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A review on re-emerging bacteriophage therapy in the era of XDR

生物细胞(英文) 2023年第9期47卷 1915-1930页

作者： pooja bhadoriya RICHA SHARMA REKHA MEHROTRA SIMRAN KAUR ISHA SRIVASTAVA MUKUL JAIN PRASHANT KAUSHIK Department of Microbiology Shaheed Rajguru College of Applied Sciences for WomenUniversity of DelhiVasundhara EnclaveNew Delhi110096India Lab-209 Cell&Developmental biology labCenter of Research for DevelopmentParul UniversityVadodara391760GujaratIndia Instituto de Conservacióny Mejora de la Agrodiversidad Valenciana Universitat Politècnica de ValènciaValencia46022Spain

In the present medicine world antibiotic resistance is one of the key threats to universal health *** continue to work hard to combat this global health *** therapy,an age-old practice during the early twentieth century,was outshined by the discovery of *** the advent of widespread antibiotic resistance,phage therapy has again redeemed itself as a potential alternative owing to its adeptness to target bacteria *** side effects,the ability to migrate to different body organs,a distinct mode of action,and proliferation at the infection site,make phages a profitable candidate to replace conventional *** progressive outcome of numerous in vitro studies and case reports has validated the clinical efficacy of phage *** bright perspective of using phages to treat bacterial infections has fueled enormous medical research to exploit their potential as *** gaps in the information about phages and the lack of consent for clinical trials is major hurdle for consideration of phage *** phage therapy as a reality in medicine requires a coordinated effort from different *** this review,we aim to emphasize the importance of phage therapy in modern *** review explains their historical journey,basic phage biology,cross-talk with the host immunity,obstacles with phage therapy,and their possible *** data on the various significant clinical trials of phage therapy has been *** evaluated the efficacy of antibiotics and phage therapy in part and in combination,along with recent progress and future perspectives of phage therapy.

关键词： Bacteriophages Antibiotic resistance Phage biology Phage therapy Phage therapy clinical trials Phage therapy in India

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Active and passive modulation of solar light transmittance in a uniquely multifunctional dual-band single molecule for smart window applications

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Journal of Energy Chemistry 2024年第1期88卷 293-305,I0007页

作者： pooja V.Chavan Pramod V.Rathod Joohyung Lee Sergei V.Kostjuk Hern Kim Department of Energy Science and Technology Environmental Waste Recycle InstituteMyongji UniversityYonginGyeonggi-do 17058Republic of Korea Department of Chemical Engineering Myongji UniversityYonginGyeonggi-do 17058Republic of Korea Research Institute for Physical Chemical Problems of the Belarusian State University MinskBelarus

Functional materials may change color by heat and electricity separately or simultaneously in smart *** materials have not only demonstrated remarkable potential in the modulation of solar radiation but are also leading to the development of indoor environments that are more comfortable and conducive to improving individuals'quality of ***,dual-responsive materials have not received ample research attention due to economic and technological *** a consequence,the broader utilization of smart windows faces *** address this new generational multistimulus responsive chromic materials,our group has adopted a developmental strategy to create a poly(NIPAM)n-HV as a switchable material by anchoring active viologen(HV)onto a phase-changing poly(NIPAM)n-based smart material for better utility and *** constructed smart windows facilitate individualistic reversible switching,from a highly transparent state to an opaque state(thermochromic)and a red state(electrochromic),as well as facilitate a simultaneous dual-stimuli response reversible switching from a clear transparent state to a fully opaque(thermochromic)and orange(electrochromic)*** privacy can be attained in smart windows designed for exclusive settings by achieving zero *** unique chromic mode operates independently and modulates visible and near-infrared(NIR)light in a distinct ***,these smart windows with thermal and electric dual-stimuli responsiveness demonstrate remarkable heat regulation capabilities,rendering them highly attractive for applications in building facades,energy harvesting,privacy protection,and color display.

关键词： Smart windows Thermochromism Electrochromism Energy saving Dual-responsive material

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Mapping COVID-19 in India:Southern states at the forefront of new JN.1 variant

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Asian Pacific Journal of Tropical Medicine 2024年第1期17卷 1-3页

作者： Rabin Debnath Arshdeep Singh Kushal Seni Anjali Sharma Viney Chawla pooja A Chawla Department of Pharmaceutical Chemistry ISF College of PharmacyG.T RoadGhal KalanMogaPunjab142001India Department of Pharmaceutical Analysis ISF College of PharmacyG.T RoadGhal KalanMogaPunjab142001India University Institute of Pharmaceutical Sciences and Research Baba Farid University of Health SciencesFaridkotPunjabIndia

A new variant,JN.1,stemming from the omicron subvariant BA.2.86,garnered the attention of the World Health Organization(WHO)as a"variant of interest."Despite its rapid global spread,especially in the US,Canada,France,Singapore,Sweden[1],and the UK,JN.1 is considered to pose minimal *** vaccinations are believed to remain effective against *** WHO underscores the importance of maintaining immunization records amid co-occurring respiratory illnesses,and epidemiologists recommend monitoring hospitalizations,particularly in areas with low vaccination rates.

关键词： Canada Mapping spite

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Prediction of Geopolymer Concrete Compressive Strength Using Convolutional Neural Networks

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Computer Modeling in Engineering & Sciences 2024年第5期139卷 1455-1486页

作者： Kolli Ramujee pooja Sadula Golla Madhu Sandeep Kautish Abdulaziz S.Almazyad Guojiang Xiong Ali Wagdy Mohamed Department of Civil Engineering VNR Vignana Jyothi Institute of Engineering and TechnologyHyderabadTelangana500090India Department of Information Technology VNR Vignana Jyothi Institute of Engineering and TechnologyHyderabadTelangana500090India Department of Computer Science LBEF Campus(Asia Pacific University of Technology&InnovationMalaysia)Kathmandu44600Nepal Department of Computer Engineering College of Computer and Information SciencesKing Saud UniversityP.O.Box 51178Riyadh11543Saudi Arabia Guizhou Key Laboratory of Intelligent Technology in Power System College of Electrical EngineeringGuizhou UniversityGuiyang550025China Operations Research Department Faculty of Graduate Studies for Statistical ResearchCairo UniversityGiza12613Egypt Applied Science Research Center Applied Science Private UniversityAmmanJordan

Geopolymer concrete emerges as a promising avenue for sustainable development and offers an effective solution to environmental *** attributes as a non-toxic,low-carbon,and economical substitute for conventional cement concrete,coupled with its elevated compressive strength and reduced shrinkage properties,position it as a pivotal material for diverse applications spanning from architectural structures to transportation *** this context,this study sets out the task of using machine learning(ML)algorithms to increase the accuracy and interpretability of predicting the compressive strength of geopolymer concrete in the civil engineering *** achieve this goal,a new approach using convolutional neural networks(CNNs)has been *** study focuses on creating a comprehensive dataset consisting of compositional and strength parameters of 162 geopolymer concrete mixes,all containing Class F fly *** selection of optimal input parameters is guided by two distinct *** first criterion leverages insights garnered from previous research on the influence of individual features on compressive *** second criterion scrutinizes the impact of these features within the model’s predictive *** to enhancing the CNN model’s performance is the meticulous determination of the optimal *** a systematic trial-and-error process,the study ascertains the ideal number of epochs for data division and the optimal value of k for k-fold cross-validation—a technique vital to the model’s *** model’s predictive prowess is rigorously assessed via a suite of performance metrics and comprehensive score ***,the model’s adaptability is gauged by integrating a secondary dataset into its predictive framework,facilitating a comparative evaluation against conventional prediction *** unravel the intricacies of the CNN model’s learning trajectory,a loss plot is deployed to elucidate its learning rat

关键词： Class F fly ash compressive strength geopolymer concrete prediction deep learning convolutional neural network

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Recent progress in carbonaceous materials based Z-scheme and Sscheme heterojunctions for photocatalytic clean energy generation

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新型炭材料(中英文) 2024年

作者： Sahil Rana Amit Kumar Wang Tong-tong Gaurav Sharma pooja Dhiman Alberto García-Penas Interdisciplinary and Innovate Research Xi'an University of Architecture and Technology Departamento de Ciencia e Ingeniería de Materiales e Ingeniería Química (IAAB) Universidad Carlos III de Madrid International Research Centre of Nanotechnology for Himalayan Sustainability (IRCNHS) Shoolini University

Carbonaceous materials including carbon nanotubes/nanofibers, graphene, graphene oxide, reduced graphene oxide,graphyne, graphdiyne, carbon quantum dots and fullerenes have gained considerable attention in the recent years for their unique properties such as high conductivity, excellent stability and biocompatibility. The integration of these carbonaceous materials into Zscheme and S-scheme heterojunctions has emerged as a transformative strategy to enhance the photocatalytic efficiency for energy conversion applications. This review delves into the fundamental principles of clean energy generation such as photocatalytic H2generation and CO2reduction, elucidating their respective mechanisms and advantages. Furthermore, various types of carbonaceous materials, their synthesis and construction of Z-scheme and S-scheme heterojunctions are discussed emphasizing their role in promoting charge separation, reducing recombination losses and extending the spectral response range. With the focus on solar fuel production,the recent advancements in carbonaceous based Z-scheme and S-scheme heterojunctions are discussed and summarized for photocatalytic H2generation and CO2reduction. Lastly, the current bottlenecks and challenges in the field of carbonaceous based photocatalysts are discussed with the valuable insights for future development in this particular field.

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石墨炔:一种用于合成水污染物有效吸附剂的新型炭材料

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新型炭材料（中英文） 2024年第2期39卷 173-200页

作者： Gaurav Sharma Yaksha Verma Amit Kumar pooja Dhiman WANG Tong-tong Florian JStadler 深圳大学材料科学与工程学院深圳市高分子科学与技术重点实验室广东省功能材料界面工程研究中心南山区生物高分子与安全性评价重点实验室广东深圳518055 International Research Centre of Nanotechnology for Himalayan Sustainability(IRCNHS) Shoolini UniversityHimachal Pradesh 173229India 西安建筑科技大学跨学科与创新研究院陕西西安710055

石墨炔(GDY)是一种新生的二维材料,其在去除水溶液中污染物的研究方面引起了广泛关注。GDY是sp和sp2杂化碳原子的框架,其在二维对称网络中存在苯环和二乙基键,因此具有优异的共轭性、独特的可调谐电子性能、以及优异的化学和热稳定性。... 详细信息

石墨炔(GDY)是一种新生的二维材料,其在去除水溶液中污染物的研究方面引起了广泛关注。GDY是sp和sp2杂化碳原子的框架,其在二维对称网络中存在苯环和二乙基键,因此具有优异的共轭性、独特的可调谐电子性能、以及优异的化学和热稳定性。GDY的分子中有C≡C键,且具有均匀分布的三角形孔,可提供更多的反应位点和多种反应路径。因而,GDY具有吸附性,其作为吸附剂时在去除污染水中的油、有机污染物、染料和金属方面表现优异。在已发表的文献中,GDY被用作吸附剂的报道十分有限。本文综述了GDY的合成方法、GDY作为吸附剂的应用以及GDY基吸附剂的表征,并展望了GDY在污染物修复中的应用前景。

关键词：石墨炔合成吸附污染物合理机制

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碳基材料的Z型和S型异质结光催化清洁能源综述

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新型炭材料（中英文） 2024年第3期39卷 458-482页

作者： Sahil Rana Amit Kumar WANG Tong-tong Gaurav Sharma pooja Dhiman Alberto García-Penas International Research Centre of Nanotechnology for Himalayan Sustainability(IRCNHS) Shoolini UniversitySolan173229India 西安建筑科技大学交叉创新研究院西安710055 Departamento de Ciencia e Ingeniería de Materiales e Ingeniería Química(IAAB) Universidad Carlos Ⅲ de MadridLegan'es28911Spain

碳纳米管/纳米纤维、石墨烯、氧化石墨烯、还原氧化石墨烯、石墨炔、碳量子点和富勒烯等炭材料因具有高导电性、优异的稳定性和生物相容性等独特性能,近年来受到广泛关注。在炭材料中构建Z型和S型异质结已成为在能量转换应用中提高光催... 详细信息

碳纳米管/纳米纤维、石墨烯、氧化石墨烯、还原氧化石墨烯、石墨炔、碳量子点和富勒烯等炭材料因具有高导电性、优异的稳定性和生物相容性等独特性能,近年来受到广泛关注。在炭材料中构建Z型和S型异质结已成为在能量转换应用中提高光催化效率的一种有效策略。本文综述了光催化制氢和CO_(2)还原等清洁能源的基本原理,阐述了它们各自的机理和优势。此外,还讨论了不同类型的炭材料以及其中Z型和S型异质结的合成和构建,强调了它们在促进电荷分离、减少光生载流子复合损失和扩大光谱响应范围方面的作用。以太阳能燃料生产为重点,讨论和总结了碳基Z型和S型异质结在光催化制氢和还原CO_(2)方面的最新进展。最后,讨论了目前碳基光催化剂领域的瓶颈和挑战,并对该领域的未来发展提出了有价值的见解。

关键词：炭材料异质结 Z型 S型光催化氢能材料

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Analysis of the Fertilizing and Bioremediation Potential of Leaf Litter Compost Amendment in Different Soils through Indexing Method

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Journal of Environmental Protection 2024年第3期15卷 265-297页

作者： Sophayo Mahongnao pooja Sharma Arif Ahamad Sarita Nanda Department of Biochemistry Daulat Ram College University of Delhi New Delhi India Department of Environmental Science Jamia Millia Islamia University New Delhi India

This research study explored the efficacy of leaf litter compost as a sustainable soil amendment with the objective of promoting soil health and mitigating the accumulation of potentially toxic elements. The investigation encompassed the impact of various organic compost amendments, including leaf compost, cow dung manure, kitchen waste compost, municipal organic waste compost, and vermicompost. The study employed Inductively Coupled Plasma Mass Spectrometry (ICP-MS) to evaluate soil nutrient levels and concentrations of Potentially Toxic Elements (PTEs) such as arsenic, chromium, cadmium, mercury, lead, nickel, and lithium. The fertilization and bioremediation potential of these compost amendments are quantified using an indexing method. Results indicated a substantial increase in overall nutrient levels (carbon, nitrogen, phosphorus, potassium, and sulfur) in soils treated with leaf compost and other organic composts. Fertility indices (FI) are notably higher in compost-amended soils (ranging from 2.667 to 3.938) compared to those amended with chemical fertilizers (ranging from 2.250 to 2.813) across all soil samples. Furthermore, the mean concentrations of PTEs were significantly lower in soils treated with leaf compost and other organic compost amendments compared to those treated with chemical fertilizers amendments. The assessment through the indexing method revealed a high clean index (CI) for leaf compost amendment (ranging from 3.407 to 3.58), whereas the chemical fertilizer amendment exhibits a relatively lower CI (ranging from 2.78 to 3.20). Consequently, leaf compost and other organic composts exhibit the potential to enhance sustainable productivity, promoting soil health and environmental safety by improving nutrient levels and remediating potentially toxic elements in the soil.

关键词： Bio-Compost Soil Fertility Potentially Toxic Elements Bioremediation

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To Analyze the Sensitivity of RT-PCR Assays Employing S Gene Target Failure with Whole Genome Sequencing Data during Third Wave by SARS-CoV-2 Omicron Variant

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Advances in Microbiology 2024年第5期14卷 247-255页

作者： pooja Patel Yogita Mistry Monika Patel Summaiya Mullan Viral Research and Diagnostic Laboratory Department of Microbiology Government Medical college Surat India

Introduction: Omicron is a highly divergent variant of concern (VOCs) of a severe acute respiratory syndrome SARS-CoV-2. It carries a high number of mutations in its spike protein hence;it is more transmissible in the community by immune evasion mechanisms. Due to mutation within S gene, most Omicron variants have reported S gene target failure (SGTF) with some commercially available PCR kits. Such diagnostic features can be used as markers to screen Omicron. However, Whole Genome Sequencing (WGS) is the only gold standard approach to confirm novel microorganisms at genetically level as similar mutations can also be found in other variants that are circulating at low frequencies worldwide. This Retrospective study is aimed to assess RT-PCR sensitivity in the detection of S gene target failure in comparison with whole genome sequencing to detect variants of Omicron. Methods: We have analysed retrospective data of SARS-CoV-2 positive RT-PCR samples for S gene target failure (SGTF) with TaqPath COVID-19 RT-PCR Combo Kit (ThermoFisher) and combined with sequencing technologies to study the emerged pattern of SARS-CoV-2 variants during third wave at the tertiary care centre, Surat. Results: From the first day of December 2021 till the end of February 2022, a total of 321,803 diagnostic RT-PCR tests for SARS-CoV-2 were performed, of which 20,566 positive cases were reported at our tertiary care centre with an average cumulative positivity of 6.39% over a period of three months. In the month of December 21 samples characterized by the SGTF (70/129) were suggestive of being infected by the Omicron variant and identified as Omicron (B.1.1.529 lineage) when sequence. In the month of January, we analysed a subset of samples (n = 618) with SGTF (24%) and without SGTF (76%) with Ct values Conclusions: During the COVID-19 pandemic, it took almost more than 15 days to diagnose infection and identify pathogen by sequencing technology. In contrast to that molecular assay provided qu

关键词： SARS-CoV-2 S Gene Target Failure Whole Genome Sequencing Omicron

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Physico-chemical properties of wild edible fruit Meyna laxifora Robyns(Alu):production of Alu fruit powder by using drying aid

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Journal of Future Foods 2024年第4期4卷 353-360页

作者： Rohini Vijay Dhenge Arjun Mohanakumar Suhel Bhendawade Prashant Chavhan Sagar Deshpande pooja Lade Abhijeet Gatade Akshaya kumar Sahoo Deparment of Food and Dnug.University of Parma Parma 43124.Italy Deparoment of Food Science and Technolog Shivaji UniversityKolhapurMaharashtra 416004.India

The study focuses on the physico-chemical characteritics of the wild fruit Meyna laxiflora Robyns(Alu)and fruit powder,which was gathered from the Konkan region of Maharashtra Alu fruit powder is made by using a drying aid called maltodextrin(MD).Powder samples(MP1,MP2,MP3,MP4 and MP5)were made using different amounts of MD(05,10,15,2.0 and 2.5 g).Preliminary phytochemical screening of fnuit pulp and powder showed the presence of some phytoconstituents such as reducing sugar,saponin,flavonoids,and terpenoids,whereas akaloids,tannins,steroids and protein were absent in *** parameters of the powder are durectly infuenced by the amount of MD,as evidenced by the variations in bulk density,total soluble solids,pH,specific gravity and the proximate among the powder *** solubility was found in the sample with a medium of *** highest of particle distribution was found in MD-added samples MP2(1 g),MP3(1.5 g),MP4(2 g)whereas the raw(MPO)showed the *** analysis was done using 9-point hedonic scale,which revealed that MP2,MP3,and MP4 were highly *** study assumed that fresh Alu fuit,palp and in the form of powder can be useful for the development of new products.

关键词： Meyna laxiflora Robyns Maltodextrin Solubility Particle size distribution Sensory analysis

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