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中国临床药理学杂志 2024年第8期40卷 1159-1159页

作者： plante m KWON J S FERGUSON S 王超群

回顾性资料显示,早期低危宫颈癌患者参数浸润发生率较低,这就提出了这些患者是否需要根治性子宫切除术的问题。然而,比较根治性和单纯性子宫切除术结果的大型随机试验数据缺乏。本研究进行了一项多中心、随机、非劣效性试验,比较了低危... 详细信息

回顾性资料显示,早期低危宫颈癌患者参数浸润发生率较低,这就提出了这些患者是否需要根治性子宫切除术的问题。然而,比较根治性和单纯性子宫切除术结果的大型随机试验数据缺乏。本研究进行了一项多中心、随机、非劣效性试验,比较了低危宫颈癌(病变≤2cm,间质浸润有限)患者的根治性子宫切除术和单纯性子宫切除术,包括淋巴结评估。主要结局是3年盆腔肿瘤复发(盆腔复发)。预先规定的3年盆腔复发组间差异的非劣效性界限为4个百分点。

关键词：根治性子宫切除术盆腔肿瘤回顾性资料间质浸润宫颈癌患者盆腔复发预先规定低危

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经阴道根治性子宫颈切除术术后50例妊娠分析及文献回顾:一种在早期宫颈癌治疗中保留生育力的有价值的选择

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世界核心医学期刊文摘（妇产科学分册） 2005年第11期1卷 35-36页

作者： plante m. Renaud m.-C. Hoskins I.A. Roy m. 王颖 Gynecologic Oncology Service L' Htel-Dieu de Québec Laval University 11 Cte du Palais Quebec City Que. G1R-2J6 Canada

Objective. To report the obstetrical results following vaginal radical trachelectomy (VRT), a fertility-preserving surgery in the treatment of early-stage cervical cancer. methods. Retrospective review of our first 72 patients treated by a laparoscopic pelvic lymphadenectomy followed by a VRT from October 1991 to October 2003 with regards to their reproductive function. Results. Patients’ median age was 32 years old (21-42) and 53 (74% ) were nulligravida. A total of 50 pregnancies occurred in 31 women. The majority (66% ) had only one pregnancy, 19% had 2 pregnancies and 16% had 3 pregnancies or more. The rate of first trimester miscarriage was 16% , the rate of second trimester miscarriage was (4% ) and 2 women (4% ) elected to have pregnancy termination. A total of 36 pregnancies (72% ) reached the third trimester. Of those, 3 (8% ) ended prematurely at m ( > 37 weeks). One newborn died of neonatal sepsis from E. coli infection and one died from cardiac malformation (trisomy-18). Seven patients (10% ) had infertility problems: 3 from ovulatory causes of which 2 successfully conceived with IVF, one from endometriosis and low sperm count and 3 from probable cervical cause of which one conceived with IUI. One patient had a twin pregnancy following IVF and elected to have embryo reduction and subsequently delivered at 37 weeks. Conclusion. Based on our experience, the obstetrical results following VRT for early-stage cervical cancer are very encouraging. The majority of women can anticipate to conceive spontaneously and deliver near term.

关键词：早期宫颈癌文献回顾宫颈切除术足月分娩少精症流产率妊娠晚期妊娠早期腔镜终止妊娠

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Brain Amyloidoma: Case Report and Literature Review

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Open Journal of modern Neurosurgery 2020年第4期10卷 403-421页

作者： Abd El Kader moumouni Daniel memia Zolo Essossinam Kpelao Pascal Compaore Dabou Abiba Tamou Tabe Latevi Lawson Pwerew Rodolphe plante Edem Kossi Gueouguede Benedicte Souho Abderrahmane Hamlat Department of Neurosurgery CHU Martinique Martinique France Department of Neurosurgery CHU Kara Kara Togo Department of Neurosurgery CHU Sylvanus Olympio Lomé Togo Departments of Radiology CHR Kara Kara Togo

Introduction: Primary deposition of amyloid can take several forms including amyloidoma organ restricted among which is brain. Brain amyloidoma can mimic several lesions and offers a diagnostic challenge to the physician. The present work reports an additional case and summarizes the salient characteristics of previously published cases. Case Report: A 61-year-old, woman experienced paroxystic auditory hallucinations followed at times by generalized tonico-clonic seizures. Examination revealed a mild left pyramidal weakness. Head CT scan and mRI revealed a lobular lesion of the right atrium with contrast enhancement. The diagnosis of amyloidoma Lambda light chain (λLC) type was performed by means of a stereotactic biopsy. The patient was treated by 3 cures of high dose methotrexate (15 mg/m2). At 24 months follow up the patient remains stable clinically and biologically. The 2 years follow-up mRI showed the same findings. Conclusion: No guidelines can be suggested for brain amyloidoma treatment;the “wait and see” was the mind-set in the literature. However, a non-tumour like pattern of a cerebral mass developing near the ventricle with a fine, irregular radiating margin enhancement and lack of oedema, and mass effect are important mRI clues for brain amyloidoma diagnosis. The diagnosis is histological after biopsy or excision.

关键词： Amyloidoma Brain Literature Review

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