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Congenital heart diseases trends in S?o Paulo State,Brazil:a national live birth data bank analysis

World Journal of Pediatrics 2022年第7期18卷 472-481页

作者： paola soares fernandes Larissa Rosario Magalhaes Tainara Rita Pezzini Edige Felipe de Sousa Santos Mauricio Giusti Calderon Medical School Nine of July University(Uni9).Sao Bernardo do CampoSPBrazil Epidemiology Department Public Health SchoolSao Paulo University(USP)Sao PauloSPBrazil Pediatric Surgery Department Hospital Benficencia Portuguesa de Sao PauloRua Maestro Cardim768Sao PauloSP CEP 01323-011Brazil Pediatric Surgery Department Hospital Santa Catarina PaulistaAv.Paulista200.Sao PauloSP CEP:01310-000Brazil

Background Congenital heart diseases(CHD)are the most common type of birth defects,affecting millions of newborns every year;no prevalence data are available in S?o Paulo State,Brazil's most populous *** objective is to identify trends in prevalence and risk factors for CHD in Sao Paulo State,*** We developed a population-based study to estimate the CHD trend of prevalence in recent years,stratified by maternal age and geographical clusters,using all cases of CHD identified by the Live Births Information System(SINASC-Sistema de Informa??o Sobre Nascidos Vivos)from January 1,2005,to December 31,*** calculated the trends of prevalence,the regression coefficient(β),the annual percent change(APC),and 95%confidence interval using the Prais-Winsten regression model,with the Durbin-Watson *** We found 10,594 cases of CHD among 8,536,101 live births(LB),a prevalence of 12.4/10,000 *** was no difference in the sex distribution;they are primarily Caucasian(60.2%),75.2%born at term,and 74.4%weight>2500 g,66.9%of births were by cesarean section.S?o Paulo State presented an increasing CHD trend of prevalence(APC=18.9%).The highest CHD prevalence rate was in mothers aged≥35 years(22.2/10,000 LB).There were 12,271 specific congenital heart defects among 10,594 patients(1.16 CHD/patient).Atrial septal defect has the highest number of cases(3835),with a prevalence of 4.49/10,000 LB,corresponding to 31.3%of all *** CHD had an increasing prevalence trend in recent years,being highest in S?o Paulo City and≥35-year mothers.

关键词： Congenital abnormalities Epidemiology Heart defects Interrupted time series PrevalencePublic health

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Venous thrombosis and prothrombotic factors in inflammatory bowel disease

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World Journal of Gastroenterology 2014年第17期20卷 4857-4872页

作者： Fernando Magro Jo?o-Bruno soares Dália fernandes Gastroenterology Department of Centro Hospitalar S?o Jo?o 4200-319 PortoPortugal Institute of Pharmacology and Therapeutics Faculty of MedicineUniversity of Porto4200-319 PortoPortugal IBMC Institute for Molecular and Cell BiologyUniversity of Porto4150-180 PortoPortugal Gastroenterology Department of Hospital de Braga 4710-243 BragaPortugal Gastroenterology Department of Centro Hospitalar da Cova da Beira 6200-251 Covilh?Portugal

Patients with inflammatory bowel disease (IBD) may have an increased risk of venous thrombosis (VTE). PubMed, ISI Web of Knowledge and Scopus were searched to identify studies investigating the risk of VTE and the prevalence of acquired and genetic VTE risk factors and prothrombotic abnormalities in IBD. Overall, IBD patients have a two- to fourfold increased risk of VTE compared with healthy controls, with an overall incidence rate of 1%-8%. The majority of studies did not show significant differences in the risk of VTE between Crohn’s disease and ulcerative colitis. Several acquired factors are responsible for the increased risk of VTE in IBD: inflammatory activity, hospitalisation, surgery, pregnancy, disease phenotype (e.g., fistulising disease, colonic involvement and extensive involvement) and drug therapy (mainly steroids). There is also convincing evidence from basic science and from clinical and epidemiological studies that IBD is associated with several prothrombotic abnormalities, including initiation of the coagulation system, downregulation of natural anticoagulant mechanisms, impairment of fibrinolysis, increased platelet count and reactivity and dysfunction of the endothelium. Classical genetic alterations are not generally found more often in IBD patients than in non-IBD patients, suggesting that genetics does not explain the greater risk of VTE in these patients. IBD VTE may have clinical specificities, namely an earlier first episode of VTE in life, high recurrence rate, decreased efficacy of some drugs in preventing further episodes and poor prognosis. Clinicians should be aware of these risks, and adequate prophylactic actions should be taken in patients who have disease activity, are hospitalised, are submitted to surgery or are undergoing treatment.

关键词： Acquired Genetic Prothrombotic Venous thrombosis Risk of venous thrombosis Inflammatory bowel disease

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Acromyrmex ameliae sp. n. （Hymenoptera： Formicidae）： A new social parasite of leaf-cutting ants in Brazil

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Insect Science 2007年第3期14卷 251-257页

作者： DANIVAL JOSE DE SOUZA ILKA MARIA fernandes soares TEREZINHA MARIA CASTRO DELLA LUCIA Institut de Recherche sur la Biologie de 1'Insecte Université Francois Rabelais Tours France Departamento de Biologia Animal Laboratório de Ecologia de Comunidades Departamento de Biologia Geral Universidade Federal de Vicosa MG 36570-000 Brazil

The fungus-growing ants （Tribe Attini） are a New World group of〉 200 species, all obligate symbionts with a fungus they use for food. Four attine taxa are known to be social parasites of other attines. Acromyrmex （ Pseudoatta） argentina argentina and Acromyrmex （Pseudoatta） argentina platensis （parasites of Acromyrmex lundi）, and Acromyrmex sp. （a parasite of Acromyrmex rugosus） produce no worker caste. In contrast, the recently discovered Acromyrmex insinuator （a parasite of Acromyrmex echinatior） does produce workers. Here, we describe a new species, Acromyrmex ameliae, a social parasite of Acromyrmex subterraneus subterraneus and Acromyrmex subterraneus brunneus in Minas Gerais, Brasil. Like A. insinuator, it produces workers and appears to be closely related to its hosts. Similar social parasites may be fairly common in the fungus-growing ants, but overlooked due to the close resemblance between parasite and host workers.

关键词： Acromyrmex leaf-cutting ants social evolution social parasitism

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Histological Assessment of Bone Regeneration in the Maxilla with Homologous Bone Graft:A Feasible Option for Maxillary Bone Reconstruction

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Journal of Renewable Materials 2024年第1期12卷 131-148页

作者： Sergio Henrique Gonçalves Motta Ana Paula Ramos soares Juliana Campos Hasse fernandes Gustavo Vicentis Oliveira fernandes Graduate Center of Faculdade Redentor CLIVORio de JaneiroBrazil Periodontics and Oral Medicine Department University of Michigan School of DentistryAnn ArborMI48109USA Centre for Interdisciplinary Research in Health(CIIS) Universidade Católica PortuguesaViseu3504-505Portugal

Bone biomaterials have been increasingly used to reconstruct maxillary atrophic ***,the aim of this study was to evaluate bone reconstruction in the maxilla using a homologous cortico-cancellous FFB(lyophilized)graft and verify its *** individuals were included from 2014 to *** first surgery was performed to install homologous bone blocks in the *** period of the second intervention varied between 5 months and 15 days to 11 months(≈7.93 months).The biopsies were taken from the central region of the matured graft during the surgery for implant *** patients presented clinical and radiographic conditions for the installation of dental *** was a 100%of survival *** histological assessment showed that the homologous block bone graft was an osteoconductive biomaterial,with connective tissue present,and newly formed bone juxtaposed on its *** were bone trabeculae with osteocytes and active osteoblasts with connective tissue in the mineralization process;the remodeling process can be found through the reverse lines.A limited focus of necrosis with fibrosis was detected,with small resorption and areas of inflammatory infiltrate,but without clinical *** homologous block bone graft can be considered a feasible option to substitute the autogenous bone graft(gold standard),with predictable clinical and favorable histological *** patients had a shorter surgical period,low morbidity,and an unlimited amount of biomaterial available at an accessible cost.

关键词： Regeneration bone graft histology homologous allogenous autogenous

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Predicting the potential of sludge dewatering liquors to recover nutrients as struvite biominerals

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Environmental Science and Ecotechnology 2020年第3期3卷 50-59页

作者： Francisco Simoes Robert Colston Catarina Rosa-fernandes Peter Vale Tom Stephenson Ana soares Cranfield Water Science Institute Cranfield UniversityCranfieldMK430ALUK Technology and Development Severn Trent Water LtdAvon HouseSt.Martins RoadCoventryCV36PRUK

Phosphorus and nutrient recovery from wastewater as mineral salts can support local replenishment of fertilisers and reduce mining,contributing to the circular *** and related streams are rich in nutrients,however;there is need to develop bio-based processes to recover *** study investigates the fractions of phosphorus(P)used by Brevibacterium antiquum to form struvite biominerals(bio-struvite)in wastewater sludge dewatering *** 72h of incubation,25.6 mg P/L were recovered as bio-struvite from 12.4 mg P/L organic plus condensed P and 13.2 mg P/L of *** potential of sludge dewatering liquors to recover nutrients as struvite was investigated by characterising ten types of sludge liquors(originating from primary,secondary sludge,feed to anaerobic digester and digestate,from 3 types of wastewater treatment plants)for their P fractions together with other parameters relevant for *** *** indicated that liquors obtained from primary sludge,feed to anaerobic digesters and digestate were the most suitable to produce biostruvite,as these were found to frequently have a high content of organic and condensed P,between to 276-732 mg P/***,from all the investigated sites,presented a higher potential for bio-struvite production than with conventional struvite *** study demonstrated that *** could convert organic and condensed P into bio-struvite,and this opens up a completely new way to recover forms of phosphorus that are not typically available for nutrient recovery in a single process.

关键词： Biomineralization Centrate Sidestream P-recovery Acid-hydrolysable phosphorus

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Nutritional supplements use in high-performance athletes is related with lower nutritional inadequacy from food

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Journal of Sport and Health Science 2016年第3期5卷 368-374页

作者： Mónica Sousa Maria J.fernandes Pedro Carvalho José soares Pedro Moreira Vitor Hugo Teixeira Centre of Research Education Innovation and Intervention in Sport Faculty of Sport University of Porto Faculty of Nutrition and Food Sciences University of Porto Research Centre on Physical Activity Health and Leisure Faculty of Sport University of Porto

Background: The use of nutritional supplements(NS) among athletes is widespread. However, little is known about the relationship between nutritional adequacy and NS usage. The aims of this study were to evaluate the NS usage and to compare the nutritional intake from food and prevalence of micronutrient inadequacy(PMI) between NS users and ***: Portuguese athletes from 13 sports completed an NS usage questionnaire and a semi-quantitative food-frequency questionnaire assessing information over the previous 12 months. The estimated average requirement cut-point method was used to calculate PMI. General linear models were used to compare nutritional intake and NS usage. Chi-squared tests and logistic regression were performed to study, respectively,relationships and associations between PMI and NS ***: From the 244 athletes(66% males, 13–37 years), 64% reported NS usage. After adjustment, NS users showed a higher intake from food(p < 0.05), for at least 1 gender, for energy, and for 7 of the 17 studied nutrients. The highest PMI were seen for vitamins D and E, calcium, folate,and magnesium. After adjustment, NS users, irrespective of gender, reported lower PMI for calcium(OR = 0.28, 95%CI: 0.12–0.65), and female users for magnesium(OR = 0.06, 95%CI: 0.00–0.98).Conclusion: Athletes using NS reported a higher nutritional intake from food, and a lower PMI for several nutrients. Perhaps, those who were taking NS were probably the ones who would least benefit from it.

关键词： Carbohydrates Minerals Proteins Sport Vitamins

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Direct Electrochemical Determination of Glyphosate Herbicide Using a Screen-Printed Carbon Electrode Modified with Carbon Black and Niobium Nanoparticles

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Journal of Analysis and Testing 2023年第4期7卷 425-434页

作者： Julia Oliveira fernandes Cassiano Augusto Rolim Bernardino Juliana dos Santos fernandes Claudio Fernando Mahler Bernardo Ferreira Braz Luiz Henrique Carpenter dos Santos Rodrigo JoséCorrêa Ricardo Erthal Santelli Braulio soares Archanjo Emerson Schwingel Ribeiro Fernando Henrique Cincotto Departament of Analytical Chemistry Institute of ChemistryFederal University of Rio de JaneiroRio de Janeiro 21941-909Brazil Departament of Civil Engineering COPPEFederal University of Rio de JaneiroRio de Janeiro 21941-598Brazil National Institute of Science&Technology of Bioanalytics(INCTBio) CampinasSão Paulo 13083-862Brazil Departament of Inorganic Chemistry Institute of ChemistryFederal University of Rio de JaneiroRio de Janeiro 21941-909Brazil Unesp National Institute of Alternative Technologies for DetectionToxicological Assessment and Removal of Micropollutants and Radioactives(INCT-DATREM)AraraquaraSão Paulo 14800-060Brazil National Institute of Metrology Quality and TechnologyInmetroAv.Nossa Senhora das Graças50XerémDuque de Caxias 25250-020Brazil

Glyphosate is a herbicide that has been widely used worldwide and is used in agricultural areas to control weeds and unwanted *** sensors developed from different nanomaterials have high efficiency,excellent cost-benefit,and fast analysis time for detecting traces of environmental *** study aimed to produce an electrochemical sensor with disposable screen-printed electrodes based on carbon black modified with niobium nanoparticles to determine glyphosate in aqueous *** morphology,structure and electrochemical performance of the sensor were characterized by scanning electron microscopy,energy-dispersive X-ray spectroscopy,X-ray diffraction and cyclic *** pulse voltammetry in BR buffer solution at pH 5.0 allowed the generation of a method to quantify glyphosate concentration in a linear range of 5.90-172.30μmol/L(1.00-29.13μg/mL),with a limit of detection calculated at 3.07μmol/L(0.52μg/mL).The method efficiently quantified glyphosate in real water samples and showed no interference from K^(+),Na^(+),Ca^(2+),Mg^(2+)ions or thiamethoxam,imidacloprid and carbendazim pesticides.

关键词： Glyphosate Electrochemical sensor Carbon black Niobium nanoparticles

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微波等离子体化学气相沉积法在硅片上同时生长碳化硅和金刚石

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新型炭材料 2008年第3期23卷 250-258页

作者：唐春玖符连社 A.J.S.fernandes M.J.soares Gil Cabral A.J.Neves J.Grácio Center for Mechanical Technology and Automation and Department of Mechanical Engineering University of Aveiro Department of Physics and CICECO University of Aveiro Department of Physics University of Aveiro

研究了衬底温度、核化密度、衬底表面预处理等工艺参数对微波等离子体化学气相沉积法在硅片上同时生长碳化硅和金刚石的影响。采用扫描电镜、X-射线衍射、喇曼光谱和红外光谱对样品进行了表征。结果表明:从高核化密度生长的金刚石膜中... 详细信息

研究了衬底温度、核化密度、衬底表面预处理等工艺参数对微波等离子体化学气相沉积法在硅片上同时生长碳化硅和金刚石的影响。采用扫描电镜、X-射线衍射、喇曼光谱和红外光谱对样品进行了表征。结果表明:从高核化密度生长的金刚石膜中探测不到碳化硅;不论对硅衬底进行抛光预处理还是未抛光预处理,从低核化密度生长的金刚石厚膜中总能探测到碳化硅。碳化硅生长在硅衬底上未被金刚石覆盖的地方,或者是在金刚石晶核之间的空洞处。碳化硅形成和金刚石生长是同时发生的两个竞争过程。此研究结果为制备金刚石和碳化硅复合材料提供了一种新的方法。

关键词：碳化硅金刚石厚膜红外光谱微波等离子体气相化学沉积

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Tolerance to Salinity of Sesame Genotypes in Different Phenological Stages

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American Journal of Plant Sciences 2017年第8期8卷 1904-1920页

作者： Janivan fernandes Suassuna Pedro Dantas fernandes Marcos Eric Barbosa Brito Nair Helena Castro Arriel Alberto soares de Melo Josely Dantas fernandes Department of Biology State University of Paraiba UEPB Campina Grande Brazil Department of Agricultural Engineering Federal University of Campina Grande UFCG Campina Grande Brazil Department of Agricultural Science Federal University of Campina Grande UFCG Pombal Brazil Embrapa-Brazilian Agricultural Research Corporation Campina Grande Brazil Department of Agrobiology and Agriculture State University of Paraiba UEPB Lagoa Seca Brazil

The sesame crop is usually avoided in salt-affected areas because of the various effects of saline stress on plants. Besides varying between species, salinity effects are known to vary for genotypes of the same species as well as plant development stages. Thus, through the irrigation of plants with saline water, this study evaluates tolerance to saline stress of new sesame genotypes in different phenological stages. Three experiments were carried out under greenhouse conditions, using the sesame genotypes BRS Seda, LAG-927561 and LAG-26514. Water with different levels of electrical conductivity (ECw = 0.6, 1.6, 2.6, 3.6 and 4.6 dS m-1) was used to irrigate plants during germination and initial growth stages, as well as the entire crop cycle. Tolerance to saline stress (3.6 dS m-1) during growth and production stages was also studied. Salinity did not affect sesame germination, but seedling growth was hindered from the ECw of 1.6 dS m-1 onwards, and plant height was the most affected growth variable. Seed production is affected by salinity, regardless of the phenological stage in which plants are exposed to salinity. The strains LAG-927561 and LAG-26514 show promising signs in studies on adaptation to saline stress.

关键词： Sesamum indicum Development Stages Saline Stress Relative Crop Yield

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Total segmental aplasia of uterus body in bitch

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Asian pacific Journal of Reproduction 2019年第1期8卷 43-44页

作者： Leonardo Martins Leal Fábio Rodrigo Castro Bastos Tais Harumi de Castro Sasahara paola Castro Moraes Márcia Rita fernandes Machado Centro Universitário Ingá-UNINGá MaringáPRBrazil Universidade de Sao Paulo-USP Sao PauloSPBrazil Universidade Estadual Paulista-Unesp JaboticabalSPBrazil

Congenital anomalies of the female tubular genital tract are rare and known as segmental aplasia, resulting from incomplete development of paramesonephric ducts during embryonic stage, which originate from the cranial portion of vagina, cervix, uterus and oviducts. In the literature consulted, several reports of uterine horn aplasia are described in bitches, however there is only one report described in the world literature on total aplasia of the body of the uterus. This study aimed to describe the case of a two years old bitch, no breed defined, with 12 kg of weight, with segmental aplasia of uterus body diagnosed during ovariohysterectomy. During surgery it was noted that the bitch had the ovaries and uterine horns in their anatomical position, however an aplasia was noted in the body of the uterus. It was also found that the uterine horns had liquid inside, suggesting hydrometra. It was concluded in this case that although segmental aplasia of the body of the uterus is rare and difficult to diagnose by maintaining normal cyclicity of the female, it should be considered in dogs that do not have bloody vaginal discharge in proestrus and can not become pregnant after natural coverage or artificial insemination.

关键词： Segmental aplasia Surgery Ovariohysterectomy Reproduction

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