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An ACO-RFD hybrid method to solve NP-complete problems

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Frontiers of Computer Science 2013年第5期7卷 729-744页

作者： pablo RABANAl Ismael RODRIGUEZ Fernando RUBIO Dept. Sistemas Inforrnaiticos y Computacion Facultad de Informatica Universidad Complutense de Madrid Madrid 28040 Spain

In this paper we hybridize ant colony optimiza- tion （ACt） and river formation dynamics （RFD）, two related swarm intelligence methods. In ACt, ants form paths （prob- lem solutions） by following each other＇s pheromone trails and reinforcing trails at best paths until eventually a single path is followed. On the other hand, RFD is based on copy- ing how drops form rivers by eroding the ground and de- positing sediments. In a rough sense, RFD can be seen as a gradient-oriented version of ACt. Several previous experi- ments have shown that the gradient orientation of RFD makes this method solve problems in a different way as ACt. In particular, RFD typically performs deeper searches, which in turn makes it find worse solutions than ACt in the first exe- cution steps in general, though RFD solutions surpass ACt solutions after some more time passes. In this paper we try to get the best features of both worlds by hybridizing RFD and ACt. We use a kind of ant-drop hybrid and consider both pheromone trails and altitudes in the environment. We apply the hybrid method, as well as ACt and RFD, to solve two NP-hard problems where ACt and RFD fit in a different manner： the traveling salesman problem （TSP） and the prob- lem of the minimum distances tree in a variable-cost graph （MDV）. We compare the results of each method and we an- alyze the advantages of using the hybrid approach in each case.

关键词： river formation dynamics ant colony optimization heuristic algorithms NP-hard problems

Parallel array with axially coded light-sheet microscope

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light(Science & Applications) 2020年第1期9卷 1387-1388页

作者： pablo loza-Alvarez ICFO-The Institute of Photonic Sciences The Barcelona Institute of Science and Technology08860 CastelldefelsBarcelonaSpain

A parallel array of frequency modulated light sheets results in a scanning-less light sheet microscope capable of fast volumetric imaging.

关键词： array light axial

Failure rate,return-to-sports and magnetic resonance imaging after meniscal repair:119 patients with 7 years mean follow up

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世界骨科杂志:英文版 2023年第8期14卷 612-620页

作者： Juan pablo Zicaro Nicolas Garrido Ignacio Garcia-Mansilla Carlos Yacuzzi Matias Costa-Paz Department of Knee Hospital Italiano de Buenos AiresBuenos Aires 1109Argentina

BACKGROUND One of the most important factors to consider in relation to meniscal repair is the high failure rate reported in the existing *** To evaluate failure rates,return to sports(RTS)rate,clinical outcomes and magnetic resonance image(MRI)evaluation after meniscus suture repair for longitudinal tears at a minimum *** We conducted a retrospective review of meniscal repairs between January 2004 and December *** patients treated for longitudinal tears associated or not with an anterior cruciate ligament reconstruction(ACl-R)were *** ramp lesions,radial and root tears,associated with multiligament injuries,tibial fracture and meniscal allograft transplants were *** details and failure rate,defined as symptomatic patients who underwent a revision surgery,were *** isolated bucket handle tears(BHTs)were usually associated with higher failure rates,we compared BHTs and not BHTs associated or not with an *** 2014,the inside-out technique using cannulas and suture needles with 2-0 Tycron began to *** addition,the number of stitches per repair was *** view of differences in surgical technique,we compared two different cohorts:before and after *** recorded the RTS according to the level achieved and the time to *** and IKDC scores were *** were studied with x-rays and MRI as standard postoperative *** One hundred and nineteen patients were included with a mean follow up of 7 years(SD:4.08).Overall failure rate was 20.3%at a mean 20.1 *** statistically significant differences were found when comparing failure for medial and lateral meniscal repair(22.7%and 15.3%,P=0.36),BHTs and not BHTs(26%and 17.6%,P=0.27),isolated or associated with an ACl-R(22.9%and 18%,P=0.47),or when comparing only BHTs associated with an ACl-R(23%and 27.7%,P=0.9)or *** comparing cohorts before and after 2014,we found a significant decrease in the overall f

关键词： Meniscus repair Bucket handle tears Meniscal suture Failure rate longitudinal meniscus tears

Numerical and experimental investigation to design a novel morphing airfoil for performance optimization

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Propulsion and Power Research 2023年第1期12卷 83-103页

作者： Kiumars Khani Aminjan Maryam Ghodrat Milad Heidari Pooyan Rahmanivahid Shayan Naghdi Khanachah Mira Chitt Juan pablo Escobedo-Diaz Faculty of Aerospace Malek Ashtar University of TechnologyTehran 1774-15875Iran School of Engineering and Information Technology University of New South Wales CanberraCanberraACT 2610Australia Mechanical Engineering Department Global College of Engineering and Technology(GCET)P.O.Box 2546 CPO Ruwi 112MuscatSultanate of Oman School of Industrial Engineering Iran University of Science and TechnologyTehran 16846-13114Iran

Optimizing flying objects’wing performance has attracted a significant attention in the last few *** this article,some of the main mechanisms for changing the geometry of the wing were investigated and a new mechanism is proposed to improve the aerodynamic performance of the airplane *** designs have been simulated and analyzed from both aerodynamic and control points of *** aerodynamic simulations using CFD methods,two airfoils of NACA series 6 with specifications 65-212 and 65-2012 were *** results indicated that both airfoils used have a better performance compared to others in a certain range of the angle of ***,a new mechanism is proposed to change the wing geometry to optimize its *** the proposed mechanism,the structures of airfoils and wings consist of two fixed and moving parts,which can change their geometry with the help of a control *** fixed part has a grooved track,and as the moving part moves in the direction of the grooves,the curvature of the upper and lower parts of the wing *** design control circuit includes an angle sensor,a micro controller,and a *** CFD results are entered into the micro controller as *** any moment,the micro controller receives the angle data from the angle sensor and by comparing them with the CFD data,and issuing a command to the servomotor,it situates the wing curvature in the optimal state at all *** built mechanism was tested at an attack angle of 0°and 25°.The results showed that the different parts of the mechanism work with very high precision and put the geometric shape of the wing in an optimal state in a completely intelligent *** should be noted that the average error in test for t/c and Xt/c was 15.3% and 9%,respectively.

关键词： Morphing airfoil lift force Optimization Computational fluid dynamics Micro controller Angle sensor

Calcitriol induces post-thawed bovine sperm capacitation

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BIOCEll 2023年第5期47卷 1135-1143页

作者： ANA CECIlIA lIAUDAT FRANCISCA EBEl BIANCA ANA OPIZZO MARINA AURORA GONZAlEZ DAMIÁN BlOIS pablo BOSCH NANCY RODRIGUEZ Departamento de Biología Molecular Instituto de Biotecnología Ambiental y Salud(INBIAS)Río Cuarto5800Argentina

Background:Capacitation is a set of physiological changes sperms undergo to acquire fertilizing *** vivo,this process is directly associated with high calcium levels in sperm ***,the vitamin D hypercalcemic metabolite,is related to human sperm motility,capacitation,and acrosome *** work aimed to study the effect of calcitriol on bull sperm quality parameters and ***:One million freezethawed spermatozoa were obtained from different bulls and treated with 20 nM of calcitriol for 30 *** cells(negative control)and treated ones with calcitriol or heparin(100μg/ml,positive capacitation control)were evaluated for motility,viability,and functional ***(70μM,30 min)treatment was included as a reactive oxygen species(ROS)positive sperm ***:The results elucidated that sperm exposed to 20 nM calcitriol showed higher viability,vigor,and capacitation than their positive and negative *** percentage of sperm with intact plasma and acrosome membranes,mitochondrial membrane potential(ΔΨm),and phosphatidylserine externalization was similar in all the conditions evaluated,while ROS production was higher with heparin and menadione-treated groups than the calcitriol group or negative ***:Our results indicate that calcitriol induces the capacitation of thawed bull spermatozoa and maintains acceptable values of progressive motility,viability,and vigor without altering key biological parameters such as redox status,ΔΨm,and cell death.

关键词： Bovine Sperm capacitation Calcitriol Cell viability Plasma membrane integrity Reactive oxygen species

Revision anterior cruciate ligament reconstruction:Return to sports at a minimum 5-year follow-up

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World Journal of Orthopedics 2022年第9期13卷 812-824页

作者： Ezequiel Ortiz Juan pablo Zicaro Ignacio Garcia Mansilla Carlos Yacuzzi Matias Costa-Paz Knee Division Hospital Italiano de Buenos AiresCiudad Autónoma 1181Buenos AiresArgentina

BACKGROUND Between 43%and 75%of patients who undergo primary anterior cruciate ligament(ACl)surgery return to sport ***,after a revision ACl reconstruction(AClR)the rate of return to sports is variable.A few publications have reported returns to sports incidence between 56%to 100%after revision *** To determine return to sports and functional outcomes after a single-stage revision AClR with a 5-year minimum follow-up at a single *** All patients operated between 2010 and 2016 with a minimum 5 years of followup were *** of sport,intensity,frequency,expectation,time to return to sport and failure rate were ***,Tegner and International Knee Documentation Committee forms were evaluated prior to the first AClR surgery,at 6 mo after primary surgery and after revision AClR at 5 years minimum of *** stability was tested with the knee arthrometer test(KT-1000 knee arthrometer,Medmetric Corp).RESUlTS A total of 41 patients who underwent revision AClR during that period of time were contacted and available for *** patient age at time of revision was 29 years old[interquartile range(IQR):24.0-36.0],and 39(95.0%)were *** median time from revision procedure to follow-up was 70 mo(IQR:58.0-81.0).Regarding return to sports,16(39.0%)were at the same level compared to preinjury period,and 25 patients(61.0%)returned at a lower ***-three percent categorized the sport as very important and 37.0%as *** patient(2.4%)failed with a recurrent ACl *** preoperative lysholm and(SD)16]and 50(SD 11),*** follow-up,mean lysholm and subjective International Knee Documentation Committee scores were 89(SD 8)and 82(SD 9)(P=0.0001).Mean Tegner score prior to primary AClR was 6.7(SD 1.3),5.1(1.5 SD)prior to revision AClR and 5.6(1.6 SD)at follow-up(P=0.0002).Overall,knee arthrometer test measurement showed an average of 6 mm(IQR:4.0-6.0)side-to-side difference of displacement pri

关键词： Return to sport Revision anterior cruciate ligament Arthroscopy Knee Functional outcome

Multiscale modeling of ultrafast melting phenomena

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npj Computational Materials 2022年第1期8卷 324-333页

作者： Gaetano Calogero Domenica Raciti pablo Acosta-Alba Fuccio Cristiano Ioannis Deretzis Giuseppe Fisicaro Karim Huet Sébastien Kerdilès Alberto Sciuto Antonino la Magna CNR IMM CataniaItaly UniversitéGrenoble Alpes CEA-LETIGrenobleFrance lAAS CNRSUniversitéde ToulouseToulouseFrance laser Systems&Solutions of Europe(lASSE) GennevilliersFrance Dipartimento di Fisica e Astronomia Universitàdi CataniaCataniaItaly

Ultraviolet Nanosecond laser Annealing(lA)is a powerful tool for both fundamental investigations of ultrafast,nonequilibrium phase-change phenomena and technological applications(e.g.,the processing of 3D sequentially integrated nano-electronic devices)where strongly confined heating and melting is *** the lA process along with the experimental design is challenging,especially when involving complex 3D-nanostructured systems with various shapes and *** this purpose,it is essential to model critical nanoscale physical lA-induced phenomena,such as shape changes or formation and evolution of point and extended *** date,lA simulators are based on continuum models,which cannot fully capture the microscopic kinetics of a solid–liquid *** this work a fully atomistic lA simulation methodology is presented,based on the parallel coupling of a continuum,finite elements,μm-scale electromagnetic-thermal solver with a super-lattice Kinetic Monte Carlo atomistic model for *** against phase-field models and experimental data validate the *** of a Si(001)surface is studied varying laser fluence and pulse shape,assuming both homogeneous and inhomogeneous nucleation,revealing how liquid Si nuclei generate,deform and coalesce during *** proposed methodology is applicable to any system where the atom kinetics is determined by a strongly space-and time-dependent field,such as temperature or strain.

关键词： kinetics shape melting

Psychiatrists' approach to vascular risk assessment in latin America

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World Journal of Psychiatry 2014年第3期4卷 56-61页

作者： pablo Richly pablo lópez Ezequiel Gleichgerrcht Daniel Flichtentrei María Prats Ricardo Mastandueno Julián Bustin Marcelo Cetkovich-Bakmas INECO (Institute of Cognitive Neurology) Buenos Aires C1126AAB Argentina Institute of Neurosciences Favaloro University Buenos Aires C1093AAS Argentina UDP-INECO Foundation Diego Portales University Santiago de Chile 8370076 Chile Intramed Buenos Aires B1636AJK Argentina

AIM: To explore the way in which latin American psychiatrists approach the screening of vascular risk factors in patients receiving antipsychotic ***: This was a descriptive, cross sectional study that surveyed latin-American physicians to evaluate differences between groups divided in three main sections. The first section included demographic and professional data. The second section asked about the available medical resources: weighing scales, sphygmomanometer and measuring tape. Finally, the third section aimed at looking into the attitudes towards car-diovascular prevention. The latter was also divided into two subsections. In the first one, the questions were about weight, blood pressure and waist perimeter. In the second subsection the questions asked about the proportion of patients:(1) that suffered from overweight and/or obesity;(2) whose lipids and glycemia were controlled by the physician;(3) that were questioned by, and received information from the physician about smoking; and(4) that received recommendations from the physician to engage in regular physical activity. The participants were physicians, users of the medical website Intramed. The visitors were recruited by a banner that invited them to voluntarily access an online self-reported structured questionnaire with multiple options. RESUlTS: We surveyed 1185 general physicians and 792 psychiatrists. Regarding basic medical resources, a significantly higher proportion of general physicians claimed to have weighing scales(χ2 = 404.9; P le general physicians measured overweight and metabolic indexes in the general population in a higher proportion than in patients treated with antipsychotics(Z =-11.91; P laimed to measure them in patients medicated with antipsychotics in a higher proportion than in the general population(Z =-3.26; P lso general physicia

关键词： Antipsychotics Metabolic syndrome Psychiatric patients Schizophrenia Vascular risk factors

Bridging Methods for Atomistic-to-Continuum Coupling and Their Implementation

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Communications in Computational Physics 2010年第4期7卷 831-876页

作者： pablo Seleson Max Gunzburger Department of Scientific Computing Florida State UniversityTallahasseeFL 32306-4120USA

Several issues connected with bridging methods for atomistic-to-continuum(AtC)coupling are *** coupling approaches using various energy blending models are studied as well as the influence that model parameters,blending functions,and grids have on simulation *** use the lagrange multiplier method for enforcing constraints on the atomistic and continuum displacements in the bridge *** also show that continuum models are not appropriate for dealing with problems with singular loads,whereas AtC bridging methods yield correct results,thus justifying the need for a multiscale *** investigate models that involve multiple-neighbor interactions in the atomistic region,particularly focusing on a comparison of several approaches for dealing with Dirichlet boundary conditions.

关键词： Multiscale modeling atomistic-to-continuum coupling boundary treatment