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A review on the chemical speciation and influencing factors of heavy metals in Municipal Solid Waste landfill humus

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Waste Disposal and Sustainable Energy 2024年第2期6卷 209-218页

作者： Qiongyu Sun Bo Sun Defeng Wang Yuyuan pu Mingxiu Zhan Xu Xu Jinqing Wang Wentao Jiao College of Metrology and Measurement Engineering China Jiliang UniversityHangzhou 310018Zhejiang ProvinceChina Zhongke Hualu Soil Remediation Engineering Co. LtdDezhou 253011Shandong ProvinceChina Zhejiang Environmental Protection Group Co. LtdHangzhou 310020Zhejiang ProvinceChina Institute for Thermal Power Engineering Zhejiang UniversityHangzhou 310027Zhejiang ProvinceChina Research Center for Eco-Environmental Sciences Chinese Academy of SciencesHaidian District18 Shuangqing RoadBeijing 100085China

Heavy metal pollution in landfill humus can cause serious environmental problems and may endanger soil ecosystems and human *** biological toxicity of heavy metals is not only related to their total amount but also influenced to a greater extent by the distribution of their chemical *** the different chemical speciation and proportions of heavy metals can provide a more comprehensive and accurate understanding of the pollution characteristics and biological toxic-ity of heavy metals in landfill *** on a review of the relevant literature,this paper systematically summarizes the recent research status of typical heavy metal chemical speciation in landfill *** chemical speciation is diverse and *** instance,heavy metals in residual states and organically bound states have little impact on organisms,while heavy metals in exchangeable states and Fe-Mn oxide states can easily migrate and *** chemical speciation of heavy metals is affected by many factors,among which the soil pH and organic matter content are some of the most important ***,the existing gaps in the current research on the chemical speciation of heavy metals in landfills are described and future research directions are *** work provides a theoretical reference for researching the restoration of heavy metal-contaminated humus soil and the resource utilization of humus soil.

关键词： Landflls Humus soil containing heavy metal-Chemical speciation Distribution characteristics Influencing factors

Chemodivergent Synthesis of Benzofurans and 2,3-Dihydrobenzofurans via Tandem Oxidative Annulation of Enaminones and Salicylaldehydes

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Chinese Journal of Chemistry 2024年第15期42卷 1727-1733页

作者： Xiyan Duan Hui Li Junqi Wang Kun Liu Meixin Shi Weidong Lian Ran Chen pu Liu School of Chemistry&Chemical Engineering Henan University of Science and TechnologyLuoyangHenan 471003China

Chemodivergent synthesis of benzofurans and 2,3-dihydrobenzofurans has been *** a reaction system consisting of DBDMH and K_(2)CO_(3) as promotors,controlled conditions enabled the formation of two sets of valuable heterocycles from the tandem transformation of enaminones and *** key to success was the identification of the reaction parameters,in which the imine intermediate which was formed by transient halogenation coupling and substitution processes underwent either aldol condensation/annulation or imine hydrolysis/aldol *** additives NH_(4)Cl or Fe_(2)(SO_(4))_(3) controlled the unique selectivity of this reaction.A broad substrate scope of enaminones and salicylaldehydes has been employed in this reaction,demonstrating excellent functional group tolerance and versatility.

关键词： Cross-coupling Umpolung Domino reactions Enaminone Benzofurans 2,3-Dihydrobenzofurans

Integrated bulk and single-cell transcriptome data identify clinically relevant cell populations in clear cell renal cell carcinoma

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Genes & Diseases 2024年第1期11卷 42-45页

作者： Pingbao Zhang pu Zhang Jun Gao Xiaosong Li Chengcheng Wei Weihui Liu QingLiu He Yuan Zhang Department of Urology Zhongshan HospitalFudan UniversityShanghai 200032China Department of Urology Surgery Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430022China Department of Liver Surgery and Transplantation Liver Cancer InstituteZhongshan HospitalFudan UniversityShanghai 200032China Clinical Molecular Medicine Testing Center The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Urology The Second Affiliated Hospital of Fujian Medical UniversityQuanzhouFujian 362000China Department of Nephrology Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengduSichuan 610072China

Renal cell carcinoma,which consists of three main histological subtypes,namely,clear cell renal cell carcinoma(ccRCC),papillary RCC(pRCC),and chromophobe RCC(chRCC),accounts for most kidney cancer *** accounts for approximately 85%of all RcC cases,1 and it is a malignant tumor with multiple molecular features and a poor *** have shown that ccRCC is one of the most immune and vaso-invasive cancer types.2 Considering that ccRCC is not sensitive to either radiotherapy or chemotherapy,targeted therapies.

关键词： chemotherapy cancer cases

Atorvastatin ameliorated myocardial fibrosis by inhibiting oxidative stress and modulating macrophage polarization in diabetic cardiomyopathy

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World Journal of Diabetes 2024年第6期15卷 1070-1073页

作者： Xiao-Tian Lei Dan-Lan pu Geng Shan Qi-Nan Wu Department of Endocrinology The First Affiliated Hospital of the Third Military Medical University(Army Medical University)Chongqing 400038China Department of Endocrinology Chongqing Yubei District People's HospitalChongqing 400030China Department of Endocrinology Dazu Hospital of Chongqing Medical UniversityThe People's Hospital of DazuChongqing 402360China

In this editorial,we commented on the article published in the recent issue of the World Journal of *** cardiomyopathy(DCM)is characterized by myocardial fibrosis,ventricular hypertrophy and diastolic dysfunction in diabetic patients,which can cause heart failure and threaten the life of *** pathogenesis of DCM has not been fully clarified,and it may involve oxidative stress,inflammatory stimulation,apoptosis,and *** is lack of effective therapies for DCM in the clinical *** have been widely used in the clinical practice for years mainly to reduce cholesterol and stabilize arterial plaques,and exhibit definite cardiovascular protective *** have shown that statins also have anti-inflammatory and antioxidant *** were particularly concerned about the recent findings that atorvastatin alleviated myocardial fibrosis in db/db mice by regulating the antioxidant stress and antiinflammatory effects of macrophage polarization on diabetic myocardium,and thereby improving DCM.

关键词： Diabetic cardiomyopathy Statins Macrophage Oxidative stress

An Improved CREAM Model Based on DS Evidence Theory and DEMATEL

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Computer Modeling in Engineering & Sciences 2024年第3期138卷 2597-2617页

作者： Zhihui Xu Shuwen Shang Yuntong pu Xiaoyan Su Hong Qian Xiaolei Pan State Key Laboratory of Nuclear Power Safety Monitoring Technology and Equipment Shenzhen518172China School of Automation Engineering Shanghai University of Electric PowerShanghai200090China School of Safety and Management Engineering Hunan Institute of TechnologyHengyang421002China

Cognitive Reliability and Error Analysis Method(CREAM)is widely used in human reliability analysis(HRA).It defines nine common performance conditions(CPCs),which represent the factors thatmay affect human reliability and are used to modify the cognitive failure probability(CFP).However,the levels of CPCs are usually determined by domain experts,whichmay be subjective and ***’smore,the classicCREAMassumes that the CPCs are independent,which is *** the dependence among CPCs will result in repeated calculations of the influence of the CPCs on CFP and lead to unreasonable reliability *** address the issue of uncertain information modeling and processing,this paper introduces evidence theory to evaluate the CPC levels in specific *** address the issue of dependence modeling,the Decision-Making Trial and Evaluation Laboratory(DEMATEL)method is used to process the dependence among CPCs and calculate the relative weights of each CPC,thus modifying the multiplier of the *** detailed process of the proposed method is illustrated in this paper and the CFP estimated by the proposed method is more reasonable.

关键词： Human reliability analysis CREAM uncertainty modeling dependence Dempster-Shafer evidence theory DEMATEL

Using an improved lightweight YOLOv8 model for real-time detection of multi-stage apple fruit in complex orchard environments

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ARTIFICIAL INTELLIGENCE IN AGRICULTURE 2024年第1期11卷 70-82页

作者： Ma, Baoling Hua, Zhixin Wen, Yuchen Deng, Hongxing Zhao, Yongjie pu, Liuru Song, Huaibo Northwest A&F Univ Coll Mech & Elect Engn Yangling 712100 Shaanxi Peoples R China Minist Agr & Rural Affairs Key Lab Agr Internet Things Yangling 712100 Shaanxi Peoples R China Shaanxi Key Lab Agr Informat Percept & Intelligent Yangling 712100 Shaanxi Peoples R China

For the purpose of monitoring apple fruits effectively throughout the entire growth period in smart orchards. A lightweight model named YOLOv8n-ShuffleNetv2-Ghost-SE was proposed. The ShuffleNetv2 basic modules and down-sampling modules were alternately connected, replacing the Backbone of YOLOv8n model. The Ghost modules replaced the Conv modules and the C2fGhost modules replaced the C2f modules in the Neck part of the YOLOv8n. ShuffleNetv2 reduced the memory access cost through channel splitting operations. The Ghost module combined linear and non-linear convolutions to reduce the network computation cost. The Wise-IoU (WIoU) replaced the CIoU for calculating the bounding box regression loss, which dynamically adjusted the anchor box quality threshold and gradient gain allocation strategy, optimizing the size and position of predicted bounding boxes. The Squeeze-and-Excitation (SE) was embedded in the Backbone and Neck part of YOLOv8n to enhance the representation ability of feature maps. The algorithm ensured high precision while having small model size and fast detection speed, which facilitated model migration and deployment. Using 9652 images validated the effectiveness of the model. The YOLOv8n-ShuffleNetv2-Ghost-SE model achieved Precision of 94.1%, Recall of 82.6%, mean Average Precision of 91.4%, model size of 2.6 MB, parameters of 1.18 M, FLOPs of 3.9 G, and detection speed of 39.37 fps. The detection speeds on the Jetson Xavier NX development board were 3.17 fps. Comparisons with advanced models including Faster R-CNN, SSD, YOLOv5s, YOLOv7-tiny, YOLOv8s, YOLOv8n, MobileNetv3_small-Faster, MobileNetv3_small-Ghost, ShuflleNetv2-Faster, ShuflleNetv2-Ghost, ShuflleNetv2-Ghost-CBAM, ShuflleNetv2-Ghost-ECA, and ShuflleNetv2-Ghost-CA demonstrated that the method achieved smaller model and faster detection speed. The research can provide reference for the development of smart devices in apple orchards. (c) 2024 The Authors. publishing services by Elsevier B.V. o

关键词： Multi-stage apple fruit Deep learning Real-time detection Lightweight model MACHINE

Magnetic Fields Reduce Apoptosis by Suppressing Phase Separation of Tau-441

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Research 2024年第1期2023卷 181-197页

作者： Wen-Juan Lin Wen-pu Shi Wan-Yi Ge Liang-Liang Chen Wei-Hong Guo Peng Shang Da-Chuan Yin Key Laboratory for Space Bioscience and Biotechnology School of Life SciencesNorthwestern Polytechnical University127 Youyixi RoadXi'an 710072ShaanxiPR China

The biological effects of magnetic fields(MFs)have been a controversial ***,in recent years,there has been increasing evidence that MFs do affect biological ***,the physical mechanism remains ***,we show that MFs(16 T)reduce apoptosis in cell lines by inhibiting liquid–liquid phase separation(LLPS)of Tau-441,suggesting that the MF effect on LLPS may be one of the mechanisms for understanding the“mysterious”magnetobiological *** LLPS of Tau-441 occurred in the cytoplasm after induction with *** phase-separated droplets of Tau-441 recruited hexokinase(HK),resulting in a decrease in the amount of free HK in the *** cells,HK and Bax compete to bind to the voltage-dependent anion channel(VDAC I)on the mitochondrial membrane.A decrease in the number of free HK molecules increased the chance of Bax binding to VDAC I,leading to increased Bax-mediated *** the presence of a static MF,LLPS was marked inhibited and HK recruitment was reduced,resulting in an increased probability of HK binding to VDAC I and a decreased probability of Bax binding to VDAC I,thus reducing Bax-mediated *** findings revealed a new physical mechanism for understanding magnetobiological effects from the perspective of *** addition,these results show the potential applications of physical environments,such as MFs in this study,in the treatment of LLPS-related diseases.

关键词： inhibited Apoptosis finding

Water molecular activity management towards stable Zn anodes

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Science China Chemistry 2024年

作者： Yun Tan Jun pu Hongpeng Li Dongliang Chao Key Laboratory of Functional Molecular Solids (Ministry of Education) College of Chemistry and Materials Science Anhui Normal University Laboratory of Advanced Materials Fudan University College of Mechanical Engineering Yangzhou University

Zinc-based aqueous batteries(ZABs) have attracted wide interest and become a hot topic in the field of secondary batteries due to their low cost, high safety, and environmental friendliness. However, challenges pertaining to zinc anodes, such as dendrites growth and side reactions, which are associated with the high activity of freedom water molecules in the aqueous electrolyte,significantly hinder the advancement of ZABs. In recent years, strategies aimed at regulating water molecular activity have been demonstrated to address the above issues effectively. Nevertheless, there is a lack of systematic summary regarding the electrolyte engineering and the functional mechanisms for stabilizing zinc anodes from the point of view of water molecular activity management. Hence, this review comprehensively introduces strategies for regulating water activity through the electrolyte engineering to achieve side reaction-suppressed ZABs, including the latest research on aqueous zinc-metal batteries,the origin of critical zinc-related problems, and the development of technological and electrolyte additives. Lastly, various strategies were summarized from different perspectives to improve the performance of zinc metal anodes. This work is expected to present the latest outline and inspire future innovation in electrolyte technologies.

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A Study on Artistic Treatment in Vocal Works

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Journal of Social Science Development Research

Journal of Social Science Development Research 2024年第1期2卷 25-35页

作者： Weiqi pu Geely University of China ChengduChina.

The singing of a vocal work is far more than a simple series of notes,but a delicate artistic process that requires the performer to skillfully use sound,emotion,and *** process is not just about performing music,but also about transmitting emotions,a spiritual dialogue resonating with the *** the wonderful stage of artistic treatment,the performer becomes the second creator of the song,infusing the work with new life through their unique personality and insightful *** the clever concatenation of notes,the performer can unfold the layers of emotion contained within the song,making it richer and deeper.

关键词： Vocal music works Artistic treatment Singing skill