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Modeling Global and Local Aspects of Spatial Structure Explicitly in Land-Use Optimization: The Case of Mek'ele City, Ethiopia

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Chinese Journal of Urban and Environmental Studies 2023年第2期11卷 66-96页

作者： Ashenafi MEHARI paolo Vincenzo GENOVESE School of Architecture Tianjin University International Center of History Critics of Architecture and Restoration of Historical Heritage (ICHCR) College of Civil Engineering and Architecture Zhejiang University

Urban spatial structure remains the center of quest and modeling. The decentralization concept is among the leading literature discourses that guide spatial analyses. In line with the decentralization discourse, the application of land-use optimization as a modeling method has grown significantly. Despite decentralization dominating the contemporary spatial analysis literature, no study so far explicitly declares an end to the centers(and subcenters). While centers(and subcenters) are alive, the land-use optimization has never taken this macro-morphological structure into consideration. This case study frames land-use optimization within the agglomeration and decentralization concepts based on the view that no single conceptual framework addresses spatial analysis sufficiently. On a theoretical level, the link is between coarse morphological assumption(basis of economic geography) and decentralization(basis of sustainable built environment). The paper blends these dual theories, one governing urban macro-morphological structures and the other governing decentralization literature. On a methodological modeling level, it blends centers and other discretized uses. Optimizing four objectives across the complete centralization through multiple centers of gravity to complete the decentralization of urban spatial structures applying Non-dominated Sorting Genetic Algorithm II, the case study findings justify the importance of explicit modeling of the macro-morphological element. It has been observed that multicenter urban forms perform well above both the single center and the dispersed scenarios. It is, therefore,argued that an appropriate approach to land-use optimization is modeling both the macro-spatial element and fine spatial elements. The result further indicates that local land-use planning regulations place the structure of city in a suboptimal state.

关键词： Land-use optimization urban form multicenter city decentralization coarse spatial scale fine spatial scale

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Deficiency of Healthcare Accessibility of Elderly People Exposed to Future Extreme Coastal Floods:A Case Study of Shanghai,China

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International Journal of Disaster Risk Science 2023年第5期14卷 840-857页

作者： Xinmeng Shan paolo Scussolini Jun Wang Mengya Li Jiahong Wen Lei Wang Key Laboratory of Geographic Information Science(Ministry of Education) East China Normal UniversityShanghai200241China Institute for National Safety and Emergency Management East China Normal UniversityShanghai200062China School of Geographic Sciences East China Normal UniversityShanghai200241China Institute for Environmental Studies Vrije Universiteit Amsterdam1081 HVAmsterdamThe Netherlands School of Public Management East China Normal UniversityShanghai200062China School of Environmental and Geographical Sciences Shanghai Normal UniversityShanghai200234China Department of Geography&Anthropology Louisiana State UniversityBaton RougeLA70803USA

Socioeconomic development,subsidence,and climate change have led to high flood risks in coastal cities,making the vulnerable,especially elderly people,more prone to ***,we mostly do not know how the accessibility of life-saving public resources for the elderly population will change under future *** Shanghai as a case,this study introduced a new analytical framework to fill this *** integrated for the first time models of coastal flooding,local population growth,and medical resource supply-demand *** results show that under an extreme scenario of coastal flooding in the year 2050,in the absence of adaptation,half of the elderly population may be exposed to floods,the supply of medical resources will be seriously insufficient compared to the demand,and the accessibility of emergency medical services will be impaired by *** methodology can be applied to gain insights for other vulnerable coastal cities,to assist robust decision making about emergency responses to flood risks for elderly populations in an uncertain future.

关键词： Coastal floods Elderly population Flood exposure analysis Healthcare accessibility Shanghai

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Towards reconstructing the Shakespeare’s first Globe Theatre: A virtual model for research and development

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Frontiers of Architectural Research 2022年第6期11卷 1104-1120页

作者： paolo Croce Francesco Leccese Mirko Mordagà Giacomo Salvadori Dept.of Energy SystemsTerritory and Construction Engineering(DESTeC)School of EngineeringUniversity of PisaPisaItaly Dept.of Civil and Industrial Engineering(DICI) School of EngineeringUniversity of PisaPisaItaly

Shakespeare’s first Globe Theatre(early 17th century)is considered one of the most iconic theatres in English history,despite lasting less than twenty years and having little information directly attributable to its shape and *** building,part of a wide variety of Elizabethan theatres found in London during a fertile period in the history of entertainment,has fascinated historians and scholars for *** in Globe Theatre has led to several attempts at reconstruction around the world in recent decades,very few of which are historically reliable due to a lack of accurate sources and the need to adapt a historic building,burnt down in a fire in 1613,to modern safety ***,with the increasing evolution of modelling systems in a virtual environment,it is now possible to analyse the theatre in a spatially and historically more consistent way with surviving *** aim of this paper is to provide a historically and constructively valid virtual model that can reopen the debate on the shapes and dimensions of Shakespeare’s first Globe *** model has been created by collecting the main hypotheses proposed by *** were used to create the basic scheme,the plans,and then the whole ***,the model was made available to encourage its use in future research and development.

关键词： Globe Theatre Historical reconstruction Virtual model Outdoor playhouses Vernacular architecture Timber-framed

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The “mitochondrial stress responses”: the “Dr. Jekyll and Mr. Hyde” of neuronal disorders

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Neural Regeneration Research 2022年第12期17卷 2563-2575页

作者： Simone Patergnani Giampaolo Morciano Marianna Carinci Sara Leo paolo Pinton Alessandro Rimessi Department of Medical Sciences Section of Experimental MedicineLaboratory for Technologies of Advanced TherapiesUniversity of FerraraFerraraItaly Center of Research for Innovative Therapies in Cystic Fibrosis University of FerraraFerraraItaly

Neuronal disorders are associated with a profound loss of mitochondrial functions caused by various stress conditions,such as oxidative and metabolic stress,protein folding or import defects,and mitochondrial DNA *** engage in different coordinated responses to safeguard mitochondrial *** this review,we will explore the contribution of mitochondrial stress responses that are activated by the organelle to perceive these dangerous conditions,keep them under control and rescue the physiological condition of nervous *** the sections to come,particular attention will be dedicated to analyzing how compensatory mitochondrial hyperfusion,mitophagy,mitochondrial unfolding protein response,and apoptosis impact human neuronal ***,we will discuss the relevance of the new concept:the“mito-inflammation”,a mitochondria-mediated inflammatory response that is recently found to cover a relevant role in the pathogenesis of diverse inflammatory-related diseases,including neuronal disorders.

关键词： Alzheimer’s disease apoptosis mitochondrial dynamics mito-inflammation mitophagy multiple sclerosis neurodegeneration Parkinson’s disease UPRmt

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New sciences&technologies in soil conservation and eco-sustainability

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International Soil and Water Conservation Research 2023年第2期11卷 412-414页

作者： paolo Tarolli Manuel EstebanLucas-Borja Guoqiang Yu Xiangzhou Xu Department of Land EnvironmentAgriculture and ForestryUniversity of PadovaAgripolisViale Dell'Universita 16LegnaroPD35020Italy School of Advanced Agricultural and Forestry Engineering Castilla La Mancha UniversityCampus Universitario s/nE-02071AlbaceteSpain Xi'an Center of Geological Survey China Geological SurveyXi'an710499China School of Hydraulic Engineering Dalian University of TechnologyDalian116024China

Soil conservation is necessary to achieve a sustainable world because soils play a crucial role in the Earth's *** the same time,the applicable and precise methods are vital to obtaining credible data in soil studies.A collection of 10 articles have been organized to focus on the new technologies regarding soil conservation and eco-sustainability and the results related to the novel *** articles put effort into the innovative works of field investigations,field experiments,model experiments,and nu-merical *** questions baffling soil scientists have been clarified and solved,and many valuable insights have been aroused.

关键词： Development Soil loss Soil conservation Eco-sustainability

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GEOSS Platform data content and use

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International Journal of Digital Earth 2023年第1期16卷 715-740页

作者： Enrico Boldrini Stefano Nativi Jiri Hradec Mattia Santoro paolo Mazzetti Max Craglia National Research Council of Italy Institute of Atmospheric Pollution ResearchFlorenceIltaly Joint Research Centre B6 UnitIspraItaly

The GEOSS Platform is a key contribution to the goal of building the Global Earth Observation System of Systems(GEOSS).It enables a harmonized discovery and access of Earth observation data,shared online by heterogeneous organizations *** work analyzes both what is made available in the GEOSS Platform by the data providers and how users are utilizing it including multiyear trends,updating a previous analysis published in *** present statistics derive from a 2021 EOValue report funded by the European *** offer of GEOSS Platform data has been the object of various analyses,including data provider characterization,data sharing trends,and data characterization(comprising metadata quality analysis,thematic analysis,responsible party identification,spatial–temporal coverage).GEOSS data demand has also been the object of several analyses,including data consumer characterization,utilization trends,and requested data characterization(comprising thematic analysis,spatial–temporal coverage,and popularity).Among thefindings,a large amount of shared data,mostly from satellite sources,emerges with an issue of low metadata quality and related discovery ***,the trend in usage is ***,the progressive disconnection of the GEOSS platform from its data Providers and Users and other possible causes are also reported.

关键词： Earth observations GEOSS System-of-Systems geospatial data quality discovery service

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Publishing China satellite data on the GEOSS Platform

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Big Earth Data 2023年第2期7卷 398-412页

作者： Roberto Roncella Lianchong Zhang Enrico Boldrini Mattia Santoro paolo Mazzetti Stefano Nativi National Research Council of Italy-Institute of Atmospheric Pollution Research Division of FlorenceFlorenceItaly Aerospace Information Research Institute Chinese Academy of SciencesBeijingChina

This paper is the first of a series that describes some of the main dataset resources presently shared through the GEOSS *** GEOSS Platform has been created to provide the technological tool to implement the Global Earth Observation System of Systems(GEOSS);it is a brokering infrastructure that presently brokers more than 190 autonomous data catalogs and information *** paper analyses the China Satellite datasets and describes the data publishing process from China GEOSS Data Provider to the GEOSS Platform considering both administrative registration as well as the technical *** China Satellite datasets are considered as one of the most important satellite data shared by the GEOSS *** analysis provides some insights as well about GEOSS user searches for China Satellite datasets.

关键词： GEOSS data interoperability data sharing satellite data Earth observation

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The allometric propagation of COVID-19 is explained by human travel

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Infectious Disease Modelling 2022年第1期7卷 122-133页

作者： Rohisha Tuladhar paolo Grigolini Fidel Santamaria Department of Biology University of Texas at San AntonioSan AntonioTX78249USA Department of Physics University of North TexasDentonTX76203USA

We analyzed the number of cumulative positive cases of COVID-19 as a function of time in countries around the *** tracked the increase in cases from the onset of the pandemic in each region for up to 150 *** found that in 81 out of 146 regions the trajectory was described with a power-law function for up to 30 *** also detected scale-free properties in the majority of sub-regions in Australia,Canada,China,and the United States(US).We developed an allometric model that was capable of fitting the initial phase of the pandemic and was the best predictor for the propagation of the illness for up to 100 *** then determined that the power-law COVID-19 exponent correlated with measurements of human *** COVID-19 exponent correlated with the magnitude of air passengers per *** correlation persisted when we analyzed the number of air passengers per US states,and even per US metropolitan ***,the COVID19 exponent correlated with the number of vehicle miles traveled in the ***,air and vehicular travel explained 70%of the variability of the COVID-19 *** together,our results suggest that the scale-free propagation of the virus is present at multiple geographical scales and is correlated with human *** conclude that models of disease transmission should integrate scale-free dynamics as part of the modeling strategy and not only as an emergent phenomenological property.

关键词： COVID-19 propagation Human mobility Power law scaling Allometric model Scalefree dynamics

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Inequity in the global distribution of monkeypox vaccines

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World Journal of Clinical Cases 2023年第19期11卷 4498-4503页

作者： Marcos Roberto Tovani-Palone Neel Doshi paolo Pedersini Department of Research Analytics Saveetha Dental College and HospitalsSaveetha Institute of Medical and Technical SciencesChennai 600077India Department of Medicine Pravara Institute of Medical SciencesAhmednagar 413736India IRCCS Fondazione Don Carlo Gnocchi Milan 20148Italy

Monkeypox(mpox)has been a public health emergency of international concern that emerged in mid-2022 and has spread to 110 *** clinical findings of the disease vary according to the seriousness of the *** its case fatality risk has not been high,a significant percentage of patients require *** this context,local initiatives were taken to extend the limited supply of vaccines against the disease;however,such measures have not been sufficient to contain the spread of cases and ensure an equitable distribution of health *** a result,endemic regions of low-income countries continue to have insufficient access to mpox *** this and considering the global scope of the disease,there is still little discussion in the literature about the difficulties in achieving adequate vaccination coverage rates for the target population of *** this article,we briefly discussed general aspects of the disease,including its surveillance,the current global context of challenges for mpox vaccination,and issues on global allocation of health resources as well as proposed related recommendations.

关键词： Monkeypox Smallpox vaccine Health inequities Vaccination coverage Vaccination hesitancy Healthcare financing

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Perihilar-cholangiocarcinoma: what really matters?

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Hepatobiliary Surgery and Nutrition 2022年第4期11卷 616-619页

作者： Fabrizio Di Benedetto paolo Magistri Stefano Di Sandro Hepato-Pancreato-Biliary Surgery and Liver Transplantation Unit University Hospital of Modena“Policlinico”University of Modena and Reggio EmiliaModenaItaly

Treatment of peri-hilar cholangiocarcinoma(PHC)is one of the most critical challenges in the modern era of liver surgery(1).In addition to the highly demanding technique and insidious diagnostic work-up,the procedure ... 详细信息

关键词： operative carcinoma liver

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