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Multi-temporal modeling of road-induced overland flow alterations in a terraced landscape characterized by shallow landslides

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International Soil and Water Conservation Research 2022年第2期10卷 240-253页

作者： Luca Mauri Eugenio Straffelini paolo Tarolli Department of Land EnvironmentAgriculture and ForestryUniversity of PadovaAgripolisViale Dell’Università 1635020Legnaro(PD)Italy

The presence of roads in high steep agricultural systems is often linked with landslides *** research aims to model multi-temporal overland flow dynamics in a shallow landslides-prone terraced landscape(northern Italy).The combined use of Remotely Piloted Aircraft Systems(RPAS)and photo-grammetric techniques(e.g.,Structure from Motion-SfM)allowed to elaborate multi-temporal high-resolution Digital Elevation Models(DEMs).Hydrological analyses of water flow's depth alterations due to the road presence were carried out adopting the SIMulated Water Erosion model(SIMWE),focusing on different scenarios considering the presence of the road and assuming its absence through a specific DEM smoothing *** possibility to perform multi-temporal hydrological simulations at a hillslope scale so as to analyse the role played by the road in overland flows alteration is still a challenge to be *** proved the role played by the road in water flows change above the two observed shallow landslides,with respective maximum water depth values equal to 0.18 m and 0.14 *** the contrary,no-road simulations not revealed significant water flows deviations towards landslides,with water depth values around 0 m,underlining that the absence of the road would avoid relevant changes in water flow paths toward the collapsed *** work could be a solid starting point for analyse road impact on runoff dynamics and hillslopes stability also at a wider scale,as well as for planning efficient mitigation intervention so as to reduce the occurrence of similar future scenarios.

关键词： Terraced landscape Road Landslide Remote sensing DEM

Data trustworthiness and user reputation as indicators of VGI quality

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Geo-Spatial Information Science 2018年第3期21卷 213-233页

作者： paolo Fogliaroni Fausto D’Antonio Eliseo Clementini Department for Geodesy and Geoinformation Vienna University of TechnologyViennaAustria Department of Industrial and Information Engineering and Economics University of L’AquilaL’AquilaItaly

Volunteered geographic information(VGI)has entered a phase where there are both a substantial amount of crowdsourced information available and a big interest in using it by *** the issue of deciding the quality of VGI without resorting to a comparison with authoritative data remains an open *** article first formulates the problem of quality assessment of VGI *** presents a model to measure trustworthiness of information and reputation of contributors by analyzing geometric,qualitative,and semantic aspects of edits over *** implementation of the model is running on a small data-set for a preliminary empirical *** results indicate that the computed trustworthiness provides a valid approximation of VGI quality.

关键词： Volunteered geographic information data quality trustworthiness reputation

Three-dimensional in vitro models of neuromuscular tissue

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Neural Regeneration Research 2022年第4期17卷 759-766页

作者： paolo Raffa Maria Easler Anna Urciuolo Institute of Pediatric Research IRP PadovaItaly Molecular Medicine Department University of PadovaPadovaItaly

Skeletal muscle is a dynamic tissue in which homeostasis and function are guaranteed by a very defined three-dimensional organization of myofibers in respect to other nonmuscular components,including the extracellular matrix and the nervous *** particular,communication between myofibers and the nervous system is essential for the overall correct development and function of the skeletal muscle.A wide range of chronic,acute and genetic-based human pathologies that lead to the alteration of muscle function are associated with modified preservation of the fine interaction between motor neurons and myofibers at the neuromuscular *** advancements in the development of in vitro models for human skeletal muscle have shown that three-dimensionality and integration of multiple cell types are both key parameters required to unveil pathophysiological relevant ***,we describe recent achievement reached in skeletal muscle modeling which used biomaterials for the generation of three-dimensional constructs of myotubes integrated with motor neurons.

关键词： 3D organization bioengineering biomaterials motor neurons neuromuscular junction skeletal muscle models

Variations in porcine colostrum oligosaccharide composition between breeds and in association with sow maternal performance

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Journal of Animal Science and Biotechnology 2020年第3期11卷 830-840页

作者： paolo Trevisi Diana Luise Savanna Won Jaime Salcedo Micol Bertocchi Daniela Barile paolo Bosi Department of Agricultural and Food Sciences University of BolognaViale G.Fanin 4640127 BolognaItaly Department of Food Science and Technology University of California-DavisOne Shields AvenueDavisCA 95616USA

Background:Oligosaccharides(OS)are indigestible carbohydrates naturally found in *** composition of porcine colostrum OS may influence the growth and the health of the neonate and consuming optimal concentrations of OS may reduce piglet susceptibility to *** this manner,targeted supplementation of animal feed with OS is being explored as a health management tool in the livestock *** variation in OS composition between different breeds of pig and its association with the litter performance is currently *** aim of this study was to characterize the colostrum OS composition from sows of different breed and parity and correlate this data with sow maternal ***:Eighty-three colostrum samples from parities 1 to 8 were gathered from 3 different breeds of sow:44 Large White sows,27 Landrace sows and 12 Duroc *** were taken between the birth of the first and the last piglet from sows that were not pharmacologically induced to *** were purified from the samples and analysed by MALDI-ToF mass spectrometry(21 OS compositions detected).The farrowing season and the maternal data were recorded for each sow,including the number of live piglets and the litter body weight at birth,at day(d)3 and at ***:Five OS compositions,including isomers of the bifidogenic Sialyllactose,Lacto-N-Tetraose and Lacto-NHexaose series,were detected in all the *** other OS were identified in at least 50%of samples,and their abundances were affected by breed(P<0.05;6 of 12),marginally affected by season(P<0.10;3 of 12)and never by parity *** abundances of each OS component were standardized by Z-score scaling(μ=0 and SD=1),transformed by principal component analysis,and four similarity clusters were *** membership was associated with litter weight gain within 3 days(P=0.063)and at weaning(P<0.05),but not with piglet mortality within 3 ***:OS composition of colostrum may partially explain the vari

关键词： MALDI-ToF analysis Milk Nutrient composition Pig breeds Piglet survival

REALISTIC AND CORRECT MODELS OF IMPRESSED SOURCES FOR TIME-HARMONIC ELECTROMAGNETIC BOUNDARY VALUE PROBLEMS INVOLVING METAMATERIALS

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International Journal of Modeling, Simulation, and Scientific Computing 2013年第3期4卷 97-148页

作者： paolo FERNANDES MIRCO RAFFETTO Istituto di Matematica Applicata e Tecnologie Informatiche del Consiglio Nazionale delle Ricerche Via De Marini 6 I-16149 GenoaItaly Department of Biophysical and Electronic Engineering University of Genoa Via Opera Pia 11a I-16145GenoaItaly

The aim of this work is to analyze the role of the impressed sources in determining the well or ill-posedness of time harmonic electromagnetic boundary value problems involving isotropic effective *** is shown,in particular,that,even if all interfaces are regular,the class of ill-posed problems can be very large in the presence of general square-integrable impressed ***,when a simple and realistic constraint is enforced on these sources,requiring that the support of the sources does not include any interface between a traditional medium and a metamaterial,among the problems here considered just those involving an interface between complementary materials remain *** considerations have a very significant impact also on the approximability of the solution of well-posed problems since the numerical noise can introduce small fictitious sources even where the sources to be simulated are not *** effects on finite element simulators are fully ***,we propose an algorithm that allows to obtain much better approximations of the solutions of the most critical wellposed problems.

关键词： Time-harmonic electromagnetic boundary value problems electromagnetic modeling of composite media waveguide discontinuity problems ill-posedness metamaterials electromagnetic simulators finite element methods.

Clinical management of inflammatory bowel disease in the organ recipient

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World Journal of Gastroenterology 2014年第13期20卷 3525-3533页

作者： Amedeo Indriolo paolo Ravelli Digestive Endoscopy Unit Department of GastroenterologyPapa Giovanni XXIII Hospital24127 BergamoItaly

There was estimated a higher incidence of de novo inflammatory bowel disease (IBD) after solid organ transplantation than in the general population. The onset of IBD in the organ transplant recipient population is an important clinical situation which is associated to higher morbidity and difficulty in the medical therapeutic management because of possible interaction between anti-reject therapy and IBD therapy. IBD course after liver transplantation (LT) is variable, but about one third of patients may worsen, needing an increase in medical therapy or a colectomy. Active IBD at the time of LT, discontinuation of 5-aminosalicylic acid or azathioprine at the time of LT and use of tacrolimus-based immunosuppression may be associated with an unfavorable outcome of IBD after LT. Anti-tumor necrosis factor alpha (TNFα) therapy for refractory IBD may be an effective and safe therapeutic option after LT. The little experience of the use of biological therapy in transplanted patients, with concomitant anti-rejection therapy, suggests there be a higher more careful surveillance regarding the risk of infectious diseases, autoimmune diseases, and neoplasms. An increased risk of colorectal cancer (CRC) is present also after LT in IBD patients with primary sclerosing cholangitis (PSC). An annual program of endoscopic surveillance with serial biopsies for CRC is recommended. A prophylactic colectomy in selected IBD/PSC patients with CRC risk factors could be a good management strategy in the CRC prevention, but it is used infrequently in the majority of LT centers. About 30% of patients develop multiple IBD recurrence and 20% of patients require a colectomy after renal transplantation. Like in the liver transplantation, anti-TNFα therapy could be an effective treatment in IBD patients with conventional refractory therapy after renal or heart transplantation. A large number of patients are needed to confirm the preliminary observations. Regarding the higher clinica

关键词： Inflammatory bowel disease, Ulcerative colitis, Crohn’ s disease, Primary sclerosing cholangitis, Liver transplantation, Heart transplantation, Renal transplantation, Anti-tumor necrosis factor alpha therapy

Role of non-steroidal anti-inflammatory drugs on intestinal permeability and nonalcoholic fatty liver disease

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World Journal of Gastroenterology 2017年第22期23卷 3954-3963页

作者： erika utzeri paolo usai department of medical sciences university of cagliari

The use of non-steroidal anti-inflammatory drugs(NSAIDs) is widespread worldwide thanks to their analgesic, anti-inflammatory and antipyretic effects. However, even more attention is placed upon the recurrence of digestive system complications in the course of their use. Recent data suggests that the complications of the lower gastro-intestinal tract may be as frequent and severe as those of the upper tract. NSAIDs enteropathy is due to enterohepatic recycling of the drugs resulting in a prolonged and repeated exposure of the intestinal mucosa to the compound and its metabolites. Thus leading to so-called topical effects, which, in turn, lead to an impairment of the intestinal barrier. This process determines bacterial translocation and toxic substances of intestinal origin in the portal circulation, leading to an endotoxaemia. This condition could determine a liver inflammatory response and might promote the development of nonalcoholic steatohepatitis, mostly in patients with risk factors such as obesity, metabolic syndrome and a high fat diet, which may induce a small intestinal bacterial overgrowth and dysbiosis. This alteration of gut microbiota may contribute to nonalcoholic fatty liver disease and its related disorders in two ways: firstly causing a malfunction of the tight junctions that play a critical role in the increase of intestinal permeability, and then secondly leading to the development of insulin resistance, body weight gain, lipogenesis, fibrogenesis and hepatic oxidative stress.

关键词： Non-steroidal anti-inflammatory drugs Intestinal barrier Intestinal permeability Non-steroidal anti-inflammatory drugs - enteropathy Nonalcoholic fatty liver disease Nonalcoholic steatohepatitis Microbiota Metabolic syndrome Proton pump inhibitors Endotoxaemia

全球生活用纸设备供需变化:可持续性、能源节约和数字化

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生活用纸 2024年第5期24卷 43-51页

作者： Jenny Lahti Samuelsson paolo Raffaelli Shinji Goda Marcelo Marlon Silveira dos Santos 彭伟东 Roy Vincent Valter Canelli 维美德生活用纸拓斯克川之江设计部 Hergen工程应用技术部门宝索机械制造有限公司安德里茨北美生活用纸亚赛利纸业

在当前的经济环境下,设备高度灵活性已成为全球产业供应链应对生产时的特点,主要体现为对生产环节的持续监测和先进诊断技术、高效的数据储存、智能自动化、热电联产,以及减碳采购等措施。Tissue World杂志对全球领先的卫生纸机供应商... 详细信息

在当前的经济环境下,设备高度灵活性已成为全球产业供应链应对生产时的特点,主要体现为对生产环节的持续监测和先进诊断技术、高效的数据储存、智能自动化、热电联产,以及减碳采购等措施。Tissue World杂志对全球领先的卫生纸机供应商进行了专访,请他们分别就全球生活用纸市场的可持续能源利用及智能化设备生产技术等话题发表独到见解。

关键词：供需变化可持续能源智能自动化智能化设备数据储存生活用纸卫生纸机能源节约

Virtual earth cloud: a multi-cloud framework for enabling geosciences digital ecosystems

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International Journal of Digital Earth 2023年第1期16卷 43-65页

作者： Mattia Santoro paolo Mazzetti Stefano Nativi National Research Council of Italy Institute of Atmospheric Pollution Research-Unit of FlorenceRomaItaly Joint Research Centre of the European Commission B6 UnitIspraltaly

Humankind is facing unprecedented global environmental and social challenges in terms of food,water and energy security,resilience to natural hazards,*** address these challenges,international organizations have defined a list of policy actions to be achieved in a relatively short and medium-term *** development and use of knowledge platforms is key in helping the decision-making process to take significant decisions(providing the best available knowledge)and avoid potentially negative impacts on society and the *** knowledge platforms must build on the recent and next coming digital technologies that have transformed society–including the science and engineering *** Earth Data(BED)science aims to provide the methodologies and instruments to generate knowledge from numerous,complex,and diverse data *** science requires the development of Geoscience Digital Ecosystems(GEDs),which bank on the combined use of fundamental technology units(*** data,learning-driven artificial intelligence,and network-based computing platform)to enable the development of more detailed knowledge to observe and test planet Earth as a *** manuscript contributes to the BED science research domain,by presenting the Virtual Earth Cloud:a multi-cloud framework to support GDE implementation and generate knowledge on environmental and social sustainability.

关键词： Earth observation geosciences digital ecosystem virtual cloud big earth data multi-cloud interoperability science