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基于统计分析的混合交通间隙模型(英文)

交通运输系统工程与信息 2012年第6期12卷 72-84页

作者： DUBEY Subodh Kant ponnu balaji ARKATKAR Shriniwas S Birla技术与科学学院土木工程系印度拉贾斯坦邦皮拉尼-333031

车辆间隙定义为到达路段某特定点相邻车辆的间隔.本文研究了非双车道异质混合交通情形下的车辆间隙模型,此类交通流在诸如印度等一些发展中国家普遍存在.其特征是具有大量'零间隙'的情况,这主要由给定车道宽度下车辆同时到达的情形所致... 详细信息

车辆间隙定义为到达路段某特定点相邻车辆的间隔.本文研究了非双车道异质混合交通情形下的车辆间隙模型,此类交通流在诸如印度等一些发展中国家普遍存在.其特征是具有大量'零间隙'的情况,这主要由给定车道宽度下车辆同时到达的情形所致.其另一特征是较大车头时距带来的尾区数据量偏大.然而,一些学者运用轻尾分布对车辆间隙进行建模并得到了满意的结果.原因主要是:(1)尾区数据融入单个面元;(2)分布拟合时卡方检验等方法具有一定的局限性.此外,一些学者还建议对同一范围的交通流数据采用其他一些分布进行拟合,产生了分布选择的分歧.同时,可表征任何分布拟合状况的面元在间隙模型中的作用逐渐减小.因此,本文就以上问题对现有间隙模型的研究进行进一步和标准化的分析.本文还分析了两种具有较好尾模型特性的广义Pareto分布(GP)、广义极值分布(GEV)、其他几种传统分布对550 vph至4 100 vph流量范围内车辆间隙建模,且使用基于区域和基于距离检验的方法进行分布拟合检验.结果表明,无论使用哪种检验方法,广义Pareto分布对于大于1 500 vph流量的间隙数据在整体和尾区均能得到较好的拟合效果.广义极值分布在使用基于区域的检验方法时对于大于1 500 vph流量的间隙数据产生较好的拟合效果.

关键词：公路运输车辆间隙异质交通流面元大小 K-S检验 A-D检验

Does topical vancomycin prevent fracture-related infections in closed fractures undergoing open reduction and internal fixation?A randomised controlled trial

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Chinese Journal of Traumatology 2024年第2期27卷 71-76页

作者： Mohit Gandhi Gopisankar balaji Jagdish Menon Ruben Raj Thomas Department of Orthopaedics Jawaharlal Institute of Postgraduate Medical Education and ResearchPondicherryIndia Department of Preventive and Social Medicine Jawaharlal Institute of Postgraduate Medical Education and ResearchPondicherryIndia

Purpose:The role of topical vancomycin in fracture-related infection(FRI)is *** few studies have reported their efficacy in open and high-risk extremity *** study aimed to assess topical vancomycin's role in reducing FRI in closed fractures undergoing open surgical intervention with an ***:This prospective randomized cohort study was carried out between February 2021 to January *** with isolated closed fractures,who were planned for open reduction and internal fixation within 2 weeks from the time of injury were included for this *** data collected included age,gender,socioeconomic status,mechanism of injury,diagnosis,Tscherne classification,and time interval to take up for *** were randomized into the intervention and control groups using the block randomization *** control group received only systemic antibiotic prophylaxis,whereas the intervention group received topical application of vancomycin powder in the surgical wound alongside systemic antibiotic *** primary outcome measure was the incidence of FRI among these *** and radiological findings and culture reports(in cases with infection)were recorded during the post-operative period and at 6 weeks of *** relevant statistical calculations were done using STATA statistical/data analysis-parallel edition version 16.0(StataCorp LLC).The quantitative variables like age and duration of the surgery were assessed for normalcy by Shapiro-Wilk W *** independent samples t-test with equal variances was applied to the age ***'s exact test was used for the analysis of the primary outcome measure(presence of FRI following surgery),and"Risk of FRI"and"Risk difference"between the 2 groups was *** strength of the association between qualitative variables was assessed using the Fisher's exact and Chi-square tests,***:There were 88 patients included in this *** statistical si

关键词： Infections Antibiotics Vancomycin Fractures

Integrating Transformer and Bidirectional Long Short-Term Memory for Intelligent Breast Cancer Detection from Histopathology Biopsy Images

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Computer Modeling in Engineering & Sciences 2024年第10期141卷 443-458页

作者： Prasanalakshmi balaji Omar Alqahtani Sangita Babu Mousmi Ajay Chaurasia Shanmugapriya Prakasam Department of Computer Science College of Computer ScienceKing Khalid UniversityAbha61451Saudi Arabia College of Science and Arts in Rijal Alma King Khalid UniversityAbha61451Saudi Arabia Department of Information Technology Muffakham Jah College of Engineering and TechnologyHyderabad500034India Department of Computer Science and Business Systems Rajalakshmi Engineering CollegeThandalam602105India

Breast cancer is a significant threat to the global population,affecting not only women but also a threat to the entire *** recent advancements in digital pathology,Eosin and hematoxylin images provide enhanced clarity in examiningmicroscopic features of breast tissues based on their staining *** cancer detection facilitates the quickening of the therapeutic process,thereby increasing survival *** analysis made by medical professionals,especially pathologists,is time-consuming and challenging,and there arises a need for automated breast cancer detection *** upcoming artificial intelligence platforms,especially deep learning models,play an important role in image diagnosis and ***,the histopathology biopsy images are taken from standard data ***,the gathered images are given as input to the Multi-Scale Dilated Vision Transformer,where the essential features are ***,the features are subjected to the Bidirectional Long Short-Term Memory(Bi-LSTM)for classifying the breast cancer *** efficacy of the model is evaluated using divergent *** compared with other methods,the proposed work reveals that it offers impressive results for detection.

关键词： Bidirectional long short-term memory breast cancer detection feature extraction histopathology biopsy images multi-scale dilated vision transformer

不均匀海底地形影响下柔性板与斜向来浪的相互作用

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哈尔滨工程大学学报（英文版） 2024年第2期23卷 261-275页

作者： Saista Tabssum balaji Ramakrishnan School of Advanced Science-Mathematics VIT-APAmravati744101India Department of Civil Engineering Indian Institute of TechnologyBombay 400076India

The present work analyzes the interaction of oblique waves by a porous flexible breakwater in the presence of a step-type *** physical models for both scattering and trapping cases are considered and developed within the framework of small amplitude water-wave ***’s law is used to model the wave interaction with the porous *** is assumed that the varying bottom extends over a finite interval,connected by a finite length of uniform bottom near an impermeable wall,and a semi-infinite length of bottom in the open water *** boundary value problem is solved using the eigenfunction expansion method in the uniform bottom regions,while a modified mild-slope equation(MMSE)is used for the region with the varying ***,a mass-conserving jump condition is employed to handle the solution at slope discontinuities in the bottom.A system of equations is derived by matching the solutions at *** reflection coefficient and force on the breakwater and impermeable wall are plotted and analyzed for various parameters,such as the length of the varying bottom,depth ratio,angle of incidence,and flexural *** is observed that moderate values of flexural rigidity and depth ratio significantly contribute to an optimum reflection coefficient and reduce the wave force on the wall and ***,the outcomes of this study are assumed to be applicable in the construction of this type of breakwater in coastal regions.

关键词： Porous flexible breakwater Varying bottom Mild-slope equation Reflection coefficient Wave force

Downwash airflow distribution pattern of hexa-copter unmanned aerial vehicles

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International Journal of Agricultural and Biological Engineering 2024年第4期17卷 24-34页

作者： Dengeru Yallappa Ramasamy Kavitha Allimuthu Surendrakumar Kannan balaji Balakrishnan Suthakar Ayyasamy Paramasivam Mohan Kumar Yathendranaik Ravi Narayananaik Ashoka Kumar Kavan Department of Farm Machinery and Power Engineering Agricultural Engineering College and Research InstituteTamil Nadu Agricultural UniversityCoimbatore

In recent times,the use of vertical take-off and landing(VTOL)multi-rotor Unmanned Aerial Vehicle(UAVs)for spraying chemical pesticides against weeds and pests has recently become *** current aerial spray application research is primarily focused on examining the influence of UAV spraying parameters such as flight height,travel speed,rotor configuration,droplet size,payload and wind *** downwash airflow velocity generated by the UAV rotor propeller has a significant impact on the droplet deposition process.A test rig was developed to measure the downwash airflow pattern generated by the rotor propeller of a *** this investigation,a six-rotor electric autonomous UAV sprayer was used to investigate the parameters and distribution laws of downwash airflow *** downwash airflow velocity was measured using portable anemometers mounted on the test rig at radial positions viz.,0 m,0.5 m,1 m,1.5 m and 2 m,perpendicular to(X)and parallel to the UAV’s flight direction(Y).The experiment was conducted at three levels of hover height,viz.,1 m,2 m and 3 m(Z)and three levels of payload,viz.,0 kg,5 kg,and 10 *** special downwash airflow distribution pattern was analysed using the Python programming language(Version 3.7).Results show that the downwash airflow velocity generated by the radial position of the UAV rotor is evenly distributed on the rotating loop and the standard deviation of the downwash airflow velocity is less than 0.5 m/*** maximum downwash airflow velocity of 13.8 m/s was observed below the rotor at 10 kg payload capacity,1 m hover height(Z),and 0.5 m in the *** minimum downwash wind field of 0.3 m/s was observed at 0 kg pay load capacity,1 m height,and 2 m in the *** downwash airflow velocity along each position in the radial direction of the rotor increases initially and then *** downwash airflow distribution results helps in mounting of spray nozzle configuration to drone sprayer which helps to

关键词： downwash air payload rotor propeller flight height distribution analysis flight direction

Endoscopic full-thickness plication along with argon plasma coagulation for treatment of proton pump inhibitor dependent gastroesophageal reflux disease

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World Journal of Gastrointestinal Endoscopy 2024年第5期16卷 250-258页

作者： Yogesh Harwani Shreya Butala balaji More Varun Shukla Anand Patel Department of Gastroenterology Nobel Gastro HospitalAhmedabad 408409GujaratIndia Department of Gastroenterology Sanjay Gandhi Post Graduate Institute of Medical SciencesLucknow 226014Uttar PradeshIndia Department of Pharmacology Mahatma Gandhi Medical College and Research InstitutePuducherry 607402PuducherryIndia Department of Gastroenterology Noble Institute of GastroenterologyAhmedabad 380009GujratIndia

BACKGROUND Most endoscopic anti-reflux interventions for gastroesophageal reflux disease(GERD)management are technically challenging to practice with inadequate data to support it ***,this study was carried to evaluate the effectiveness and safety newer endoscopic full-thickness fundoplication(EFTP)device along with Argon Plasma Coagulation to treat individuals with *** To evaluate the effectiveness and safety newer EFTP device along with Argon Plasma Coagulation to treat individuals with *** This study was a single-center comparative analysis conducted on patients treated at a Noble Institute of Gastroenterology,Ahmedabad,hospital between 2020 and *** research aimed to retrospectively analyze patient data on GERD symptoms and proton pump inhibitor(PPI)dependence who underwent EFTP using the GERD-X system along with argon plasma coagulation(APC).The primary endpoint was the mean change in the total gastroesophageal reflux disease health-related quality of life(GERD-HRQL)score compared to the baseline measurement at the 3-month *** endpoints encompassed enhancements in the overall GERD-HRQL score,improvements in GERD symptom scores at the 3 and changes in PPI usage at the 3 and 12-month time *** In this study,patients most were in Hill Class II,and over half had ineffective esophageal *** the EFTP procedure,there were significant improvements in heartburn and regurgitation scores,as well as GERDHRQL scores(P<0.001).PPI use significantly decreased,with 82.6%not needing PPIs or prokinetics at end of 1 *** significant adverse events related to the procedures were observed in either *** The EFTP along with APC procedure shows promise in addressing GERD symptoms and improving patients'quality of life,particularly for suitable ***,the application of a lone clip with APC yielded superior outcomes and exhibited greater cost-effectiveness.

关键词： Gastroesophageal reflux disease Endoscopy Quality of life Endoscopic antireflux interventions Retrospective data analysis Gastroesophageal reflux disease symptom scores Proton pump inhibitor

Biological,pathological,and multifaceted therapeutic functions of exosomes to target cancer

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Oncology Research 2024年第1期32卷 73-94页

作者： VIGNESH balaji E DIVYA RAMESH MANISHA CHUNGAN SHAJU AKSHARA KUMAR SAMYAK PANDEY RAKSHA NAYAK V.ALKA SRISHTI MUNJAL AMIR SALIMI K.SREEDHARA RANGANATH PAI SHANKAR M.BAKKANNAVAR Department of Pharmacology Manipal College of Pharmaceutical SciencesManipal Academy of Higher EducationManipalKarnataka576104India Department of Forensic Medicine and Toxicology Kasturba Medical CollegeManipal Academy of Higher EducationManipalKarnataka576104India School of Health and Community Services Durham CollegeOshawaOntarioL1G2G5Canada Department of Pharmaceutical Regulatory Affairs and Management Manipal College of Pharmaceutical SciencesManipal Academy of Higher EducationManipalKarnataka576104India Department of Clinical Psychology Manipal College of Health ProfessionsManipal Academy of Higher EducationManipalKarnataka576104India Department of Speech and Hearing Manipal College of Health ProfessionsManipal Academy of Higher EducationManipalKarnataka576104India Department of Pharmacy Practice Manipal College of Pharmaceutical SciencesManipal Academy of Higher EducationManipalKarnataka576104India

Exosomes,small tiny vesicle contains a large number of intracellular particles that employ to cause various diseases and prevent several pathological events as well in the human *** is considered a“double-edged sword”,and depending on its biological source,the action of exosomes varies under physiological ***,the isolation and characterization of the exosomes should be performed accurately and the methodology also will vary depending on the exosome ***,the uptake of exosomes from the recipients’cells is a vital and initial step for all the physiological *** are different mechanisms present in the exosomes’cellular uptake to deliver their cargo to acceptor *** the exosomal uptake takes place,it releases the intracellular particles that leads to activate the physiological *** though exosomes have lavish functions,there are some challenges associated with every step of their preparation to bring potential therapeutic ***,overcoming the pitfalls would give a desired quantity of exosomes with high purity.

关键词： Exosomes Physiology Cancer Therapeutics Challenges

Hybrid silver nanoparticles:Modes of synthesis and various biomedical applications

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Electron 2024年第2期2卷 196-218页

作者： Priyanka Singh Shivang Singh balaji Maddiboyina SaiKrishna Kandalam Tomasz Walski Raghvendra A.Bohara Centre for Interdisciplinary Research D.Y.Patil Educational SocietyKolhapurIndia Department of Internal Medicine Rauta Hospital Pvt.LtdGaighatUdayapurNepal Department of Medical and Scientific Communications Scientific Writing ServicesFreyr Global Regulatory Solutions&ServicesHyderabadTelanganaIndia INSERM U 1066 ‘Micro et Nanomédecines Biomimétiques-MINT’AngersFrance UniversitéAngers UMR-S1066AngersFrance Department of Biomedical Engineering Wroclaw University of Science and TechnologyWroclawPoland University of Galway

In the present day,there is a growing trend of employing new strategies to synthesize hybrid nanoparticles,which involve combining various functionalities into a single nanocomposite *** modern methods differ significantly from the traditional classical approaches and have emerged at the forefront of materials *** fabrication of hybrid nanomaterials presents an unparalleled opportunity for applica-tions in a wide range of areas,including therapy to *** focus of this review article is to shed light on the different modalities of hybrid nanoparticles,providing a concise description of hybrid silver nano-particles,exploring various modes of synthesis and classification of hybrid silver nanoparticles,and highlighting their ***-tionally,we discussed core-shell silver nanoparticles and various types of core and shell combinations based on the material category,such as dielectric,metal,or *** two primary classes of hybrid silver nanoparticles were also ***,various hybrid nanoparticles and their methods of synthesis were discussed but we emphasize silica as a suitable candidate for hybridization alongside metal *** choice is due to its hydrophilic surface qualities and high surface charge,which provide the desired repulsive forces to minimize aggregation between the metal nanoparticles in the liquid *** shell encapsulation also provides chemical inertness,robustness and the adaptability to the desired hybrid ***,among all the materials used to coat metal nanoparticles;silica is highly approved.

关键词： biomedical applications hybrid silver nanoparticles polyvinylpyrrolidone silica shell surface enhanced Raman spectroscopy

Comparative evaluation of artificial intelligence systems'accuracy in providing medical drug dosages:A methodological study

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World Journal of Methodology 2024年第4期14卷 121-130页

作者： Swaminathan Ramasubramanian Sangeetha balaji Tejashri Kannan Naveen Jeyaraman Shilpa Sharma Filippo Migliorini Suhasini Balasubramaniam Madhan Jeyaraman Department of Orthopaedics Government Medical CollegeOmandurar Government EstateChennai 600002Tamil NaduIndia Department of Orthopaedics ACS Medical College and HospitalDr MGR Educational and Research InstituteChennai 600077Tamil NaduIndia Department of Paediatric Surgery All India Institute of Medical SciencesNew Delhi 110029India Department of Life Sciences HealthLink Campus UniversityRome 00165Italy Department of Orthopaedic and Trauma Surgery Academic Hospital of Bolzano(SABES-ASDAA)Teaching Hospital of the Paracelsus Medical UniversityBolzano 39100Italy Department of Radio-Diagnosis Government Stanley Medical College and HospitalChennai 600001Tamil NaduIndia

BACKGROUND Medication errors,especially in dosage calculation,pose risks in *** intelligence(AI)systems like ChatGPT and Google Bard may help reduce errors,but their accuracy in providing medication information remains to be *** To evaluate the accuracy of AI systems(ChatGPT 3.5,ChatGPT 4,Google Bard)in providing drug dosage information per Harrison's Principles of Internal *** A set of natural language queries mimicking real-world medical dosage inquiries was presented to the AI *** were analyzed using a 3-point Likert *** analysis,conducted with Python and its libraries,focused on basic statistics,overall system accuracy,and disease-specific and organ system *** ChatGPT 4 outperformed the other systems,showing the highest rate of correct responses(83.77%)and the best overall weighted accuracy(0.6775).Disease-specific accuracy varied notably across systems,with some diseases being accurately recognized,while others demonstrated significant *** system accuracy also showed variable results,underscoring system-specific strengths and *** ChatGPT 4 demonstrates superior reliability in medical dosage information,yet variations across diseases emphasize the need for ongoing *** results highlight AI's potential in aiding healthcare professionals,urging continuous development for dependable accuracy in critical medical situations.

关键词： Dosage calculation Artificial intelligence ChatGPT Drug dosage Healthcare Large language models