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Bofedal response to climate variability, local management, and water extraction: A case study of Chucuyo, Northern Chile

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Journal of Mountain Science 2022年第1期19卷 241-252页

作者： URIBE-ÁLVAREZ Monserrat C prieto manuel MESEGUER-RUIZ Oliver Departamento de Ciencias Históricas y Geográficas Universidad de TarapacáArica 1010069Chile Departamento de Ciencias Históricas y Geográficas Universidad de TarapacáIquique 1101783Chile

Andean high-altitude wetlands are important ecosystems that serve a range of socialecological functions. In the Andes, bofedales, a specific type of peat-producing wetland, are essential for the sustainability of mountain ecosystems and indigenous pastoralist communities. The Chucuyo bofedal in northern Chile is affected by climatic variability and water extraction for agricultural uses via the Lauca canal. Herders in the local community also actively manage this wetland according to their traditional ecological knowledge to ensure permanent fodder for their animals. In this article, we analyze the annual behavior of the Chucuyo bofedal after the wet season. Based on precipitation data, extracted water flows, vegetation vigor from satellite images, and an ethnographic approach, we determined that the bofedal’s productivity was negatively correlated with the amount of precipitation and positively correlated with the surface area of the wetland. However, water extraction via the Lauca channel had no significant relationship with either surface area or vegetation vigor. We identify community practices and traditional ecological knowledge as key elements in the maintenance of these ecosystems. This situation is critical in the context of an aging population and the current pattern of migration out of the region to urban areas. The results provide substantial empirical evidence for future decision-making regarding the conservation of these ecosystems.

关键词： Atacama Bofedales Indigenous people Lauca canal Normalized Difference Vegetation Index

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Determining the need for a thoracoscopic approach to treat a giant hiatal hernia when abdominal access is poor

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World Journal of Gastrointestinal Surgery 2023年第12期15卷 2739-2746页

作者： Francisco Javier Pérez Lara Rogelio Zubizarreta Jimenez Tatiana prieto-Puga Arjona Pilar Gutierrez Delgado Juan manuel Hernández Carmona Jose manuel Hernández Gonzalez Maria Pitarch Martinez Department of Surgery Hopital de AntequeraAntequera 29200Spain DOXA MicrofluidicsRincon de la Victoria 29730Spain Department of Surgery HRU Carlos HayaUnidad Cirugia Hepatobiliopancreat&TrasplantesMalaga 29200Spain

BACKGROUND Giant hernias present a significant challenge for digestive surgeons.The approach taken(laparoscopic vs thoracoscopic)depends largely on the preferences and skills of each surgeon,although in most cases today the laparoscopic approach is preferred.AIM To determine whether patients presenting inadequate laparoscopic access to the intrathoracic hernial sac obtain poorer postoperative results than those with no such problem,in order to assess the need for a thoracoscopic approach.METHODS For the retrospective series of patients treated in our hospital for hiatal hernia(n=112),we calculated the laparoscopic field of view and the working area accessible to surgical instruments,by means of preoperative imaging tests,to assess the likely outcome for cases inaccessible to laparoscopy.RESULTS Patients with giant hiatal hernias for whom a preoperative calculation suggested that the laparoscopic route would not access all areas of the intrathoracic sac presented higher rates of perioperative complications and recurrence during follow-up than those for whom laparoscopy was unimpeded.The difference was statistically significant.Moreover,the insertion of mesh did not improve results for the non-accessible group.CONCLUSION For patients with giant hiatal hernias,it is essential to conduct a preoperative evaluation of the angle of vision and the working area for surgery.When parts of the intrathoracic sac are inaccessible laparoscopically,the thoracoscopic approach should be considered.

关键词： Hiatal hernia Abdominal surgery Laparoscopy Thoracoscopy surgery

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Therapeutic potential of lysosomal cathepsins for neurodegenerative diseases

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中国神经再生研究：英文版 2023年第8期18卷 1713-1714页

作者： Susy prieto Huarcaya Friederike Zunke Department of Molecular Neurology University Hospital ErlangenFriedrich-Alexander-Universität Erlangen-NürnbergErlangenGermany

Lysosomes are ubiquitous and dynamic organelles with a central role in degradation and recycling of damaged cell components and misfolded proteins,otherwise known as autophagy.Autophagy plays a fundamental role in the process of correcting cell homeostasis and cellular survival.Unsurprisingly,this process is essential in the central nervous system,as neurons are not able to easily eliminate altered proteins given their post-mitotic state.

关键词： homeostasis diseases otherwise

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Combination of Interleaved Single-input Multiple-output DC-DC Converters

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CSEE Journal of Power and Energy Systems 2022年第1期8卷 132-142页

作者： Eladio Dur´an Aranda Salvador P´erez Litr´an Mar´ıa Bella Ferrera prieto Electronic Engineering Computer Systems and Automation DepartmentUniversity of HuelvaHuelvaSpain Electrical and Thermal Engineering Design and Projects DepartmentUniversity of HuelvaHuelvaSpain

This paper analyses,simulates and verifies an experimental prototype of a four-phase interleaved DC-DC converter.It is based on a SEPIC-Cuk combination.The developed prototype has been used in single-input multiple-output(SIMO)applications.This combined converter allows obtaining dual output voltages of the same value,from a single input DC voltage and with only a power switch.Multiphase interleaved DC-DC converters achieve a better dynamic response and low ripple,maintaining their efficiency.Each converter is connected in parallel,thereby managing their losses by distributing them between more components,which facilitates the thermal management of the multiphase converter and allows handling high power values in small sizes with respect to solutions for a single phase.Two control strategies were applied:synchronous operation mode(SOM)and interleaved operation mode(IOM).The simulation results allow the comparison of both operational modes,verifying that the IOM presents advantages with respect to the ripple at the input and output currents.The experimental prototype was designed for a distributed power architecture and bipolar DC microgrid(MG).

关键词： Bipolar DC DC-DC converter interleaved

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Evaluation of remote radiologist-interpreted point-of-care ultrasound for suspected dengue patients in a primary health care facility in Colombia

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Infectious Diseases of Poverty 2023年第5期12卷 45-57页

作者： Lyda Osorio Iñigo prieto Daniela Zuluaga Deliana Ropero Neelesh Dewan Jonathan D.Kirsch Epidemiology and Population Health Research Group(GESP) School of Public HealthUniversidad del ValleCaliColombia Department of Radiology School of MedicineUniversidad del ValleCaliColombia Division of General Internal Medicine Department of Internal MedicineUniversity of Minnesota Medical SchoolMinneapolisMN 55455USA Department of Internal Medicine University of Miami Miller School of MedicineMiamiFLUSA

Background Early identification of plasma leakage may guide treatment decisions in dengue patients.This study evaluated the value of point-of-care ultrasound(POCUS)to detect plasma leakage and predict hospitalization or referral to a higher level of care in suspected dengue patients under routine conditions at a primary care facility in Colombia.Methods We conducted a cohort study between April 2019 and March 2020 in a primary care hospital in Cali,Colombia.We prospectively included and followed 178 patients who were at least 2 years old with fever of less than 10 days and clinician-suspected dengue.A trained general practitioner performed a standardized POCUS protocol.Images were quality-rated and overread by an expert radiologist,and her results and those of the general practitioner were compared using the Kappa index.Logistic regression was used to identify factors associated with plasma leakage at enrollment and explore its prognostic value regarding hospital admission or referral to a higher level of care.Results Half(49.6%)POCUS images were of suitable quality to be interpreted.The proportion of plasma leakage reported by the radiologist was 85.1%(95%CI:78.6-90.2%)and 47.2%by the study physician(Kappa=0.25,95%CI:0.15-0.35).The most frequent ultrasound findings were ascites(hepatorenal 87.2%,splenorenal 64%,or pelvic 21.8%)and gallbladder wall thickening(10.5%).Plasma leakage was higher in subjects with thrombocytopenia(aOR=4,95%CI:1.3-12.1)and lower in patients 30-59 years old(aOR=0.1,95%CI:0.0-0.4)than in those 18 years old or younger.POCUS evidence of plasma leakage(aOR=8.2,95%CI:2.2-29.9),thrombocytopenia(aOR=6.3,95%CI:2.4-16.0)and pulse pressure(aOR=1.1,95%CI:1.07-1.2)were associated with hospital admission or referral to a higher level of care.Conclusions Ultrasound is useful to detect plasma leakage in primary care and,challenges remain to guarantee high-quality images and diagnostic accuracy,for which a standardized dengue POCUS protocol and training program is needed.

关键词： Dengue Ultrasound Plasma leakage Primary care Colombia

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A computer vision system for early detection of anthracnose in sugar mango(Mangifera indica)based on UV-A illumination

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Information Processing in Agriculture 2023年第2期10卷 204-215页

作者： Leonardo Ramırez Alberto Carlos Eduardo Cabrera Ardila Flavio Augusto prieto Ortiz Facultad de Ingenierı´a Universidad Nacional de ColombiaBogota´D.C.111321Colombia

The present work describes the development of a computer vision system for the early detection of anthracnose in sugar mango based on Ultraviolet A illumination(UV-A).Anthracnose,a disease caused by the fungus Colletotrichum sp,is commonly found in the fruit of sugar mango(Mangifera indica).It manifests as surface defects including black spots and is responsible for reducing the quality of the fruit.Consequently,it decreases its commercial value.In more detail,this study poses a system that begins with image acquisition under white and ultraviolet illumination.Furthermore,it proposes to analyze the Red,Green and Blue color information(R,G,B)of the pixels under two types of illumination,using four different methods:RGB-threshold,RGB-Linear Discriminant Analysis(RGBLDA),UV-LDA,and UV-threshold.This analysis produces an early semantic segmentation of healthy and diseased areas of the mango image.The results showed that the combination of the linear discriminant analysis(LDA)and UV-A light(called UV-LDA method)in sugar mango images allows early detection of anthracnose.Particularly,this method achieves the identification of the disease one day earlier than by an expert with respect to the scale of anthracnose severity implemented in this work.

关键词： Sugar mango Anthracnose LDA UV-A light Grading Image processing

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A Passive Repression Mechanism that Hinders Synergic Transcriptional Activation by Heat Shock Factors Involved in Sunflower Seed Longevity

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Molecular Plant 2014年第1期7卷 256-259页

作者： Javier Tejedor-Cano Rail Carranco Jose-Maria Personat Pilar prieto-Dapena Concepcion Almoguera Jose manuel Espinosa Juan Jordano Departamento de Biotecnologia Vegetal tnstituto de Recursos Naturalesy Agrobiologia de Sevilla Consejo Superior de Investigaciones Cientificas (CSiC) Seville Spain

Different genetic programs that are active during late stages of zygotic embryogenesis are involved in seed phenotypes as longevity, basal thermotolerance, and desiccation tolerance. In sunflower, Heat Shock Factor A9 （HaHSFA9） controls one of such programs： the HaHSFA9 program. Overexpression of HaHSFA9 in seeds of transgenic tobacco showed the involvement of this transcription factor in basal thermotolerance and longevity;

关键词： PROTEINS AUX/IAA DOMAIN

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Philippine retinoblastoma initiative multi-eye center study 2010-2020

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International Journal of Ophthalmology(English edition) 2024年第1期17卷 144-156页

作者： Roland Joseph D.Tan Gary John V.Mercado Patricia E.Cabrera Paulita Pamela P.Astudillo Rolando Enrique D.Domingo Josept Mari S.Poblete Charmaine Grace M.Cabebe Adriel Vincent R.Te Melissa Anne S.Gonzales Jocelyn G.Sy Beltran Alexis A.Aclan Jayson T.So Fatima G.Regala Kimberley Amanda K.Comia Josemaria M.Castro Mara Augustine S.Galang Aldous Dominic C.Cabanlas Benedicto Juan E.Aguilar Gabrielle S.Evangelista Jo Michael Maniwan Andrei P.Martin Calvin Y.Martinez John Alfred H.Lim Rena Ivy Bascuna Rachel M.Ng Kevin B.Agsaoay Kris Zanna A.Acluba-Arao Ellaine Rose V.Apostol Beatriz M.prieto Department of Ophthalmology and Visual Sciences Philippine General HospitalManila 1000Philippines Department of Ophthalmology Baguio General Hospital and Medical CenterBaguio City 2600Philippines Department of Ophthalmology Manila Doctors HospitalManila 1000Philippines Department of Ophthalmology Rizal Medical CenterPasig City 1600Philippines Department of Ophthalmology Jose B.Lingad Memorial Regional HospitalPampanga 2000Philippines Department of Ophthalmology Southern Philippines Medical CenterDavao City 8000Philippines Department of Ophthalmology East Avenue Medical CenterQuezon City 1100Philippines Department of Ophthalmology Northern Mindanao Medical CenterCagayan de Oro City 9000Philippines Department of Ophthalmology Cebu Velez General HospitalCebu City 6000Philippines Legazpi Eye Center Legazpi City 4500Philippines Department of Ophthalmology Cagayan Valley Medical CenterTuguegarao City 3500Philippines

AIM:To provide a comprehensive and more representative national data on the disease,especially on treatment options and outcomes,and to determine access of retinoblastoma patients from Luzon,Visayas and Mindanao to eye care,and determine if access is associated with delay in consultation,staging and outcomes.METHODS:Cohort study of retinoblastoma patients seen in eleven institutions located in the three major areas of the Philippines namely Luzon,Vizayas and Mindanao from 2010-2020.RESULTS:Totally 636 patients,involving 821 eyes,were included.Majority(57%)were from Luzon and were seen in institutions in Luzon(72%).Annually,58±10 new cases were seen with 71%having unilateral disease.Median delay of consultation remained long at 9(3,17)mo,longest in patients with unilateral disease(P<0.02)and those from the Visayas(P<0.003).Based on the International Retinoblastoma Staging System,only 35%of patients had Stage 1 while 47%already had extraocular disease.Enucleation was the most common treatment received by 484 patients while intravenous chemotherapy was received by 469.There were 250(39%)patients alive,195(31%)dead,85(13%)abandoned,17(3%)refused and 89(14%)with no data.CONCLUSION:This study presents the largest cohort of retinoblastoma patients in the Philippines in terms of patients’and participating institutions’number and geographical location and type of institution(private and public).It also presents more comprehensive data on the treatments used and outcomes(survival,globe salvage,and vision retention rates).Delay in consultation was still long among patients leading to advanced disease stage and lower survival rate.Despite increasing capacity to diagnose and manage retinoblastoma in the country,the delay of consultation remains long primarily due to accessibility issues to eye care institutions especially in the Visayas and financial concerns.The delay was still significant that overall survival rate remain low.

关键词： retinoblastoma Philippines clinical profile

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Laser Wavelength Estimation Method Based on a High-Birefringence Fiber Loop Mirror

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Photonic Sensors 2019年第1期9卷 89-96页

作者： Ricardo I.ALVAREZ-TAMAYO Patricia prieto-CORTES manuel DURAN-SANCHEZ Baldemar IBARRA-ESCAMILLA Antonio BARCELATA-PINZON Evgeny A.KUZIN Faculty of Physical-Mathematical Sciences CONACYT-Universidad Autonoma de Nuevo LeonSan Nicolas de los Garza 66451Mexico Faculty of Physical-Mathematical Sciences Universidad Autonoma de Nuevo LednSan Nicolas de los Garza 66451 Mexico Optics department CONA CYT-Instituto Nacional de AstrofisieaOptica y EleetronieaTonantzintla 72480Mexico Optics department Instituto Nacional de AstrofisicaOptica y ElectronicaTonantzintla 72480Mexico Mechatronics division Universidad Tecnologica de PueblaPuebla 72300Mexico

A simple method for the estimation of the wavelength of a fiber laser system is proposed. The method is based on the use of a high-birefringence-fiber loop mirror(HBFLM).The HBFLM exhibits a periodic transmission/reflection spectrum whose spectral characteristics are determined by the length and temperature of the high-birefringence fiber(HBF).Then,by the previous characterization of the HBFLM spectral transmission response,the central wavelength of the generated laser line can be estimated.By using a photodetector,the wav.elength of the laser line is estimated during an HBF temperature scanning by measuring the temperature at which the maximum transmitted power of the HBFLM is reached.The proposed method is demonstrated in a linear cavity tunable Er/Yb fiber laser.This method is a reliable and low-cost alternative for laser wavelength determination in short wavelength ranges without the use of specialized and expensive equipment.

关键词： Wavelength meter fiber lasers fiber optical loop mirror high-birefringence fiber

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Gene Therapy of Cancer:Induction of Anti-Tumor Immunity

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Cellular & Molecular Immunology 2004年第2期1卷 105-111页

作者： Jesus prieto Division

Many malignancies lack satisfactory treatment and new therapeutic options are urgently needed.Gene therapy is a new modality to treat both inherited and acquired diseases based on the transfer of genetic material to the tissues.Different gene therapy strategies against cancers have been developed.A considerable number of preclinical studies indicate that a great variety of cancers are amenable to gene therapy.Among these strategies, induction of anti-tumor immunity is the most promising approach.Gene therapy with cytokines has reached unprecedented success in preclinical models of cancer.Synergistic rather than additive effects have been demonstrated by combination of gene transfer of cytokines/chemokines,costimulatory molecules or adoptive cell therapy.Recent progress in vector technology and in imaging techniques allowing in vivo assessment of gene expression will facilitate the development of clinical applications of gene therapy,a procedure which may have a notorious impact in the management of cancers lacking effective treatment.Cellular & Molecular Immunology.2004;1(2):105-111.

关键词： gene therapy anti-tumor immunity cytokines costimulatory molecules dendritic cell

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