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Vegetation-environment relationship in conifer dominating forests of the mountainous range of Indus Kohistan in northern Pakistan

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Journal of Mountain Science 2020年第8期17卷 1989-2000页

作者： Adam KHAN Moinuddin AHMED Muhammad Faheem SIDDIQI Mohib shah Eduardo Soares CALIXTO Afsheen KHAN paras shah Javed IQBAL Muhammad AZEEM Department of Botany University of BunerSwari 19290Pakistan Dr.Moinuddin Ahmed Research Laboratory of Dendrochronology and Plant Ecology Department of Botany FederalUrdu University of ArtsScience and Technology Gulshan-e-Iqbal campus KarachiKarachi 75300Pakistan Department of Botany University of Karachi Karachi 75270Pakistan Department of Botany Abdul Wali Khan University MardanMardan 23200Pakistan Department of Entomology University of Sao PauloRibeirao PretoRibeirao Preto 14040-900Brazil Dr.Abdul Ghaffar laboratory of Plant Pathology and Aerobiology Department of BotanyFederal Urdu University ofArtsScience and Technology Gulshan-e-Iqbal campus KarachiKarachi 75300Pakistan

Environmental variables play a crucial role in shaping vegetation structure,mainly in mountainous *** studies have attempted to identify the environment-vegetation relationship of Conifer Dominating Forests(CDF)***,due to differences in local climate and soil composition,different environmental drivers can be *** applying multivariate analysis techniques,this study investigated the vegetation-environment relationship of CDF of Indus Kohistan in northern *** results showed that CDF of Indus Kohistan are distributed in five distinct ecological groups,which are dominated by different trees and understory species.A total of 7 trees and 71 understory species were recorded from the sampling *** deodara was the leading species among four groups,having the highest importance value(IV),density and basal *** I was dominated by Pinus wallichiana with the second highest importance value,density and basal *** addition,elevation,slope,maximum water holding capacity(MWHC),soil moisture(SM),total organic matter(TOM),sodium,phosphorus and nickel showed highly significant influence on composition and distribution pattern of Indus Kohistan ***,this study shows a new evidence of vegetation-environment relationship,pointing out specific drivers of vegetation structure in CDF of Indus Kohistan region in northern Pakistan.

关键词： Conifer forests Understory species Environmental variables Multivariate analysis Indus Kohistan Northern Pakistan

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Multi-parametric MRI of the prostate:Factors predicting extracapsular extension at the time of radical prostatectomy

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Asian Journal of Urology 2017年第1期4卷 31-36页

作者： Geoffrey S.Gaunay Vinay Patel paras shah Daniel Moreira Ardeshir R.Rastinehad Eran Ben-Levi Robert Villani Manish A.Vira The Smith Institute for Urology Hofstra Northwell School of MedicineNew Hyde ParkNYUSA Department of Urology Mayo ClinicRochesterMNUSA Department of Urology Icahn School of Medicine at Mount SinaiNew YorkNYUSA Department of Radiology Hofstra Northwell School of MedicineNew Hyde ParkNYUSA

Objective:Extracapsular extension(ECE)of prostate cancer is a poor prognostic factor associated with progression,recurrence after treatment,and increased prostate cancer-related *** staging prior to radical prostatectomy is crucial in avoidance of positive margins and when planning nerve-sparing ***-parametric magnetic resonance imaging(mpMRI)of the prostate has shown promise in this regard,but is hampered by poor *** sought to identify additional clinical variables associated with pathologic ECE and determine our institutional accuracy in the detection of ECE amongst patients who went on to radical ***:mpMRI studies performed between the years 2012 and 2014 were cross-referenced with radical prostatectomy *** properties of ECE as well as additional clinical and biochemical variables to identify pathology-proven prostate cancer ECE were ***:The prevalence of ECE was 32.4%,and the overall accuracy of mpMRI for ECE was 84.1%.Overall mpMRI sensitivity,specificity,positive predictive value,and negative predictive value for detection of ECE were 58.3%,97.8%,93.3%,and 81.5%,*** mpMRI characteristics predictive of pathologic ECE included primary lesion size((20.73±9.09)mm,mean±SD,p<0.001),T2 PIRADS score(p=0.009),overall primary lesion score(p<0.001),overall study suspicion score(p=0.003),and MRI evidence of seminal vesicle invasion(SVI)(p=0.001).

关键词： Prostate cancer Magnetic resonance imaging Staging Prostatectomy Extracapsular extension

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Role of multi-parametric MRI of the prostate for screening and staging:Experience with over 1500 cases

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Asian Journal of Urology 2017年第1期4卷 68-74页

作者： Geoffrey Gaunay Vinay Patel paras shah Daniel Moreira Simon J.Hall Manish A.Vira Michael Schwartz Jessica Kreshover Eran Ben-Levi Robert Villani Ardeshir Rastinehad Lee Richstone Department of Urology The Smith Institute for UrologyNorthwell HealthNew Hyde ParkNYUSA Department of Urology University of Illinois ChicagoChicagoILUSA Department of Urology&Interventional Radiology Mount Sinai Health SystemNew York CityNYUSA

Objective:Contemporary prostate cancer(PCa)screening modalities such as prostate specific antigen(PSA)and digital rectal examination(DRE)are limited in their ability to predict the detection of clinically significant ***-parametric magnetic resonance imaging(mpMRI)of the prostate has been explored as a staging modality for *** is known regarding its utility as a primary screening *** examined our experience with mpMRI as both a screening and staging ***:mpMRI studies performed between 2012 and 2014 in patients without PCa were cross-referenced with transrectal ultrasonography(TRUS)biopsy *** analyses were performed to determine association of mpMRI findings with overall cancer diagnoses and clinically significant(Gleason score≥7)*** analyses were then performed on patients with a history of prior negative biopsy and those without a history of TRUS *** studies were also cross-referenced with RP *** analyses determined predictive ability of extracapsular extension(ECE),seminal vesicle involvement(SVI),and pathologic evidence of clinically significant disease(Gleason score7).Results:Four hundred biopsy naive or prior negative biopsy patients had positive mpMRI *** sensitivity,specificity,positive and negative predictive values were 94%,37%,58%,and 87%,respectively and 95%,31%,42%,and 93%,respectively for overall cancer detection and Gleason score≥7 *** patients with no prior biopsy history,mpMRI sensitivity,specificity,positive and negative predictive values were 94%,36%,65%,and 82%,for all cancers,and 95%,30%,50%,and 89%for Gleason score7 lesions,*** those with prior negative biopsy sensitivity,specificity,positive and negative predictive values were 94%,37%,52%,and 90% for all cancers,and 96%,32%,36%,and 96% for Gleason score7 lesions,***-four patients underwent radical prostatectomy(RP)after *** size on mpMRI corr

关键词： Prostate cancer Magnetic resonance imaging Staging Prostatectomy Screening Margins Gleason score Novel use

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Mesenteric vein thrombosis in a patient heterozygous for factor Ⅴ Leiden and G20210A prothrombin genotypes

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World Journal of Gastroenterology 2013年第43期19卷 7813-7815页

作者： paras Karmacharya Madan Raj Aryal Anthony Donato Department of Internal Medicine Reading Health SystemWest ReadingPA 19611United States

Mesenteric venous thrombosis(MVT)is a rare but life threatening form of bowel *** is implicated in 6%-9% of all cases of acute mesenteric *** proportion of patients with primary(or idiopathic)MVT varies from 0% to 49%,with a decrease in frequency secondary to more recent availability of newer investigations for *** presence of factor Ⅴ Leiden(FVL)and prothrombin G20210A mutations(PGM)have been well documented in these ***,there have been scarce case reports describing MVT in heterozygotes of both these mutations occurring simultaneously and its implications on long term *** case describes acute MVT in a previously asymptomatic young patient with no prior history of venous *** patient was found to be heterozygous for FVL and PGM and treated with lifelong anticoagulation with warfarin(goal international normalized ratio:2-3)and avoidance of hormonal contraceptives.

关键词： Mesenteric vein thrombosis Prothrombin gene Factor Ⅴ Leiden Heterozygous Anticoagulation Oral contraceptives

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Fluorescence lifetime imaging for studying DNA compaction and gene activities

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Light(Science & Applications) 2021年第12期10卷 2349-2359页

作者： Svitlana M.Levchenko Artem Pliss Xiao Peng paras N.Prasad Junle Qu Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Physics and Optoelectronic EngineeringShenzhen UniversityShenzhenGuangdong 518060China Department of Cell Biophysics Faculty of BiochemistryBiophysics and BiotechnologyJagiellonian University30-387 KrakowPoland Institute for Lasers Photonics and BiophotonicsUniversity at BuffaloState University of New YorkBuffaloNY 14260-3000USA

Optical imaging is a most useful and widespread technique for the investigation of the structure and function of the cellular ***,an analysis of immensely convoluted and irregularly compacted DNA polymer is highly challenging even by modern super-resolution microscopy *** we propose fluorescence lifetime imaging(FLIM)for the advancement of studies of genomic structure including DNA compaction,replication as well as monitoring of gene *** proposed FLIM assay employs two independent mechanisms for DNA compaction *** mechanism relies on the inverse quadratic relation between the fluorescence lifetimes of fluorescence probes incorporated into DNA and their local refractive index,variable due to DNA compaction *** mechanism is based on the Förster resonance energy transfer(FRET)process between the donor and the acceptor fluorophores,both incorporated into *** these proposed mechanisms were validated in cultured *** obtained data unravel a significant difference in compaction of the gene-rich and gene-poor pools of genomic *** show that the gene-rich DNA is loosely compacted compared to the dense DNA domains devoid of active genes.

关键词： expression. lifetime donor

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Multi-Objective High-Fidelity Optimization Using NSGA-III and MO-RPSOLC

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Computer Modeling in Engineering & Sciences 2021年第11期129卷 443-464页

作者： N.Ganesh Uvaraja Ragavendran Kanak Kalita paras Jain Xiao-Zhi Gao Department of Computer Science and Engineering Vel Tech Multi Tech Dr.Rangarajan Dr.Sakunthala Engineering CollegeChennai600062India Department of Electronics and Telecommunication Engineering MPSTME SVKM’S Narsee Monjee Institute of Management StudiesShirpur425405India Department of Mechanical Engineering Vel Tech Rangarajan Dr.Sagunthala R&D Institute of Science and TechnologyAvadi600062India School of Computing Science and Engineering VIT Bhopal UniversitySehore466114India School of Computing University of Eastern FinlandKuopio70211Finland

Optimizing the performance of composite structures is a real-world application with significant *** this paper,a high-fidelity finite element method(FEM)is combined with the iterative improvement capability of metaheuristic optimization algorithms to obtain optimized composite *** FEM module comprises of ninenode isoparametric plate bending element in conjunction with the first-order shear deformation theory(FSDT).A recently proposed memetic version of particle swarm optimization called RPSOLC is modified in the current research to carry out multi-objective Pareto *** performance of the MO-RPSOLC is found to be comparable with the *** work successfully highlights the use of FEM-MO-RPSOLC in obtaining highfidelity Pareto solutions considering simultaneous maximization of the fundamental frequency and frequency separation in laminated composites by optimizing the stacking sequence.

关键词： Composites finite element optimization Pareto swarm intelligence

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Automated Identification Algorithm Using CNN for Computer Vision in Smart Refrigerators

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Computers, Materials & Continua 2022年第5期71卷 3337-3353页

作者： Pulkit Jain paras Chawla Mehedi Masud Shubham Mahajan Amit Kant Pandit Chandigarh University Mohali140413India Department of Computer Science College of Computers and Information TechnologyTaif UniversityTaif21944Saudi Arabia School of Electronics&Communication Engineering Shri Mata Vaishno Devi UniversityKatra182320India

Machine Learning has evolved with a variety of algorithms to enable state-of-the-art computer vision *** particular the need for automating the process of real-time food item identification,there is a huge surge of research so as to make smarter *** to a survey by the Food and Agriculture Organization of the United Nations(FAO),it has been found that 1.3 billion tons of food is wasted by consumers around the world due to either food spoilage or expiry and a large amount of food is wasted from homes and restaurants *** refrigerators have been very successful in playing a pivotal role in mitigating this problem of food *** a major issue is the high cost of available smart refrigerators and the lack of accurate design algorithms which can help achieve computer vision in any ordinary *** address these issues,this work proposes an automated identification algorithm for computer vision in smart refrigerators using InceptionV3 and MobileNet Convolutional Neural Network(CNN)*** designed module and algorithm have been elaborated in detail and are considerably evaluated for its accuracy using test images on standard fruits and vegetable datasets.A total of eight test cases are considered with accuracy and training time as the performance *** the end,real-time testing results are also presented which validates the system’s performance.

关键词： CNN computer vision Internet of Things(IoT) radio frequency identification(RFID) graphical user interface(GUI)

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Inflammation and dry eye disease——where are we?

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International Journal of Ophthalmology(English edition) 2022年第5期15卷 820-827页

作者： Srinivas K Rao Rishi Mohan Nikhil Gokhale Himanshu Matalia paras Mehta Darshan Eye Care&Surgical Centre ChennaiTamil NaduIndia MM Eyetech Institute of Ophthalmology New DelhiIndia Gokhale Eye Hospital MumbaiMaharashtraIndia Narayana Nethralaya Electronic CityBangaloreKarnatakaIndia Sameep Eye Hospital and Corneal Center VadodaraGujaratIndia

The presence of inflammation in dry eye disease(DED)results in increased patient symptomatology,ocular surface damage and worsening tear *** also affects the health of meibomian glands and their secretions which further aggravates ocular surface *** article reviews current knowledge regarding ocular surface inflammation in DED and explores the relationships between the vicious cycles of DED,inflammation and meibomian gland dysfunction(MGD).The clinical evaluation of eyes with such changes,markers that identify the presence of inflammation on the ocular surface and current treatment options are discussed.

关键词： dry eye disease inflammation meibomian gland dysfunction vicious cycle ocular surface disease

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Overexpression of Slug is associated with malignant progression of esophageal adenocarcinoma

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World Journal of Gastroenterology 2008年第7期14卷 1044-1052页

作者： paras Jethwa Mushal Naqvi Robert G Hardy Neil A Hotchin Sally Roberts Robert Spychal Chris Tselepis CRUK Institute for Cancer Studies University of BirminghamUnited Kingdom Department of Clinical and Surgical Sciences Royal Infirmary of EdinburghUnited Kingdom School of Biosciences University of BirminghamUnited Kingdom Sandwell and West Birmingham Hopsitals NHS Trust BirminghamUnited Kingdom

AIM: To characterise expression of known E-cadherin repressors; Snail, Slug and Twist in the development of esophageal adenocarcinoma. METHODS: E-cadherin, Slug, Snail and Twist mRNA expression in Barrett's metaplasia and esophageal adenocarcinoma specimens was examined by real-time reverse transcription-polymerase chain reaction (RT-PCR). Semi-quantitative immunohistochemistry was used to examine cellular localisation and protein levels. The effect of Slug on epithelial mesenchymal transition (EMT) markers was examined by transfection of Slug into an adenocarcinoma line ***: Cellular localisation of Slug in Barrett's metaplasia was largely cytoplasmic whilst in adenocarcinoma it was nuclear. Semi-quantitative analysis indicated that Slug was more abundant in adenocarcinoma compared to matched Barrett's metaplastic specimens. Snail and Twist were expressed in adenocarcinoma but were cytoplasmic in location and not induced compared to Barrett's mucosa. These observations were supported by mRNA studies where only Slug mRNA was shown to be over-expressed in adenocarcinoma and inversely correlated to E-cadherin expression. Overexpression of Slug in OE33 mediated E-cadherin repression and induced the mesenchymal markers vimentin and ***: Progression to adenocarcinoma is associated with increased Slug expression and this may represent a mechanism of E-cadherin silencing.

关键词： Slug Oesophagus Cancer Barrett's metaplasia Epithelial-mesenchymal transition

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Conservative management of type 2 gallbladder perforation in a child

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World Journal of Clinical Cases 2015年第7期3卷 671-674页

作者： Vishesh Dikshit Rahul Gupta paras Kothari Abhaya Gupta Ravikiran Kamble Krushnakumar Kesan Department of Pediatric Surgery Lokmanya Tilak Municipal General Hospital and Medical CollegeSion Hospital

Gallbladder perforation(GBP) is a rare but serious complication of cholecystitis and needs to be managed promptly. Acalculus cholecystitis leading to GBP is frequently associated with enteric fever and found in critically ill patients, and a surgical approach is not always feasible in such patients. Use of percutaneous tube cholecystostomy(PTC) in such patients is a known entity but it is usually followed by interval cholecystectomy. Here we report a case of perforated gallbladder in a child managed conservatively and successfully with PTC as the definitive treatment wherein cholecystectomy was avoided. The functionality of the gallbladder was confirmed by a Tc99m-HIDA scan.

关键词： Spontaneous Gallbladder Perforation Percutaneous tube cholecystostomy

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