检索结果-南通市图书馆

“矛盾不上交”的历史语境与时代新义——在法治建设中坚持和发展新时代“枫桥经验”

在线全文

学校读者我要写书评

暂无评论

法治研究 2024年第3期153卷 12-24页

作者：彭巍浙江大学光华法学院

“矛盾不上交”是“枫桥经验”60年发展中始终未变的关键内容。60年代,毛泽东同志基于特定时代背景和现实语境将“枫桥经验”概括为“矛盾不上交,就地解决”。习近平新时代中国特色社会主义思想引领新时代“枫桥经验”创新发展,为“矛... 详细信息

“矛盾不上交”是“枫桥经验”60年发展中始终未变的关键内容。60年代,毛泽东同志基于特定时代背景和现实语境将“枫桥经验”概括为“矛盾不上交,就地解决”。习近平新时代中国特色社会主义思想引领新时代“枫桥经验”创新发展,为“矛盾不上交”赋予了新的时代属性、拓展了适用领域,并将其发展为法治建设的重要部分。历久弥新的“矛盾不上交”表述,是马克思主义基本原理与中国社会主义建设具体实际的结合,是中国传统法治文化与社会主义法治建设实践的融合,是基层群众语言与中央政治话语的统一。在法治中国建设的时代背景下,强调“矛盾不上交”仍然具有广泛的指导作用和应用价值。

关键词：枫桥经验矛盾不上交矛盾法治

Synergistic effects of three traditional herbs green tea,mulberry leaf and corn silk on glucose uptake level of L6 myoblasts and the hypoglycemic mechanism

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Traditional Medicine Research 2024年第7期9卷 1-12页

作者： Jing-Na Zhou Ming-Yue Li Ting-Ting Zhang Jing-Yang Lu Min Zhang peng-wei Zhuang Hai-Xia Chen Tianjin Key Laboratory for Modern Drug Delivery&High-Efficiency School of Pharmaceutical Science and TechnologyTianjin UniversityTianjin 300072China. School of Food Science and Bioengineering Tianjin Agricultural UniversityTianjin 300384China. State Key Laboratory of Nutrition and Safety Tianjin University of Science&TechnologyTianjin 300457China. Haihe Laboratory of Modern Chinese Medicine Chinese Materia Medica CollegeTianjin University of Traditional Chinese MedicineTianjin 301617China.

Background:Green tea,mulberry leaf and corn silk are traditional herbs used in the prevention and treatment of diabetes in China for a long time,but their synergistic hypoglycemic effects and mechanisms remain ***:The effective components of green tea,mulberry leaf and corn silk were extracted and *** design of experiments was used to study the influences of different combinations on the cell viability and glucose uptake level of L6 myoblasts,so as to determine the optimal synergistic hypoglycemic *** possible hypoglycemic mechanism of the optimal synergistic combination was explored by cytotoxicity assay,glucose uptake assay,and western ***:Three polyphenol enrichment fractions of the herbs,30%ethanol elution fraction of green tea(GT),50%ethanol elution fraction of mulberry leaf(ML)and 60%ethanol elution fraction of corn silk(CS)were *** antioxidant activities of GT-30%,ML-50%and CS-60%were superior to those of crude extracts,and showed strong potential inα-amylase andα-glucosidase inhibition *** optimal synergistic combination of crude extracts G7(crude extract of green tea:crude extract of mulberry leaf:crude extract of corn silk=1:5:3),polyphenol enrichment fractions R3(GT-30%:ML-50%:CS-60%=1:7:1)and monomers X2(epigallocatechin gallate:morusin:formononetin=3:1:2)were selected,respectively.G7,R3,and X2 showed promoting effects on the cell viability and glucose uptake of L6 myoblasts within the detected concentration *** addition,G7,R3,and X2 could increase the expression levels of p-PI3K/PI3K and p-Akt/Akt in L6 myoblasts,and promote the translocation of Glut4,but G7 and R3 showed more significant ***:The synergistic hypoglycemic effects of green tea,mulberry leaf and corn silk had the characteristics of multiple-components and multiple-targets with p-PI3K/PI3K,p-Akt/Akt and the translocation of Glut4 signal pathways *** three traditional herbs might have the potential

关键词： green tea mulberry leaf corn silk synergistic effect type 2 diabetes mellitus mechanism

NaYF4:Yb3+,Er3+@SiO2荧光纳米传感器检测牛奶中过氧化氢

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

分析化学 2024年第5期52卷 685-694页

作者：彭孔浩彭微白安琪王凌男赵伟馨武玥郭文李淑荣罗利霞孟佩俊包头医学院公共卫生学院内蒙古自治区卫生检测与评价工程技术中心

采用溶剂热法合成了稀土掺杂上转换纳米材料NaYF4:Yb3+,Er3+，使用反相微乳液法对其表面进行SiO2包覆制得NaYF4:Yb3+,Er3+@Si O2。采用透射电镜、X射线衍射和傅里叶红外光谱对此材料进行了表征，并基于NaYF4:Yb3+,Er3+@SiO2与方酸铁(SQA... 详细信息

采用溶剂热法合成了稀土掺杂上转换纳米材料NaYF4:Yb3+,Er3+，使用反相微乳液法对其表面进行SiO2包覆制得NaYF4:Yb3+,Er3+@Si O2。采用透射电镜、X射线衍射和傅里叶红外光谱对此材料进行了表征，并基于NaYF4:Yb3+,Er3+@SiO2与方酸铁(SQA-Fe3+)之间的荧光猝灭原理构建了NaYF4:Yb3+,Er3+@SiO2-SQA-Fe3+荧光纳米传感器，用于微量过氧化氢（H2O2）的检测。在最佳实验条件下，本方法检测H2O2的线性范围为1.8～84.0μmol/L，检出限（3σ）为0.47μmol/L，牛奶样品中H2O2的加标回收率为98.4%～99.7%。本方法具有检出限低、稳定性好以及抗干扰能力强等优点，可用于牛奶样品中H2O2残留的检测。

关键词：稀土掺杂上转换纳米材料过氧化氢荧光纳米传感器荧光猝灭

来源：博看期刊

Integration of gut microbiota and metabolomics analysis to unravel the neuroprotective effects of Hydroxy-α-sanshool on Alzheimer's Disease

在线全文

学校读者我要写书评

暂无评论

Food Science and Human Wellness 2024年

作者： Ruo-Lan Li Wen-Wen Chen Hong Zhang Qi Liang Ling-Yu Wang wei peng Chun-Jie Wu State Key Laboratory of Southwestern Chinese Medicine Resources School of Pharmacy Chengdu University of Traditional Chinese Medicine Institute of Innovation Chengdu University of Traditional Chinese Medicine Sichuan Cancer Hospital and Institute School of Medicine University of Electronic Science and Technology of China Chengdu Women's and Children's Central Hospital School of Medicine University of Electronic Science and Technology of China Meishan Hospital of TCM Meishan Hospital Affiliated to Chengdu University of Traditional Chinese Medicine

Alzheimer's disease （AD） is a common neurodegenerative disease， and oxidative stress induced by Aβ deposition is the key cause of neuronal apoptosis in AD patient. Hydroxy-α-sanshool （HAS） is the predominant flavour substances in the pericarp of Zanthoxylum bungeanum Maxim. （Rutaceae family）， which is a known condiment food and herbal medicine in China. We attempt to comprehensively elucidate the pathway and related mechanisms of HAS therapy on AD through in vivo and in vitro experiments. The results showed that HAS could inhibit cell apoptosis， suppress the reactive oxygen species （ROS）， and increase the antioxidative enzymes in Aβ1-42induced HT22 cells. In vivo， HAS attenuated the learning and memory impairment in senescence-accelerated mouse prone 8 （SAMP8） mice， and protected neuronal cells in hippocampus. Interestingly， the 16S rRNA gene sequencing results showed HAS could restore the richness and diversity of the intestinal microbiota， reduce the abundance of Lactobacillus， and increase the abundance of Bateroides and Parabacteroides. Moreover， the contents of 10 metabolites were significantly changed after HAS treatment， which was beneficial to treat AD. In conclusion， HAS could inhibit apoptosis in nerve cells by attenuating Aβ induced oxidative stress level， while it can also influence the metabolic pathways and affect the gut microbiota composition of AD mice.

关键词：

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

农用拖拉机造型设计与应用研究

农机化研究 2024年第12期46卷 264-268页

作者：魏鹏唐山学院河北唐山063000

鉴于用户对于拖进机外观造型要求提高的现状,对农用拖拉机造型设计与应用进行了研究。拖拉机的整体造型采用逆向工程的方法进行设计,系统分为监控层、应用层、造型设计层和数据库。在进行农用拖拉机造型设计时,除了满足功能和美观的需... 详细信息

鉴于用户对于拖进机外观造型要求提高的现状,对农用拖拉机造型设计与应用进行了研究。拖拉机的整体造型采用逆向工程的方法进行设计,系统分为监控层、应用层、造型设计层和数据库。在进行农用拖拉机造型设计时,除了满足功能和美观的需要之外,还应使结构具有足够的强度和刚度。为此,通过对拖拉机主要受力部分驾驶室和车架的结构进行有限元分析,保证各部分强度低于材料的许用应力。为了验证农用拖拉机造型的合理性,对其进行强度校核试验和用户美观评价试验,结果表明:拖拉机的强度和刚度可保证结构的安全,且造型基本符合用户的审美要求。

关键词：农用拖拉机造型设计有限元分析逆向工程虚拟样机

健康教育联合穴位艾灸护理对急性盆腔炎患者临床症状及复发情况的影响

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

医学信息 2024年第12期37卷 148-151页

作者：彭维萍萍乡市中医院妇产科

目的研究健康教育联合穴位艾灸护理对急性盆腔炎患者临床症状及复发情况的影响。方法选取2019年1月-2021年12月在我院诊治的78例慢性盆腔炎患者为研究对象，采用随机数字表法分为对照组和观察组，各39例。对照组采用常规护理，观察组... 详细信息

目的研究健康教育联合穴位艾灸护理对急性盆腔炎患者临床症状及复发情况的影响。方法选取2019年1月-2021年12月在我院诊治的78例慢性盆腔炎患者为研究对象，采用随机数字表法分为对照组和观察组，各39例。对照组采用常规护理，观察组在对照组基础上采用健康教育联合穴位艾灸护理，比较两组患者临床症状改善时间、疾病健康知识水平、护理满意度、生活质量水平、复发率。结果观察组临床腹部疼痛、阴道分泌物减少、腹部坠胀、腰骶酸痛改善时间均小于对照组（P<0.05）；观察组患者疾病认知、禁忌事项、治疗知识、护理知识评分均高于对照组（P<0.05）；观察组护理满意度为94.87%，高于对照组的82.05%(P<0.05)；两组干预后生活质量评分高于干预前，且观察组高于对照组（P<0.05）；随访6个月，观察组复发率为7.69%，低于对照组的17.95%(P<0.05)。结论健康教育联合穴位艾灸护理可加速急性盆腔炎患者临床症状改善，提高患者疾病健康知识水平，提高患者护理满意度，提升患者生活质量水平，降低复发率，实现较为理想的护理效果。

关键词：健康教育穴位艾灸慢性盆腔炎复发率

Ilizarov technique for treating elbow stiffness caused by myositis ossificans:A case report

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2024年第17期12卷 3144-3150页

作者： Ming-Wang Zhou peng-wei Zhang An-Le Zhang Chang-Hao wei Yu-De Xu wei Chen Zhi-Bin Fu Department of Orthopedics Medicine Gansu Province Hospital of Chinese MedicineLanzhou 730050Gansu ProvinceChina Gansu University of Chinese Medicine Clinical College of Traditional Chinese MedicineLanzhou 730000Gansu ProvinceChina

BACKGROUND Myositis ossificans(MO)is a rare disease involving the formation of bone outside the musculoskeletal *** surgical intervention is the main treatment approach,preventing recurrence and standardized rehabilitation are also ***,we present a surgical strategy to prevent the recurrence of *** SUMMARY A 28-year-old female patient was admitted for the first time for a comminuted fracture of the left ***,incorrect postoperative rehabilitation resulted in the development of elbow joint stiffness with ectopic ossification,causing a loss of normal range of *** patient was diagnosed with MO based on physical examination,X-ray findings,and clinical *** devised a surgical strategy to remove MO,followed by fixation with an Ilizarov frame,and implemented a scientifically reasonable rehabilitation *** surgery lasted for 3 h with an estimated blood loss of 45 mL.A drainage tube was placed after surgery,and fluid was aspirated through ultrasound-guided *** patient experienced a significant reduction in joint stiffness after *** the final follow-up at 9 mouths,there was evident improvement in the range of motion of the elbow joint,and no other symptoms were *** The Ilizarov frame is an advantageous surgical technique for facilitating rehabilitation after MO *** offers benefits such as passive recovery,individualized treatment,and prompt recovery.

关键词： Myositis ossificans Ilizarov frame Rehabilitation strategy Stiffness Case report

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

基于Rényi-α熵的参数化纠缠度量

物理学报 2024年第4期73卷 37-46页

作者：戴伟鹏贺衎侯晋川太原理工大学数学学院太原030024

与各种非参数化纠缠度量相比,参数化纠缠度量显示了其优越性.并发纠缠被广泛用于描述量子实验中的纠缠.作为一种纠缠度量,它与特定Rényi-α熵有关.本文提出了一种基于Rényi-α熵的参数化两体纠缠度量,命名为α-对数并发纠缠.与现有的... 详细信息

与各种非参数化纠缠度量相比,参数化纠缠度量显示了其优越性.并发纠缠被广泛用于描述量子实验中的纠缠.作为一种纠缠度量,它与特定Rényi-α熵有关.本文提出了一种基于Rényi-α熵的参数化两体纠缠度量,命名为α-对数并发纠缠.与现有的参数化度量不同,首先定义了纯态的度量,然后推广到混合态.进一步验证了α-对数并发纠缠满足纠缠度量3个条件.展示了对纯态的度量是容易计算的,然而对于混合态,解析计算只适用于特殊的双量子位态或特殊的高维混合态.因此,本文致力于建立一般两体态α-对数并发纠缠的一个下界.令人惊讶的是,这个下界是这个混合态的正部分转置判据和重排判据的函数.这表明了3种纠缠度量之间的联系.有趣的是,下界依赖于与具体态相关的熵参数.这样我们可以选择适当的参数α,使得Gα(ρ)≫0用于特定态ρ的实验纠缠检测.此外,计算了isotropic态的α-对数并发纠缠的表达式,并给出了d=2时isotropic态的解析表达式.最后,讨论了α-对数并发纠缠的的单配性.建立了两个量子比特系统中并发纠缠和α-对数并发纠缠之间的函数关系,然后得到了该函数的一些有用性质,并结合Coffman-Kundu-Wootters(CKW)不等式,建立了关于α-对数并发纠缠的单配性不等式.最终证明了单配性不等式对于α-对数并发纠缠是成立的.

关键词：参数化度量 Rényi-α熵纠缠度量并发纠缠

Humanβ-defensin-1 affects the mammalian target of rapamycin pathway and autophagy in colon cancer cells through long noncoding RNA TCONS_00014506

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2024年第4期16卷 1465-1478页

作者： Yu-Xin Zhao Yan Cui Xin-Hong Li Wen-Hong Yang Shi-Xiang An Jia-Xian Cui Min-Yu Zhang Jing-Kun Lu Xuan Zhang Xiu-Mei Wang Li-Li Bao peng-wei Zhao Department of Anesthesiology Inner Mongolia Chest HospitalThe Fourth HospitalHohhot 010035Inner Mongolia Autonomous RegionChina College of Humanities and Education Inner Mongolia Medical UniversityHohhot 010059Inner Mongolia Autonomous RegionChina Department of Radiotherapy The Affiliated Hospital of Inner Mongolia Medical UniversityHohhot 010059Inner Mongolia Autonomous RegionChina School of Basic Medical Science Inner Mongolia Medical UniversityHohhot 010059Inner Mongolia Autonomous RegionChina Department of Medical Oncology The Affiliated Cancer Hospital of Inner Mongolia Medical UniversityHohhot 010050Inner Mongolia Autonomous RegionChina

BACKGROUND Colorectal cancer has a low 5-year survival rate and high ***β-defensin-1(hBD-1)may play an integral function in the innate immune system,contributing to the recognition and destruction of cancer *** non-coding RNAs(lncRNAs)are involved in the process of cell differentiation and *** To investigate the effect of hBD-1 on the mammalian target of rapamycin(mTOR)pathway and autophagy in human colon cancer SW620 *** CCK8 assay was utilized for the detection of cell proliferation and determination of the optimal drug *** formation assay was employed to assess the effect of hBD-1 on SW620 cell *** was used to screen potentially biologically significant lncRNAs related to the mTOR ***,p-mTOR(Ser2448),Beclin1,and LC3II/I expression levels in SW620 cells were assessed through Western blot *** hBD-1 inhibited the proliferative ability of SW620 cells,as evidenced by the reduction in the colony formation capacity of SW620 cells upon exposure to ***-1 decreased the expression of p-mTOR(Ser2448)protein and increased the expression of Beclin1 and LC3II/I ***,bioinformatics analysis identified seven lncRNAs(2 upregulated and 5 downregulated)related to the mTOR *** lncRNA TCONS_00014506 was ultimately *** the inhibition of the lncRNA TCONS_00014506,exposure to hBD-1 inhibited p-mTOR(Ser2448)and promoted Beclin1 and LC3II/I protein *** hBD-1 inhibits the mTOR pathway and promotes autophagy by upregulating the expression of the lncRNA TCONS_00014506 in SW620 cells.

关键词： Colon cancer Humanβ-defensin-1 LncRNA Mammalian target of rapamycin Autophagy