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Fear of covid-19 and emotional dysfunction problems:Intrusive,avoidance and hyperarousal stress as key mediators

World Journal of Psychiatry 2022年第8期12卷 1088-1101页

作者： Raquel Falcó Verónica Vidal-Arenas Jordi Ortet-Walker Juan C Marzo JoséA Piqueras psico-recursos covid-19 study group Department of Health Psychology and Center for Applied Psychology Universidad Miguel HernándezElche 03202AlicanteSpain Department of Basic and Clinical Psychology and Psychobiology Universitat Jaume ICastellóde la Plana 12071CastellónSpain

BACKGROUND There is mounting empirical evidence of the detrimental effects of the coronavirus disease 2019(covid-19)outbreak on mental *** research has underscored the effects of similar destabilizing situations such as war,natural disasters or other pandemics on acute stress levels which have been shown to exacerbate current and future psychopathological *** To explore the role of acute stress responses(intrusive,avoidance and hyperarousal)as mediators in the association between fear of covid-19 and emotional dysfunction-related problems:Depression,agoraphobia,panic,obsessivecompulsive,generalized anxiety,social anxiety and health anxiety *** A sample of 439 participants from a university community in Spain(age:mean±SD:36.64±13.37;73.1%females)completed several measures assessing their fear of covid-19,acute stress responses and emotional dysfunction syndromes through an online *** collection was carried out from the start of home confinement in Spain until May 4,2020,coinciding with initial de-escalation *** of the dataset included descriptive and frequency analyses,Mann-Whitney U Test of intergroup comparisons and path analysis for direct and indirect *** is an observational,descriptive-correlational and crosssectional *** The prevalence of clinical symptoms in our sample,reported since the beginning of the pandemic,reached 31.44%.The female group presented higher scores although the effect size was ***,the participants who exceeded the clinical cut-off points in emotional problems showed higher levels of fear of covid-19 and of cognitive,motor and psychophysiological responses of acute stress,unlike the group with normative *** addition,the results show significant mediated effects of hyperarousal stress among fear of covid-19 and emotional dysfunction ***,the clinical syndromes most related to the consequences of the pandemic(e.g.,social contact avoi

关键词： Fear of covid-19 Acute stress Emotional dysfunction Psychophysiological activation Mediated effects

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Report on Childhood Obesity in China (1) Body Mass Index Reference for Screening Overweight and Obesity in Chinese School-age Children

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Biomedical and Environmental Sciences 2005年第6期18卷 390-400页

作者： COOPERATIVE study ON CHILDHOOD OBESITY WORKING group ON OBESITY IN CHINA (WGOC) Institute of Child and Adolescent Health

Purpose To establish and propose a national body mass index （BMI） reference for screening overweight and obesity in Chinese school-age children and adolescents. Methods 2000 CNSSCH （Chinese National Survey on Students Constitution and Health） data, including 216 620 primary and secondary school students aged 7 to 18 years old, were used as a reference population. Compared with those of the NCHS intematioanl reference, three temporary sets of cut-off BMI were proposed by testing different combinations of P85, P90, and P95. When physiological and biochemical measures between and among “obesity” “overweight”, and “normal weight” groups were taken into consideration, set Ⅱ was selected to be the most appropriate one. The sex-age-specific curves were then plotted and smoothed by using B-spline method. Results Based on the samples from costal developed metropolis, the BMI curves successfully overcame the shortcomings of lower and level-off tendency of the Chinese total population. Temporary set H, composed by cut-offs of P85 for overweight and P95 for obesity, was finally selected by its sensitivity and peculiarity. BMI 24 and 28 were used as cut-offs for overweight and obesity for both males and females aged 18 years old. These cut-offs, consistent with Chinese Adult＇s Reference, was proposed as the Body mass index reference for screening overweight and obesity in Chinese school-age children and adolescents. Conehlsion The new reference clearly showed its superiorty in both prospectivity and actuality. The proposed reference minimized the gaps of the BMI curve between Chinese adolescents and the international reference. Most importantly was that it was consistent with the Eastern Asia ethnic characteristics of body fatness growth. It was therefore proposed by the Working group on Obesity in China （WGOC） to use it as an nationwide reference for screening overweight and obesity of school-age children and adolescents in China.

关键词： Body mass index, Chinese school-age children Overweight Reference

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Real-World Treatment Adherence to Smoking Cessation Medications and Association with Treatment Outcome—27 Centers,China,2017–2022

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China CDC weekly 2024年第22期6卷 522-529,I0001-I0003页

作者： Anqi Cheng Zhao Liu Xinmei Zhou Zheng Su Dan Xiao Chen Wang the China National Tobacco Cessation Cohort study(CNTCCS)study group Department of Tobacco Control and Prevention of Respiratory Disease Center of Respiratory MedicineChina-Japan Friendship Hospital/WHO Collaborating Center for Tobacco Cessation and Respiratory Diseases Prevention/National Center for Respiratory Medicine/National Clinical Research Center for Respiratory Diseases/Institute of Respiratory MedicineChinese Academy of Medical SciencesBeijingChina Department of Pulmonary and Critical Care Medicine Center of Respiratory MedicineChina-Japan Friendship Hospital/WHO Collaborating Center for Tobacco Cessation and Respiratory Diseases Prevention/China National Center for Respiratory Medicine/China National Clinical Research Center for Respiratory DiseasesBeijingChina Chinese Academy of Medical Sciences and Peking Union Medical College BeijingChina 不详

What is already known about this topic?Medication non-adherence significantly impedes smoking cessation *** effective smoking cessation medications are accessible in China,realworld adherence and its correlation with treatment outcomes remain largely *** is added by this report?From December 2017 to January 2022,1,120 participants were recruited from 27 centers in all seven geographical regions of *** revealed that only 38.2%of smokers adhered to the prescribed 12-week smoking cessation treatment and those with a higher education level were more likely to be *** addition,smokers with good adherence were more likely to successfully quit *** are the implications for public health practice?The data obtained could enhance our understanding of smoking cessation practices in *** adherence is a crucial strategy to enhance the effectiveness of smoking cessation treatments and management provided to smokers.

关键词： China smoke likely

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Gastroesophageal reflux disease management according to contemporary international guidelines:A translational study

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World Journal of Gastroenterology 2011年第9期17卷 1160-1166页

作者： Fabio Pace Gabriele Riegler Annalisa de Leone Patrizia Dominici Enzo Grossi the EMERGE study group Division of Gastroenterology Department of Clinical Sciences 'L. Sacco' UniversityHospital 74-20157 Milano Italy 'Magrassi-Lanzara' Department of Clinicaland Experimental Medicine 2nd University of Naples 80100Naples Italy Medical Department BraccoImaging SpA 24100 Milano Italy

AIM:To test the Genval recommendations and the usefulness of a short trial of proton pump inhibitor(PPI) in the initial management and maintenance treatment of gastroesophageal reflux disease(GERD)patients. METHODS:Five hundred and seventy seven patients with heartburn were *** completing a psychometric tool to assess quality of life(PGWBI)and a previously validated GERD symptom questionnaire (QUID),patients were grouped into those with esophagitis(EE,n=306)or without mucosal damage (NERD,n=271)according to endoscopy results. The study started with a 2-wk period of high dose omeprazole(omeprazole test);patients responding to this PPI test entered an acute phase(3 mo)of treatment with any PPI at the standard ***,those patients with a favorable response to the standard PPI dose were maintained on a half PPI dose for a further 3-mo period. RESULTS:The test was positive in 519(89.9%)patients,with a greater response in EE patients(96.4%) compared with NERD patients(82.6%)(P=0.011). Both the percentage of completely asymptomatic patients,at 3 and 6 mo,and the reduction in heartburn intensity were significantly higher in the EE compared with NERD patients(Pgroups when compared with the mean value in a reference Italian population. CONCLUSION:Our study confirms the validity of the Genval guidelines in the management of GERD patients. In addition,we observed that the overall response to PPI therapy is lower in NERD compared to EE patients.

关键词： Gastroesophageal reflux disease Proton pump inhibitors Nonerosive gastroesophageal reflux Questionnaire Quality of life

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A combined treatment for patients with dry eye and associated laryngopharyngeal reflux:a real-life approach

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International Journal of Ophthalmology(English edition) 2023年第10期16卷 1616-1622页

作者： Giorgio Ciprandi Stefano Bonini Irene Schiavetti Valerio Damiani study group on Dry-Eye Pragmatical Management Allergy Clinic Casa di Cura Villa MontallegroGenoa 16145Italy Ophthalmology Complex Operative Unit University Campus Bio-MedicoRome 00100Italy Health Science Department University of GenoaGenoa 16142Italy Medical Department DMGPomezia 00070Italy 不详

AIM:To evaluate the efficacy and tolerability of administering a combined therapy in patients with dry eye syndrome(DES)and associated laryngopharyngeal reflux(LPR).METHODS:The study was retrospective,open,observational,and conducted in a real-life *** had pathological symptom assessment in dry eye(SANDE)and reflux symptom index(RSI)at *** were re-assessed after 1mo and at the end of *** treatment consisted of a three-month course based on the combined therapy:Gastroftal eye drops,one drop three times a day,and Gastroftal tablets,two tablets after lunch and two tablets after *** break-up-time(TBUT)test,Schirmer test,RSI,and SANDE questionnaire were ***:The study included 253 *** mean age was 58±*** test score and Schirmer’s test significantly increased(both Pstudy shows that combined therapy using Gastroftal eye drops and tablets could represent a valuable option in managing patients with DES associated with LPR.

关键词： dry eye syndrome laryngopharyngeal reflux combined therapy hyaluronic acid alginate Camelia sinensis real-life

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Strategies to control myopia in children:a review of the findings from the Anyang Childhood Eye study

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Annals of Eye Science 2018年第1期3卷 219-225页

作者： Shi-Ming Li Ningli Wang the Anyang Childhood Eye study group Beijing Tongren Eye Center Beijing Tongren HospitalBeijing Ophthalmology&Visual Science Key LabBeijing Institute of OphthalmologyCapital Medical UniversityBeijing 100000China

Myopia in children remains a major public health problem worldwide,especially in some Asian countries such as China,Singapore and *** many interventions have been attempted,few has been proven to be effective in controlling onset and progression of myopia in *** factors,genetic susceptibility or ethnic differences can affect the efficacy of these ***,many questions remain unclear and even controversial for controlling *** has the biggest population with myopia,especially for children ***,it is of importance to present what achievements Chinese scientists have made in the field of myopia control in *** summarize the current findings on myopia control in children from the Anyang Childhood Eye study,including epidemiological data,clinical trials,systematic reviews and meta-analyses,and compare them with studies in other countries to find potential clues for controlling myopia in children.

关键词： Children myopia time outdoors near work Chinese eye exercises spectacles

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The Handan Offspring Myopia study

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Annals of Eye Science 2018年第1期3卷 341-344页

作者： Caixia Lin Ningli Wang Handan Offspring Myopia study group Beijing Tongren Eye Center Beijing Tongren HospitalBeijing Ophthalmology&Visual Science Key LabBeijing Institute of OphthalmologyCapital Medical UniversityBeijing 100730China

The Handan Offspring Myopia study(HOMS),whose participants came from 6 villages where all people aged≥30 years had taken part in the Handan Eye study(HES)in 2006-2007,was designed to obtain the familial associations of myopia between parents and their *** March 2010 to June 2010,of 1,238 eligible individuals,878 children(70.2%;52.6%male)from 541 families were *** mean age of the children was 10.5±2.5 *** the participants had a detailed eye examination and anthropometry *** examinations were performed using the same protocols and equipment in both HES and *** of the parents was obtained from the *** results of the research showed that the myopic shift from parents to children was estimated to be approximately 1 D at 18 years of *** near work and myopia,no association was found,except for the high near work subgroup with moderate outdoor activity *** a weak protective effect of outdoor activity on myopia in these rural children was *** the future,we plan to follow up these participants and investigate how the refraction of the children change,how myopia-genic activity changes and what effect does it have on *** information will be important for the design of strategies to prevent and reduce myopia.

关键词： Children epidemiology myopia offspring

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科技兴贸的内涵与关键技术研究报告

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财经研究 1994年第6期20卷 3-14页

作者： ( The study group)

科技兴贸的内涵与关键技术研究报告上海财经大学《科技兴贸与关键技术研究》课题组。．ＡＳｔｕｄｙｏｆＣｏｎｎｏｔａｔｉｏｎｉｎＤｅｖｅｌｏｐｉｎｇＣｏｍｍｅｒｃｅｂｙＳｃｉｅｎｃｅａｎｄＴｅｃｈｎｏｌｏｇｙ￥（ＴｈｅＳｔ... 详细信息

科技兴贸的内涵与关键技术研究报告上海财经大学《科技兴贸与关键技术研究》课题组。．ＡＳｔｕｄｙｏｆＣｏｎｎｏｔａｔｉｏｎｉｎＤｅｖｅｌｏｐｉｎｇＣｏｍｍｅｒｃｅｂｙＳｃｉｅｎｃｅａｎｄＴｅｃｈｎｏｌｏｇｙ￥（ＴｈｅＳｔｕｄｙＧｒｏｕｐ）Ｉｎｔｈｅｓｙｓ...

关键词：科技兴贸第三产业技术进步上海

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Ocular Trauma in a Rural Population of North China:The Handan Eye study

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Biomedical and Environmental Sciences 2015年第7期28卷 495-501页

作者： ZHOU Jun WANG Feng Hua LU Hai LIANG Yuan Bo WANG Ning Li the Handan Eye study group Beijing Tongren Eye Center Capital Medical University Handan Eye Hospital School of Optometry and Ophthalmology Eye Hospital Wenzhou Medical University

Objective To determine the prevalence of ocular trauma and the proportion of blindness and visua impairment due to trauma in a rural population in northern China. Methods The Handan Eye study is a population-based cross-sectional study that surveyed 6830 Chinese people aged 30＋ years from 13 randomly selected villages in Yongnian County, city of Handan, Hebei Province, in July, 2006. All participants underwent a standardized interview and extensive examinations. A structured questionnaire was used to collect information on ocular trauma. Results Of the 5837 participants who filled out the questionnaire, 124 subjects [2.1%; 95% confidence interval （CI）, 1.8%-2.5%] reported a history of ocular trauma in either eye, including 19 （0.3%） persons reporting trauma in both eyes. Men were more likely to have an eye injury than women [odds ratio （OR）, 3.3; 2.2-4.9]. In multiple logistic regression models, ocular trauma was significantly more frequent among normotensive participants when compared with hypertensive participants （hypertensive vs. normotensive＂ OR, 0.6; 0.4-0.9） and among participants who had a history of falls （OR, 2.4; 1.2-4.8）. The proportion of unilateral visual impairment and unilateral blindness due to trauma were 10.5% （13 subjects） and 21.0% （26 subjects）, respectively. Conclusion Our study reports the prevalence of severe ocular trauma among adults in rural China, revealing a high proportion of blindness and visual impairment due to trauma. These findings suggest the need for educational strategies to increase eye health awareness in this rural population with focus on providing at least appropriate first aid care to reduce blindness due to trauma.

关键词： Ocular trauma Population-based survey Prevalence Risk factor Handan Eye study

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covid-19-induced transaminitis and hyperbilirubinemia:Presentation and outcomes

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World Journal of Gastroenterology 2023年第7期29卷 1123-1130页

作者： Zeinab Nabil Ahmed Said Safinaz Adel El Habashy Samy Zaky ESCMID study group for Viral Hepatitis Department of Medical Microbiology and Immunology Faculty of Medicine(For Girls)Al-Azhar UniversityCairo 11754Nasr CityEgypt Department of Pediatrics Ain Shams UniversityCairo 11391AbbaseiaEgypt Department of Hepato-gastroenterology and Infectious Diseases Faculty of Medicine(For Girls)Al-Azhar UniversityCairo 11754Egypt 不详

The risk of liver injury in patients with coronavirus disease 2019(covid-19)infection is quite ***,liver function test abnormalities are still detected in covid-19 patients despite the development of antivirals and the availability of several types of *** editorial describes liver involvement during covid-19 infection in patients with or without preexisting liver injury,such as chronic liver disease,to elucidate covid-19-induced liver function abnormalities and their severity,pathophysiology,clinical manifestations,and clinical and laboratory *** also discuss the effect of vaccination against covid-19 to better understand host factors,such as age,gender,and race,on the incidence and severity of liver dysfunction at initial presentation and during the ***,we summarize the results of relevant meta-analyses published to date and highlight the importance of adequate liver function monitoring in the current climate of the overwhelming covid-19 pandemic.

关键词： covid-19 SARS-CoV-2 Liver injury Transaminases Hyperbilirubinemia Pathophysiology

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