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国外医学（放射医学核医学分册） 1991年第5期15卷 205-206页

作者： Drexler G panzer w 戴光复

个人剂量的常规监测和现场的常规测量结果表明,职业性的全身剂量一般是很低的,而局部体剂量特别是手部和手指剂量可能达到剂量限值.因此,需要对局部体剂量进行监测.

关键词： X线诊断职业照射剂量监测

A tissue-engineered rostral migratory stream for directed neuronal replacement

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Neural Regeneration Research 2018年第8期13卷 1327-1331页

作者： John C.O'Donnell Kritika S.Katiyar Kate V.panzer D.Kacy Cullen Center for Brain Injury & Repair Department of Neurosurgery Perelman School of Medicine University of Pennsylvania Center for Neurotrauma Neurodegeneration & Restoration Corporal Michael Crescenz Veterans Affairs Medical Center School of Biomedical Engineering Drexel University Department of Bioengineering School of Engineering and Applied Science University of Pennsylvania

New neurons are integrated into the circuitry of the olfactory bulb throughout the lifespan in the mamma- lian brain--including in humans. These new neurons are born in the subventricular zone and subsequently mature as they are guided over long distances via the rostral migratory stream through mechanisms we are only just beginning to understand. Regeneration after brain injury is very limited, and although some neuroblasts from the rostral migratory stream will leave the path and migrate toward cortical lesion sites, this neuronal replacement is generally not sustained and therefore does not provide enough new neurons to alleviate functional deficits. Using newly discovered microtissue engineering techniques, we have built the first self-contained, implantable constructs that mimic the architecture and function of the rostral migratory stream. This engineered microtissue emulates the dense cord-like bundles of astrocytic somata and processes that are the hallmark anatomical feature of the glial tube. As such, our living microtissue-en- gineered rostral migratory stream can serve as an in vitro test bed for unlocking the secrets of neuroblast migration and maturation, and may potentially serve as a living transplantable construct derived from a patient＇s own cells that can redirect their own neuroblasts into lesion sites for sustained neuronal replace- ment following brain injury or neurodegenerative disease. In this paper, we summarize the development of fabrication methods for this microtissue-engineered rostral migratory stream and provide proof-of-princi- ple evidence that it promotes and directs migration of immature neurons.

关键词： rostral migratory stream glial tube astrocyte neuroblast brain injury neural repair neural regeneration tissue engineering

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《铁血三国志》华丽人物设定

中国电子与网络出版 2004年第Z1期 52-55页

作者： panzer

这款由华义自主研发的全3D线上游戏《铁血三国志》于今年初在北京China Joy展上获得不少好评,该游戏为北京华义2003年始研究开发的作品,开发至今约一年时间,过程中也有与欧美等国共同合作;另外在美术方面为了呈现“三国”的主题,也特别... 详细信息

这款由华义自主研发的全3D线上游戏《铁血三国志》于今年初在北京China Joy展上获得不少好评,该游戏为北京华义2003年始研究开发的作品,开发至今约一年时间,过程中也有与欧美等国共同合作;另外在美术方面为了呈现“三国”的主题,也特别邀请漫画家郑问操刀,画风充满华丽、夸张,极具创意性。这款作品预计在今年4月底会在大陆先进行封测,第三季后计划台湾、大陆同步上市。在当今的网游之中,传神的角色设定无疑是突出自己产品的重要手段之一。比如我们可以仅仅从几张图片、招贴上的人物就联想到该游戏的名称,《天堂Ⅱ》的美丽精灵、《魔力宝贝》的卡通小人……虽然现在《铁血三国志》还在开发之中,但借助郑问先生的笔触和开发人员的设定,《铁血三国志》的人物可谓越来越精细。今天,我们就先为大家介绍游戏中的“健壮女”(暂称,可能到游戏测试、发售后会有变动》角色。

关键词：三国志柳叶甲深衣

避孕套之国(连载二)——〔美〕Richard ***

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中国性科学 2000年第3期9卷 29-40页

作者： Richard A.panzer 国际教育基金会

第二部分观念战在避孕套之国进行我们已经见到,由于受那些持强烈的“性解放”观念同时又控制着大量的公共和私人基金的人们和集团的鼓动,美国的防止艾滋病政策已经被高度政治化了。许多这类基金会鼓吹带有欺骗、误导标记的未被证实的策... 详细信息

第二部分观念战在避孕套之国进行我们已经见到,由于受那些持强烈的“性解放”观念同时又控制着大量的公共和私人基金的人们和集团的鼓动,美国的防止艾滋病政策已经被高度政治化了。许多这类基金会鼓吹带有欺骗、误导标记的未被证实的策略。另一方面,读者依然保持着一种合理合法的期待:究竟用什么方法来防止艾滋病是有效的?总之,我们所谈论的是与孩子们的生命攸关的问题。

关键词：青少年性教育美国避孕套

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避孕套之国(连载三)

中国性科学 2000年第4期9卷 23-32页

作者： Richard A.panzer 国际教育基金会

十二、“避孕套之国”中的成年人的困惑我们中间不是有许多人想当然地认为“青年文化”是一种极具强势特点的文化吗?这种文化把几乎所有的青年人都描绘成性活跃的,他们为性激素所主宰,完全不能理解更积极的价值。1992年疾病控制中心的... 详细信息

十二、“避孕套之国”中的成年人的困惑我们中间不是有许多人想当然地认为“青年文化”是一种极具强势特点的文化吗?这种文化把几乎所有的青年人都描绘成性活跃的,他们为性激素所主宰,完全不能理解更积极的价值。1992年疾病控制中心的一项调查显示,全部高中生的46%(将近半数)的人没有婚前性关系。更新的一项调查显示,14—17岁的青少年中,有57%的人从未发生过性关系。即使是现在“节欲”被说成与“性活跃”

关键词：性行为风险性教育美国避孕套

Histopathological characteristics and causes of kidney graft failure in the current era of immunosuppression

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world Journal of Transplantation 2019年第6期9卷 123-133页

作者： Sandesh Parajuli Fahad Aziz Neetika Garg Sarah E panzer Emily Joachim Brenda Muth Maha Mohamed Justin Blazel weixiong Zhong Brad C Astor Didier A Mandelbrot Arjang Djamali Division of Nephrology Department of MedicineUniversity of WisconsinMadisonWI 53705United States Department of Pathology University of WisconsinMadisonWI 53705United States Department of Population Health Sciences University of WisconsinMadisonWI 53705United States Division of Transplantation Department of SurgeryUniversity of WisconsinMadisonWI 53705United States

BACKGROUND The histopathological findings on the failing kidney allograft in the modern era is not well studied. In this study, we present our experience working with kidney transplant recipients with graft failure within one year of the *** To report the histopathological characteristics of failed kidney allografts in the current era of immunosuppression based on the time after transplant, cause of the end-stage renal disease and induction immunosuppressive *** In a single-center observational study, we characterized the histopathological findings of allograft biopsies in kidney transplant recipients with graft failure within one year after the *** we identified 329 patients with graft failure that met the selection criteria between January 1, 2006 and December 31, 2016. The three most common biopsy findings were interstitial fibrosis and tubular atrophy(IFTA, 53%), acute rejection (AR, 43%) and transplant glomerulopathy(TG, 33%). Similarly, the three most common causes of graft failure based on the primary diagnosis were AR(40%),TG(17%), and IFTA(13%). Most grafts failed within two years of post-transplant(36%). Subsequently, approximately 10%-15% of grafts failed every two years: >2-4 years(16%), > 4-6 years(13%), > 6-8 years(11%), > 8-10 years(9%) and > 10 years(16%). AR was the most common cause of graft failure in the first six years(48%), whereas TG was the most prevalent cause of graft failure after 6 years(32%) of *** In the current era of immunosuppression, AR is still the most common cause of early graft failure, while TG is the most prevalent cause of late graft failure.

关键词： Kidney biopsy Acute rejection Graft failure Transplant glomerulopathy Interstitial fibrosis and tubular atrophy

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避孕套之国(连载四)

中国性科学 2001年第1期10卷 34-43页

作者： RichardA.panzer

十七、对一夫一妻制、婚姻的恐惧和颤抖闭口不谈一夫一妻制或婚姻(不仅象美国性信息与教育委员会(SIECUS)这样的组织如此,许多健康教育工作者也是如此),实际上是剥夺了学生的极其重要的讨论.我绝不会忘记,我在研究生院健康课程所谈到的... 详细信息

十七、对一夫一妻制、婚姻的恐惧和颤抖闭口不谈一夫一妻制或婚姻(不仅象美国性信息与教育委员会(SIECUS)这样的组织如此,许多健康教育工作者也是如此),实际上是剥夺了学生的极其重要的讨论.我绝不会忘记,我在研究生院健康课程所谈到的以节欲为中心的项目的有效性后,所举的例子之一是题为"自由青少年"的幻灯.

关键词：避孕套性进化论婚姻制度性行为性卫生

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避孕套之国(连载一)

中国性科学 2000年第2期9卷 29-43页

作者： Richard A.panzer 国际教育基金会

《避孕套之国:盲目的信仰,败坏的科学》(CONDOM NATION:Blind Faith,Bad Science)出版于1997年,作者理查德·潘哲毕业于耶鲁大学,他所开发的家庭生活教育项目在美国等40余个国家被采用,曾在美国、加拿大、英国、德国、法国、土耳其及日... 详细信息

《避孕套之国:盲目的信仰,败坏的科学》(CONDOM NATION:Blind Faith,Bad Science)出版于1997年,作者理查德·潘哲毕业于耶鲁大学,他所开发的家庭生活教育项目在美国等40余个国家被采用,曾在美国、加拿大、英国、德国、法国、土耳其及日本举办预防艾滋病和青少年性行为讲座。使用避孕套和“安全性行为”曾经是西方预防艾滋病性传播的最重要教育内容,然而推行避孕套产生的复杂社会影响却未引起各国政府的注意。美国政府曾大力支持避孕套教育,并对不同意见进行了排斥和压制,结果导致了一系列严重的消极后果。

关键词：青少年性教育美国避孕套

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随机对照试验评价氟康唑治疗儿科头癣的疗效

世界核心医学期刊文摘（皮肤病学分册） 2006年第2期2卷 8-9页

作者： Foster K.w. Friedlander S.F. panzer H. B.E. Elewski 冯义国 Department of Dermatology University of Alabama at Birmingham School of Medicine Eye Foundation Hospital 414 1720 University Boulevard Birmingham AL 35294- 0009United StatesDr.

Background: Griseofulvin is considered first- line therapy for tinea capitis, and the Physician’ s Desk Reference currently recommends 11 mg/kg per day microsize formulation for use in children. Diverse selective pressures have resulted in waning clinical efficacy of griseofulvin, such that higher doses and longer courses of treatment are required. These events have prompted the search for therapeutic alternatives. Fluconazole is one such treatment option, and a variety of studies using this drug have shown promise in the treatment of pediatric tinea capitis. Objective: we sought to assess the efficacy, safety, and optimal dose and duration of fluconazole therapy compared with standard- dose griseofulvin (11 mg/kg per day microsize formulation) in the treatment of pediatric tinea capitis. Methods: This randomized, multicenter, third- party- blind, 3- arm trial was designed as a superiority study to identify a therapeutically superior agent/regimen from the 3 treatment arms: (1) fluconazole 6 mg/kg per day for 3 weeks followed by 3 weeks of placebo, (2) fluconazole 6 mg/kg per day for 6 weeks, and (3) griseofulvin 11 mg/kg per day for 6 weeks. Efficacy variables included mycological, clinical, and combined outcomes. The primary efficacy variable was the combined outcome of the modified intent- to- treat population at week 6. Patient safety was assessed throughout the study. Statistical analysis of the efficacy variables was conducted by means of the Cochran- Mantel- Haenszel test. Results: At the end of treatment, mycological cures were present in 44.5% , 49.6% , and 52.2% of the fluconazole 3- week, fluconazole 6- week, and griseofulvin groups, respectively. Analysis of the primary efficacy variable failed to identify any superior agent, and differences between the combined outcomes of the fluconazole 6- week and griseofulvin groups at week 6 were not significant (P=.32). Regarding mycological, clinical, and combined outcomes, no significant differences between the

关键词：随机对照试验最佳剂量标准剂量真菌学主要疗效选择性压力试验研究安慰剂性接触盲法

使用MCS+两种不同血小板采集程序采集血小板的比较

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国外医学（输血及血液学分册） 2003年第5期26卷 474-475页

作者： G.Stiegler G.Leitner S.panzer P.Hcker 洪缨成都市血液中心

目前,用制备技术或通过过滤能降低单采血小板的白细胞。在单采时使用流体化粒子床技术,淘洗原理,或定期改变界面位置去除白细胞。另一方面,在单采后进行单采血小板的自细胞过滤。MCS+C版本运用后一原理,在管路上过滤(***,MA,USA)。在最... 详细信息

目前,用制备技术或通过过滤能降低单采血小板的白细胞。在单采时使用流体化粒子床技术,淘洗原理,或定期改变界面位置去除白细胞。另一方面,在单采后进行单采血小板的自细胞过滤。MCS+C版本运用后一原理,在管路上过滤(***,MA,USA)。在最近一项研究中,MCS+管路上过滤去除单采血小板中自细胞被证实比其它白细胞去除技术更好。但人们认为单采后过滤血小板会引起血小板损失。

关键词：血小板采集程序 MCS 白细胞过滤制备技术输血