检索结果-南通市图书馆

Optoelectronics Letters 2018年第6期14卷 465-469页

作者： priyamvada v c AJINA c RADHAKRISHNAN P International School of Photonics Cochin University of Science and Technology

The sensitivity of the plasmonic sensor surfaces can be enhanced significantly if the sensor region is bent to U shape. Here, an experimental verification is done to evaluate the performance variations of the U-bent plasmonic silver coated sensor surfaces with different coating orientations inside the vacuum coating chamber. The performances of uncoated, partially coated as well as fully coated optical fiber U-bent surfaces are analyzed. The results show that the coating configuration of the U-bent surfaces can affect the sensing property. A fully silver coated sensor region outperforms the other two types of sensor surfaces with better sensing capability.

关键词： coating configuration dependency fiber optic silver coated U-bent plasmonic sensor surfaces

Photoluminescence upgradation of La_(2)MgTiO_(6):2%Dy^(3+) perovskite with monovalent(Li^(+)),divalent(Ba^(2+),Sr^(2+)) and trivalent(Bi^(3+),Sm^(3+))cation sensitization

在线全文

学校读者我要写书评

暂无评论

Journal of Rare Earths 2025年第1期43卷 47-56,I0002页

作者： v.P.veena K.Arun c.K.Shilpa S.v.Jasira K.M.Nissamudeen School of Pure and Applied Physics Kannur UniversityPayyanur CampusEdatKannurKrala67 India Department of Nanoscience and Nanotechnology Kannur UniversityPayyanur CampusEdatkannurKerala670327India

Nano phosphors of 2%Dy^(3+)(wt%)doped La_(2)MgTiO_(6) and monovalent/divalent/trivalent co-doped La_(1.98)Dy_(0.02)MgTiO_(6):x%A^(y+)(A^(y+):Li+,Ba^(2+),Sr^(2+),Bi^(3+),and Sm^(3+);0≤x≤2 wt%)were synthesized by combustion *** the XRD data,it is deduced that an increase in the valency of co-dopant increases the crystallinity of the double perovskite orthorhombic nanocrystal *** an increase in co-dopant size,an elevation in optical bandgap is visible with the highest bandgap of 3.835 ev for Bi^(3+).The photo-absorption is monotonically broadened for Sr^(2+),Sm^(3+),and Li+around 200-450 ***351 nm,Dy^(3+)triggered lattice shows major characteristic emission peaks at 480 nm(^(4)F_(9/2)→^(6)H_(15/2)),574 nm(^(4)F_(9/2)→^(6)H_(13/2)),and 670 nm(^(4)F_(9/2)→^(6)H_(11/2)).leading to near white light emission with cIE coordinates(0.341,0.376).Upon co-doping,the PL intensity is significantly increased with maximum emission for trivalent Sm^(3+),followed by divalent Sr^(2+)and monovalent Li+*** increasing excitation wavelength,Sr^(2+)shows a dominated output and it is found that divalent Sr^(2+)is a potential codopant that could enhance luminescence intensity up to 6 times with a Sr^(2+)→Dy^(3+)energy transfer efficiency of 86%.It is specified that the cIE coordinates of Li+co-doped samples show ideal white emission with color coordinates(0.333,0.336).The concluding outcomes signify the noblest rare earth Sm^(3+)co-doping and thus Sm^(3+)→Dy^(3+)energy transfer mechanism is discussed in detail.

关键词： Photoluminescence Perovskite WLED co-doping Rareearths

MicroRNAs as potential diagnostic biomarkers for bipolar disorder

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第6期20卷 1681-1695页

作者： Bridget Martinez Philip v.Peplow Department of Pharmacology University of Nevada-RenoRenoNVUSA Department of Medicine University of Nevada-RenoRenoNVUSA Department of Anatomy University of OtagoDunedinNew Zealand

Abnormal expression of microRNAs is connected to brain development and disease and could provide novel biomarkers for the diagnosis and prognosis of bipolar disorder. We performed a PubMed search for microRNA biomarkers in bipolar disorder and found 18 original research articles on studies performed with human patients and published from January 2011 to June 2023. These studies included microRNA profiling in bloodand brain-based materials. From the studies that had validated the preliminary findings,potential candidate biomarkers for bipolar disorder in adults could be miR-140-3p,-30d-5p,-330-5p,-378a-5p,-21-3p,-330-3p,-345-5p in whole blood, miR-19b-3p,-1180-3p,-125a-5p, let-7e-5p in blood plasma, and miR-7-5p,-23b-5p,-142-3p,-221-5p,-370-3p in the blood serum. Two of the studies had investigated the changes in microRNA expression of patients with bipolar disorder receiving treatment. One showed a significant increase in plasma miR-134 compared to baseline after 4 weeks of treatment which included typical antipsychotics, atypical antipsychotics, and benzodiazepines. The other study had assessed the effects of prescribed medications which included neurotransmitter receptorsite binders(drug class B) and sedatives, hypnotics, anticonvulsants, and analgesics(drug class c) on microRNA results. The combined effects of the two drug classes increased the significance of the results for miR-219 and-29c with miR-30e-3p and-526b* acquiring significance. MicroRNAs were tested to see if they could serve as biomarkers of bipolar disorder at different clinical states of mania, depression, and euthymia. One study showed that upregulation in whole blood of miR-9-5p,-29a-3p,-106a-5p,-106b-5p,-107,-125a-3p,-125b-5p and of miR-107,-125a-3p occurred in manic and euthymic patients compared to controls, respectively, and that upregulation of miR-106a-5p,-107 was found for manic compared to euthymic patients. In two other studies using blood plasma,downregulation of miR-134 was observed i

关键词： biomarker bipolar disorder blood leukocytes blood plasma blood plasma extracellular vesicles/exosomes blood serum brain tissue brain tissue extracellular vesicles/exosomes lymphoblastoid cell lines microRNA neural progenitor cells whole blood

MicroRNAs as potential biomarkers for diagnosis of post-traumatic stress disorder

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第7期20卷 1957-1970页

Post-traumatic stress disorder is a mental disorder caused by exposure to severe traumatic life ***,there are no validated biomarkers or laboratory tests that can distinguish between trauma survivors with and without post-traumatic stress *** addition,the heterogeneity of clinical presentations of post-traumatic stress disorder and the overlap of symptoms with other conditions can lead to misdiagnosis and inappropriate *** suggests that this condition is a multisystem disorder that affects many biological systems,raising the possibility that peripheral markers of disease may be used to diagnose post-traumatic stress *** performed a PubMed search for microRNAs(miRNAs)in post-traumatic stress disorder(PTSD)that could serve as diagnostic biomarkers and found 18 original research articles on studies performed with human patients and published January 2012 to December *** included four studies with whole blood,seven with peripheral blood mononuclear cells,four with plasma extracellular vesicles/exosomes,and one with serum *** of these studies had also used whole *** studies were excluded as they did not involve microRNA *** of the studies had collected samples from adult male veterans who had returned from deployment and been exposed to combat,and only two were from recently traumatized adult *** measuring miRNA expression levels,many of the studies had used microarray miRNA analysis,miRNA Seq analysis,or NanoString *** six studies had used real time polymerase chain reaction assay to determine/validate miRNA expression in PTSD subjects compared to *** miRNAs that were found/validated in these studies may be considered as potential candidate biomarkers for PTSD and include miR-3130-5p in whole blood;miR-193a-5p,-7113-5p,-125a,-181c,and-671-5p in peripheral blood mononuclear cells;miR-10b-5p,-203a-3p,-4488,-502-3p,-874-3p,-5100,and-7641 in plasma extracellular vesicles/

关键词： biomarker diagnosis microRNA peripheral blood mononuclear cells plasma extracellular vesicles/exosomes post-traumatic stress disorder serum exosomes whole blood whole plasma

controversies in fecal incontinence

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2025年第3期31卷 113-119页

作者： Andreia Albuquerque Satish S c Rao School of Medicine and Biomedical Sciences Fernando Pessoa UniversityGondomar 4420-096PortoPortugal Precancerous Lesions and Early cancer Management Research Group RISE@cI-IPO(Health Research Network) Portuguese Oncology Institute of PortoPorto 4200-072Portugal Division of Gastroenterology and Hepatology Department of Internal MedicineAugusta UniversityAugustaGA 30912United States

Fecal incontinence is a common condition that can significantly impact patients’quality of *** anal sphincter injury and anorectal surgeries are common *** ultrasound and anorectal manometry are important diagnostic tools for evaluating *** are various treatment options,including diet,lifestyle modifications,drugs,biofeedback therapy,tibial and sacral nerve neuromodulation therapy,and *** this editorial,we will discuss current controversies and novel approaches to fecal *** for asymptomatic anal sphincter defects after obstetric anal sphincter injury and in patients with inflammatory bowel disease is not generally recommended,but may be helpful in selected *** Garg incontinence score is a new score that includes the assessment of solid,liquid,flatus,mucous,stress and urge fecal *** tests such as translumbosacral anorectal magnetic stimulation and novel therapies such as translumbosacral neuromodulation therapy are promising diagnostic and treatment options,for both fecal incontinence and *** biofeedback therapy can overcome some limitations of the office-based *** muscle-derived cell implantation of the external anal sphincter has been further studied as a possible treatment *** neuromodulation may be useful in scleroderma,congenital fecal incontinence and inflammatory bowel disease but merits further study.

关键词： Fecal incontinence Endoanal ultrasound Anal sphincter defects Biofeedback Neuropathy Sacral neuromodulation

A comprehensive investigation on nonlinear vibration and bending characteristics of bio-inspired helicoidal laminated composite structures

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 81-100页

作者： S.SAURABH R.KIRAN D.SINGH R.vAISH v.S.cHAUHAN School of Mechanical and Materials Engineering Indian Institute of Technology Mandi

Bio-inspired helicoidal composite laminates, inspired by the intricate helical structures found in nature, present a promising frontier for enhancing the mechanical properties of structural designs. Hence, this study provides a comprehensive investigation into the nonlinear free vibration and nonlinear bending behavior of bio-inspired composite plates. The inverse hyperbolic shear deformation theory(IHSDT) of plates is employed to characterize the displacement field, with the incorporation of Green-Lagrange nonlinearity. The problem is modeled using the c0finite element method(FEM), and an in-house code is developed in the MATLAB environment to solve it numerically. various helicoidal layup configurations including helicoidal recursive(HR), helicoidal exponential(HE), helicoidal semi-circular(HS), linear helicoidal(LH), and Fibonacci helicoidal(FH)with different layup sequences and quasi-isotropic configurations are studied. The model is validated, and parametric studies are conducted. These studies investigate the effects of layup configurations, side-to-thickness ratio, modulus ratios, boundary conditions, and loading conditions at different load amplitudes on the nonlinear vibration and nonlinear bending behaviors of bio-inspired composite plates. The results show that the laminate sequence exerts a substantial impact on both nonlinear natural frequencies and nonlinear bending behaviors. Moreover, this influence varies across different side-to-thickness ratios and boundary conditions of the bio-inspired composite plate.

关键词： bio-inspired composite plate finite element method (FEM) Green-Lagrange helicoidal inverse hyperbolic shear deformation theory (IHSDT) nonlinear O322

Modeling net-charge fluctuations in heavy-ion collisions at the LHc

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

chinese Physics c 2025年第1期49卷 281-289页

作者： G.O.Ambaryan A.S.chernyshov G.Kh.Eyyubova v.L.Korotkikh I.P.Lokhtin S.v.Petrushanko A.M.Snigirev E.E.Zabrodin Physics Department Lomonosov Moscow State UniversityRU-119991 MoscowRussia Skobeltsyn Institute of Nuclear Physics Lomonosov Moscow State UniversityRU-119991 MoscowRussia Bogoliubov Laboratory of Theoretical Physics Joint Institute for Nuclear ResearchRU-141980 DubnaRussia Department of Physics University of OsloN-0316 OsloNorway

Analysis of Pb+Pb data for net-charge fluctuations at LHc energies using the HYDJET++model is *** strongly intensive quantities D and Σ were used to remove the effects related to system volume *** employed two versions of HYDJET++for the *** first one is the standard or default version,whereas the second one is a modification that takes into account explicit event-by-event conservation of the electric net-charge of produced *** inclusion of the canonical net-charge conservation in the model allows for better description of the experimental data obtained by the ALIcE and cMS collaborations.A comparison with calculations from other models is also presented.

关键词： relativistic heavy-ion collisions net-charge fluctuations strongly intensive variables canonical charge conservation

Human health risks associated to trace elements and metals in commercial fish from the Brazilian Amazon

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2025年第2期148卷 230-242页

作者： Andrea v.Waichman Gabriel Silva de Souza Nunes Rhaul de Oliveira Isabel López-Heras Andreu Rico Federal University of the Amazon Institute of Biological SciencesAv.Rodrigo Ramos 3000Manaus 69077-000Brazil Federal University of Pernambuco Department of ZoologyAv.Prof Moraes Rego 1235Cidade UniversitáriaRecife 50670-901Brazil University of campinas School of TechnologyRua Paschoal Marmo 1888-Jd.Nova ItáliaLimeira 13484-332Brazil IMDEA Water Institute Science and Technology Campus of the University of AlcaláAv.Punto Com 2Alcaláde Henares 28805MadridSpain cavanilles Institute of Biodiversity and Evolutionary Biology University of Valenciac/Catedrático JoséBeltrán 246980PaternaValenciaSpain

Fish constitutes the main protein source for the Amazonian ***,the impact of different anthropogenic activities on trace element and metal accumulation in fish and their risks for human health at a regional scale remain largely *** we assessed exposure levels of 10 trace elements andmetals(cr,Mn,Fe,Ni,cu,Zn,As,cd,Pb,and Hg)in 56 samples belonging to 11 different species of fish from the Brazilian *** studied the relationship between exposure levels,fish origin,and fish feeding habits,and assessed toxicological and carcinogenic risks for the Amazonian *** significant correlation was found between sampling site and exposure levels to the studied elements,but a significant difference was found between the accumulation of some metals and the position of the fish species in the food *** concentrations of cr and Hg in fish flesh were found to exceed the Brazilian limits for human *** study shows that current fish consumption patterns can lead to estimated daily intakes of Hg,As and cr that exceed the oral reference dose,thus posing a toxicological ***,carcinogenic risks may be expected due to the continued exposure to cr and *** results of this study show that the consumption of wild caught fish in the Amazon region should be ***,continued monitoring of trace element and metal contamination in fish and on the health of the Amazonian population is recommended,particularly for riverine and indigenous communities.

关键词： Metals Deforestation Mining Freshwater ecosystems carcinogenic risks Amazon

A simple method for automatic recreation of railway horizontal alignments

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Railway Engineering Science 2025年第1期33卷 62-78页

作者： Alberte castro Gerardo casal Duarte Santamarina Miguel E.vázquez‑Méndez Transportation and Infrastructure Engineering Universidade de Santiago de CompostelaEPSERúa Benigno Ledo27002 LugoSpain Department of Applied Mathematics Universidade de Santiago de CompostelaEPSERúa Benigno Ledo27002 LugoSpain cITMAga Rúa de Constantino Candeira15782 Santiago de CompostelaSpain

This paper deals with the problem of recreating horizontal alignments of existing railway *** main objective is to propose a simple method for automatically obtaining optimized recreated alignments located as close as possible to an existing *** on a previously defined geometric model,two different constrained optimization problems are *** first problem uses only the information provided by a set of points representing the track centerline while the second one also considers additional data about the existing *** proposed methodology consists of a two-stage process in which both problems are solved consecutively using numerical *** main results obtained applying this methodology are presented to show its performance and to prove its practical usefulness:an academic example used to compare with other methods,and a case study of a railway section located in Parga(Spain)in which the geometry of its horizontal alignment is successfully recovered.

关键词： Railway horizontal alignment Geometrical model constrained optimization problem Numerical resolution

Links of Terrestrial Environment with Solar Activity and Solar and Planetary Orbital Motion

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Atmospheric and climate Sciences 2025年第1期15卷 72-105页

作者： valentina v. Zharkova Irina vasilieva Department of MPEE Faculty of Engineering and Environment University of Northumbria Newcastle upon Tyne UK ZvS Research Enterprise Ltd. London UK Department of Solar Physics Main Astronomical Observatory Kyiv Ukraine

In this paper we emphasize statistical links between solar activity and orbital motion with various terrestrial phenomena: terrestrial temperature, sea levels, ice areas, frequencies of volcanic eruptions, and Oceanic Nino Index (ONI). Solar activity links. The solar activity indices are expressed through the averaged sunspot numbers SSN and the summary curve of eigen vectors of the solar background magnetic field (SBMF). The terrestrial temperature (GLB dataset), global sea level, and volcanic eruption frequencies are shown from the wavelet analysis to have a clear link to the SBMF index, which has the same significant period of 21.4 years. The ice and snow areas in the Northern hemisphere are found to vary with a period of 10.7 years equal to the usual sunspot activity cycle while in the Southern hemispheres, no links to solar activity are detected. Solar orbital motion links. The variations of total solar irradiance (TSI) measured from the abundance of 14c isotope during the Holocene are shown to have a similar period of 2200-2300 years (Hallstatt’s cycle) as the solar inertial motion (SIM) induced by the gravitation of large planets, In the current millennium the amount of TSI deposited on Earth in the March-September to Northern hemisphere is ≈1.2% higher than in the September to March in the Southern hemisphere. The wavelet analysis of ONI revealed the two significant periods of 4.5 and 12 years. The first one is shown to have a link to the lunar perigee period variations while the second period is linked to the Jupiter period of revolution about the Sun whose gravitation seems to trigger terrestrial tectonic processes leading to volcanic eruptions. The ONI variation is noticeably linked to the occurrence of underwater volcanic eruptions (correlation of 25%), which, in turn, are linked to the tidal forces of Jupiter, the Moon and the Sun in its inertial motion. Joint effects of the solar activity and the solar and planetary orbital motion are likely to govern

关键词： Terrestrial Temperature Terrestrial Sea Level Terrestrial Ice Areas El Nino Southern Oscillation volcanic Eruptions Underwater volcanic Eruptions Solar Magnetic Field Solar Activity Solar Inertial Motion correlation Jupiter Revolution Period Lunar Perigee Period