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自主机器人使能技术在制造业中的应用（英文）

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Transactions of Nanjing University of Aeronautics and Astronautics 2024年第4期 403-431页

作者： ERD?S Gábor ABAI Kristóf BEREGI Richárd CSEMPESZ János CSERTEG Tamás GODó Gábor HAJóS Mátyás HáY Borbála HORVáTH Dániel HORVáTH Gergely JUNIKI ádám KEMéNY Zsolt KOVáCS András NACSA János PANITI Imre pedone gianfranco TAKáCS Emma TIPARY Bence ZAHORáN László VáNCZA József 匈牙利研究网络计算机科学与控制研究所布达佩斯经济与技术大学制造科学与技术系 EPIC非盈利创新实验室厄特沃什·罗兰大学

自主制造系统的研究既受益于信息物理融合系统这一新技术的推动，也响应工业实际需求的号召。目前，先进的传感器技术、数字孪生、人工智能和新型通信技术可以支持半结构化工业环境中的自主操作，可实现对生产过程的实时监控、情况识别... 详细信息

自主制造系统的研究既受益于信息物理融合系统这一新技术的推动，也响应工业实际需求的号召。目前，先进的传感器技术、数字孪生、人工智能和新型通信技术可以支持半结构化工业环境中的自主操作，可实现对生产过程的实时监控、情况识别和预测、自动和自适应（重新）规划、团队合作，以及通过学习提高性能。本文总结了实现自主工业机器人技术的主要需求，提出了实现此类系统的通用工作流程，并介绍了HUN-REN SZTAKI最近在装配、焊接、打磨、拾取和放置以及机械加工等多个应用领域的广泛实践。这些解决方案的共同点是以通用的数字孪生概念为核心。最后，本文提出实现工业自主机器人解决方案的一般建议，并讨论了未来要研究的一些开放性问题。

关键词：工业机器人自动化数字孪生使能技术

Predicting the activity of single atom catalysts

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Science China Chemistry 2024年第9期67卷 2792-2793页

作者： Giovanni Di Liberto gianfranco Pacchioni Dipartimento di Scienza dei Materiali Universitàdi Milano-Bicoccavia R.Cozzi 5520125 MilanoItaly

For a long time,the existence of single-atom catalysts(SACs),consisting of isolated atoms stabilized in a specific support,was not detected due to limitations in available characterization *** the past two decades,however,the ability to synthesize and characterize these systems has opened the way toward designing and testing a new class of potential catalysts[1].

关键词： catalysts limitations testing

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Rates, predictors, and causes of readmission after transcatheter aortic valve replacement in patients with chronic kidney disease

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World Journal of Cardiology 2024年第7期16卷 402-411页

作者： Taha Teaima gianfranco Bittar Carlini Rohan A Gajjar Imran Aziz Sami J Shoura Abdul-Rahim Shilbayeh Naim Battikh Tareq Alyousef Division of Cardiology Department of MedicineJohn H.StrogerJr.Hospital of Cook CountyChicagoIL 60612United States

BACKGROUND Transcatheter aortic valve replacement(TAVR)is a revolutionary procedure for severe aortic *** coexistence of chronic kidney disease(CKD)and TAVR introduces a challenge that significantly impacts patient *** To define readmission rates,predictors,and causes after TAVR procedure in CKD stage 1-4 *** We used the national readmission database 2018 and 2020 to look into readmission rates,causes and predictors after TAVR procedure in patients with CKD stage *** Out of 24758 who underwent TAVR and had CKD,7892(32.4%)patients were readmitted within 90 days,and had higher adjusted odds of being females(adjusted odds ratio:1.17,95%CI:1.02-1.31,P=0.02)with longer length of hospital stay>6 days,and more comorbidities including but not limited to diabetes mellitus,anemia,and congestive heart failure(CHF).CONCLUSION Most common causes of readmission included CHF(18.0%),sepsis,and complete atrioventricular *** readmission predictors with very close followup is warranted to prevent such high rate of readmission.

关键词： Chronic kidney disease Transcatheter aortic valve replacement Readmission Predictors Rates

Probiotics to counteract biofilm-associated infections: promising and conflicting data

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International Journal of Oral Science 2014年第4期6卷 189-194页

作者： Claudia Vuotto Francesca Longo gianfranco Donelli Microbial Biofilm Laboratory IRCCS Fondazione Santa Lucia Rome Italy

Altered bowel flora is currently thought to play a role in a variety of disease conditions, and the use of Bifidobacterium spp. and Lactobacillus spp. as probiotics has been demonstrated to be health-promoting, even if the success of their administration depends on the applied bacterial strain（s） and the targeted disease. In the last few decades, specific probiotics have been shown to be effective in the treatment or the prevention of acute viral gastroenteritis, pediatric post-antibiotic-associated diarrhea, some pediatric allergic disorders, necrotizing enterocolitis in preterm infants, inflammatory bowel diseases and postsurgical pouchitis. The potential application of probiotics is continuously widening, with new evidence accumulating to support their effect on the prevention and treatment of other disease conditions, including several oral diseases, such as dental caries, periodontal diseases and oral malodor, as well as genitourinary and wound infections. Considering the increasingly widespread ability of pathogens to generate persistent biofilm-related infections, an even more attractive proposal is to administer probiotics to prevent or counteract biofilm *** response of biofilm-based oral, intestinal, vaginal and wound infections to probiotics treatment will be reviewed here in light of the most recent results obtained in this field.

关键词： biofilm genitourinary tract gut infections oral cavity probiotics wounds

Bile acid signaling and biliary functions

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Acta Pharmaceutica Sinica B 2015年第2期5卷 123-128页

作者： Hannah Jones gianfranco Alpini Heather Francis Baylor Scott & White Digestive Disease Research Center Division Research Central Texas Veterans Health Care System Department of Medicine Texas A&M University

This review focuses on various components of bile acid signaling in relation to cholangiocytes. Their roles as targets for potential therapies for cholangiopathies are also explored. While many factors are involved in these complex signaling pathways, this review emphasizes the roles of transmembrane G protein coupled receptor(TGR5), farnesoid X receptor(FXR), ursodeoxycholic acid(UDCA) and the bicarbonate umbrella. Following a general background on cholangiocytes and bile acids,we will expand the review and include sections that are most recently known(within 5–7 years) regarding the field of bile acid signaling and cholangiocyte function. These findings all demonstrate that bile acids influence biliary functions which can, in turn, regulate the cholangiocyte response during pathological events.

关键词： Bile acids Cholangiocytes Receptors Signaling

Early changes of graft function,cytokines and superoxide dismutase serum levels after donor liver denervation and Kupffer cell depletion in a rat-to-rat liver transplantation model

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Hepatobiliary & Pancreatic Diseases International 2009年第2期8卷 152-156页

作者： Catena Marco Ferla gianfranco Liver Surgery Unit Scientific Institute Hospital San RaffaeleVita-Salute San Raffaele University School of Medicine

BACKGROUND: Hepatic reperfusion injury may cause acute inflammatory damage, producing significant organ dysfunction, and is an important problem in liver transplantation. This experiment aimed to study early changes of hepatic function after donor liver denervation and Kupffer cell depletion in rat-to-rat liver transplantation and to evaluate the effect of pre-treatment on liver reperfusion injury. METHODS: Donor rats were divided into four groups: control group; group G was pre-treated with gadolinium chloride (G), an inhibitor of Kupffer cells; group H with hexamethonium (H), a sympathetic ganglionic blocking agent; and group HG, with combined H and G pre-treatment. Under the same conditions, serum alanine aminotransferase (ALT), arterial ketone body ratio (AKBR), tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), and superoxide dismutase (SOD) of recipient rats were assessed at 4, 8, 16 and 24 hours after liver transplantation. Histological studies of the grafts were compared. RESULTS: HG pre-treatment significantly decreased ALT, TNF-alpha, and IL-6 levels, increased AKBR and SOD levels, and demonstrated less pathological damage at 8, 16 and 24 hours compared with the control group. Similar trends were also found in the other groups (G and H). However, the differences among them were not significant at 4 postoperative hours. CONCLUSIONS: Donor denervation and Kupffer cell depletion had preventive effect on liver reperfusion injury. HG pre-treatment is a feasible and reproducible method to protect grafts from reperfusion injury.

关键词： liver transplantation reperfusion injury macrophages denervation

Effective Interaction Force between an Electric Charge and a Magnetic Dipole and Locality (or Nonlocality) in Quantum Effects of the Aharonov–Bohm Type

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Chinese Physics Letters 2021年第3期38卷 39-43页

作者： gianfranco Spavieri George T.Gillies Miguel Rodriguez Maribel Perez Centro de Física Fundamental Facultad de CienciasUniversidad de Los AndesMérida 5101Venezuela Department of Mechanical and Aerospace Engineering University of VirginiaCharlottesvilleVA 22904USA Departamento de Física Facultad de Ciencia y TecnologíaUniversidad de CaraboboNaguanagua 2001Venezuela Carrera de Ingeniería Ambiental Facultad de IngenieríaUniversidad Nacional de ChimborazoRiobamba 100150Ecuador

Classical electrodynamics foresees that the effective interaction force between a moving charge and a magnetic dipole is modified by the time-varying total momentum of the interaction fields. We derive the equations of motion of the particles from the total stress-energy tensor, assuming the validity of Maxwell’s equations and the total momentum conservation law. Applications to the effects of Aharonov–Bohm type show that the observed phase shift may be due to the relative lag between interfering particles caused by the effective local force.

关键词： force. momentum interaction

Improving the Hydromechanical Deep-Drawing Process Using Aluminum Tailored Heat Treated Blanks

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Acta Metallurgica Sinica(English Letters) 2015年第12期28卷 1482-1489页

作者： Antonio Piccininni Gabriella Di Michele gianfranco Palumbo Donato Sorgente Luigi Tricarico Dipartimento di Meccanica Matematica e Management Politecnico di Bari

The present work demonstrates the effectiveness of combining the hydromechanical deep-drawing process with the Tailored Heat Treated Blank（THTB） technique. In the hydromechanical deep-drawing process, the fluid pressure is used for postponing the fracture occurrence in the blank, while the THTB technique allows to create a material property gradient through a suitable artificial aging treatment carried out prior to the forming process. Since the number of process variables is large, in the present work the authors propose an optimization loop for the determination of the parameters controlling the extension of the blank regions to be subjected to the aging treatment and the temperature levels to be set during the heat treatment. The proposed methodology couples a simple finite element model（Abaqus） with a multiobjective optimization platform（mode FRONTIER）. A preliminary experimental campaign was carried out for determining the effect of the aging treatment on the mechanical（through tensile tests） and deformative（through formability tests）behavior of the AC170 PX aluminum alloy. Optimization results prove the effectiveness of the adopted methodology and put in evidence that the adoption of properly aged blanks in the hydromechanical deep drawing allows to increase the limit drawing ratio and to simplify the process since it is conducted at room temperature.

关键词： Aluminum alloy Aging Hydromechanical deep drawing Finite element analysis Mechanical characterization Formability

Osmoprotectants and Antioxidative Enzymes as Screening Tools for Salinity Tolerance in Radish (Raphanus sativus)

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Horticultural Plant Journal 2020年第1期6卷 14-24页

作者： Rabab Sanoubar Antonio Cellini Giuseppe gianfranco Francesco Spinelli Department of Agricultural Sciences (DIPSA) University of Bologna

The research addresses the identification of a screening methodology for salt stress tolerance in radish cultivars. In the first experiment, two different radish cultivars(long white and round red) were compared in their morphological and physiological responses to different salinity levels. Round red radish showed better morphological and physiological responses to incremental salinity in terms of yield and better adaptation of overall water relations. In the second experiment, the most tolerant genotype from the first experiment was used as a control against other seven round red radish genotypes ranked by their salinity tolerance according to morphological, physiological and biochemical indices. Salt stress did not significantly affect malondialdehyde(MDA) and hydrogen peroxide(H2O2) content, and ascorbate peroxidase(APX) activity in the studied cultivars. Nonetheless, the relatively salt tolerant cultivar SAXA2 showed higher ability to accumulate compatible solutes(*** and proteins) and maintain osmotic adjustment. In addition, cultivar SAXA2 also showed considerable increase in glutathione reductase(GR) activity. Our results supported that accumulation of proline and higher GR activity are associated with radish salt tolerance, whereas no relationship with salinity was observed in superoxide dismutase(SOD), MDA and H2O2 content.

关键词： radish salt stress oxidative stress secondary metabolite antioxidant enzyme