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Sea Cucumber Fishery in Aurora, Philippines

Open Journal of Ecology 2024年第2期14卷 101-113页

作者： Maria Cristina B. cañada Michelle A. Resueño Eusebio V. Angara Department of Forestry and Environmental Sciences Aurora State College of Technology Baler Aurora Philippines

This study was conducted to provide a preliminary assessment of the sea cucumber fishery in Aurora, Philippines. This was conducted from February to June 2013. All sea cucumber gatherers and traders, obtained through snowball sampling, in each identified sea cucumber fishery area in six coastal municipalities (Baler, Dipaculao, Dinalungan, casiguran, Dilasag and Dingalan) were interviewed using a structured interview schedule and focused group discussions (FGD). Results revealed that gathering sea cucumbers were accomplished by handpicking, skin diving or compressor diving. A total of 15 commercial species were regularly gathered. Out of this, three species are of very high economic value (≥Php 4000/kg) (Holothuria nobilis, Holothuria scabra, and Actinopyga lecanora). The average number of kilograms harvested per hour per trip ranges from 0.21 (Holothuria fuscopunctata) to 2.71 (Holothuria scabra), while the average size of commonly gathered sea cucumber varies among species with Holothuria lecanora showed an average length (29.26 cm) greater than recorded 24 cm. Processing mainly involves washing, slicing, boiling, drying and packing. Processed sea cucumbers or trepan were sold to middlemen or direct buyers who usually offered higher prices (36.36% up to 69.20%) than the former. Problems encountered by sea cucumber gatherers and traders include a decline in total catch, a shift in area of collection from intertidal zones to deeper waters, an increase in the number of hours spent in finding and gathering sea cucumbers, the use of compressors in gathering, the decline of larger species and gathering of smaller sizes in huge amount, the absence of conservation program for sea cucumber, and the lenient implementation of government policies with regards to coastal resources management.

关键词： Assessment Sea Cucumber Trepang Fishery

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Metabolic reprogramming by Syntenin-1 directs RA FLS and endothelial cell-mediated inflammation and angiogenesis

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Cellular & Molecular Immunology 2024年第1期21卷 33-46页

作者： Anja meyer Stephanie R.Zack Wes Nijim Adel Burgos Vishwa patel Brian Zanotti Michael V.Volin M.Asif Amin Myles J.Lewis Costantino Pitzalis Shiva Arami Joseph A.Karam Nadera J.Sweiss Shiva Shahrara Jesse Brown VA Medical Center ChicagoILUSA Department of Medicine Division of RheumatologyThe University of Illinois at ChicagoChicagoILUSA Department of Microbiology and Immunology Midwestern UniversityDowners GroveILUSA Division of Rheumatology and Clinical Autoimmunity Center of Excellence University of MichiganAnn ArborMIUSA Centre for Experimental Medicine and Rheumatology William Harvey Research InstituteBarts and The London School of Medicine and DentistryQueen Mary University of LondonLondonUnited Kingdom Centre for Experimental Medicine&Rheumatology William Harvey Research InstituteQueen Mary University of London and Barts NIHR BRC&NHS TrustLondonUK Department of Biomedical Sciences Humanitas Universityand Humanitas Research HospitalMilanItaly Department of Orthopedic Surgery the University of Illinois at ChicagoChicagoILUSA

A novel rheumatoid arthritis(RA)synovial fluid protein,Syntenin-1,and its receptor,Syndecan-1(SDC-1),are colocalized on RA synovial tissue endothelial cells and fibroblast-like synoviocytes(FLS).Syntenin-1 exacerbates the inflammatory landscape of endothelial cells and RA FLS by upregulating transcription of IRF1/5/7/9,IL-1β,IL-6,and CCL2 through SDC-1 ligation and HIF1α,or mTOR ***,Syntenin-1 orchestrates RA FLS and endothelial cell invasion via SDC-1 and/or mTOR *** Syntenin-1 reprogrammed endothelial cells,the dynamic expression of metabolic intermediates coincides with escalated glycolysis along with unchanged oxidative factors,AMPK,PGC-1α,citrate,and inactive oxidative ***,RA FLS rewired by Syntenin-1 displayed a modest glycolytic-ATP accompanied by a robust mitochondrial-ATP *** enriched mitochondrial-ATP detected in Syntenin-1 reprogrammed RA FLS was coupled with mitochondrial fusion and fission recapitulated by escalated Mitofusin-2 and DRP1 *** found that VEGFR1/2 and Notch1 networks are responsible for the crosstalk between Syntenin-1 rewired endothelial cells and RA FLS,which are also represented in RA *** to RA explants,morphological and transcriptome studies authenticated the importance of VEGFR1/2,Notch1,RAPTOR,and HIF1αpathways in Syntenin-1 arthritic mice and their obstruction in SDC-1 deficient ***,dysregulation of SDC-1,mTOR,and HIF1αnegated Syntenin-1 inflammatory phenotype in RA explants,while inhibition of HIF1αimpaired synovial angiogenic imprint amplified by *** conclusion,since the current therapies are ineffective on Syntenin-1 and SDC-1 expression in RA synovial tissue and blood,targeting this pathway and its interconnected metabolic intermediates may provide a novel therapeutic strategy.

关键词： Syntenin-1 Syndecan-1 RA FLS RA explants immunometabolism

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Efficient and reversible separation of NH_(3) by deep eutectic solvents with multiple active sites and low viscosities

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Chinese Journal of Chemical Engineering 2024年第3期67卷 97-105页

作者： Jiayin Zhang Lu Zheng Siqi Fang Hongwei Zhang Zhenping cai Kuan Huang Lilong Jiang National Engineering Research Center of Chemical Fertilizer catalyst(NERC-CFC) College of Chemical EngineeringFuzhou UniversityFuzhou 350002China Qingyuan Innovation Laboratory Quanzhou 362801China

The efficient separation and collection of ammonia(NH_(3))during NH_(3) synthesis process is essential to improve the economic efficiency and protect the *** this work,ethanolammonium hydrochloride(EtOHACl)and phenol(PhOH)were used to prepare a novel class of deep eutectic solvents(DESs)with multiple active sites and low *** NH_(3) separation performance of EtOHACl+PhOH DESs was analyzed *** is figured out that the NH_(3) absorption rates in EtOHACl+PhOH DESs are very *** NH_(3) absorption capacities are very high and reach up to 5.52 and 10.74 mol·kg1 at 11.2 and 100.4 kpa under 298.2 K,*** addition,the EtOHACl+PhOH DESs present highly selective absorption of NH_(3) over N_(2) and H_(2) and good regenerative properties after seven cycles of absorption/*** intrinsic separation mechanism of NH_(3) by EtOHACl+PhOH DESs was further revealed by spectroscopic analysis and quantum chemistry calculations.

关键词： Separation Absorption Ionic liquid Deep eutectic solvent Multiple active site Low viscosity

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乐活健康

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空中英语教室（高级版．彭蒙惠英语） 2024年第1期 10-11,39,40页

作者： patrick McCreless John meyer 不详

03一名医生从自己的中风体验中学到的三件事或许能拯救你的生命当朱利安·金医生正在示范一个小型外科手术时,他走路开始出现异常。他自己没有注意到,但手术室里有人注意到了“当时我脑出血了……和高血压有关,”金医生说,“我甚至不知... 详细信息

03一名医生从自己的中风体验中学到的三件事或许能拯救你的生命当朱利安·金医生正在示范一个小型外科手术时,他走路开始出现异常。他自己没有注意到,但手术室里有人注意到了“当时我脑出血了……和高血压有关,”金医生说,“我甚至不知道我有高血压。”

关键词：外科手术高血压手术室脑出血医生朱利安

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高校竞技健美操运动员落地偏侧性和稳定性的生物力学研究

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中国运动医学杂志 2024年第4期43卷 266-274页

作者：王莉莉 Wan Ahmad Munsif Bin Wan pa 王宇轩李风雷颉梦宁许春莲马来西亚国立大学教育学院吉隆坡43600 东华理工大学体育学院南昌330032 南昌交通学院体育学院南昌330100

目的:分析竞技健美操运动员落地动作的生物力学特征,比较优势侧和非优势侧生物力学指标的偏侧性,探究影响落地稳定性的关键偏侧性因素。方法:以26名高校女性健美操运动员为研究对象,同步采集40 cm高台垂直双脚落地动作中的下肢运动学和... 详细信息

目的:分析竞技健美操运动员落地动作的生物力学特征,比较优势侧和非优势侧生物力学指标的偏侧性,探究影响落地稳定性的关键偏侧性因素。方法:以26名高校女性健美操运动员为研究对象,同步采集40 cm高台垂直双脚落地动作中的下肢运动学和动力学数据,比较优势侧和非优势侧的触地时刻关节角度、关节活动度(ROM)、地面反作用力(GRF)、负载率、压力中心(COP)位移和包络面积的差异,计算对称指数(代表偏侧性),并采用多元逐步回归方法分析指标偏侧性和COP包络面积的关系。结果:与非优势侧相比,优势侧在触地时刻具有更大的膝外旋和髋外展角(P<0.05),在落地过程中具有较大的踝屈伸、髋屈伸、髋内收-外展及较小的踝旋转ROM(P<0.05);优势侧的伸膝力矩峰值大于非优势侧(P<0.01);垂直方向负载率和伸膝力矩峰值的对称指数与COP包络面积呈显著正相关(P<0.05);垂直方向负载率、伸膝力矩峰值和膝关节旋转角度的对称指数可以解释COP包络面积差异的83.6%。结论:竞技健美操运动员落地动作存在肢体间的偏侧性,垂直方向负载率和伸膝力矩峰值的偏侧性越大,则落地稳定性越差。此外,垂直方向负载率、伸膝力矩峰值和膝关节旋转角度的对称指数可以作为落地稳定性的预测因子。

关键词：健美操落地生物力学偏侧性稳定性

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Risk Assessment of an Environmental Liability in the Commercialization of Hydrocarbons-A Secondary Publication

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Journal of World Architecture 2024年第2期8卷 108-117页

作者： Yamila Navarro Sosa Josécarlos Rojas Acosta Lester Rivas Trasancos carlos C.cañete Pérez Yuletsis Díaz Rodríguez Center for Petroleum Research(CEINPET) HavanaCuba Technological University of Havana JoséAntonio Echeverría HavanaCuba

The risk analysis evaluates the probability of occurrence with the impact of said *** the hydrocarbon sector,an environmental liability is an improperly abandoned facility,soil contaminated by spills or *** objective of this work is to define a risk management *** characterization of the residue and the area was carried *** events were identified:overflow spill,soil contamination by infiltration,as well as radiant heat and suffocating and toxic fumes from a *** matrix method was applied considering the probability of occurrence against *** danger of infiltration implied a high level of *** risk management plan was drawn up,its main action being the liquidation of the pool and the sanitation of the area.

关键词： Hazardous events Environmental liability Waste Risk Vulnerability

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翻译在藏传佛教中国化进程中的重要作用

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攀登（藏文版） 2024年第2期 148-155页

作者：交巴草中国民族语文翻译中心(局)

佛教通过翻译在传入吐蕃过程中,汲取了苯教的部分教义,形成了具有藏族文化特色的藏传佛教。藏传佛教在迅速发展过程中推崇佛经翻译事业起到了重要的推动作用。新时代时期,积极推进藏传佛教中国化是藏传佛教健康传承的必经之路。在坚持... 详细信息

佛教通过翻译在传入吐蕃过程中,汲取了苯教的部分教义,形成了具有藏族文化特色的藏传佛教。藏传佛教在迅速发展过程中推崇佛经翻译事业起到了重要的推动作用。新时代时期,积极推进藏传佛教中国化是藏传佛教健康传承的必经之路。在坚持藏传佛教中国化方向进程中,加强汉藏翻译,一方面使藏传佛教教义教规的翻译呈现社会主义发展内涵,适应社会主义社会的时代要求。另一方面引进宗教中国化的理论,以社会主义核心价值观为引领,使藏传佛教浸润中国特色,弘扬先进思想。

关键词：翻译藏传佛教新时代中国化

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MLMT与MLST在新生隐球菌基因分型中的应用研究

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贵州医科大学学报 2024年第1期49卷 84-89页

作者：朱键曹佳非康颖倩三上襄 Wieland meyer 贵阳市第二人民医院&贵州医科大学附属金阳医院消化内科贵州贵阳550081 贵州医科大学附属医院消化内科贵州贵阳550004 贵州医科大学研究生院贵州贵阳550004 千葉大学医学真菌研究中心日本千葉县260-8673 悉尼大学Westmead医学研究所澳大利亚悉尼NSW2145

目的探讨多位点微卫星灶分型(MLMT)和多位点序列分型(MLST)在新生隐球菌(***)基因分型中的应用。方法提取22株来源于国内及日本已明确为新生隐球菌的菌株DNA,经MLMT及MLST相应位点的引物进行扩增、测序;计算各微卫星灶(CNG1、CNG2及CN... 详细信息

目的探讨多位点微卫星灶分型(MLMT)和多位点序列分型(MLST)在新生隐球菌(***)基因分型中的应用。方法提取22株来源于国内及日本已明确为新生隐球菌的菌株DNA,经MLMT及MLST相应位点的引物进行扩增、测序;计算各微卫星灶(CNG1、CNG2及CNG3)序列中简单重复序列的重复数,确定菌株MLMT的基因型;将本研究菌株的MLST中各位点序列和网上数据库相应序列进行对比,获取该菌株的MLST基因型;比较两种方法在分型中分辨能力。结果在22株菌中,有16株的基因型为MLMT17/MLST5(16/22,72.73%),MLMT将所有菌株分为7型,而MLST分为4型;根据MLST分型,MLMT17、16、34及39的菌株为MLST5;MLMT2、14、29相对应MLST66、32及31;两种方法的分型分辨能力比较,差异无统计学意义(P=0.488)。结论 MLMT-17/MLST 5是我国和日本的新生隐球菌常见基因型,包含CNG1、CNG2及CNG3位点的MLMT可作为MLST的替代或补充。

关键词：新生隐球菌多位点微卫星灶分型多位点序列分型

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Design of Slant-Form Tool in Precision Reuse of Digital paper Display

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Journal of Materials Science & Technology 2011年第9期27卷 846-850页

作者： pai-Shan pa Department of Digital Content Design Graduate School of Toy and Game Design National Taipei University of Education Taipei 10667 Taiwan China

A reuse fabrication module using micro electroetching as a precision machining process with a new design of a slant-form tool to remove the defective indium-tin-oxide （ITO） nanostructure from the optical polyethyleneterephthalate （PET） surfaces of digital paper display is presented in current studies. The low yield of ITO thin film deposition is an important factor in optoelectronic semiconductor production. The adopted precision reuse process requires only a short period of time to remove the ITO nanostructure easily and cleanly, which is based on technical and economical considerations and is highly efficient. In the current experiment, a large inclined angle of the cathode and a small end radius of the anode take less time for the same amount of ITO removal. A higher feed rate of the optical PET diaphragm combines with enough electric power to drive fast micro electroetching. A small rotational diameter of the anode accompanied by a small width of the cathode corresponds to a higher removal rate for the ITO nanostructure. A pulsed direct current can improve the effect of dreg discharge and is advantageous to couple this current with the fast feed rate of the workpiece. This improvement is associated with an increase in current rating. High rotational speed of the slant-form tool can improve the effect of dregs discharge and is advantageous to associate with the fast feed rate of the workpiece （optical PET diaphragm）.

关键词： Reuse fabrication Slant-Form Digital paper display Optical polyethyleneterephthalate (PET) diaphragm Indium-tin-oxide (ITO) nanostructure Micro electroetching

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particle elasticity influences polymeric artificial antigen presenting cell effectiveness in vivo via CD8+T cell activation,macrophage uptake,and the protein corona

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Nano Research 2024年第10期17卷 9052-9064页

作者： Savannah E.Est-Witte Sydney R.Shannon Dennis H.Gong Kaitlyn G.calabresi Jawaun J.Harris Kaitlyn Storm Edwin J.Yoo Ariel Isser Vivek P.Jani Natalie K.Livingston Mary O.Omotoso Kelly Rhodes Elana Ben-Akiva Randall A.meyer Zoe T.Hsieh Simone Sidoli Stephany Y.Tzeng Jonathan P.Schneck Jordan J.Green Translational Tissue Engineering Center Institute for NanobiotechnologyDepartment of Biomedical EngineeringJohns Hopkins School of Medicine400 N BroadwayBaltimoreMD 21231USA Institute for Cell Engineering Department of PathologyJohns Hopkins School of Medicine733 N BroadwayBaltimoreMD 21205USA Department of Biochemistry Albert Einstein College of MedicineThe BronxNew York CityNY 10461USA

Adoptive cell therapy(ACT)is an immunotherapy strategy for cancer that has seen widespread clinical *** ACT,patient-derived lymphocytes are stimulated with the antigen of interest ex vivo,proliferated,then returned to the patient to initiate an antigen-specific antitumor *** effective,this process is resource-intensive and logistically impossible for many *** artificial antigen presenting cells(aAPCs)offer a potential“off-the-shelf”alternative to ex vivo *** particulate aAPCs perform well in vitro,they have had limited success in vivo due to poor bioavailability after *** to bioavailability include rapid clearance,unfavorable biodistribution,and inadequate interactions with CD8+T cells at sites of *** properties such as elasticity have been shown to vastly impact the bioavailability and particle-cell interactions,but this has yet to be investigated in the context of aAPCs for in vivo T-cell *** literature likewise indicates that biomaterial properties,especially elasticity,can modulate T-cell activation in *** the goal of creating a more biomimetic,next-generation particulate aAPC,we developed a poly(ethylene)glycol hydrogel particle platform with tunable elasticity to investigate the impact of elasticity on antigen-specific T cell activation for in vivo adoptive *** this knowledge,we were able to gain more precise control over in vivo T cell activation and investigate possible mechanisms including the effects of aAPC elasticity on T cell binding,macrophage uptake,and the protein corona.

关键词： adoptive cell therapy artificial antigen presenting cells particle drug delivery elasticity protein corona poly(ethylene glycol)

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