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Wolbachia symbiosis and insect immune response

Computational Water, Energy, and Environmental Engineering（水能与环境工程） 2024年第1期

作者： George Bousbouras panagiotis Angelidis

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Insect Science 2008年第1期15卷 89-100页

作者： Stefanos Siozios panagiotis Sapountzis panagiotis Ioannidis Kostas Bourtzis Department of Environmental and Natural Resources Management University of Ioannina Agrinio 30100 Greece

Bacterial intraceUular symbiosis is very common in insects, having significant consequences in promoting the evolution of life and biodiversity. The bacterial group that has recently attracted particular attention is Wolbachia pipientis which probably represents the most ubiquitous endosymbiont on the planet. W. pipientis is a Gram-negative obligatory intracellular and maternally transmitted a-proteobacterium, that is able to establish symbiotic associations with arthropods and nematodes. In arthropods, Wolbachia pipientis infections have been described in Arachnida, in Isopoda and mainly in Insecta. They have been reported in almost all major insect orders including Diptera, Coleoptera, Hemiptera, Hymenoptera, Orthoptera and Lepidoptera. To enhance its transmission, W. pipientis can manipulate host reproduction by inducing parthenogenesis, feminization, male killing and cytoplasmic incompatibility. Several polymerase chain reaction surveys have indicated that up to 70% of all insect species may be infected with W. pipientis. How does W. pipientis manage to get established in diverse insect host species？ How is this intracellular bacterial symbiont species so successful in escaping the host immune response？ The present review presents recent advances and ongoing scientific efforts in the field. The current body of knowledge in the field is summarized, revelations from the available genomic information are presented and as yet unanswered questions are discussed in an attempt to present a comprehensive picture of the unique ability of W. pipientis to establish symbiosis and to manipulate reproduction while evading the host＇s immune system.

关键词： Drosophila immune response insects symbionts Wolbachia

Supporting decision-making processes for selecting fire safety measures for road tunnels

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Journal of Traffic and Transportation Engineering(English Edition) 2022年第3期9卷 473-489页

作者： panagiotis Ntzeremes Konstantinos Kirytopoulos School of Mechanical Engineering National Technical University of AthensAthens 10682Greece

Selecting fires safety measures for road tunnels relies mainly on strict regulatory requirements. However, the choice should also be based on many different criteria and ranking of alternatives should take place. Existing methods exhibit lack in dealing rigorously with measures’ selection amongst different alternatives. This paper contributes to the body of knowledge by proposing a novel method, named EVADE, which aims to incorporate diverse stakeholders’ views and provide a meaningful ranking of *** do so, it estimates the tunnel level of safety taking into account only any standard measures existing. Subsequently, the performance of additional measures is ***, a list of the most significant criteria that are valuable to judge the appropriateness of selected measures is introduced. The relative importance amongst the decision criteria is calculated through the Analytic Hierarchy Process, based on the expert opinion. Sensitivity analysis through Monte Carlo simulation is embedded to allow for a meaningful prioritization of the decision criteria. Thus, the alternatives’ ranking comes as a distribution instead of a single number, providing the decision-maker richer information for selecting the most suitable measure(s) according to the specific tunnel situation. At last, a typical tunnel is examined to showcase the utilization of the method.

关键词： Road tunnel Critical infrastructure Decision-making Quantitative-risk-assessment

Evaluating the role of risk assessment for road tunnel fire safety: A comparative review within the EU

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Journal of Traffic and Transportation Engineering(English Edition) 2019年第3期6卷 282-296页

作者： panagiotis Ntzeremes Konstantinos Kirytopoulos School of Mechanical Engineering National Technical University of Athens Athens 15780 Greece School of Natural and Built Environments University of South Australia Adelaide South Australia 5001 Australia

Fire is the foremost critical event for road tunnels’ safety. Therefore, the European Commission introduced the Directive 2004/54/EC for enhancing tunnels’ safety since they constitute a key element of the Trans-European Road Network. The Directive has established a common ground for tunnels’ safety evaluation providing certain minimum requirements while introducing officially the use of risk assessment. Despite the signifi-cant progress, this paper illustrates that further efforts are needed. Through a comparative review of the risk assessment methods, questions about the level of harmonisation of the framework are raised. Moreover, considerable problems are highlighted, like the incorporation of the new trends emerging from the literature or the deficiencies on addressing significant issues of the analysis, such as the risk acceptance criteria and the behaviour of trapped-users. These problems can affect the risk assessment process causing both significant discrepancies and deficiencies at the estimated level of tunnels’ ***, thus, the deficiencies and limitations of the methods, this paper contributes to i) the discourse for initiating relevant studies to enhance tunnels’ fire safety in Europe and worldwide, and ii) the harmonisation of risk assessment methods.

关键词： Road tunnel Safety Fire Risk assessment

Biogas and its opportunities——A review

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Frontiers of Environmental Science & Engineering 2018年第3期12卷 1-12页

作者： panagiotis G. Kougias Irini Angelidaki Department of Environmental Engineering Technical University of Denmark Kgs. Lyngby DK-2800 Denmark

Biogas production is a well-established technology primarily for the generation of renewable energy and also for the valorization of organic residues. Biogas is the end product of a biological mediated process, the so called anaerobic digestion, in which different microorganisms, follow diverse metabolic pathways to decompose the organic matter. The process has been known since ancient times and was widely applied at domestic households providing heat and power for hundreds of years. Nowadays, the biogas sector is rapidly growing and novel achievements create the foundation for constituting biogas plants as advanced bioenergy factories. In this context, the biogas plants are the basis of a circular economy concept targeting nutrients recycling, reduction of greenhouse gas emissions and biorefinery purposes. This review summarizes the current state-of-the-art and presents future perspectives related to the anaerobic digestion process for biogas production. Moreover, a historical retrospective of biogas sector from the early years of its development till its recent advancements gives an outlook of the opportunities that are opening up for process optimisation.

关键词： Anaerobic digestion Biogas Biowastes Solid waste Manure Industrial waste

Comparison of blood rheological models in patient specific cardiovascular system simulations

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Journal of Hydrodynamics 2017年第2期29卷 293-304页

作者： Anastasios Skiadopoulos panagiotis Neofytou Christos Housiadas Thermal Hydraulics and Multiphase Flows Laboratory I.N.RA.S.T.E.SN.C.S.R.

Newtonian, Quemada and Casson blood viscosity models are implemented in order to simulate the rheological behavior of blood under pulsating flow conditions in a patient specific iliac bifurcation. The influence of the applied blood constitutive equations is monitored via the wall shear stress （WSS） distribution, magnitude and oscillations, non-Newtonian importance factors, and viscosity values according to the shear rate. The distribution of WSS on the vascular wall follows a pattern which is independent of the theological model chosen. On the other hand, the WSS magnitude and oscillations are directly related to the blood constitutive equations applied and the shear rate. It is concluded that the Newtonian approximation is satisfactory only in high shear and flow rates. Moreover, the Newtonian model seems to overestimate the possibility for the formation of atherosclerotic lesions or aneurysms at sites of the vascular wall where the WSS are oscillating.

关键词： Key words: Blood flow simulation patient specific geometries geometry reconstruction non-Newtonian models wall shear stress,pulsating flow

Numerical analysis of slope collapse using SPH and the SIMSAND critical state model

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Journal of Rock Mechanics and Geotechnical Engineering 2022年第1期14卷 169-179页

作者： Zhao Lu Zhuang Jin panagiotis Kotronis Civil and Environmental Engineering University of MacaoMacaoChina Research and Development Center Shenzhen Foundation Engineering Co.Ltd.Shenzhen518000China Department of Civil and Environmental Engineering The Hong Kong Polytechnic UniversityHong KongChina Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou) Guangzhou510000China Department of Ocean Science and Engineering Southern University of Science and TechnologyShenzhen518000China Institut de Recherche en Génie Civil et Mécanique(GeM) École Centrale de NantesUniversitéde NantesRue de la NoëNantes44321France

Geological disasters such as slope failure and landslides can cause loss of life and ***,reproducing their evolution process is of great importance for risk assessment and *** recently developed SIMSAND critical state sand model combined with the smoothed particle hydrodynamics(SPH)method is adopted in this work to study slope failure under large *** illustrate the efficiency and accuracy of the SIMSAND-SPH approach,a series of slope collapse studies using the discrete element method(DEM)considering various particle shapes(***,tetrahedral and elongated)is adopted as *** parameters of the SIMSAND model are calibrated using DEM triaxial *** comparison to the DEM simulations,the runout distance and final slope height are well characterized with the SIMSAND-SPH approach with less computational *** comparisons show that the SIMSAND-SPH approach is highly efficient and accurate,which can be an alternative numerical tool to simulate real scale granular flow.

关键词： Granular material Smoothed particle hydrodynamics(SPH) Large deformations Landslide Critical state Slope failure Sand

Fluxes,stocks and availability of nitrogen in evergreen broadleaf and fir forests:similarities and differences

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Journal of Forestry Research 2021年第5期32卷 2059-2066页

作者： panagiotis Michopoulos Athanassios Bourletsikas Kostas Kaoukis o.demeter-institute of mediterranean forest ecosystems terma alkmanos11528 athensgreece

In this study,nitrogen fluxes or flows in litterfall,nitrogen stocks and available nitrogen in soils of two plots representing evergreen broadleaf and Bulgarian fir forests were *** plots are in good quality sites and for this reason,the litterfall quantities and nitrogen fluxes were relatively *** woody litterfall flux of nitrogen was significantly higher in the fir forest than in the evergreen broadleaf *** total nitrogen stock was higher in the soil under the fir ***,the percentage of the available nitrogen(ammonium+nitrates)was significantly higher in the upper 20 cm soil layer of the evergreen broadleaf forest in spite of the higher average C/N ratios in the foliar litterfall of the broadleaf forest and insignificant difference of the C/N ratios in all soil layers of the two *** microclimatic conditions(higher soil temperatures in the evergreen broadleaf forest)is probable possible cause for this *** available nitrogen in the soils and its retranslocation from senescing leaves cover the nitrogen requirements of *** is hypothesized that trees may also take up nitrogen from deeper soil layers.

关键词： Maquis Fir Nitrogen Litterfall fluxes Soil

Automation of input data to discrete event simulation for manufacturing: A review

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International Journal of Modeling, Simulation, and Scientific Computing 2016年第1期7卷 93-119页

作者： panagiotis Barlas Cathal Heavey Enterprise Research Centre University of Limerick LimerickIreland

Discrete event simulation(DES)is a well-established decision support tool in modeling work flows in manufacturing ***,there are an amount of practical and financial obstacles that deter the employment of this technology in *** of the main weaknesses of operating DES is the costs spent on collecting and mapping input data from different enterprise data resources into a DES *** issue is the cost of integrating simulation applications with other manufacturing *** barriers hinder the automated input of data into DES models and as a result deter use of real-time DES in *** review presents the existing research studies in the literature that address the above issues,demonstrating in parallel the already implemented *** scope of this review is to provide an overview of the input data phase,focusing on its automation and motivating researchers to re-examine this phase by highlighting future research directions.

关键词： Discrete event simulation input data automation

i4sea:a big data platform for sea area monitoring and analysis of fishing vessels activity

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Geo-Spatial Information Science 2022年第2期25卷 132-154页

作者： panagiotis Tampakis Eva Chondrodima Andreas Tritsarolis Aggelos Pikrakis Yannis Theodoridis Kostis Pristouris Harry Nakos panagiotis Kalampokis Theodore Dalamagas Data Science Lab University of PiraeusPiraeusGreece Institute of Mathematics and Computer Science University of Southern DenmarkOdenseDenmark ATHENA Research Center Information Management Systems InstituteMarousiGreece

The i4sea research project provides effective and efficient big data integration,processing,and analysis technologies to deliver both real-time and historical operational snapshots of fishing vessels activity in national sea *** paper presents the architecture of the i4sea big data platform for sea area monitoring and analysis of fishing vessels activity and demonstrates the operation of some use-case pilot scenarios.

关键词： Big data fishing vessel activity machine learning