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Chemical identification,antioxidant,cholinesterase inhibitory,and cytotoxic properties of fucoidan extracted from Persian Gulf Sargassumangustifolium

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Acta Oceanologica Sinica 2022年第12期41卷 133-141页

作者： Arghavan Hosseinpouri Mehdi Mohammadi Elham Ehsandoost paria sharafi-badr Narges Obeidi Department of Cellular and Molecular Sciences Faculty of SciencesPersian Gulf UniversityBushehr 75168Iran Department of Marine Biotechnology Persian Gulf InstitutePersian Gulf UniversityBushehr 75168Iran Department of Biotechnology Persian Gulf Algae Development TechnologyDelvar Industrial Zone No.55Bushehr 75168Iran Department of Food Science and Technology Shiraz UniversityShiraz 71441-65186Iran Department of Pharmacognosy and Pharmaceutical Biotechnology School of PharmacyIran University of Medical SciencesTehran 14496-14535Iran Department of Hematology Faculty of ParamedicineBushehr University of Medical SciencesBushehr 75146-33341Iran

Marine macroalgal sulfated fucose-containing polysaccharides,like fucoidan,have drawn significant attention due to their biotechnological potentials,such as anti-cancer,antioxidant,and anti-cholinesterase *** fucoidan derived from brown macroalgae Sargassum angustifolium species(FSA)was investigated for its cytotoxic effects and alterations in cell proliferation,and cell cycle-related gene expression in the present study occurred on NB4 cell *** results showed that FSA would induce p53,p21,pro-apoptotic genes and increase expression of the p15 gene as a cell arrest ***,FSA inhibited the anti-apoptotic effect of the Bcl-2 gene and decreased dnmt-1 gene *** significantly exhibited potent 2,2-diphenyl-1-picrylhydrazyl(DPPH)radical scavenging activity(p<0.05)with an IC_(50) value of 0.157 mg/mL and showed moderate anti-acetylcholinesterase activity with an IC_(50) value of 1.20μg/*** results indicated the potential of FSA for the development of therapeutic or preventive agents of cancer and Alzheimer’s disease mainly through cytotoxic effect and AChE(acetylcholinesterase)inhibition as well as additional antioxidant capacities.

关键词： fucoidan Sargassum angustifolium cytotoxicity antioxidant anti-cholinesterase

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Review and evaluation of methods in transport mode detection based on GPS tracking data

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Journal of Traffic and Transportation Engineering(English Edition) 2021年第4期8卷 467-482页

作者： paria Sadeghian Johan Håkansson Xiaoyun Zhao School of Technology and Business Studies Dalarna UniversityFalunSweden Integrated Transport Research Lab KTH Royal Institute of TechnologyStockholmSweden

Mobility data,based on global positioning system(GPS)tracking,have been widely used in many areas,such as analyzing travel patterns,investigating transport safety and efficiency,and evaluating travel *** modes are essential factors in understanding mobility within the transport ***,in this study,a significant number of algorithms were tested for transport mode ***,no conclusive recommendations can be drawn regarding which method should be *** evaluation of the performance of the algorithms was not discussed systematically either in current *** paper aims to provide an in-depth review of the methods applied in transport mode detection based on GPS tracking *** performances of the reviewed methods are then compared and evaluated to provide guidance in choosing algorithms for transport mode detection based on GPS tracking *** results indicate that the majority of current studies are based on a supervised learning method for transport mode *** of the reviewed methods first require manual dataset labeling,which can produce major drawbacks,such as inefficiency and human *** was also found that deep learning approaches have the potential to deal with large amounts of unlabeled raw GPS datasets and increase the accuracy and efficiency of transport mode detection.

关键词： Traffic engineering Transport mode detection Machine learning Statistical learning Rule-based method Deep learning

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Structure Organization of Urinary System in the Yellow Spotted Mountain Newts (Salamandridae: Neurergus microspilotus)

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Asian Herpetological Research 2014年第1期5卷 60-65页

作者： paria PARTO Somaye VAISSI Mozafar SHARIFI Department of Biology Razi University Department of Biology Razi University Center for Environmental Studies

This study deals with the histomorphology of the mesonephros in male and female Neurergus microspilotus. The slender and narrow kidneys are positioned in the retro peritoneal position up against the ventral aspect of vertebral column and may extend the length from the esophagus-stomach junction to cloaca. The kidney in both sexes is composed of sexual（anterior） and pelvic（posterior） parts. The duct of sexual kidney is a narrow duct which is lying alongside its lateral edge. In the female, it is connected to the ureters and then the duct of defi nitive kidney. Before entering the cloaca, two ureters are joined together and open to the apex of the cloaca. In the male, after entering the sexual kidney, the sperm leave the testis through efferent ducts, then these ducts join together and eventually form Bidder＇s duct. The Bidder＇s duct joins the Bowman＇s capsule of the nephrons in the sexual kidney and the nephrons make collecting ducts which are fi lled with both sperm and urine. After leaving the kidney, all the collecting ducts are connected to the Wolffi an duct. Wolffi an duct joins the ureters（merge from defi nitive kidney） just before entering the cloaca. Based on serial paraffi n sections, nephrons consist of a fi ltration unit, the Malpighian corpuscle, and a renal tubule, which can be divided into 4 morphologically distinct segments： proximal tubule（first and second segment）, distal tubule, and collecting tubule. Collecting tubules merge and form a branch system that opens into collecting ducts.

关键词： Neurergus microspilotus sexual kidney pelvic kidney ureters

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Deep learning in fault detection and diagnosis of building HVAC systems: A systematic review with meta analysis

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能源与人工智能(英文) 2023年第2期12卷 206-233页

作者： Fan Zhang Nausheen Saeed paria Sadeghian School of Technology and Business Studies Sweden Department of Energy Technology Dalarna UniversityFalun79188Sweden

Building sector account for significant global energy consumption and Heating Ventilation and Air Conditioning (HVAC) systems contribute to the highest portion of building energy consumption. Therefore, the potential for energy saving by improving the efficiency of HVAC systems is huge and various fault detection and diagnosis (FDD) methods have been studied for this purpose. Although amongst all types of existing FDD methods, datadriven based ones are regarded as the most effective methods. As a relatively new branch of data-driven approaches, deep learning (DL) methods have shown promising results, a comprehensive review of DL applications in this area is absent. To fill the research gap, this systematic review with meta analysis analyses the relevant studies both quantitatively and qualitatively. The review is conducted by searching Web of Science, ScienceDirect, and Semantic search. There are 47 eligible studies included in this review following the preferred reporting items for systematic reviews and meta-analyses (PRISMA) protocol. 6 out of the 47 studies are identified as eligible for meta analysis of the effectiveness of DL methods for FDD. The most used DL method is 2D convolutional neural network (CNN). Results suggest that DL methods show promising results as a HVAC FDD. However, most studies use simulation/lab experiment data and real-world complexities are not fully investigated. Therefore, DL methods need to be further tested with real-world scenarios to support decision-making.

关键词： HVAC Deep learning Systematic review Meta analysis Fault detection and diagnosis

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City Digital Twins: their maturity level and differentiation from 3D city models

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Big Earth Data 2023年第1期7卷 1-36页

作者： Homa Masoumi Sara Shirowzhan paria Eskandarpour Christopher James Pettit Department of Urban and Regional Planning Shahid Beheshti UniversityTehranIran School of Built Environment UNSW SydneySydneyAustralia Faculty of Information Technology Monash UniversityClaytonVICAustralia Faculty of Arts Design and ArchitectureCity Futures Research CentreUNSW SydneyNSWAustralia

The emerging field of City Digital Twins has advanced in recent years with the help of digital infrastructure and technologies connected to the Internet of Things(IoT).However,the evolution of this field has been so fast that a gap has opened in relation to systematic reviews of the relevant literature and the maturation of City Digital Twins on an urban *** work bridges this gap by highlighting maturity in the *** conducted a systematic literature review with bibliometric and content analysis of 41 selected papers published in Web of Science and Scopus data-bases,covering five areas:data types and sources,case studies,applied technologies and methods,maturity spectrum,and *** on maturity indicators,the majority of the reviewed studies(90%)were at initial to medium stages of maturity(up to element 3),most of them focused on 3D modelling,monitoring and ***,digital twins cannot be limited to 3D models,monitoring and visualisation,for they can be developed to include two-directional interactions between humans and *** a high level of maturity,which was not found in the reviewed studies,requires advanced technologies and methods such as cloud computing,artificial intelligence,BIM and *** also found that further studies are essential if the field is to handle the complex urban challenges of multidisciplinary digital *** City Digital Twins extend by definition beyond mere 3D city modelling,some studies involving 3D city models still refer to their subjects as City Digital *** the research gaps we identified,we’d like to highlight the need for near-real-time data analytics algorithms,which could furnish City Digital Twins with big data *** opportunities include public participation capabilities to increase social collaboration,integrating BIM and GIS technologies and improving storage and computation infrastructure.

关键词： City Digital Twins big data IoT artificial intelligence city information modelling

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Microbiological and Histological Examinations of Endangered Neurergus kaiseri Tissues Displaying Red-leg Syndrome

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Asian Herpetological Research 2014年第3期5卷 204-208页

作者： paria PARTO Zahra M.S.HAGHIGHI Somaye VAISSI Mozafar SHARIFI Department of Biology Faculty of Science Razi University Faculty of Veterinary Science Department of basic Science Razi University

Presence of the red leg syndrome （RLS） was documented through bacterial and histological examinations in the endangered Kaiser＇s mountain newt Neurergus kaiseri obtained from a pet shop. The individuals which were severely infected showed lethargy, appetite loss, weight loss, abdominal skin redness and skin ulcers on hind legs. This study reveals the presence of two bacteria causing RLS on the skin of captive AT. kaiseri including Proteus vulgaris and Bacillus cereus. Sections of skin in affected areas and internal organs were examined through standard histological procedures. Histologically, epidermal necrosis and ulcers, epidermal gland depletion, myositis and subcutaneous edema, gastric submucosal edema and hepatomegaly were seen. There were also correlations between the microbial infection and structural changes in tissues of Kaiser＇s mountain newt. The severity of the structural changes are related to the level of microbial infection in the target organs and could be sustained by the isolation of P. vulgaris and other pathogens. The presence of the infective bacterial population and their interaction on the skin of the newt may have changed the normal skin flora and facilitate the prevalence of other disease.

关键词： Neurergus kaiseri red-leg syndrome lethargy abdominal skin redness skin ulcers

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Organoids: a novel modality in disease modeling

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Bio-Design and Manufacturing 2021年第4期4卷 689-716页

作者： Zahra Heydari Farideh Moeinvaziri Tarun Agarwal paria Pooyan Anastasia Shpichka Tapas KMaiti Peter Timashev Hossein Baharvand Massoud Vosough Department of Stem Cells and Developmental Biology Cell Science Research CenterRoyan Institute for Stem Cell Biology and TechnologyACECRTehran 14155-4364Iran Department of Developmental Biology University of Science and CultureTehran 14155-4364Iran Department of Biotechnology Indian Institute of TechnologyKharagpurWest Bengal 721302India World-Class Research Center“Digital Biodesign and Personalized Healthcare” Sechenov First Moscow State Medical University19991 MoscowRussia Institute for Regenerative Medicine Sechenov University119991 MoscowRussia Chemistry Department Lomonosov Moscow State University119991 MoscowRussia Department of Polymers and Composites N.N.Semenov Federal Research Center for Chemical PhysicsRussian Academy of Sciences119991 MoscowRussia Department of Regenerative Medicine Cell Science Research CentreRoyan Institute for Stem Cell Biology and TechnologyACECRTehran 14155-4364Iran

Limitations of monolayer culture conditions have motivated scientists to explore new models that can recapitulate the architecture and function of human organs more *** advances in the improvement of protocols have resulted in establishing three-dimensional(3D)organ-like architectures called‘organoids’that can display the characteristics of their corresponding real organs,including morphological features,functional activities,and personalized responses to specific *** discuss different organoid-based 3D models herein,which are classified based on their original germinal *** of organoids simulating the complexity of real tissues could provide novel platforms and opportunities for generating practical knowledge along with preclinical studies,including drug screening,toxicology,and molecular pathophysiology of *** paper also outlines the key challenges,advantages,and prospects of current organoid systems.

关键词： Organoid Germ layer Disease modeling Drug screening

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Consideration of Blood Serum Biochemical Parameters of Yellow Fin Sea Bream (<i>Acantopagrus latus</i>Houttuyn, 1782) and Orange-Spotted Grouper (<i>Epinephelus coioides</i>Hamilton, 1822)

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Advances in Biological Chemistry 2014年第6期4卷 407-413页

作者： paria Akbary Fisheries Group Department of Marine Sciences Chabahar Maritime University Chabahar Iran

Serum biochemical parameters are important aspects in the management of endangered species. The values of these parameters can be used for confirming the maturity and for monitoring any changes in the quality of waters and related soils. The aim of this research was to determine the reference values of biochemical factors in Acantopagrus latus and Epinephelus coioides. Blood samples were collected from captured fish from coastal waters of Chabahar (Ramin waterfront). Serum levels of glucose, Blood Urea Nitrogen (BUN), cholesterol (CHO), triglyceride, total protein, albumin, calcium (Ca2+), phosphorus (P), sodium (Na+), bilirubin and potassium (K+) were measured. The results showed that the levels of albumin and bilirubin in E. coioides were significantly higher than A. latus and there were significant differences in all of the serum values (except P and glucose) between A. latus and E. coioides (P < 0.05). It can be concluded that the values of blood biochemical parameters may be affected by physiological factors such as the species of fish.

关键词： Serum Acantopagrus latus Epinephelus coioides Electrolyte Non Electrolyte

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Modified activated carbons with amino groups and their copper adsorption properties in aqueous solution

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Chinese Journal of Chemical Engineering 2015年第1期23卷 50-56页

作者： Mohammad Hassan Mahaninia paria Rahimian Tahereh Kaghazchi Department of Chemistry University of Saskatchewan Department of Textile Engineering Amirkabir University of Technology Department of Chemical Engineering Amirkabir University of Technology

Activated carbons were prepared by two chemical methods and the adsorption of Cu(II) on activated carbons from aqueous solution containing amino groups was studied. The first method involved the chlorination of activated carbon following by substitution of chloride groups with amino groups, and the second involved the nitrilation of activated carbon with reduction of nitro groups to amino groups. Resultant activated carbons were characterized in terms of porous structure, elemental analysis, FTIR spectroscopy, XPS, Boehm titration,and p Hzpc. Kinetic and equilibrium tests were performed for copper adsorption in the batch mode. Also,adsorption mechanism and effect of p H on the adsorption of Cu(II) ions were discussed. Adsorption study shows enhanced adsorption for copper on the modified activated carbons, mainly by the presence of amino groups, and the Freundlich model is applicable for the activated carbons. It is suggested that binding of nitrogen atoms with Cu(II) ions is stronger than that with H+ions due to relatively higher divalent charge or stronger electrostatic force.

关键词： Activated carbon Amino groups Cu(II) adsorption Freundlich model

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Prevalence of cryptosporidiosis in animals in Iran: A systematic review and meta-analysis

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Asian Pacific Journal of Tropical Medicine 2021年第3期14卷 99-112页

作者： Mohammad Jokar Mohammad Hasan Rabiee Saied Bokaie Vahid Rahmanian paria Dehesh Hamideh Hasannejad Kiavash Hushmandi Hadi Keshipour Faculty of Veterinary Medicine Karaj BranchIslamic Azad UniversityKarajIran Divisions of Epidemiology Department of Food Hygiene and Quality ControlFaculty of Veterinary MedicineUniversity of TehranIran Zoonoses Research Center Jahrom University of Medical SciencesJahromIran Department of Epidemiology School of Public HealthIran University of Medical SciencesTehranIran

Objective:To review the prevalence of cryptosporidiosis among animal population of ***:Data were systematically gathered from 1 January 2000 to 1 January 2020 in the Islamic Republic of Iran from the following electronic databases:Pub Med,Springer,Google Scholar,Science Direct,Scopus,Web of Science,Magiran,and Scientific Information Database(SID).According to the preferred reporting items for systematic reviews and meta-analyses(PRISMA)and inclusion criteria,88 eligible studies were ***:The pooled prevalence of cryptosporidiosis using random and fixed effects model according to heterogeneity among animals was as follows:rodents 18.8%(95%CI 12.6%-25.0%),camels 17.1%(95%CI 8.6%-25.7%),cattle 16.8%(95%CI 13.4%-20.1%),goats 14.1%(95%CI 5.2%-23.0%),horses 12.2%(95%CI 8.3%-16.2%),birds 10.5%(95%CI 7.6%-13.4%),sheep 9.9%(95%CI 2.4%-4.9%),cats 8.8%(95%CI 4.8%-12.8%)and dogs 3.7%(95%CI 7.0%-12.8%).Conclusions:Cryptosporidiosis has been reported and present in a wide range of animals in Iran over the years and has a high prevalence in most of these species.

关键词： Cryptosporidiosis Animals Prevalence Iran

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