检索结果-南通市图书馆

Mirror-enhanced super-resolution microscopy

在线全文

学校读者我要写书评

暂无评论

Light(Science & Applications) 2016年第1期5卷 357-364页

作者： Xusan Yang Hao Xie eric Alonas Yujia Liu Xuanze Chen Philip j Santangelo Qiushi Ren Peng Xi Dayong jin Department of Biomedical Engineering College of EngineeringPeking UniversityNo.5 Yiheyuan RoadBeijing 100871China Wallace H Coulter Department of Biomedical Engineering Georgia Institute of Technology and Emory UniversityAtlantaGA 30332USA Advanced Cytometry Labs ARC Centre of Excellence for Nanoscale BioPhotonics(CNBP)Macquarie UniversitySydneyNSW 2109Australia Institute for Biomedical Materials and Devices(IBMD) Faculty of ScienceUniversity of Technology SydneySydneyNSW 2007Australia

Axial excitation confinement beyond the diffraction limit is crucial to the development of next-generation,super-resolution *** Emission Depletion(STED)nanoscopy offers lateral super-resolution using a donut-beam depletion,but its axial resolution is still over 500 *** internal reflection fluorescence microscopy is widely used for single-molecule localization,but its ability to detect molecules is limited to within the evanescent field of~100 nm from the cell attachment *** find here that the axial thickness of the point spread function(PSF)during confocal excitation can be easily improved to 110 nm by replacing the microscopy slide with a *** interference of the local electromagnetic field confined the confocal PSF to a 110-nm spot axially,which enables axial super-resolution with all laser-scanning *** sectioning can be obtained with wavelength modulation or by controlling the spacer between the mirror and the *** no additional complexity,the mirror-assisted excitation confinement enhanced the axial resolution six-fold and the lateral resolution two-fold for STED,which together achieved 19-nm resolution to resolve the inner rim of a nuclear pore complex and to discriminate the contents of 120 nm viral *** ability to increase the lateral resolution and decrease the thickness of an axial section using mirror-enhanced STED without increasing the laser power is of great importance for imaging biological specimens,which cannot tolerate high laser power.

关键词： confocal interference point spread function super-resolution

Fibre Distribution in Friction-spun Yarns

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

journal of Donghua University(English Edition) 2006年第2期23卷 92-95页

作者： eric Oyondi Nganyi 郁崇文 College of Textiles Donghua University

According to the yarn forming characteristics in friction spinning, the arrangement of fed sliver is designed, to get the desired fiber distribution in the resultant yarn. On the base of that, the relation between the... 详细信息

关键词： Friction-spun yarns fibre distribution FR conex blended yarns.

Heat and drought impact on carbon exchange in an age-sequence of temperate pine forests

在线全文

学校读者我要写书评

暂无评论

Ecological Processes 2022年第1期11卷 108-125页

作者： M.Altaf Arain Bing Xu jason j.Brodeur Myroslava Khomik Matthias Peichl eric Beamesderfer Natalia Restrepo‑Couple Robin Thorne School of Earth Environment and Society and McMaster Centre for Climate ChangeMcMaster University1280 Main Street WestHamiltonON L8S 4K1Canada Department of Biological Sciences University of CalgaryAlbertaCanada Department of Geography and Environmental Management University of WaterlooWaterlooONCanada Department of Forest Ecology and Management Swedish University of Agricultural SciencesUmeåSweden School of Informatics Computingand Cyber SystemsNorthern Arizona UniversityFlagstaffAZUSA Department of Ecology and Evolutionary Biology University of ArizonaTucsonAZUSA Department of Geography Wilfrid Laurier UniversityWaterlooONCanada

Background:Most North American temperate forests are plantation or regrowth forests,which are actively *** forests are in different stages of their growth cycles and their ability to sequester atmospheric carbon is affected by extreme weather *** this study,the impact of heat and drought events on carbon sequestration in an age‑sequence(80,45,and 17 years as of 2019)of eastern white pine(Pinus strobus L.)forests in southern Ontario,Canada was examined using eddy covariance flux measurements from 2003 to ***:Over the 17‑year study period,the mean annual values of net ecosystem productivity(NEP)were 180±96,538±177 and 64±165 g C m^(–2)yr^(–1)in the 80‑,45‑and 17‑year‑old stands,respectively,with the highest annual carbon sequestration rate observed in the 45‑year‑old *** found that air temperature(Ta)was the dominant control on NEP in all three different‑aged stands and drought,which was a limiting factor for both gross ecosystem productivity(GEP)and ecosystems respiration(RE),had a smaller impact on ***,the simultaneous occurrence of heat and drought events during the early growing seasons or over the consecutive years had a significant negative impact on annual NEP in all three *** observed a similar trend of NEP decline in all three stands over three consecutive years that experienced extreme weather events,with 2016 being a hot and dry,2017 being a dry,and 2018 being a hot *** youngest stand became a net source of carbon for all three of these years and the oldest stand became a small source of carbon for the first time in 2018 since observations started in ***,in 2019,all three stands reverted to annual net carbon ***:Our study results indicate that the timing,frequency and concurrent or consecutive occurrence of extreme weather events may have significant implications for carbon sequestration in temperate conifer forests in Eastern North *** study is one of few globally available t

关键词： Carbon fluxes Net ecosystem productivity Ecosystem respiration Extreme weather events Drought Temperate forest White pine Eddy covariance

Factors associated with 5-year survival of combined hepatocellular and cholangiocarcinoma

在线全文

学校读者我要写书评

暂无评论

World journal of Hepatology 2020年第11期12卷 1020-1030页

作者： Tomoki Sempokuya eric A Wien Robert j Pattison jihyun Ma Linda L Wong Division of Gastroenterology and Hepatology Department of Internal MedicineUniversity of Nebraska Medical CenterOmahaNE 68198United States Department of Medicine John A.Burns School of MedicineUniversity of Hawaii at ManoaHonoluluHI 96813United States Department of Biostatistics College of Public HealthUniversity of Nebraska Medical CenterOmahaNE 68198United States Department of Surgery John A.Burns School of MedicineUniversity of Hawaii at ManoaHonoluluHI 96817United States

BACKGROUND Combined hepatocellular and cholangiocarcinoma(HCC/CC)is a rare primary hepatic malignancy which carries a poor prognosis due to its aggressive *** centers have enough cases to draw definitive conclusions and there is limited understanding of *** the rarity of HCC/CC,an analysis of large national cancer database was needed to obtain larger number of HCC/CC *** To identify associated factors for 5-year survival of HCC/*** We conducted a retrospective study of The Surveillance,Epidemiology,and End Results(SEER)database obtained from SEER*Stat 8.3.6 *** defined histology code 8180 for the International Classification of Disease for Oncology,3rd edition was used to identify HCC/CC cases from 2004 to *** collected demographics,American joint Committee on Cancer(AjCC)stage,treatment,tumor size,and survival *** data were converted to categorical *** Shapiro-Wilk normality test was used to assess normal ***-Whitney U test was used to compare continuous variables without normal distribution,and t-test was used to compare continuous variables with a normal *** Kaplan-Meier survival curve analyzed 5-year *** and multivariate logistic regression model was used to analyze factors associated with 5-year *** Cox proportional hazard regression was done on 5-year *** defined P<0.05 was statistically *** We identified 497 patients with the following characteristics:Mean age 62.4 years(SD:11.3),149(30.0%)were female,racial distribution was:276(55.5%)white,53(10.7%)black,84(16.9%)Asian and Pacific Islander(API),77(15.5%)Hispanic,and 7(1.4%)others or *** I/II disease occurred in 41.5%and tumor size<50 mm was seen in 35.6%of ***-four(4.8%)received locoregional therapy(LRT),119(23.9%)underwent resection,and 50(10.1%)underwent liver *** overall median survival was 6 mo[Interquartile range(I

关键词： Combined hepatocellular and cholangiocarcinoma Surveillance,Epidemiology,and End Results database Survival Race Hepatobiliary cancer Transplant

Influence of Spinning Variable on the FR Properties of Yarns

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

journal of Donghua University(English Edition) 2003年第2期20卷 48-51页

作者： eric Oyondi Nganyi 郁崇文 College of Textiles Donghua University Shanghai 200051

Broadly considered, spuming variables influences the properties of yarns. However there is scant information on the influence on the fire retardancy (FR) properties. The present work aims to establish the influence of... 详细信息

关键词： Fire retardant fibres yam FR properties fibre distribution

Mode of débitage and technical cognition of hominids at the Guanyindong site

在线全文

学校读者我要写书评

暂无评论

Chinese Science Bulletin 2009年第21期54卷 3864-3871页

作者： LI YingHua HOU YaMei BOEDA eric Department of History Wuhan University Wuhan 430072 China C.N.R.S.-UMR7041 Anthropologie des Techniques des Espaces et des Territoires aux Plio-Pleistocene Maison de I'Archeologie et de I'Ethnologie Nanterre cedex 92023 France Institute of Vertebrate Paleontology and Paleoanthropology Chinese Academy of Sciences Beijing 100044 China joint Laboratory of Human Evolution and Archaeometry Chinese Academy of Sciences Beijing 100044 China

Exploring and interpreting the mode of cognition and behavioral patterns of prehistoric hunter-gatherers is always one of the main goals of current Paleolithic research. In the 1940s, French prehistorians proposed the technological method for studying lithic assemblages which opened a brand-new perspective on the prehistoric domain. In the 1960s, French ethnographer and anthropologist André Leroi-Gourhan proposed the concept "chane opératoire" and established the theory of lithic technological study. After the 1980s, the concept "chane opératoire" was substituted for two different but complementary concepts: techno-cognition and techno-economy, which contributed not only to revealing the technical knowledge and know-how applied during lithic production but also to interpreting the technical behavior of prehistoric hunter-gatherers from social and economic viewpoints. The lithic technological study of the Guanyindong site, presented in this paper, was carried out for the first time by applying lithic technological method developed by French prehistorians to the Chinese materials. Our analytical results demonstrated that the débitage system of Guanyindong is quite distinct from the concept Levallois largely used in Europe, Near-East and Africa. The differentiation between these two débitage modes may contribute to exploring and interpreting the relationship in Middle Paleolithic between China and Europe, Near-East and Africa.

关键词：技术学习认知模式原始人类网站旧石器时代行为模式技术经济人类学家

Use of direct-acting antiviral agents in hepatitis C virusinfected liver transplant candidates

在线全文

学校读者我要写书评

暂无评论

World journal of Gastroenterology 2018年第3期24卷 315-322页

作者： Chiranjeevi Gadiparthi George Cholankeril Brandon j Perumpail eric R Yoo Sanjaya K Satapathy Satheesh Nair Aijaz Ahmed Division of Gastroenterology and Hepatology University of Tennessee Health Sciences CenterMemphisTN 38104United States Division of Gastroenterology and Hepatology Stanford University School of MedicineStanfordCA 94304United States Drexel University College of Medicine PhiladelphiaPA 19129United States Department of Medicine Santa Clara Valley Medical CenterSan JoseCA 95128United States

Since the advent of direct acting antiviral(DAA) agents, chronic hepatitis C virus(HCV) treatment has evolved at a rapid pace. In contrast to prior regimen involving ribavirin and pegylated interferon, these newer agents are highly effective, well-tolerated, have shorter course of therapy and safer essentially in all HCV patients including those with advanced liver disease and following liver transplantation. Clinicians caring for HCV-infected patients on the liver transplant(LT) waitlist are often faced with a dilemma whether to treat HCV infection before or after liver transplantation. Sustained virological response(SVR) rates following HCV treatment may improve hepatic function sufficiently enough to negate the need for LT in certain patients. On the other hand, the decrease in MELD without improvement in quality of life in certain patients may lead to delay or dropout from potentially curative LT surgery list. In this context, our review focuses on the approach to and optimal timing of DAA-based treatment of HCV infection in LT candidates in the peri-transplant period.

关键词： Hepatitis C virus Direct-acting antiviral therapy Liver transplantation Purgatory Model for End-stage liver disease Sustained virological response

Disinfection byproducts in chlorinated or brominated swimming pools and spas: Role of brominated DBPs and association with mutagenicity

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

journal of Environmental Sciences 2022年第7期34卷 253-263页

作者： Hannah K.Liberatore eric j.Daiber Sridevi A.Ravuri judith E.Schmid Susan D.Richardson David M.DeMarini Air Methods and Characterization Division Center for Environmental Measurement and ModelingU.S.Environmental Protection AgencyResearch Triangle ParkNC 27711USA Student Services Authority U.S.Environmental Protection AgencyNational Exposure Research LaboratoryAthensGA 30605USA National Health and Environmental Effects Research Laboratory U.S.Environmental Protection AgencyResearch Triangle ParkNC 27711USA Department of Chemistry and Biochemistry University of South CarolinaColumbiaSC 29208USA

Although the health benefits of swimming are well-documented, health effects such as asthma and bladder cancer are linked to disinfection by-products(DBPs) in pool water. DBPs are formed from the reaction of disinfectants such as chlorine(Cl) or bromine(Br) with organics in the water. Our previous study(Daiber et al., Environ. Sci. Technol. 50, 6652;2016) found correlations between the concentrations of classes of DBPs and the mutagenic potencies of waters from chlorinated or brominated swimming pools and spas. We extended this study by identifying significantly different concentrations of 21 individual DBPs in brominated or chlorinated pool and spa waters as well as identifying which DBPs and additional DBP classes were most associated with the mutagenicity of these waters. Using data from our previous study, we found that among 21 DBPs analyzed in 21 pool and spa waters, the concentration of bromoacetic acid was significantly higher in Brwaters versus Cl-waters, whereas the concentration of trichloroacetic acid was significantly higher in Cl-waters. Five Br-DBPs(tribromomethane, dibromochloroacetic acid, dibromoacetonitrile, bromoacetic acid, and tribromoacetic acid) had significantly higher concentrations in Br-spa versus Cl-spa waters. Cl-pools had significantly higher concentrations of ClDBPs(trichloroacetaldehyde, trichloromethane, dichloroacetic acid, and chloroacetic acid), whereas Br-pools had significantly higher concentrations of Br-DBPs(tribromomethane, dibromoacetic acid, dibromoacetonitrile, and tribromoacetic acid). The concentrations of the sum of all 4 trihalomethanes, all 11 Br-DBPs, and all 5 nitrogen-containing DBPs were each significantly higher in brominated than in chlorinated pools and spas. The 8 Br-DBPs were the only DBPs whose individual concentrations were significantly correlated with the mutagenic potencies of the pool and spa waters. These results, along with those from our earlier study, highlight the importance of Br-DBPs in the muta

关键词： Swimming pools Hot tubs Mutagenicity Disinfection byproducts Spas

The use of shared haplotype length information for pedigree reconstruction in asexually propagated outbreeding crops, demonstrated for apple and sweet cherry

在线全文

学校读者我要写书评

暂无评论

Horticulture Research 2021年第1期8卷 2785-2797页

作者： Nicholas P.Howard Cameron Peace Kevin A.T.Silverstein Ana Poets james j.Luby Stijn Vanderzande Charles-eric Durel Helene Muranty Caroline Denance eric van de Weg Institut fur Biologie und Umweltwissenschaften Carl von Ossietzky UniversityOldenburgGermany Department of Horticultural Science University of MinnesotaSt.PaulMNUSA Department of Horticulture and Landscape Architecture Washington State UniversityPullmanWashingtonWAUSA Minnesota Supercomputing Institute University of MinnesotaMinneapolisMNUSA Universited’Angers Institut AgroINRAEIRHSSFR 4207 QuaSaVBeaucouzeFrance Plant Breeding Wageningen University and ResearchWageningenThe Netherlands

Pedigree information is of fundamental importance in breeding programs and related genetics ***,many individuals have unknown *** methods to identify and confirm direct parent–offspring relationships are routine,those for other types of close relationships have yet to be effectively and widely implemented with plants,due to complications such as asexual propagation and extensive *** objective of this study was to develop and demonstrate methods that support complex pedigree reconstruction via the total length of identical by state haplotypes(referred to in this study as“summed potential lengths of shared haplotypes”,SPLoSH).A custom Python script,HapShared,was developed to generate SPLoSH data in apple and sweet *** was used to establish empirical distributions of SPLoSH data for known relationships in these *** distributions were then used to estimate previously unknown *** studies in each crop demonstrated various pedigree reconstruction scenarios using SPLoSH *** cherry,a full-sib relationship was deduced for‘Emperor Francis,and‘Schmidt’,a half-sib relationship for‘Van’and‘Windsor’,and the paternal grandparents of‘Stella’were *** apple,29 cultivars were found to share an unknown parent,the pedigree of the unknown parent of‘Cox’s Pomona’was reconstructed,and‘Fameuse’was deduced to be a likely grandparent of‘McIntosh’.Key genetic resources that enabled this empirical study were large genome-wide SNP array datasets,integrated genetic maps,and previously identified pedigree *** with similar resources are also expected to benefit from using HapShared for empowering pedigree reconstruction.

关键词： Python breeding crops