reaction γp→pπ, compared to the current partial wave analysis.

关键词： polarimeter meson photoproduction polarization observable recoil

Anti-amyloid antibodies in Alzheimer’s disease: what did clinical trials teach us?

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Neural Regeneration Research 2025年第4期20卷 1092-1093页

作者： danko Jeremic Lydia Jiménez-díaz Juan d.Navarro-López Neurophysiology&Behavior Lab University of Castilla-La ManchaBiomedical Research Center(CRIB)School of Medicine of Ciudad RealCiudad RealSpain

Although many causes of Alzheimer’s disease(Ad)may exist,both the original amyloid cascade and tau hypotheses posit that abnormal misfolding and accumulation of amyloid-β(Aβ)and tau protein is the central event causing the ***,that conclusion could be only partly true,and there is conflicting evidence about the role of both proteins in Ad,being able to precede and influence one *** researchers argue that these proteins are mere executors rather than primary causes of ***,there have been continuing refinements of both hypotheses,with alternative explanations proposed.Aβand tau proteins may be ind.p.ndently involved in specific neurotoxic pathways;yet there may be other crucial processes going on in early ***,accumulating evidence suggests that Aβand tau act synergistically,rather than additively in disease onset(Jeremic et al.,2021,2023a).

关键词： amyloid Alzheimer additive

Remaking a connection:molecular players involved in post-injury synapse formation

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Neural Regeneration Research 2025年第6期20卷 1719-1720页

作者： diogo Tomé Ramiro d.Almeida iBiMEd-Institute of Biomedicine Department of Medical SciencesUniversity of AveiroAveiroPortugal CNC-Center for Neuroscience and Cell Biology University of CoimbraCoimbraPortugal

Functional recovery from central nervous system(CNS)trauma d.p.nds not only on axon regeneration or compensatory sprouting of uninjured fibers but also on the ability of newly grown axons to establish functional synapses with appropriate *** several studies have successfully promoted long-distance axonal regeneration in distinct CNS injury models,none of them have resulted in a viable therapeutic approach for patient recovery.A possible reason may be the lack of new synaptogenesis for reestablishing the circuitry lost after ***,we discuss how our understanding of the mechanisms that instruct synapse formation in the injured nervous system may contribute to the design of new strategies to promote functional restoration in traumatic CNS disorders.

关键词： viable injury instru

A SIMpLE pRECONdITIONEd dOMAIN dECOMpOSITION METHOd FOR ELECTROMAGNETIC SCATTERING pROBLEMS

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Journal of Computational Mathematics 2013年第1期31卷 1-21页

作者： F. Alouges J. Bo-urguignon-Mirebeau - I d.p. Levadoux CMAp Ecole Polytechnique Palaiseau France Laboratoire de Mathdmatiques Universitd Paris-Sud XI Orsay France dEMR-SFM ONERA Palaiseau France

We present a domain decomposition method （ddM） devoted to the iterative solution of time-harmonic electromagnetic scattering problems, involving large and resonant cavities. This ddM uses the electric field integral equation （EFIE） for the solution of Maxwell problems in both interior and exterior subdomains, and we propose a simple preconditioner for the global method, based on the single layer operator restricted to the fictitious interface between the two subdomains.

关键词： Electromagnetism integral equations methods domain decomposition meth-ods preconditioning Cavities.

pREdICTION OF THE MIXING ENTHALpIES OF BINARY LIQUId ALLOYS BY MOLECULAR INTERACTION VOLUME MOdEL

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Acta Metallurgica Sinica(English Letters) 2008年第5期21卷 336-340页

作者： H.W. Yang d.p. Tao Z.H. Zhou Faculty of Materials and Metallurgical Engineering Kunming University of Science and Technology Kunming 650093 China

The mixing enthalpies of 23 binary liquid alloys are calculated by molecular interaction volume model （MIVM）, which is a two-parameter model with the partial molar infinite dilute mixing enthalpies. The predicted va... 详细信息

关键词： Molecular interaction volume model Mixing enthalpy Liquid alloys prediction