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Experimental assessment of arsenic toxicity in garole sheep in India

Emerging Contaminants 2016年第3期2卷 128-134页

作者： Chinmoy Maji Samar Sarkar Suman Biswas pabitra hriday patra Bakul Kumar Datta Samiran Bandyopadhyay Tapas Kumar Biswas Chandrakanta Jana Tapan Kumar Mandal Department of Veterinary Medicine Ethics&JurisprudenceFaculty of Veterinary and Animal SciencesWest Bengal University of Animal and Fishery SciencesKolkataWest BengalIndia Department of Veterinary Pharmacology and Toxicology Faculty of Veterinary and Animal SciencesWest Bengal University of Animal and Fishery SciencesKolkataWest BengalIndia Indian Veterinary Research Institute Eastern Regional StationKolkataWest BengalIndia Indian Veterinary Research Institute Regional Station MukteswarMukteshwarUttarakhandIndia

Arsenic,a dangerous bio-accumulative poison,is a grave threat affecting a large number of people as well as animals throughout theWorld,particularly in Bangladesh and West Bengal,*** is also a matter of concern as continuously entering into food chain through biotic and abiotic *** present study was conducted to evaluate the experimental effect of arsenic toxicosis on Garole sheep of West *** group was subjected to oral arsenic exposure@6.6 mg Kg1 over 133 days when rests considered as negative *** arsenic estimation in wool,urine and feces along with hemato-biochemical alteration were checked *** was evident from the study that long term arsenic exposure exerted a significant(p<0.01)alteration compared to normal animal which were further supported by clinical *** animals showed histological changes throughout major internal organs like coagulative necrosis of liver,tubular nephritis of kidney and acanthosis of skin *** bioaccumulative and excretion pattern of arsenic inside body were also well understood by the arsenic estimation study of wool,urine and feces which may be helpful for discussion regarding arsenic entry into food chain via animals.

关键词： Arsenic Garole sheep Excretion Bioaccumulation Liver Kidney

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