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Nature of Existence and Essence of Time in Existence

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Natural Science 2022年第5期14卷 203-216页

作者： pramod kumar Agrawal Universal Theory Research Centre Jawaharlal Nehru Marg Jaipur India

This study is based on the notion that every entity has two inseparable parts: the imperceptible existence and the perceptible body. Existence is comprised of space, time, and consciousness. These characteristics manifest in the perceptible forms of capability, activity, and awareness, respectively. The findings of this study suggest that physically (atoms), biologically (vegetation), psychologically (animals), and intellectually living entities (humans) have their own existences in the following elements: space (capability), time (activity), and consciousness (awareness). This study aims to discuss the context of time by visualizing the phenomenon in which the present penetrates the space fabric by touching consciousness and establishing self-sustaining life, termed as an entity. The second part of this study suggests that the negative and positive loops represent the future and the past in a sinusoidal wave, and the base line in between represents the continuous present. A small change occurs with each oscillation or wavelength, which increases entropy. The unit “change” occurs within one wavelength, which should be treated as the smallest unit of time. This unit may differ from the prevalent unit of time, which is measured based on duration.

关键词： Origination of Time Flow of Time Arrow of Time Essence of Time Multilevel Universe

A Hybrid Deep Learning Model for COVID-19 Prediction and Current Status of Clinical Trials Worldwide

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Computers, Materials & Continua 2021年第2期66卷 1897-1920页

作者： Shwet Ketu pramod kumar Mishra Department of Computer Science Institute of ScienceBanaras Hindu UniversityVaranasiIndia

Infections or virus-based diseases are a significant threat to human societies and could affect the whole world within a very short *** Virus Disease-2019(COVID-19),also known as novel coronavirus or SARSCoV-2(Severe Acute Respiratory Syndrome-Coronavirus-2),is a respiratory based touch contiguous *** catastrophic situation resulting from the COVID-19 pandemic posed a serious threat to societies *** whole world is making tremendous efforts to combat this life-threatening *** taking remedial action and planning preventive measures on time,there is an urgent need for efficient prediction models to confront the COVID-19 outbreak.A deep learning-based ARIMA-LStm hybrid model is proposed in this article for predicting the COVID-19 outbreak by utilizing real-time information from the WHO’s daily bulletin report as well as provides information regarding clinical trials across the *** evaluate the suitability and performance of our proposed model compared to other well-established prediction models,an experimental study has been *** estimate the prediction results,the three performance measures,i.e.,Root Mean Square Error(RMSE),Coefficient of determination(R2 Score),and Mean Absolute Percentage Error(MAPE)have been *** prediction results of fifty countries substantiated the fact that the proposed ARIMA-LStm hybrid model performs very well as compared to other *** proposed model archives the lowest RMSE,lowest MAPE,and highest R2 Score throughout the testing,under varied selection criteria(country-wise).This article aims to contribute a deep learning-based solution for the wellbeing of livings and to provide the current status of clinical trials across the globe.

关键词： COVID-19 deep learning prediction clinical trials healthcare

Biochemical changes associated with flowering in Bambusa arundinacea and Bambusa nutans

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Journal of Forestry Research 2018年第5期29卷 1315-1320页

作者： pramod kumar Yogeshwar Mishra Tropical Forest Research Institute Jabalpur Madhya Pradesh 482021 India

Biochemical changes associated with flowering in Bambusa arundinacea Linn and Bambusa nutans *** Munro were *** flowering was initiated in natural areas and plantations of *** in late 2014 and reached full bloom in early 2015,whereas sporadic flowering recorded during 2014–2015 in vegetatively propagated plants of *** and nodal shoot samples from flowering culms/shoots and nonflowering culms/shoots were collected in February 2015 at the initiation of fruit filling,then analyzed and compared for soluble sugars,phenols and peroxidase *** both species sugars were higher in leaves of flowering culms/shoots and lower in nodal shoots of flowering culms/shoots compared to the *** were lower in leaves and nodal shoots of flowering ***,but higher in leaves and decreases in nodal shoots of *** activity increases in leaves and nodal shoots of *** after flowering but increases in nodal shoots and decreases in leaves of ***.

关键词： Sugars Phenols Peroxidase activity Flowering Bambusa arundinacea Bambusa nutans

Fatal Cardiac Tamponade following Road Traffic Accident

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Journal of Forensic Science and Medicine 2023年第1期9卷 88-90页

作者： G.N.pramod kumar Smitha Rani Shankar M.Bakkannavar Department of Forensic Medicine and Toxicology Karwar Institute of Medical SciencesKarwar Department of Forensic Medicine and Toxicology JSS Medical CollegeJSS Academy of Higher Education and ResearchMysore Department of Forensic Medicine and Toxicology Kasturba Medical CollegeManipal Academy of Higher EducationManipalKarnatakaIndia

Cardiac tamponade following blunt trauma results from cardiac rupture,leading to death even before the patient can receive medical *** such cases,the collected fluid(blood)in the pericardium inhibits the diastolic filling compressing the myocardium resulting in obstructive *** are reporting the case report of a 30-year-old male who was brought dead to the hospital with a history of road traffic *** investigating officer informed that the deceased driver was not wearing a seat *** findings showed fresh blood clots of 600 g in the pericardial sac with rupture of the left ventricular wall of the *** were contusions on the anterior aspect of the vertebrae corresponding to the heart *** it is impossible to prevent all the cases of cardiac tamponade,we can avoid the ones resulting from *** case intends to stress the importance of wearing a seat belt while driving a car to prevent fatal injuries.

关键词： Blunt chest trauma cardiac rupture seat belt traumatic cardiac tamponade

Transcatheter interventions for severe tricuspid regurgitation:a literature review

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Journal of Geriatric Cardiology 2022年第7期19卷 539-550页

作者： pramod kumar Ponna Stephen Patin Naga Sai Shravan Turaga Dominika M Zoltowska Vishal Devarkonda Ramya Krishna Botta Yashwant Agrawal Gaurav Dhar Internal Medicine Louisiana State University Health Sciences CenterShreveportLAUSA Division of Cardiology University of Arkansas for Medical SciencesLittle RockARUSA Division of Cardiology University of FloridaJacksonvilleFLUSA Division of Infectious Diseases Vanderbilt University Medical CenterNashvilleTNUSA Division of Cardiology Chandler Region Medical CenterChandlerArizonaUSA

The prevalence of tricuspid regurgitation(TR)increases with age,affecting 65%-85%of *** TR is caused by a congenital or acquired abnormality of the tricuspid valve apparatus(leaflets,chordae,papillary muscles,or annulus).Secondary TR is due to insufficient coaptation from dilation of tricuspid valve annulus due to the right ventricle(RV)or right at-rium(RA)remodeling and increased RV *** TR is without increased RV pressures and is associated with atrial *** TR is a benign *** to severe tricuspid regurgitation has independently been associated with in-creased *** of these patients are treated medically due to poor outcomes with surgical repair of isolated *** in-hospital mortality rate is 8.8%,and the median length of stay in hospital is 11 days resulting in higher healthcare *** if the patients undergo surgical repair or replacement,available data do not show improvement in *** a more detailed un-derstanding of the complex anatomy and physiology of the tricuspid valve and significant complications from untreated tricusp-id valve disease,the approach to the management of TR has shifted from a conservative approach to a process of prevention and *** the past decade,transcatheter tricuspid valve interventions and tricuspid annuloplasty rings have been de-veloped,contributing to decreased mortality from surgical *** tricuspid valve intervention techniques have im-proved survival,quality of life,and reduced heart failure *** review summarizes normal anatomy,types of TR,etiology and different mechanisms of TR,echocardiographic assessment of the severe TR,and highlights various percu-taneous transcatheter techniques for tricuspid valve repair.

关键词： anatomy tricuspid regurgitation

MOLECULAR DYNAMICS SIMULATION OF POLYMER/CARBON NANOTUBE COMPOSITES

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Acta Mechanica Solida Sinica 2015年第4期28卷 409-419页

作者： Sumit Sharma Rakesh Chandra pramod kumar Navin kumar Department of Mechanical Engineering Dr.B.R.Ambedkar National Institute of Technology School of Mechanical Materials & Energy Engineering (SMMEE) Indian Institute of Technology

In this paper, we present classical molecular dynamics （MD） simulations of model polymer/CNT composites constructed by embedding a single wall （10,10） CNT into two different amorphous polymer matrices： poly（methyl methacrylate） and poly{（m-phenylene-vinylene）-co- [（2,5-dioctoxy-p-phenylene） vinylene]}, respectively, with different volume fractions. The simulation results support the idea that it is possible to use CNTs to mechanically reinforce an appropri- ate polymer matrix, especially in the longitudinal direction of the nanotube. The comparison of the simulation results with the macroscopic rule-of-mixtures for composite systems showed that for strong interfacial interactions, there can be large deviations of the results from the rule-of- mixtures. In order to verify this study, results obtained have been compared with those given by Elliott and Han （2007）.

关键词： nano-structures elasticity mechanical properties computational modeling

Habitat Range of two Alpine Medicinal Plants in a Trans-Himalayan Dry Valley,Central Nepal

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Journal of Mountain Science 2009年第1期6卷 66-77页

作者： Bharat Babu SHRESTHA pramod kumar JHA Central Department of Botany Tribhuvan UniversityKathmanduNepal

Understanding of the habitat range of threatened Himalayan medicinal plants which are declining in their abundance due to high anthropogenic disturbances is essential for developing conservation strategies and agro-technologies for *** this communication, we have discussed the habitat range of two alpine medicinal plants, Aconitum naviculare(Brühl) Stapf and Neopicrorhiza scrophulariiflora(Pennel) Hong in a trans-Himalayan dry valley of central Nepal, Manang *** are the most prioritized medicinal plants of the study area in terms of ethnomedicinal *** occurs on warm and dry south facing slopes between 4090～4650 m asl along with sclerophyllous and thorny alpine scrubs, while *** is exclusively found on cool and moist north facing slope between 4000 and 4400 m asl where adequate water is available from snow melt to create a suitable habitat for this wetland dependent *** soil in rooting zone of the two plants differs significantly in organic carbon(OC), organic matter(OM), total nitrogen(N) and carbon to nitrogen(C/N) *** to cool and moist condition of *** habitat, accumulation of soil OC is higher, but soil N content is lower probably due to slow release from litter, higher leaching loss and greater retention in perennial live biomass of the *** C/N ratio of soil is more suitable in *** habitat than that of N scrophulariiflora for N *** and sunny site with N rich soil can be suitable for cultivation of ***, while moist and cool site with organic soil for *** populations of both the plants are fragmented and *** to collection by human and tramplingdamage by livestock, the population of *** was found absent in open areas in five of the six sampling sites and it was confined only within the bushes of alpine *** ***, high probability of complete receding of small glaciers may be a new threat in future t

关键词：药用植物喜马拉雅干旱河谷尼泊尔高山生境中央联合国人居署

A phase II study of neoadjuvant chemotherapy followed by organ preservation in patients with muscle-invasive bladder cancer

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Asian Journal of Urology 2022年第3期9卷 318-328页

作者： Chinna Babu Dracham Narendra kumar Santosh kumar Arun Elangovan Budhi Singh Yadav Ravimohan S.Mavuduru Anupam Lal pramod K.Gupta Rakesh Kapoor Department of Radiotherapy&Oncology PGIMERChandigarhIndia Department of Urology PGIMERChandigarhIndia Department of Radiodiagnosis PGIMERChandigarhIndia Department of Biostatistics PGIMERChandigarhIndia

Objective:Conservative approaches in muscle-invasive bladder cancer(MIBC)have been evolved to avoid aggressive surgery,but are limited to elderly,frail,and patients medically unfit for *** study aimed to assess the response rate of neoadjuvant chemotherapy(NACT)before radiotherapy(RT)in MIBC ***:Forty patients with urothelial carcinoma of stage T2-T4a,N0,M0 were enrolled between November 2013 and November 2015,and treated with three cycles of NACT with ***-NACT response was assessed using Response Evaluation Criteria in Solid Tumors(RECIST)*** who achieved complete response(CR)and partial response(PR)>50%were treated with radical RT,and those who had PR50%or CR,and were treated with ***(12.5%)patients who had PRtment regimen in carefully selected patients may omit the need for morbid surgery.

关键词： Bladder preservation Neoadjuvant chemotherapy Radiotherapy Muscle-invasive bladder cancer

Role of limited access dressing in achieving improved aesthetic results during resurfacing of wounds

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Plastic and Aesthetic Research 2020年第5期7卷 57-62页

作者： pramod kumar Department of Plastic surgery King Fahad Central HospitalJazan 82666Saudi Arabia

With refinement and better understanding of Plastic Surgery,there is increasing expectation of aesthetic outcomes after resurfacing of *** major problems in resurfacing procedures are tissue bulk,donor site issues,excessive scarring and distal edema due to damaged lymphatics and veins after flap harvest from adjacent areas in the ***-conservative debridement simplifies reconstruction by reducing the need for flaps and improves the chances of skin graft take through limited access dressing,which can improve the final aesthetic result following *** this paper,we describe three representative cases treated under limited access dressing.

关键词： Aesthetic reconstruction limited access dressing LAD