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What controls PTEN and what it controls （in prostate cancer）

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Asian Journal of Andrology 2012年第1期14卷 130-131页

作者： paramita m.ghosh Department of Urology and Department of Biochemistry and molecular medicine University of California Davis Sacramento CA 95817 USA and Research Services VA Northern California Health Care System Mather CA 95655 USA

The standard of care for metastatic prostate cancer （PCa） is androgen deprivation therapy since almost all PCa growth is initially reliant on the androgen receptor （AR）. However, almost all patients develop resistance to this therapy within 18-24 months, and current treatment for castration-resistant prostate cancer （CRPC） is extremely limited, despite the advent of new drugs that target the AR,

关键词： Health care Outcomes research Paediatric rheumatic diseases Spondyloarthritis

Finite size effect on dissociation and diffusion of chiral partners in Nambu-Jona-Lasinio model

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Chinese Physics C 2022年第4期46卷 114-122页

作者： paramita Deb Sabyasachi ghosh Jai Prakash Santosh Kumar Das Raghava Varma Department of Physics Indian Institute of Technology BombayPowaiMumbai-400076India Indian Institute of Technology Bhilai GEC CampusSejbaharRaipur-492015ChhattisgarhIndia School of Physical Sciences Indian Institute of Technology GoaPonda-403401GoaIndia

The masses of pion and sigma meson modes,along with their dissociation in the quark medium,provide detailed spectral structures of the chiral *** has been observed in pA and pp systems both at LHC and *** this research,we studied the restoration of chiral symmetry by investigating the finite size effect on the detailed structure of chiral partners in the framework of the Nambu-Jona-Lasinio *** diffusion and conduction have been studied using this dissociation *** is determined that the masses,widths,diffusion coefficients,and conductivities of chiral partners merge at different temperatures in the restoration phase of chiral ***,merging points are shifted to lower temperatures when finite size effect is introduced into the *** strengths of diffusions and conductions are also reduced once the finite size is introduced in the calculations.

关键词： heavy-ion collisions quark gluon plasma effective QCD

COVID-19 strict lockdown impact on urban air quality and atmospheric temperature in four megacities of India

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Geoscience Frontiers 2022年第6期13卷 279-290页

作者： Subodh Chandra Pal Indrajit Chowdhuri Asish Saha manoranjan ghosh paramita Roy Biswajit Das Rabin Chakrabortty manisa Shit Department of Geography The University of BurdwanBardhaman713104West BengalIndia Center for Rural Development and Innovative Sustainable Technology Indian Institute of Technology KharagpurWest Bengal721302India India Smart Cities Fellow National Institute of Urban AffairsNew Delhi110003India Department of Geography Raiganj UniversityRaiganjUttar Dinajpur733134West BengalIndia

COVID-19 pandemic has forced to lockdown entire India starting from 24th march 2020 to 14th April 2020(first phase), extended up to 3rd may 2020(second phase), and further extended up to 17th may 2020(third phase) with limited relaxation in non-hotspot areas. This strict lockdown has severely curtailed human activity across India. Here, aerosol concentrations of particular matters(Pm) i.e., Pm,Pm, carbon monoxide(CO), nitrogen dioxide(NO), sulphur dioxide(SO), ammonia(NH) and ozone(O), and associated temperature fluctuation in four megacities(Delhi, mumbai, Kolkata, and Chennai)from different regions of India were investigated. In this pandemic period, air temperature of Delhi,Kolkata, mumbai and Chennai has decreased about 3 ℃, 2.5 ℃, 2 ℃ and 2 ℃ respectively. Compared to previous years and pre-lockdown period, air pollutants level and aerosol concentration(-41.91%,-37.13%,-54.94% and-46.79% respectively for Delhi, mumbai, Kolkata and Chennai) in these four megacities has improved drastically during this lockdown period. Emission of Pmhas experienced the highest decrease in these megacities, which directly shows the positive impact of restricted vehicular movement. Restricted emissions produce encouraging results in terms of urban air quality and temperature, which may encourage policymakers to consider it in terms of environmental sustainability.

关键词： COVID-19 Aerosol Air pollutant Climate megacity

S-adenosyl-L-methionine, trehalose and oleanolic acid in few plants

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Health 2010年第8期2卷 968-972页

作者： Dipankar malakar paramita Chaudhuri Trina Dutta Anil K ghosh 不详

S-Adenosyl-L-methionine (Adomet), S-Adenosyl- L-Homocysteine (AdoHcy), adenosine, trehalose and oleanolic acid were measured in six medicinal herbs and three spices. The findings showed that Adomet content was forty six fold higher in the leaves of Catharanthus roseus as compared with average Adomet content of rest of the plants. In comparison to other plants, Withania somnifera had very high AdoHcy: Ado-met and adenosine: Adomet ratios indicating it may have contained high Adomet. Trehalose was found to be twenty fold and nine fold higher in bulb of Allium cepa and root of Withania somnifera respectively with respect to average trehalose content of rest of the plants. Ocimum sanctum appeared to be a rich source of oleanolic acid. It appeared from our study that Catharanthus roseus, Allium cepa and Ocimum sanctum could be utilized as natural sources of Adomet, trehalose and oleanolic acid respectively.

关键词： Adomet AdoHcy Adenosine Trehalose Oleanolic Acid

Experiment and simulation to determine the optimum orientation of building-integrated photovoltaic on tropical building façades considering annual daylight performance and energy yield

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Energy and Built Environment 2024年第3期5卷 414-425页

作者： Rizki A.mangkuto Dhian Nur Aziz T.Tresna Ikhwan m.Hermawan Justin Pradipta Nurul Jamala Beta paramita Atthaillah Building Physics Research Group Faculty of Industrial TechnologyInstitut Teknologi BandungLabtek VIJl.Ganesha 10Bandung 40132Indonesia Engineering Physics Program Faculty of Industrial TechnologyInstitut Teknologi BandungLabtek VIJl.Ganesha 10Bandung 40132Indonesia Engineering Physics Research Group Faculty of Industrial TechnologyInstitut Teknologi BandungLabtek VIJl.Ganesha 10Bandung 40132Indonesia Department of Architecture Faculty of EngineeringHasanuddin UniversityJl.Poros Malino Km.6Gowa 92171Indonesia Architecture Study Program Faculty of Technology and Vocational EducationUniversitas Pendidikan IndonesiaJl.Dr.Setiabudhi 229Bandung 40152Indonesia Architecture Program Faculty of EngineeringUniversitas MalikussalehJl.Cot Teungku NieAceh Utara 24355Indonesia

Building-Integrated Photovoltaic(BIPV)on vertical façades is a potential PV application in today’s *** performance of BIPV on façades is significantly influenced by the façade *** tropical cities,the optimum façade orientation,in terms of maximum energy yield and daylight performance,cannot be simply determined,due to relatively symmetrical sun path throughout the *** study therefore aims to determine the optimum orientation for BIPV on tropical building faç*** achieve the objective,experiment,modelling,and computational simulation are conducted to evaluate the BIPV energy yield and to predict the indoor daylight performance in a scale-model building with a 105Wp monocrystalline silicon PV,facing each cardinal orienta-tion in Bandung,*** South orientation yields practically zero ASE_(1000,250),providing the best annual daylight performance,and yielding the most desirable value in four out of five daylight *** greatest annual energy yield is at the North orientation,providing 179-186 kWh(95%prediction interval)per year,but with larger uncertainty compared to that at the South,due to direct sunlight *** on three different objective functions,the South orientation is considered optimum for placing the BIPV panel on the prototype façade in the location.

关键词： Building-integrated photovoltaic Orientation Daylight metric Energy yield Tropical building façade