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Correlates of resistance to gastrointestinal nematode infection in Nigerian West African dwarf sheep

Asian pa.ific Journal of Tropical Medicine 2012年第7期5卷 529-532页

作者： IK Idika SN Chiejina LI Mhomga pa.Nnadi la Ngongeh Depa.tment of Veterinary pa.asitology and Entomology University of NigeriaNsukkaNigeria Depa.tment of Veterinary pa.asitology and Microbiology Michael Okpara University of AgricultureUmudikeNigeria Depa.tment of Animal Health and Production University of AgricultureMakurdiNigeria Depa.tment of Animal Health and Production University of NigeriaNsukkaNigeria

Objective:To investigate correlates of resistance to G1 nematode infection in Nigerian West African dwarf(WAD) ***:Thirty three sheep were randomly assigned to two groups, A(n=27) which were used for experimental infections,and B(n=6) which served as uninfected *** infected animal received weekly escalating infections with infective larvae(60% Haemonchus contortus(***) and 40%Trichostrongylus colubriformis(***) for 4 *** responses of all the infected and control sheep were assessed by faecal egg count(FEC),worm burden(Wb),pa.ked cell volume(PCV),body weight(Bwt).and body condition score(BCS).On the basis of their individual faecal egg output,lambs in group A with epg≤1 000 on any sampling day were classified as low faecal egg count(LFEC) phenotype(n = 16),those with epg between 1 000 and 10 000 as intermediate(n=5) and lambs with epg > 10 000 as high feacal egg count(HFEC) phenotype(n=6).Results:The difference between the FEC classes was highly significant(P=0.001).The BCS and weight gained at the end of the experiment by the control and LFEC sheep was significandy higher(P≤0.05) than those of the intermediate and HFEC *** was a significant and negative correlation between the pa.asitological measures and the trio of BCS,PCV and Bwt of ***:The result of the study indicated that the FEC,weight gain,PCV,and BCS are correlates and potential selection crileria of G1 nematode resistant WAD sheep.

关键词： WAD sheep Phenotypic markers Resistance Resilience GI nematode

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Multi-detector computed tomography evaluation of tracheobronchial anomaly in pediatric pa.ients with left pulmonary artery sling

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Chinese Medical Journal 2013年第14期126卷 2790-2792页

作者： HU Xi-hong pa.Mi-er SHEN Quan-li HUANG Guo-ying Depa.tment of Radiology Children's Hospital of Fudan University Shanghai 201102 China Heart Centre Children's Hospital of Fudan University Shanghai 201102 China

The left pulmonary artery sling （Lpa.） is a rare vascular anomaly causing respiratory distress in which theleft pulmonary artery arises from the posterior aspect of the right pulmonary artery, courses posteriorly to the right of the bronchus and pa.ses between the trachea and oesophagus to reach the hilum of the left lung. The Lpa. is frequently associated with tracheobronchial tree anomalies and congenital cardiac defects. Proper assessment of the tracheobronchial and cardiovascular anomaly is essential in Lpa. for planning management of the pa.ient. Currently,

关键词： left pulmonary artery sling tracheobronchial stenosis multi-detector, computed tomography

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Numerical analysis of supersonic jet flow and dust transport induced by air ingress in a fusion reactor

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Nuclear Science and Techniques 2021年第7期32卷 72-82页

作者： Bu-er Wang Shi-Chao Zhang Zhen Wang Jiang-Tao Jia Zhi-Bin Chen Institute of Nuclear Energy Safety Technology Hefei Institutes of Physical ScienceChinese Academy of SciencesHefei 230031China University of Science and Technology of China Hefei 230026China

During a loss of vacuum accident(LOVA),the air ingress into a vacuum vessel(VV)may lead to radioactive dust resuspension,migration,and even explosion,thereby posing a great threat to the safe operation of future fusion reactors;thus,it is crucial to understand the flow characteristics and radioactive dust transport behavior induced by ***,only a few studies have identified the characteristics of the highly under-expa.ded jet flow at a scale of milliseconds during ***,the occurrence and behavior of a Mach disk is yet to be captured in existing *** this study,we used a more advanced model with a finer mesh and adaptive mesh strategies to capture the Mach disk in a VV during *** detail,a computational fluid dynamics–discrete phase model one-way coupled multiphase approach was established using the computational fluid dynamics code ANSYS FLUENT and applied to the analysis during the first seconds of *** results showed that air ingress into the VV behaved like a highly free under-expa.ded jet at the initial stage and Mach disk was formed at~6 ***,the flow field dramatically changed at the position of the Mach *** jet core before the Mach disk had a maximum velocity of~8 Mach with the corresponding lowest static pressure(~100 pa.and temperature(few tens of K).The friction velocities in the lower pa.t of the VV,which is an area of concern due to dust deposition,were generally larger than 15 m/s near the inlet ***,the crude prediction of the pa.ticle trajectories demonstrated the spiral trajectories of the dust following the air ***,this study provided a basis for further safety analysis and accident prevention related to dust transport and explosion in future fusion reactors.

关键词： Supersonic jet Radioactive dust Loss of vacuum accident Mach disk Friction velocity

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新生儿期Sturge-Weber综合征一例

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中华儿科杂志 2005年第5期43卷 398-399页

作者：朱珍帕米尔耿道颖复旦大学附属儿科医院放射科上海200032 复旦大学附属华山医院放射科

患儿男,25天.孕40周+1,出生体重3800 g,因第二产程延长剖腹产.2003年12月15日入院,入院前约3 h突然出现抽搐,两眼凝视,右上肢、右下肢及右侧口角、眼角抽动约持续10 min,反复发作,以右上肢、右下肢强直抽动为主要表现,无发热、腹泻、呕... 详细信息

患儿男,25天.孕40周+1,出生体重3800 g,因第二产程延长剖腹产.2003年12月15日入院,入院前约3 h突然出现抽搐,两眼凝视,右上肢、右下肢及右侧口角、眼角抽动约持续10 min,反复发作,以右上肢、右下肢强直抽动为主要表现,无发热、腹泻、呕吐.发作期间神志、反应尚好,哭声响,吸吮佳,大小便正常.体格检查:左侧颜面部及左下肢、躯干散在大片状血管瘤.眼科检查示左眼继发性青光眼.双侧肢体等长、等粗.B超:肝、肾、脾、腹腔内未见明显异常.……

关键词： Weber综合征新生儿期第二产程延长继发性青光眼 2003年出生体重反复发作主要表现下肢强直发作期间体格检查眼科检查右上肢剖腹产入院前右下肢大小便左下肢颜面部血管瘤抽动

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Identification of <i>JAK2</i>(V617F) Mutation in Myeloproliferative Neoplasms by Using Allele Specific Polymerase Chain Reaction (AS-PCR)

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American Journal of Molecular Biology 2020年第4期10卷 273-282页

作者： Khin la Pyae Tun Aung Zaw latt Win pa.pa.Naing San San Htwe Yamin Ko Ko Win Win Mar San Yu Hlaing Wai Wai Han Sein Win Depa.tment of Medical Research Yangon Myanmar Depa.tment of Clinical Haematology Yangon General Hospital Ministry of Health and Sports Nay Pyi Taw Myanmar

Myeloproliferative neoplasms (MPNs) are a group of clonal haematopoietic stem cell disorders characterized by the proliferation of one or more myeloid cell lineages. According to WHO classification, the Janus associated kinase 2 (JAK2) V617F mutation is one of the major diagnostic criteria in BCR-ABL1 negative myeloproliferative neoplasms. The aim of this study is to detect the JAK2 (V617F) mutation in pa.ients with myeloproliferative neoplasms to get accurate diagnosis and proper management. A total of 90 clinically diagnosed MPN pa.ients attending to Depa.tment of Clinical Haematology, Yangon General Hospital were enrolled in this study. The mean age was 53.4 ± 14 years which ranged from 16 to 81 years old and male and female ratio was 2.4:1. The identification of JAK2 (V617F) point mutation was found to be positive in 44/90 MPN pa.ients (48.9%). According to MPN subtypes, the JAK2 mutation positivity was found in 19 out of 46 polycythemia vera pa.ients (41.3%), 17 out of 25 essential thrombocythemia pa.ients (68%), 8 out of 15 primary myelofibrosis pa.ients (53.3%), 0 of 4 others myeloproliferative neoplasms (0%). Confirmation of each of nine JAK2 mutation positive and negative samples was done by Sanger sequencing. The arterial or venous thrombotic attack was found in 32/44 JAK2 mutation positive cases (72.7%) and 12/44 JAK2 mutation negative cases (27.3%). The association between thrombotic attack and presence of JAK2 mutation was statistically significance with p = 0.000. The diagnosis of myeloproliferative neoplasms mainly relies on the molecular genetics according to WHO classification. The Allele specific PCR reaction is sensitive, simple test and relatively cost-effective. Therefore, the identification of JAK2 (V617F) somatic point mutation by AS-PCR should be implemented as

关键词： Myeloproliferative Neoplasms JAK2 (V617F) Allele-Specific PCR

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Hepa.itis A vaccine associated with autoimmune hepa.itis

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World Journal of Gastroenterology 2007年第15期13卷 2238-2239页

作者： pa.Berry G Smith-laing Medway Maritime Hospital Windmill Road GillinghamKentUnited Kingdom

To describe a case of probable relapsing autoimmune hepa.itis associated with vaccination against hepa.itis A virus （HAV）. A case report and review of literature were written concerning autoimmune hepa.itis in association with hepa.itis A and other hepa.otropic viruses. Soon a^er the administration of formalin-inactivated hepa.itis A vaccine, a man who had recently recovered from an uncharacterized but self-limiting hepa.itic illness, experienced a severe deterioration （AST 1687 U/L, INR 1.4）. Anti-nuclear antibodies were detectable, and liver biopsy was compa.ible with autoimmune hepa.itis. The observation supports the role of HAV as a trigger of autoimmune hepa.itis. Studies in helper T-cell activity and antibody expression against hepa.ic proteins in the context of hepa.itis A infection are summarized, and the concept of molecular mimicry with regard to other forms of viral hepa.itis and autoimmunity is briefly explored.

关键词： Hepa.itis A virus Vaccine Autoimmune hepa.itis Helper T-cell Molecular mimicry

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Relationship between self-reported residential indoor remodeling and semen quality： a case-control study

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Asian Journal of Andrology 2015年第6期17卷 981-984,I0009,I0010页

作者： Mao-Hua Miao Zheng Li De-Kun Li Bei Yan Hong Liang er-Lei Zhi Hong-Wei Du Wei Yuan Depa.tment of Reproductive Epidemiology and Social Science National Population and Family Planning Key Laboratory of Contraceptive Drugs and Devices ShanghaiI~stitue of Planned Pa[enthood Rese.arch Shanghai China Depa.tment of Urology Shanghai Human Sperm Bank Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai China Division of Reseaich Kaiser Foundation Research Institute Kaiser Permanente Northern California CA USA.

The present study examined the association between residential indoor remodeling and poor semen quality. Sperm donors aged 18-45 years old were recruited in Shanghai, China. Semen specimens were collected and analyzed. An in-person interview was conducted to obtain information on the history of indoor remodeling and potential confounders. A total of 70 pa.ticipa.ts with abnormal semen quality （case group） and 68 controls were examined. A total of 20 subjects reported indoor remodeling in the recent 24 months, and among them 17 subjects reported indoor remodeling in the recent 12 months. Compa.ed with pa.ticipa.ts with no history of indoor remodeling, pa.ticipa.ts with a history of indoor remodeling in the recent 24 months were more than three times as likely to have poor sperm quality （adjusted odds ratio = 3.8, 95% confidence interval： 1.3-12.0） after controlling for potential confounders. The association was strengthened when the analysis was restricted to those who had indoor remodeling in the recent 12 months. Our findings provide preliminary evidence that indoor remodeling has an adverse effect on semen quality.

关键词： case-control study chemicals health effect indoor remodeling semen quality

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Evaluation of the injection and plugging ability of a novel epoxy resin in cement cracks

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Petroleum Science 2024年第2期21卷 1211-1220页

作者： Guang-Yao Leng Wei Yan Hai-Mu Ye er-Dong Yao Ji-Bin Duan Zheng-Xian Xu Ke-Pei Li Jing-Ru Zhang Zhong Li State Key laboratory of Petroleum Resource&Prospecting China University of Petroleum(Beijing)Beijing102249China CNPC Liaohe Oilfield Gas Storage Co.LTD Panjin124000LiaoningChina CNOOC Research Institute Co. Ltd.Beijing100028China

Sustained casing pressure(SCP)is a crucial issue in the oil and gas production *** resins,exhibiting exceptional compressive strength,ductility,and shear bonding strength,have the potential to form reliable *** injectivity and sealing capa.ity of the epoxy resin is crucial pa.ameters for the success of shallow remediation *** study aimed to develop and assess a novel solid-free resin sealant as an alternative to Portland cement for mitigating fluid *** investigation evaluated the viscosity,compressive strength,and brittleness index of the epoxy resin sealant,as well as its tangential and normal shear strengths in conjunction with casing *** flow characteristics and sealing abilities of conventional cement and epoxy resin were compa.atively analyzed in *** results showed that the application of a viscosity reducer facilitated control over the curing time of the epoxy resin,ranging from 1.5 to 6 h,and reduced the initial viscosity from 865.53 to 118.71 m pa.*** mechanical properties of the epoxy resin initially increased with a rise in curing agent content before experiencing a minor *** epoxy resin containing 30%curing agent exhibited optimal mechanical *** a 14-day curing period,the epoxy resin's compressive strength reached81.37 Mpa.2.12 times higher than that of cement,whereas the elastic modulus of cement was 2.99 times greater than that of the epoxy *** brittleness index of epoxy resin is only 3.42,demonstrating high flexibility and *** tangential and normal shear strengths of the epoxy resin exceeded those of cement by 3.17 and 2.82 times,*** a 0.5 mm-wide crack,the injection pressure of the epoxy resin remained below 0.075 Mpa.indicating superior injection and flow ***,the injection pressure of cement surged dramatically to 2.61 Mpa.within 5 *** breakthrough pressure of0.5 PV epoxy resin reached 7.53 Mpa.decreasing the crack's perme

关键词： Sustained casing pressure Epoxy resin sealant Curing agent Viscosity reducer Mechanical properties Crack sealing

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准噶尔盆地复杂地区地层压力预测方法研究及应用

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地球物理学进展 2009年第4期24卷 1377-1383页

作者：帕尔哈提雷德文邵雨中国石油新疆油田分公司勘探开发研究院地球物理研究所乌鲁木齐830011 中国石油新疆油田分公司勘探开发研究院克拉玛依834000

准噶尔盆地地层压力分布复杂,长期以来由于地层压力预测不准,在钻井过程中常出现井壁失稳、卡钻、井壁坍塌、钻井液漏失等工程事故,严重影响了钻井速度.为减少工程复杂问题,准确预测地层压力至关重要.为此,在准噶尔盆地开展了断层相关... 详细信息

准噶尔盆地地层压力分布复杂,长期以来由于地层压力预测不准,在钻井过程中常出现井壁失稳、卡钻、井壁坍塌、钻井液漏失等工程事故,严重影响了钻井速度.为减少工程复杂问题,准确预测地层压力至关重要.为此,在准噶尔盆地开展了断层相关褶皱理论解释复杂构造、利用地质构造建模指导速度建模,求出每层的层速度和真倾角,再用Terzaghi理论计算地层孔隙压力,计算结果证实地层压力预测精度显著提高.

关键词：准噶尔盆地速度模型地质构造模型压力预测静校正

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足月儿早产儿痉挛型脑性瘫痪CT的对比研究

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中国当代儿科杂志 2005年第4期7卷 321-324页

作者：朱珍帕米尔史惟施炳培复旦大学附属儿科医院放射科上海200032 复旦大学附属儿科医院康复科上海200032

目的研究足月儿与早产儿痉挛型脑性瘫痪的CT表现。方法回顾性分析88例痉挛型脑性瘫痪患儿CT表现,分早产儿和足月儿两组分析,其中46例足月儿,42例早产儿。结果88例痉挛型脑性瘫痪患儿CT表现的阳性率78.4%(69/88)。主要是脑室周围白质软化... 详细信息

目的研究足月儿与早产儿痉挛型脑性瘫痪的CT表现。方法回顾性分析88例痉挛型脑性瘫痪患儿CT表现,分早产儿和足月儿两组分析,其中46例足月儿,42例早产儿。结果88例痉挛型脑性瘫痪患儿CT表现的阳性率78.4%(69/88)。主要是脑室周围白质软化(PVL)后遗改变,为47/88例,其中足月儿17例,早产儿30例,两组差异有显著性意义(P<0.05);PVL白质减少可发生于侧脑室体中前部、侧脑室体后部、侧脑室三角区、半卵圆中心,两组间白质减少和侧脑室扩大部位差异无显著性意义;而侧脑室形态不规则扩大在早产儿30例中有7例,足月儿侧脑室扩大未见不规则改变,两组差异有显著性意义(P<0.05)。结论痉挛型脑性瘫痪CT主要表现为PVL后遗改变,早产儿出现PVL和重度PVL的概率明显大于足月儿。

关键词：体层摄影术X线计算机痉挛型脑性瘫痪足月儿早产儿

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