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Journal of Thermal Science 2020年第1期29卷 115-121页

作者： ma Xin TU Ran CHENG Xudong ZHU Shuguang SUN Qiang FANG Tingyong College of Environment and Energy Engineering Anhui Jianzhu UniversityHefei 230022China College of Mechanical Engineering and Automation Huaqiao UniversityXiamen 361021China State Key Laboratory of Fire Science University of Science and Technology of ChinaHefei 230026China

Rigid polyurethane(PUR)foam,a sustainable thermosetting building facade porous polymer material,has been widely applied in the construction industry for energy *** knowledge of the fire safety performance of PUR foam at different altitudes and sample widths is *** lab-scale experiments were conducted in the Lhasa plateau(66.5 kpa)and the Hefei plain(99.8 kpa)in *** propagation characteristics(average flame spread rate and flame height)were measured at different widths and atmospheric pressures of the test *** results show that the dependence of dimensionless flame heights on sample width shows negative power law relationships with index of−w/5.4 to−w/*** flame height and flame spread rate were lower under low ambient pressure conditions as H fP0.26~0.33 and VfP0.057~*** spread rate decreased with increasing sample width in the convection regime before a critical width of 4 cm–8 cm,after which the flame spread rate increased in the radiation *** of this study contribute to the science of combustion,fire safety and energy conservation,and provide a basis for fire safety protocols for historical heritage buildings in the Lhasa plateau.

关键词： rigid polyurethane low air pressure building facade energy conservation heat transfer

Hepatitis B virus X protein modulates the apoptosis of hepatoma cell line induced by TRAIL

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Science China(Life Sciences) 2005年第3期48卷 277-286页

作者： LIANG Xiaohong 1 , SUN Wensheng 1 , GAO Lifen 1 , ma Chunhong 1 , HAN Lihui 1 & CHEN Youhai 2 1. Institute of Immunology, Medical School of Shandong University, Jinan 250012, China 2. Department of pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia pa19104, USA Institute of Immunology Medical School of Shandong University Jinan China Department of pathology and Laboratory Medicine University of Pennsylvania Philadelphia USA

The purpose of this study is to observe the effects of HBx on the apoptosis of hepatoma cells induced by TNF-related apoptosis-inducing ligand (TRAIL) and to study prelimi- nary molecular mechanisms for its effects. In order to set up a model in vitro, BEL7402-HBx cell line, stably expressing HBx mRNA, was established by stable transfection of pcDNA-HBx, which contains HBx gene, into hepatoma cell line BEL7402. Control cell line BEL7402-cDNA3, stably transfected with pcDNA3, was set up simultaneously as a control. Trypan blue exclusion test, caspase 3 activity detection and TUNEL assay were performed to detect the apoptosis of BEL7402, BEL7402-cDNA3, BEL7402-HBx induced by TRAIL. The expression of TRAIL recep- tors in three groups was analyzed by Flow cytometry. In addition, phosphorothioated antisense oligonucleotide against the translation initial region of HBx gene (PS-asODNs/HBx) was used to block the expression of HBx in HepG2.2.15 cells and to further confirm the effects of HBx on TRAIL-induced apoptosis. Trypan blue exclusion test indicated that TRAIL had a dose-dependent cytotoxicity on BEL7402, BEL7402-cDNA3 and BEL7402-HBx cells. Under treatment of the same concentration of TRAIL, BEL7402-HBx had a higher apoptosis rate and a higher level of Caspase 3 activation than BEL7402 and BEL7402-cDNA3. TUENL assay showed that the apoptosis rate of BEL7402-HBx induced by 10 μg/L TRAIL was 41.4%±7.2%, signifi- cantly higher than that of BEL7402 and BEL7402-cDNA3 cells. Blockade of HBx expression in Hep G2.2.15 cells partly inhibited the apoptosis induced by TRAIL. The introduction or blockade of HBx did not change the expression pattern of TRAIL receptors. The present study firstly con- firms the effects of HBx on TRAIL- induced apoptosis from two different points and it is not re- lated with the expression level of TRAIL receptors. This would be useful to further clarify the roles of imbalanced apoptosis in pathogenesis of Hepatitis B and related hepatocellular carc

关键词： apoptosis, TRAIL, hepatitis B virus X protein, phosphorothioated antisense oligonucleotide.

A high sensitive 66 dB linear dynamic range receiver for 3-D laser radar

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Journal of Semiconductors 2017年第8期38卷 81-86页

作者： Rui ma Hao Zheng Zhangming Zhu School of Microelectronics Xidian University

This study presents a CMOS receiver chip realized in 0.18μm standard CMOS technology and in- tended for high precision 3-D laser radar. The chip includes an adjustable gain transimpedance pre-amplifier, a post-amplifier and two timing comparators. An additional feedback is employed in the regulated cascode tran- simpedance amplifier to decrease the input impedance, and a variable gain transimpedance amplifier controlled by digital switches and analog multiplexer is utilized to realize four gain modes, extending the input dynamic range. The measurement shows that the highest transimpedance of the channel is 50 kΩ, the uncompensated walk error is 1.44 ns in a wide linear dynamic range of 66 dB （1 ： 2000）, and the input referred noise current is 2.3 pa/√ （rms）, resulting in a very low detectable input current of 1μA with SNR = 5.

关键词： laser radar linear dynamic range transimpedance amplifier timing comparator walk error

Intra-Annual Variability of Diurnal Cycle Precipitation over China from 1960–2000

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Atmospheric and Oceanic Science Letters 2013年第6期6卷 451-456页

作者： LIU Liang-Yu ma Zhu-Guo Key Laboratory of Regional Climate-Environment in Temperate East Asia Institute of Atmospheric Physics Chinese Academy of Sciences University of Chinese Academy of Sciences

Characteristics of diurnal cycle precipitation over China are investigated using twice-daily observations by the China Meteorological Administration during 1960–2000. Characteristics investigated include nighttime/daytime precipitation amount(pa), intensity, and frequency. Geographically, the region is separated into western and eastern China by the 110°E longitude. Our analysis shows that there generally is more night-time than daytime precipitation in western China, particularly in the Sichuan Basin. Over eastern China, the opposite holds true, particularly along the southeast coast. Regional average monthly daytime and night-time precipitation peaks in the same month for both western and eastern China. Over western China, monthly night-time precipitation is always greater than that during daytime, but the night-time precipitation frequency(PF) is only greater in non-summer(June–August) months. Over eastern China, daytime precipitation is greater than that in the night-time during the warm season(may–August) in both amount and frequency. The night-day difference(night-time minus daytime) in pa over western China is mainly influenced by precipitation intensity, while over eastern China the night-day difference in rainfall amount is mostly driven by PF.

关键词： precipitation frequency precipitation intensity night-time precipitation daytime precipitation

Atrypid Brachiopods from the Upper Devonian Wangchengpo Formation(Frasnian)of southern Guizhou,China—Extinction patterns in the Frasnian of South China

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Acta Geologica Sinica(English Edition) 2005年第4期79卷 437-452页

作者： ma Xueping paul COPPER SUN Yuanlin LIAO Weihua The Key Laboratory of Orogenic Belts and Crustal Evolution Department of Geology Peking University Beijing 100871 China Department of Earth Sciences. Laurentian University Sudbury Canada P3E 2C6 Nanjing Institute of Geology and palaeontology Chinese Academy of Sciences Nanjing Jiangsu 210008 China

The Wangchengpo Frasnian section of Dushan County contains two atrypid brachiopod assemblages. The lower is characterized by the Atryparia （Costatrypa） dushanensis fauna that appears at the base of the Hejiazhai Member approximately in the falsiovalis to transitans conodont zones： the upper is characterized by the Radiatrypa yangi fauna, which appears in the Lujiazhai Member approximately correspondent with the hassi to Upper rhenana conodont zones. Atrypid brachiopods, together with other brachiopods from the Dushan section show that the Hejiazhai Member is of Frasnian age. Preliminary analyses of Frasnian atrypid brachiopods from sections of South China indicate that there are nine genera and subgenera including Atryparia （Costatrypa）, Kyrtatrypa, Spinatrypa, lsospinatrypa, Spinatrypina, lowatrypa, Desquamatia （Desquamatia）. Desquamatia （Seratrypa）, and Radiatr）pa. Atrypid species diversity did not change much through the Frasnian. On a regional scale in South China, most atrypid species went extinct prior to the Frasnian/Famennian boundary. At any specific locality or section, these atrypids became extinct about 20-40 m below the Frasnian/Famennian （F/F） boundary, within the linguiformis conodont Zone, marking this as the major extinction level. Three new atrypid species are described： Atryparia （Costatrypa） dushanensis, lowatrypa pseudobodini, and Radiatrypa yangi.

关键词： Atrypids Brachiopoda Upper Devonian Wangchengpo Formation South China

Nicotine from cigarette smoking and diet and parkinson disease:a review

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Translational Neurodegeneration 2017年第1期6卷 174-180页

作者： Chaoran ma Yesong Liu Samantha Neumann Xiang Gao Department of Nutritional Sciences The Pennsylvania State UniversityUniversity ParkUniversity ParkPAUSA Department of Neurology Kailuan General HospitalTangshanChina Eberly College of Science The Pennsylvania State UniversityUniversity ParkUniversity ParkPAUSA

Evidence from epidemiological studies suggest a relationship between cigarette smoking and low risk of parkinson disease(PD).As a major component of tobacco smoke,nicotine has been proposed to be a substance for preventing against PD risk,with a key role in regulating striatal activity and behaviors mediated through the dopaminergic *** studies also showed that nicotine could modulate dopamine transmission and reduce levodopa-induced ***,previous clinical trials yield controversial results regarding nicotine *** this review,we updated epidemiological,preclinical and clinical data,and studies on nicotine from *** also reviewed interactions between genetic factors and cigarette *** a small amount of nicotine can saturate a substantial portion of nicotine receptors in the brain,nicotine from other sources,such as diet,could be a promising therapeutic substance for protection against PD.

关键词： Nicotine Smoking Diet Gene-environment interactions parkinson disease

Temporal and Spatial Distribution of the Late Devonian (Famennian) Strata in the Northwestern Border of the Junggar Basin, Xinjiang, Northwestern China

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Acta Geologica Sinica(English Edition) 2017年第4期91卷 1413-1437页

作者： ma Xueping ZHANG Meiqiong ZONG Pu ZHANG Yubo Lü Dan The Key Laboratory of Orogenic Belts and Crustal Evolution School of Earth and Space Sciences Peking University Beijing 100871 China Institute of Geology Chinese Academy of Geological Sciences Beijing 100037 China

The base of the Saerba Member （Mbr） of the Hongguleleng Formation （Fm.） probably lies in the Famennian palmatolepis crepida Zone; the Longkou Mbr is probably a sedimentary wedge that thins out northwards; the Duguer Mbr has an approximate age from the upper part of the pa. marginifera Zone or the Lower pa. rugosa trachytera Zone through the top of the pa. perlobata postera Zone; the Wulan Mbr has an age approximately corresponding to the whole pa. gracilis expansa Zone. In the Bulongguoer section, the Lower Mbr of the Hongguleleng Fro. corresponds to Famennian pa. crepida Zone through pa. marginifera Zone; the Middle Mbr probably ranges from the pa. r. trachytera Zone through the pa. g. expansa Zone. The basal Namu Mbr of the Heishantou Fm. is probably the product during and after the Hangenberg Event in the upper part of the Siphonodellapraesulcata Zone, which is still within the Devonian. In this context, the underlying Chasi Mbr may approximately correspond to the lower part of the S. praesulcata Zone （before the Hangenberg Event）. Lateral distribution of strata indicates that the Upper Devonian in the Gennaren and Saerba areas each constitutes a structure of syncline, which differs from the previous recognition of a monocline structure.

关键词： Junggar Bulongguoer Hongguleleng Formation Heishantou Formation "Hebukehe"Formation Xinjiang

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脂肪替代物在肉制品加工中应用的研究进展

食品工业科技 2025年第2期46卷 367-374页

作者：许皖田许玉娟李聪周辉马相杰徐宝才合肥工业大学食品与生物工程学院合肥工业大学农产品生物化工教育部工程研究中心河南双汇投资发展股份有限公司

脂肪可以为人体提供必要的能量，在肉制品加工过程中起到改善感官品质的作用，但过多摄入脂肪可能导致肥胖、心血管疾病等健康问题。随着人们食品安全和健康意识的提高，低脂肉制品受到广大消费者的追捧。近年来，脂肪替代物成为当前肉... 详细信息

脂肪可以为人体提供必要的能量，在肉制品加工过程中起到改善感官品质的作用，但过多摄入脂肪可能导致肥胖、心血管疾病等健康问题。随着人们食品安全和健康意识的提高，低脂肉制品受到广大消费者的追捧。近年来，脂肪替代物成为当前肉制品低脂化加工的研究热点之一。膳食纤维、预乳液、蛋白质基质等传统脂肪替代物无法完全模拟脂肪的口感，会导致肉制品感官品质下降，油凝胶与乳液凝胶等新型脂肪替代物通过对油脂进行改良，能够更好地模拟动物脂肪的口感，但人们对其接受度较低。目前，脂肪替代物主要应用于法兰克福香肠及汉堡肉饼等西式肉制品中，在中式肉制品中的研究较少。本文预测有关脂肪替代物的研究将会从新型脂肪替代物的研发、功能性因子的添加以及脂肪替代物在人体内的消化吸收等角度开展，旨在为提高新型减脂肉制品的食用品质提供思路和技术支持。

关键词：低脂肉制品脂肪替代物油凝胶乳液凝胶

来源：博看期刊

Analysis of the Arabidopsis Floral Proteome:Detection of over 2000 Proteins and Evidence for Posttranslational Modifications

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Journal of Integrative Plant Biology 2009年第2期51卷 207-223页

作者： Baomin Feng Lianchao Li Xiaofan Zhou Bruce Stanley Hong ma Department of Biology the Pennsylvania State University University Park PA 16802 USA proteomics and mass Spectrometry Core Facility 003 Althouse Laboratory the Pennsylvania State University University Park PA 16802 USA The Intercollege Graduate Program in Cell and Developmental Biology the Huck Institutes of the Life Sciences the Pennsylvania State University University Park PA 16802 USA Section of Research Resources H093 the College of Medicine the Pennsylvania State University Hershey PA 17033 USA

The proteome of the Arabidopsis flower has not been extensively studied previously. Here, we report a proteomic analysis of the wild type Arabidopsis flower. Using both two-dimensional electrophoresis/mass spectrometry （2-DGEIMS） and multi-dimensional protein identification technology （MudPIT） approaches, we identified 2 446 proteins. Although a single experiment or analysis uncovered only a subset of the proteins we identified, a combination of multiple experiments and analyses facilitated the detection of a greater number of proteins. When proteins are grouped according to RNA expression levels revealed by microarray experiments, we found that proteins encoded by genes with relatively high levels of expression were detected with greater frequencies. On the other hand, at the level of the individual gene/protein, there was not a good correlation between protein spot intensity and microarray values. We also obtained strong evidence for post-translational modification from 2-DGE and MudPIT data. We detected proteins that are annotated to function in protein synthesis, folding, modification, and degradation, as well as the presence of regulatory proteins such as transcription factors and protein kinases. Finally, sequence and evolutionary analysis of genes for active methyl group metabolisms suggests that these genes are highly conserved. Our results allow the formulation of hypotheses regarding post-translational regulation of proteins in the flower, providing new understanding about Arabidopsis flower development and physiology.

关键词： Arabidopsis floral methylation multi-dimensional protein identification technology protein modification proteome.

Key characterization factors of accurate power modeling for Fin FET circuits

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Science China(Information Sciences) 2015年第2期58卷 182-194页

作者： ma KaiSheng CUI XiaoXin LIAO Kai LIAO Nan WU Di YU DunShan Institution of Microelectronics Peking University Department of Computer Science and Engineering The Pennsylvania State UniversityUniversity ParkPA 16801 USA

Due to its excellent device features, manufacture process compatibility and diversity of the circuit structures, The Fin FET is considered appropriate candidate for the conventional bulk-MOSFET in sub-22 nm technology nodes. However, the power estimation CAD tools for Fin FET are missing at the moment, which mainly results from the absence of Fin FET power analysis and Fin FET power model. Three key factors for Fin FET power model are: the dimension of the look-up-tables, that to find out the most significant factors that influence Fin FET power and to make them as indexes for the look-up-tables; the distance between sampling points; and the interpolation method. In this paper, various factors that may contribute to the Fin FET power consumption are evaluated. Of all the factors, the continuous ones are compared with sensitivity method. As to other discrete factors, methods of building them in power model are given according to the features of the each factor and the way it influences the power. Based on the simulation result, standard cell power library model for Fin FET is proposed. The research work lays foundation for accurate power analysis and modeling for high-level power analysis of Fin FET circuits. Besides, these key factors are also crucial for low-power Fin FET circuit design.

关键词： Fin FET power modeling leakage power internal power input slew output load