检索结果-南通市图书馆

A Novel Model Calibration Method for Active Magnetic Bearing Based on Deep Reinforcement Learning

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Guidance, Navigation and Control 2023年第3期3卷 110-128页

作者： Bingyun Yang cong peng Fei Jiang Sumu Shi College of Automation Engineering Nanjing University of Aeronautics and Astronautics Nanjing 211106P.R.China

Active magnetically suspended control moment gyro is a novel attitude control actuator for *** is mainly composed of rotor,active magnetic bearing(AMB)and *** a crucial supporting component of control moment gyro,the performance of AMB is directly related to the stability of the rotor system and pointing precision of the ***,calibrating the parameters of AMB is essential for the realization of super-quiet *** paper proposed a model calibration method,known as the deep reinforcement learningbased model calibration frame(DRLMC).First,the dynamics of magnetic bearing with damage degradation over its life cycle are ***,the calibration process is formulated as a Markov Decision Process(MDP),and reinforcement learning(RL)is employed to infer the degradation *** addition,experience replay and target network update mechanism are introduced to guarantee *** results demonstrate that the proposed method identi¯es force-current factor of AMB during its degradation process e®***,additional experiments con¯rm the robustness of the DRLMC approach.

关键词： Control moment gyro active magnetic bearing model calibration reinforcement learning

A certificateless Multi-receiver Encryption scheme based on SM2 signature algorithm

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

高置信计算(英文) 2023年第1期3卷 66-74页

作者： Jinglin Zou Debiao He Sheng Bi Libing Wu Zhe Liu cong peng School of Cyber Science and Engineering Wuhan UniversityWuhan 430072China Changjiang River Scientific Research Institute Wuhan 250031China School of Cyber Science and Engineering Nanjing University of Aeronautics and AstronauticsNanjing 210016China

The Multi-receiver Encryption(MRE)scheme can meet the secure data transmission requirements in multicast and broadcast *** meet compliance,critical information infrastructure in China should be protected with Chinese national commercial cryptographic *** an MRE scheme based on Elliptic Curve Cryptography(ECC)is one of the current design methods with better flexibility and ***,the research on MRE schemes based on SM2 elliptic curve public-key cryptography is still in a blank *** paper proposes a Certificateless SM2-based Multireceiver Encryption(CL-SM2-MRE)*** prove the security of the CL-SM2-MRE scheme under the Random Oracle Model(ROM)and analyze the performance.

关键词： SM2 Certificateless multireceiver encryption Provable security

Smooth tracking control for conversion mode of a tilt-rotor aircraft with switching modeling

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Information Technology & Electronic Engineering 2023年第11期24卷 1591-1600页

作者： Kebi LUO Shuang SHI cong peng College of Automation Engineering Nanjing University of Aeronautics and AstronauticsNanjing 211106China

This paper investigates the state-tracking control problem in conversion mode of a tilt-rotor aircraft with a switching modeling method and a smooth interpolation *** on the nonlinear model of the conversion mode,a switched linear model is developed by using the Jacobian linearization method and designing the switching signal based on the mast ***,an ℋ_(∞) state-tracking control scheme is designed to deal with the conversion mode control ***,instead of limiting the amplitude of control inputs,a smooth interpolation method is developed to create bumpless ***,the XV-15 tilt-rotor aircraft is chosen as a prototype to illustrate the effectiveness of this developed control method.

关键词： Tilt-rotor aircraft State-tracking control Switched linear systems Time-scheduled multiple Lyapunov function approach Smooth interpolation

在线全文

学校读者我要写书评

暂无评论

技术标准实施效益评价方法研究

中国标准化 2024年第19期 82-90页

作者：张家琪马莉赵臻霞丛鹏伟国家电网有限公司国网能源研究院有限公司北京国网信通埃森哲信息技术有限公司

标准化水平是衡量企业核心竞争力的重要指标,客观、科学的标准实施效益评价对进一步做好标准化工作具有重大战略意义。本文针对大型公益企业标准实施效益量化难、单项标准贡献度分离难的问题,分析了技术标准产生效益的作用机理,提出了... 详细信息

标准化水平是衡量企业核心竞争力的重要指标,客观、科学的标准实施效益评价对进一步做好标准化工作具有重大战略意义。本文针对大型公益企业标准实施效益量化难、单项标准贡献度分离难的问题,分析了技术标准产生效益的作用机理,提出了业务链条准确关联技术标准与实施效益、量化评估标准对业务的贡献度的“全链条价值分解法”,探讨了该方法的总体思路和评价框架,最后通过具体案例实现技术标准体系化实施效益评价和分析。实践结果表明该方法适用于大型公益性企业的技术标准体系化实施效益评价,填补了大型公益性企业在系统性评估标准实施效益方法上的空白。

关键词：标准化实施效益评价方法技术标准体系化

维普期刊数据库博看期刊

Eubacterium rectale Improves the Efficacy of Anti-PD1 Immunotherapy in Melanoma via l-Serine-Mediated NK Cell Activation

在线全文

学校读者我要写书评

暂无评论

Research 2023年第4期2023卷 777-792页

作者： Nian Liu Lihui Chen Mingjie Yan Qian Tao Jie Wu Jing Chen Xiang Chen Wei Zhang cong peng Department of Clinical Pharmacology Xiangya HospitalCentral South UniversityChangshaHunanChina Department of Dermatology Xiangya HospitalCentral South UniversityChangshaHunanChina Hunan Key Laboratory of Skin Cancer and Psoriasis Xiangya HospitalCentral South UniversityChangshaHunanChina Furong Laboratory Xiangya HospitalCentral South UniversityChangshaHunanChina National Clinical Research Center for Geriatric Disorders Xiangya HospitalCentral South UniversityChangshaHunanChina

Natural killer(NK)cells,as key immune cells,play essential roles in tumor cell immune escape and *** evidence has demonstrated that the gut microbiota community affects the efficacy of anti-PD1 immunotherapy and that remodeling the gut microbiota is a promising strategy to enhance anti-PD1 immunotherapy responsiveness in advanced melanoma patients;however,the details of the mechanism remain *** this study,we found that Eubacterium rectale was significantly enriched in melanoma patients who responded to anti-PD1 immunotherapy and that a high *** abundance was related to longer survival in melanoma ***,administration of *** remarkably improved the efficacy of anti-PD1 therapy and increased the overall survival of tumor-bearing mice;moreover,application of *** led to a significant accumulation of NK cells in the tumor ***,conditioned medium isolated from an *** culture system dramatically enhanced NK cell *** chromatography-mass spectrometry/ultrahigh performance liquid chromatography-tandem mass spectrometry-based metabolomic analysis showed that l-serine production was significantly decreased in the *** group;moreover,administration of an l-serine synthesis inhibitor dramatically increased NK cell activation,which enhanced anti-PD1 immunotherapy ***,supplementation with l-serine or application of an l-serine synthesis inhibitor affected NK cell activation through Fos/*** summary,our findings reveal the role of bacteria-modulated serine metabolic signaling in NK cell activation and provide a novel therapeutic strategy to improve the efficacy of anti-PD1 immunotherapy in melanoma.

关键词： PD1 rectal melanoma

circ-CPA4调节miR-140-3p/SGK1轴对非小细胞肺癌细胞增殖、凋亡、迁移和侵袭的影响

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

现代生物医学进展 2024年第13期24卷 2455-2462页

作者：龚程高明悦孟俊宏彭聪徐健刘杜先南京中医药大学附属南京医院(南京市第二医院)病理科江苏南京210000 南京中医药大学附属南京医院(南京市第二医院)心胸外科江苏南京210000

目的:探讨环状RNA羧肽酶A4(circ-CPA4)调节miR-140-3p/血清和糖皮质激素诱导的蛋白激酶-1(SGK1)轴对非小细胞肺癌(NSCLC)细胞增殖、凋亡、迁移和侵袭的影响。方法:将H1299细胞分为5组:Ct组、si-NC组、si-circ-CPA4组、si-circ-CPA4+inhibitor-NC组、si-circ-CPA4+miR-140-3p inhibitor组。采用实时荧光定量逆转录聚合酶链反应(qRT-PCR)检测circ-CPA4、miR-140-3p表达;流式细胞术检测细胞凋亡;细胞计数试剂盒(CCK-8)法检测细胞增殖;划痕愈合实验检测细胞迁移;Transwell检测细胞侵袭;免疫印迹检测SGK1、半胱氨酸蛋白酶3(Caspase-3)、细胞周期蛋白D1(CyclinD1)、基质金属蛋白酶2(MMP-2)蛋白表达;双荧光素酶报告基因实验检测circ-CPA4与miR-140-3p、miR-140-3p与SGK1的靶向关系。将上述5组细胞悬液分别皮下注射到裸鼠体内,30天后,处死裸鼠并分离肿瘤,称量肿瘤质量。结果:在NSCLC组织和细胞中circ-CPA4、SGK1蛋白高表达,miR-140-3p低表达。si-circ-CPA4组与Ct组、si-NC组比较,circ-CPA4、划痕愈合率、OD_(450)值、侵袭细胞数、SGK1、CyclinD1、MMP-2蛋白表达及裸鼠体内肿瘤质量显著降低,miR-140-3p表达、细胞凋亡率、Caspase-3蛋白表达水平显著升高(P<0.05);与si-circ-CPA4+inhibitor-NC组比较,si-circ-CPA4+miR-140-3p inhibitor组对应指标变化趋势与上述相反(P<0.05);沉默circ-CPA4可靶向下调miR-140-3p表达,下调miR-140-3p可靶向促进SGK1蛋白表达。结论:沉默circ-CPA4通过上调miR-140-3p来抑制SGK1蛋白表达,从而抑制NSCLC细胞增殖、迁移、侵袭,并促进细胞凋亡。

关键词： circ-CPA4 miR-140-3p SGK1 非小细胞肺癌细胞增殖细胞凋亡迁移侵袭

Yellow nail syndrome accompanied by minimal-change nephrotic syndrome:A case report

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2022年第15期10卷 4949-4956页

作者： Ya-Nan Zhang Mei-Hua Wang Wen-Cheng Yu Wei Cheng Jin-peng cong Xue-peng Huang Fang-Fang Wang Department of Respiratory and Critical Care Medicine The Affiliated Hospital of Qingdao UniversityQingdao 266000Shandong ProvinceChina Department of Respiratory and Critical Care Medicine People's Hospital of Rizhao LanshanRizhao 276800Shandong ProvinceChina

BACKGROUND In most cases of yellow nail syndrome(YNS),the classic triad of yellow nails,lymphedema and respiratory manifestations rarely manifest ***,diagnosis is delayed or frequently *** SUMMARY We report a 62-year-old YNS patient presenting with bilateral pleural,pericardial and peritoneal effusions who,2 mo later,developed minimal-change nephrotic *** treatment with vitamin E,clarithromycin and prednisone for 3 mo,effusions in the chest,pericardium and abdominal cavity decreased while urine protein levels returned to within normal *** Clinicians should consider the possibility of YNS for patients presenting with multiple serous effusions and nephrotic syndromes.

关键词： Yellow nail syndrome Pleural effusion Pericardial effusion Peritoneal effusion Nephrotic syndrome Case report

^(60)Co集装箱CT系统图像重建的MPI并行实现

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

核电子学与探测技术 2006年第1期26卷 30-32,40页

作者：丛鹏清华大学核能与新能源技术研究院北京100084

利用M P I并行编程环境,对原有重建CT图像顺序流程并行化,实现了并行计算流程。在4个计算节点的情况下,使重建图像耗时由34s缩短到9s,基本实现了线性加速,获得了很好的重建速度。

关键词：并行计算MPI CT图像重建

面向资源重用的航空发动机试车台架多目标优化设计

在线全文

学校读者我要写书评

暂无评论

制造业自动化 2024年第4期46卷 142-148,189页

作者：黄利江姚雄范泽兵彭永骢田锡天西北工业大学西安710072 中国航发四川燃气涡轮研究院江油621703

针对航空发动机试车台架设计周期长、效率低的问题,从成本控制和资源重用出发,提出面向资源重用的试车台架多目标优化设计方法。在分析航空发动机试车台架特点及快速配置需求的基础上,构建了以生产成本、生产时间和产品寿命均衡性为目... 详细信息

针对航空发动机试车台架设计周期长、效率低的问题,从成本控制和资源重用出发,提出面向资源重用的试车台架多目标优化设计方法。在分析航空发动机试车台架特点及快速配置需求的基础上,构建了以生产成本、生产时间和产品寿命均衡性为目标的试车台架配置多目标优化模型。通过混合深度优先搜索算法(DFS)的改进遗传算法(INSGA-Ⅱ)求解了试车台架设计模块的可配置解集,并采用TOPSIS法求解得了最优可配置设计方案。通过算法效果比较,以及某航空发动机高空模拟试车台架快速设计实例分析,说明了所提方法的可行性和有效性。

关键词：发动机试车台架资源重用模块配置多目标优化