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Preoperative rectosigmoid endoscopic ultrasonography predicts the need for bowel resection in endometriosis

World Journal of Gastroenterology 2019年第6期25卷 696-706页

作者： Victor Desplats René-Louis Vitte Joseph du Cheyron Gilles Roseau Arnaud Fauconnier Frédérick Moryoussef Department of Hepato-gastroenterology Centre Hospitalier Intercommunal Poissy Saint Germain Department of Statistics Centre Hospitalier Intercommunal Poissy Saint Germain Department of Gastroenterology H?pital Cochin Department of Obstetrics and Gynecology Centre Hospitalier Intercommunal Poissy Saint Germain University of Saint Quentin en Yvelines

BACKGROUND Rectosigmoid endometriosis is an underdiagnosed disease responsible for abdominal pain, transit disorders and rectal bleeding. Two surgical approaches,rectosigmoid bowel resection(segmental or patch) or intramuscular layer dissection(shaving), are *** To assess whether the lesion features observed via preoperative rectosigmoid endoscopic ultrasonography(RS-EUS) might predict the need for bowel *** This multicentric retrospective study was conducted on patients with rectosigmoid endometriosis who underwent a curative surgical procedure,evaluated by RS-EUS performed by two trained operators, between January 2012 and March 2018. A univariate statistical analysis was performed on nodules' RSEUS features(thickness, width, infiltration of the submucosae, presence of a bump into the digestive lumen and presence of multiple rectosigmoid localizations). A multivariate logistic regression was then performed on the significant *** Of the 367 patients, 73 patients with rectosigmoid endometriosis were evaluated by RS-EUS and underwent rectosigmoid surgery. After the univariate analysis was completed, thickness, width and infiltration of the submucosae were identified as potential predictive factors for bowel resection. In a multivariate logistic regression model, only thickness appeared to be a significant [odds ratio(OR) = 1.49, 95% confidence interval(CI): 1.04-2.12, P = 0.028] predictive factor for bowel resection. Receiver operating characteristic analysis performed showed that a thickness over 5.20 mm might be used as cut-off with a sensitivity of 76%, a specificity of 81%, and an area under carve = 0.82. The cut-off values for 100%sensitivity and 100% specificity were 0.90 mm and 10.00 mm, respectively. A trend concerning width to predict the need for resection was also observed(OR1.12, 95%CI: 1.00-1.26, P = 0.054)CONCLUSION The presence of a rectosigmoid nodule of endometriosis greater than 5.20 mm thick on RS-EUS might predi

关键词： Endometriosis Surgery Endoscopy Ultrasound Bowel disease Rectum and sigmoid

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Irrigated pinto bean crop stress and yield assessment using ground based low altitude remote sensing technology

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Information Processing in Agriculture 2019年第4期6卷 502-514页

作者： Rakesh Ranjan Abhilash KChandel Lav R.Khot Haitham YBahlol Jianfeng Zhou rick ABoydston Phillip NMiklas Department of Biological Systems Engineering Washington State UniversityPullmanWAUSA Center for Precision and Automated Agricultural Systems IARECWashington State UniversityProsserWAUSA USDA-ARS Grain Legume Genetics and Physiology Research Unit ProsserWA USA

The pinto bean is one of widely consumed legume crop that constitutes over 42%of the U.S dry bean ***,limited studies have been conducted in past to assess its quantitative and qualitative yield *** remote sensing technologies can help in such ***,this study evaluates the role of ground-based multispectral imagery derived vegetation indices(VIs)for irrigated the pinto bean stress and yield *** were eight cultivars of the pinto bean grown under conventional and strip tillage treatments and irrigated at 52%and 100%of required *** data was acquired using a five-band multispectral imager at early,mid and late growth *** used 25 broadband VIs were derived to capture crop stress traits and yield *** component analysis and Spearman’s rank correlation tests were conducted to identify key VIs and their correlation(rs)with abiotic stress at each growth *** difference vegetation index,nonlinear vegetation index(NLI),modified NLI and infrared percentage vegetation index(IPVI)were consistent in accounting the stress response and crop yield at all growth stages(rs>0.60,coefficient of determination(R2):0.50–0.56,Pcantly accounted for crop stress at early and late ***,identified key VIs may be helpful to growers for precise crop management decision making and breeders for crop stress response and yield assessments.

关键词： Pinto bean Multispectral imaging Vegetation indices Stress assessment Yield potential

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Retall Bussiness Kit FOR DUMMIES 2

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2008年

作者： rick Seger

ISBN: (数字)9780470422571

ISBN: (纸本)9780470293300

Whether you’re a novice or a seasoned retail entrepreneur, Retail Business Kit For Dummies shows you how to start and run your business in today’s retail marketplace—from your original dream and the day-to-day operation to establishing a connection with customers and increasing your sales, both on the Web and at a brick-and-mortar shop. In this practical, how-to guide, retail expert rick

关键词： New business enterprisesManagement.Retail tradeManagement.Stores RetailManagement.

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Avatar in Zhangjiajie

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国际人才交流 2011年第12期 62-63页

作者： rick Hong 不详

Zhangjiajie is situated in the northwest of Hunan Province,about 400 kilometers away from Changsha,the capital city of Hunan,covering a total area of 9,563 square kilometers,of which 76% are in mountainous *** of its ... 详细信息

关键词：张家界英语美文英语阅读优秀作文

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Signal transduction mediated by Bid, a pro-death Bcl-2 family proteins, connects the death receptor and mitochondria apoptosis pathways

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Cell Research 2000年第3期10卷 161-167页

作者： YIN XIAO-MING (Department of pathology, University of Pittsburgh School of Medicine, 3550 terrace Street, Pittsburgh, pa 15261, USA) Department of pathology University of Pittsburgh School of Medicine Pittsburgh USA

Two major apoptosis pathways have been defined in mammalian cells, the Fas/TNF-R1 death receptor pathway and the mitochondria pathway. The Bcl-2 family proteins consist of both anti-apoptosis and pro- apoptosis members that regulate apoptosis, mainly by controlling the release of cytochrome c and other mitochondrial apoptotic events. However, death signals mediated by Fas/TNF-R1 receptors can usually activate caspases directly, bypassing the need for mitochondria and escaping the regulation by Bcl-2 family proteins. Bid is a novel pro-apoptosis Bcl-2 family protein that is activated by caspase 8 in response to Fas/TNF-R1 death receptor signals. Activated Bid is translocated to mitochondria and induces cytochrome c release, which in turn activates downstream caspases. Such a connection between the two apoptosis pathways could be important for induction of apoptosis in certain types of cells and responsible for the pathogenesis of a number of human diseases.

关键词： Apoptosis Bcl-2 family proteins Bid Fas TNF.

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EXISTENCE OF THE MINIMAL POSITIVE SOLUTION OF SOME NONLINEAR ELLIPTIC SYSTEMS WHEN THE NONLINEARITY IS THE SUM OF A SUBLINEAR AND A SUPERLINEAR terM

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Applied Mathematics and Mechanics(English Edition) 2000年第3期21卷 283-290页

作者： Nicolae Tarfulea (Department of Mathematics, the Pennsylvania State University, University park, pa 16802, U S A) Department of Mathematics the Pennsylvania State University University Park U S A

It is shown that there exists Λ>0 such that, for every λ∈(0,Λ), the semilinear elliptic system: - Δ u=λu｜u｜ q-1 +u｜u｜ p-1 -v inΩ, - Δ v=δu-γv in Ω, u=v=0 on Ω, where Ω∈R N(N≥2) is a b... 详细信息

It is shown that there exists Λ>0 such that, for every λ∈(0,Λ), the semilinear elliptic system: - Δ u=λu｜u｜ q-1 +u｜u｜ p-1 -v inΩ, - Δ v=δu-γv in Ω, u=v=0 on Ω, where Ω∈R N(N≥2) is a bounded domain with smooth boundary and 0

关键词： reaction diffusion system positive solution nonlinear equation

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HNF1A mutation in a Thai patient with maturity-onset diabetes of the young: A case report

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World Journal of Diabetes 2019年第7期10卷 414-420页

作者： Nattachet Plengvidhya Watip Tangjittipokin Nipaporn Teerawattanapong Tassanee Narkdontri pa-thai Yenchitsomanus Division of Endocrinology and Metabolism Department of MedicineFaculty of Medicine Siriraj HospitalMahidol UniversityBangkok 10700Thailand Siriraj Center of Research Excellence for Diabetes and Obesity Faculty of Medicine Siriraj HospitalMahidol UniversityBangkok 10700Thailand Department of Immunology Faculty of Medicine Siriraj HospitalMahidol UniversityBangkok 10700Thailand Research Division Department of Research and DevelopmentFaculty of Medicine Siriraj HospitalMahidol UniversityBangkok 10700Thailand Siriraj Center of Research Excellence for Molecular Medicine Faculty of Medicine Siriraj HospitalMahidol UniversityBangkok 10700Thailand

BACKGROUND Maturity-onset diabetes of the young(MODY)is the most common form of monogenic *** disease is transmitted in autosomal dominant mode and diabetes is usually diagnosed before age 25 *** 3 is caused by mutation of hepatocyte nuclear factor(HNF)1A genes and is the most common MODY *** of MODY 3 is crucial since glycemic control can be accomplished by very low dose of *** this report we described a Thai MODY 3 patient who had excellence plasma glucose control by treating with glicazide 20 mg per day and insulin therapy can be *** SUMMARY A 31-year-old woman was diagnosed diabetes mellitus at 14 years *** disease was transmitted from her grandmother and mother compatible with autosomal dominant *** sequencing of proband’s DNA identified mutation of HNF1A at codon 203 which changed amino acid from arginine to cysteine(R203C).This mutation was carried only by family members who have *** patient has been treated effectively with a combination of oral hypoglycemic agents and must include a very low dose of glicazide(20 mg/d).Insulin therapy was successfully *** We demonstrated a first case of pharmacogenetics in Thai MODY 3 *** findings underscore the essential role of molecular genetics in diagnosis and guidance of appropriate treatment of diabetes mellitus in particular patient.

关键词： Oral sulfonylureas Maturity-onset diabetes of the young HNF1A case report

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Effects of titanium addition on structural, mechanical, tribological, and corrosion properties of Al-25Zn-3Cu and Al-25Zn-3Cu-3Si alloys

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Transactions of Nonferrous Metals Society of China 2020年第2期30卷 303-317页

作者： Ali pa?a HEK?MO?LU Merve ?ALI? Mechanical Engineering Department Engineering Faculty Recep Tayyip Erdo?an University

To investigate the effect of grain refinement on the material properties of recently developed Al-25 Zn-3 Cu based alloys,Al-25 Zn-3 Cu,Al-25 Zn-3 Cu-0.01 Ti,Al-25 Zn-3 Cu-3 Si and Al-25 Zn-3 Cu-3 Si-0.01 Ti alloys were produced by permanent mold casting *** of the alloys were examined by *** and mechanical properties of the alloys were determined by Brinell method and tensile tests,*** characteristics of the alloys were investigated by a ball-on-disc type test *** properties of the alloys were examined by an electrochemical corrosion experimental *** was observed that microstructure of the ternary A1-25 Zn-3 Cu alloy consisted ofα,α+ηandθ(Al2Cu)*** was also observed that the addition of 3 wt.%Si to A1-25Zn-3Cu alloy resulted in the formation of silicon particles in its *** addition of 0.01 wt.%Ti to the Al-25Zn-3Cu and Al-25 Zn-3 Cu-3 Si alloys caused a decrement in grain size by approximately 20%and 39%and an increment in hardness from HRB 130 to 137 and from HRB 141 to 156,*** strengths of these alloys increased from 278 to 297 Mpa and from 320 to 336 Mpa while their tensile strengths increased from 317 to 340 Mpa and from 334 to 352 *** resistance of the alloys increased,but corrosion resistance decreased with titanium addition.

关键词： Al-Zn-Cu alloy as-cast microstructure characterization corrosion fracture friction and wear characteristics mechanical properties

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同型半胱氨酸、低密度脂蛋白胆固醇及糖化血红蛋白在2型糖尿病视网膜病变的影响研究

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齐齐哈尔医学院学报 2024年第2期45卷 124-128页

作者：帕里杂·赛力克侯志梅舒哈尔新疆医科大学第二临床医学院新疆乌鲁木齐830000 克拉玛依市中心医院新疆克拉玛依834000

目的探讨血清同型半胱氨酸(Hcy)、低密度脂蛋白胆固醇(LDL-C)及糖化血红蛋白(HbA1c)在2型糖尿病视网膜病变(DR)中的影响。方法回顾性分析2019年4月—2022年6月本院内分泌科住院的2型糖尿病患者有糖尿病视网膜病变组(DR组)患者150例和非... 详细信息

目的探讨血清同型半胱氨酸(Hcy)、低密度脂蛋白胆固醇(LDL-C)及糖化血红蛋白(HbA1c)在2型糖尿病视网膜病变(DR)中的影响。方法回顾性分析2019年4月—2022年6月本院内分泌科住院的2型糖尿病患者有糖尿病视网膜病变组(DR组)患者150例和非糖尿病视网膜病变(NDR组)患者150例的临床资料,包括每位患者的一般资料、生化指标。比较两组间的一般信息;分析DR组与NDR组的影响因素;多元素回归分析DR的危险因素。结果DR及NDR组患者年龄、病程方面差距具有统计学意义(P<0.05)。DR组患者Hcy、FBG、TG、LDL-C、HbA1c水平明显高于NDR组(P<0.05)。Pearson相关系数分析,DR组患者的Hcy与年龄,病程FBG、TG、TC、LDL-c、HbA1c呈正相关关系(P<0.05)。Logistics回归分析结果显示病程、TG、LDL-c、Hcy、HbA1c均是影响2型糖尿病视网膜病变的独立因素(P<0.05)。结论Hcy、LDL-c、HbA1c水平在DR患者中远高于NDR患者,三者与DR发生、发展存在一定联系,临床可根据其表达水平对患者病情变化进行有效评估。

关键词：糖尿病视网膜病变同型半胱氨酸 2型糖尿病低密度脂蛋白糖化血红蛋白

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Age-old Questions Continue to Entice Scientists

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当代外语研究 2005年第10期 2-5页

作者： rick Weiss 何珊

要是科学家们承认自己无知,那可真是新鲜事。就在前不久,《科学》杂志公布了科学家们认为目前还无法解答,但很有可能在今后25年里得到解答的125个问题,这个列表是通过对100多名在各个学科的主要研究人员进行问卷调查得出的。下面就让我... 详细信息

要是科学家们承认自己无知,那可真是新鲜事。就在前不久,《科学》杂志公布了科学家们认为目前还无法解答,但很有可能在今后25年里得到解答的125个问题,这个列表是通过对100多名在各个学科的主要研究人员进行问卷调查得出的。下面就让我们来看看哪些问题是科学家最想解答的。

关键词：科学家研究人员解答问卷调查前不久无知问题承认学科公布

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