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Sterilization Efficacy of Demolizer Technology for Onsite Treatment of Sharps and Other Regulated Medical Waste against Staphylococcus aureus, Escherichia coli, Candida albicans,Mycobacterium phleiand Bacillus subtilisSpores

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Open Journal of Medical Microbiology 2012年第3期2卷 77-83页

作者： James Marsden Jasdeep Saini Maria Teresa Ortega Diane Gorder pamela hatesohl Department of Animal Science and Industry Kansas State University Manhattan USA

This study was performed to evaluate the efficacy of the Demolizer? technology for the on-site sterilization of low vo-lumes of regulated medical waste. The objective was to demonstrate a minimum of 6 log10 reduction of the dry heat sterilization process applied by the Demolizer? II system for the representative organisms, Staphylococcus aureus, Escherichia coli, Candida albicans, Mycobacterium phlei and Bacillus subtilis spores (formerly Bacillus subtilis) on simulated medical waste consistent with numerous regulatory standards for medical waste treatment. The system cycle was heat treatment at a minimum temperature of 350?F and held at or above this temperature for a minimum of 90 minutes. Upon completion of treatment, there was no evidence of growth in the bacterial species after treatment. Given the minimum detection level of 4 CFU/ml, the Demolizer? II system demonstrated a minimum sterilization efficacy of 6.6 log10 for both S. aureus and E. coli as representative gram-positive and gram-negative bacteria species. Candida albicans (6.7 log10 CFU/ml), Mycobacterium phlei (9.0 log10 CFU/ml) and Bacillus subtilis (6.3 log10 CFU/ml) were completely eliminated after sterilizing representative medical waste in the Demolizer? II system for 90 minutes at a minimum temperature of 350?F. Also, the Demolizer? II exceeded typical recognized standards for medical waste treatment of a 6 log10 reduction of Mycobacteria and a 4 log10 reduction of the appropriate Bacillus endospore.

关键词： Regulated Medical Waste Onsite Treatment Sharps Demolizer Technology

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Iron regulatory protein 1: the deadly switch of ferroptosis

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Neural Regeneration Research 2024年第3期19卷 477-478页

作者： Daniel A.Bórquez pamela J.Urrutia Center for Biomedical Research Faculty of MedicineUniversidad Diego PortalesSantiagoChile Institute of Nutrition&Food Technology(INTA) Universidad de ChileSantiagoChile Geroscience Center for Brain Health and Metabolism SantiagoChile

Ferroptosis,an iron-dependent cell death:Ferroptosis is a type of regulated necrosis,characterized by redox-active iron accumulation and increased free radical production derived by Fenton chemistry,that triggers oxidation of polyunsaturated fatty acids in phospholipids,loss of cellular membranes integrity,and leakage of intracellular contents.

关键词： integrity switch Iron

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Following the Threads

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Beijing Review 2024年第3期67卷 44-45页

作者： pamela Tobey 不详

China has a wide variety of items on its official intangible cultural heritage(ICH)list,and one of the most colorful folk crafts included is the embroidery of the Yi ethnic *** a history stretching back 1,700 years,this art form has been handed down from mother to daughter and its designs reflect their close relationship with nature.

关键词： mother daughter stretching

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Pregnancy stressors and postpartum symptoms of depression and anxiety:the moderating role of a cognitivebehavioural therapy(CBT)intervention

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General Psychiatry 2024年第1期37卷 112-121页

作者： Yunxiang Sun Soim Park Abid Malik Najia Atif Ahmed Zaidi Atif Rahman pamela J Surkan Department of International Health Johns Hopkins University Bloomberg School of Public HealthBaltimoreMarylandUSA Department of Public Mental Health Health Services AcademyIslamabadPakistan Human Development Research Foundation RawalpindiPakistan Department of Primary Care and Mental Health Institute of Population HealthUniversity of LiverpoolLiverpoolUK

Background Little is known about the association between stressors(especially positive stressors)during pregnancy and postpartum depression and *** We investigated the association between positive and negative stress events during different stages of pregnancy and postpartum mental health outcomes among low-income pregnant women with symptoms of anxiety in Pakistan and evaluated whether an intervention based on cognitive behavioural therapy(CBT)had a regulatory *** Participants were 621 pregnant Pakistani women with mild *** the Pregnancy Experience Scale-Brief Version,six scores were created to assess positive and negative *** performed a multivariate linear regression to examine whether these six scores,measured both at baseline and in the third trimester,were associated with postpartum anxiety and depressive *** effect of the intervention on this relationship was examined by adding an interaction term to the regression *** Hassles frequency measured in the third trimester was positively associated with depression(B=0.22,95%confidence interval(Cl):0.09 to 0.36)and anxiety(B=0.19,95%Cl:0.08to 0.30).At the same timepoint,uplifts intensity was negatively associated with symptoms of depression(B=-0.82,95%Cl:1.46 to-0.18)and anxiety(B=-0.70,95%Cl:-1.25 to-0.15),whereas hassles intensity was positively related to symptoms of depression(B=1.02,95%Cl:0.36 to 1.67)and anxiety(B=0.90,95%Cl:0.34 to 1.47).The intensity ratio of hassles to uplifts reported in the third trimester was positively related to both depression(B=1.40,95%Cl:0.59 to 2.20)and anxiety(B=1.26,95%Cl:0.57 to 1.96).The intervention strengthened the overall positive effects of uplfts and the negative effects of *** experiences at baseline during early pregnancy to mid-pregnancy were not associated with mental health *** Stressors in the third trimester but not earlier in pregnancy were associated with postpartum symptoms

关键词： postpartum stress behaviour

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Fashion on the Stage

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Beijing Review 2024年第3期67卷 46-47页

作者： pamela Tobey(Text/photos) 不详

The inaugural China Chuxiong Fashion Week was held in the Chuxiong Yi Autonomous Prefecture,Yunnan Province,from December 30,2023 to January *** event showcased the creativity of fashion through nearly 40 runway shows over the week and included participants from around China and from Laos,Cambodia,Thailand,Viet Nam,Myanmar,Malaysia and Bangladesh.

关键词： Malaysia Thailand Myanmar

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Sharing Song

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小学生时代（大嘴英语） 2024年第9期 18-21页

作者： pamela Love Laura Montenegro(图) 不详

Sing a song of sharing Apples in a tree:Some for squirrels,and some for birds,And some of them for me.

关键词： some birds Apple

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Impacts of brood parasitism by shiny cowbird Molothrus bonariensis on the breeding success of a small host, the black-backed water tyrant Fluvicola albiventer

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Current Zoology 2024年第4期70卷 539-547页

作者： Lorena Vanesa Sovrano Evelina Jesica Leon Rodrigo Ezequiel Lorenzón pamela Fernanda Olguin Adolfo Héctor Beltzer Alejandro Raúl Giraudo Laboratorio de Biodiversidad y Conservacion de Tetrapodos Instituto Nacional de Limnologia(INALICONICET-UNL)Paraje El Pozo s/nSanta Fe(3000)Argentina Departamento de Biologia Universidad Autonoma de Entre RiosKm 10.5 RP 11Oro Verde(3100)Entre RiosArgentina Departamento de Biologia Universidad Nacional del LitoralFacultad de Humanidades y CienciasParaje Ei Pozo s/nSanta Fe(3000)Argentina

The shiny cowbird Molothrus bonariensis parasitizes many species with different life-history traits and has a detrimental effect on the survival of the progeny of the *** response,hosts have developed numerous antiparasitic ***,we examined the effects of brood parasitism by shiny cowbird on the clutch and brood sizes(83 nests)in a small host,the black-backed water tyrant Fluvicola *** also studied whether the death of parasite nestlings was related to the care of the foster parents and whether the host had any antiparasitic defense against the shiny *** results indicate that brood parasitism significantly decreased the host hatching and fledging *** majority of nest failures(57%)were caused by brood *** cowbird parasitism occurred in 52%of nests and the intensity of parasitism was 1.23±0.53 eggs per parasitized *** the total host eggs,54%were *** the incubation stage,20 nests(47%)were abandoned because of egg punctures by shiny cowbirds *** two parasitic fledglings were recorded,while the remaining nestlings either died from starvation(n=12)or predation(n=3).Foster parents abandoned parasitic nestlings between 5 and 10 days *** findings demonstrate that the shiny cowbird has very low rates of fledging success when parasitizing black-backed water ***,parasitism had a high reproductive cost in the black-backed water tyrant because a very low proportion(7%)of the parasitized nests(n=43)were successful.

关键词： brood parasitism host defenses nest desertion shiny cowbird small host.

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Effect of resistance training volume on body adiposity,metabolic risk,and inflammation in postmenopausal and older females:Systematic review and meta-analysis of randomized controlled trials

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Journal of Sport and Health Science 2024年第2期13卷 145-159页

作者： Paulo Ricardo Prado Nunes pamela Castro-e-Souza Anselmo Alves de Oliveira Bruno de Freitas Camilo Gislaine Cristina-Souza Lucio Marques Vieira-Souza Marcelo Augusto da Silva Carneiro Department of Body and Human Movement Minas Gerais State University(UEMG)37902-092 PassosMGBrazil University Center of Planalto de Araxa(UNIARAXA) 38180-129 AraxaMGBrazil Physical Activity Health and Ageing Research Group(GPASE)Minas Gerais State University(UEMG)37902-092 PassosMGBrazil Exercise and Nutrition Research Group(GPEN) Minas Gerais State University(UEMG)37902-092 PassosMGBrazil Sport Sciences and Physical Exercise Study and Research Group(GEPCEEX) Minas Gerais State University(UEMG)37902-092 PassosMGBrazil Metabolism Nutrition and Exercise LaboratoryPhysical Education and Sport CenterLondrina State University(UEL)86050-070 LondrinaPRBrazil Postgraduate Program in Physical Education Federal University of Sergipe(UFS)49107-230 Sao CristovaoSEBrazil

Purpose:This meta-analytical study aimed to explore the effects of resistance training(RT) volume on body adiposity,metabolic risk,and inflammation in postmenopausal and older ***:A systematic search was performed for randomized controlled trials in PubMed,Scopus,Web of Science,and *** controlled trials with postmenopausal and older females that compared RT effects on body adiposity,metabolic risk,and inflammation with a control group(CG) were *** reviewers selected the studies,extracted the data,and performed the risk of bias and certainty of the evidence(Grading of Recommendations,Assessment,Development,and Evaluation(GRADE)) *** body and abdominal adiposity,blood lipids,glucose,and C-reactive protein were included for meta-analysis.A random-effects model,standardized mean difference(Hedges’ g),and 95% confidence interval(95%CI) were used for ***:Twenty randomized controlled trials(overall risk of bias:some concerns;GRADE:low to very low) with overweight/obese postmenopausal and older females were *** groups were divided into low-volume RT(LVRT,~44 sets/week) and high-volume RT(HVRT,~77 sets/week).Both RT groups presented improved body adiposity,metabolic risk,and inflammation when compared to ***,HVRT demonstrated higher effect sizes than LVRT for glucose(HVRT=-1.19;95%CI:-1.63 to-0.74;LVRT=-0.78;95%CI:-1.15 to-0.41) and C-reactive protein(HVRT=-1.00;95%CI:-1.32 to-0.67;LVRT=-0.34;95%CI,-0.63 to-0.04)) when compared to ***:Compared to CG,HVRT protocols elicit greater improvements in metabolic risk and inflammation outcomes than LVRT in overweight/obese postmenopausal and older females.

关键词： C-reactive protein Fat mass Lipid profile Menopause Strength training

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Modeling the Drying Kinetics of Pigeon Pea [Cajanus cajan (L.) Millspaugh]

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Open Journal of Applied Sciences 2024年第6期14卷 1425-1436页

作者： Nadia pamela Gladys Pambou-Tobi Arnaud Wenceslas Geoffroy Tamba Sompila Michel Elenga Reyes Herdenn Gampoula Gloire Horiane Louya Banzouzi Sylvia Petronille Ntsossani National Institute for Research in Engineering Sciences Innovation and Technology Brazzaville Congo National Polytechnic School Marien Ngouabi University Brazzaville Congo Pole of Excellence in Food and Nutrition Faculty of Science and Technology Marien Ngouabi University Brazzaville Congo

We set out to model the oven-drying kinetics of a legume known as pigeon pea, harvested in the Bouenza department in the south-west of the Republic of Congo. The drying kinetics of pigeon peas was carried out in an oven under experimental conditions using temperatures of: 50°C, 60°C and 70°C. Seven mathematical models were used to describe pigeon pea drying. During drying, water loss was faster and shorter at 70°C [10.446 g/25 g wet weight (wwb) for 320 min (5.3 h)] compared to 50°C [10.996 g/25 g wet weight (wwb) for 520 min (8.6 h)] and 60°C [10.616 g/25 g wet weight (wwb) for 420 min (7.0 h)] where it was slower and longer. With regard to modeling, and based on the principle of choosing the right model focusing on the high value of R2 and low values of χ2 and RMSE, two models were selected, the Midili model for temperatures of 50°C and 60°C and the Henderson and Pabis model modified for temperature of 70°C showed better results. The R2, χ2 and RMSE values calculated for pigeon pea are 0.99985, 3.93404E-5 and 0.00627;0.9997, 9.245E-5 and 0.00962;0.99996, 1.56332E-5 and 0.00395 respectively at 50°C, 60°C and 70°C.

关键词： Cajanus cajan Legume Kinetic Models Drying

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Optimization of Stealthwatch Network Security System for the Detection and Mitigation of Distributed Denial of Service (DDoS) Attack: Application to Smart Grid System

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Communications and Network 2024年第3期16卷 108-134页

作者： Emmanuel S. Kolawole Penrose S. Cofie John H. Fuller Cajetan M. Akujuobi Emmanuel A. Dada Justin F. Foreman pamela H. Obiomon Electrical and Computer Engineering Department Prairie View A&M University Prairie View TX USA

The Smart Grid is an enhancement of the traditional grid system and employs new technologies and sophisticated communication techniques for electrical power transmission and distribution. The Smart Grid’s communication network shares information about status of its several integrated IEDs (Intelligent Electronic Devices). However, the IEDs connected throughout the Smart Grid, open opportunities for attackers to interfere with the communications and utilities resources or take clients’ private data. This development has introduced new cyber-security challenges for the Smart Grid and is a very concerning issue because of emerging cyber-threats and security incidents that have occurred recently all over the world. The purpose of this research is to detect and mitigate Distributed Denial of Service [DDoS] with application to the Electrical Smart Grid System by deploying an optimized Stealthwatch Secure Network analytics tool. In this paper, the DDoS attack in the Smart Grid communication networks was modeled using Stealthwatch tool. The simulated network consisted of Secure Network Analytic tools virtual machines (VMs), electrical Grid network communication topology, attackers and Target VMs. Finally, the experiments and simulations were performed, and the research results showed that Stealthwatch analytic tool is very effective in detecting and mitigating DDoS attacks in the Smart Grid System without causing any blackout or shutdown of any internal systems as compared to other tools such as GNS3, NeSSi2, NISST Framework, OMNeT++, INET Framework, ReaSE, NS2, NS3, M5 Simulator, OPNET, PLC & TIA Portal management Software which do not have the capability to do so. Also, using Stealthwatch tool to create a security baseline for Smart Grid environment, contributes to risk mitigation and sound security hygiene.

关键词： Smart Grid System Distributed Denial of Service (DDoS) Attack Intrusion Detection and Prevention Systems Detection Mitigation and Stealthwatch

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