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0CT测量肾脏长度用于预测活体肾供者的单侧肾GFR

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国际医学放射学杂志 2017年第2期 240-240页

作者： F.Gaillard P.pavlov A.M.Tissier B.Harache D.Eladari M.O.Timsit 石冰 AP-HP Hpital Necker-Enfants MaladesRenal Trans-plantation DepartmentParis Descartes University

摘要目的活体肾供者的筛选需要闪烁扫描测定单侧肾的肾小球滤过率(GFR)。为了明确CT对于评估单侧肾GFR的作用,将闪烁扫描与CT测定单侧GFR进行比较,评

关键词：单侧肾闪烁扫描放射性同位素扫描 GFR 活体肾脏尺寸长度供者 CT

基于中维西理论的支气管哮喘患者中枢神经系统研究(英文)

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新疆医科大学学报 2013年第3期 296-306页

作者： Igor Gogol 哈木拉提·吾甫尔努尔买买提·艾买提 Denis Dubrovin 巴甫洛夫的医科大学临床医学部新疆医科大学维吾尔医学院

将112例持续状态的中度哮喘、重度哮喘进行临床类型分类,然后根据维吾尔医体液对分型和诊断分为异常胆液质型、异常黑胆质型和异常粘液质型。同时根据中医辨证分型将患者分为肾阳虚、肾阴虚、痰瘀和肝气郁结型。采用脑电图(electroencep... 详细信息

将112例持续状态的中度哮喘、重度哮喘进行临床类型分类,然后根据维吾尔医体液对分型和诊断分为异常胆液质型、异常黑胆质型和异常粘液质型。同时根据中医辨证分型将患者分为肾阳虚、肾阴虚、痰瘀和肝气郁结型。采用脑电图(electroencephalogram,EEG)检测相应证型的EEG特征。发现现代医学的非激素依赖性哮喘和感染性哮喘,维吾尔医异常黑胆质型哮喘和中医痰瘀哮喘3-stem EEG特别明显。说明患者存在中枢神经系统功能紊乱。重度哮喘患者3rd EEG variant非常常见。过敏性哮喘、异常胆液质型哮喘、肝气郁结型和肾阴虚型以1-normal and 2-diencephalic最为常见。说明不同的医学体系在EEG方面存在共性。

关键词：支气管哮喘中枢神经系统脑电图结合研究

维药异常黑胆质成熟剂对异常黑胆质型支气管哮喘模型大鼠尿液代谢物的影响

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新疆医科大学学报 2013年第4期 419-426页

作者：娜祖科·库尔班塔依巴吐尔·买买提明买吾拉尼江·依孜布拉 Denise Dubrovin 哈木拉提·吾甫尔新疆医科大学基础医学院新疆医科大学药学院圣彼得堡巴甫洛夫国立医科大学俄罗斯传统医学院新疆医科大学维吾尔医学院

目的探讨维药异常黑胆质成熟剂对异常黑胆质型支气管哮喘大鼠尿液代谢物变化的影响。方法应用多因素复合作用建立异常黑胆质证载体动物模型,采用卵清蛋白(OVA)致敏和雾化激发方法建立异常黑胆质型支气管哮喘病证模型,将SD大鼠(84只)随... 详细信息

目的探讨维药异常黑胆质成熟剂对异常黑胆质型支气管哮喘大鼠尿液代谢物变化的影响。方法应用多因素复合作用建立异常黑胆质证载体动物模型,采用卵清蛋白(OVA)致敏和雾化激发方法建立异常黑胆质型支气管哮喘病证模型,将SD大鼠(84只)随机分为空白对照组、异常黑胆质证载体模型组、异常黑胆质证型支气管哮喘模型组、异常黑胆质成熟剂给药组(分为大、中、小剂量组)、地塞米松给药阳性对照组。收集各组大鼠尿液,利用核磁共振波谱(1 H-NMR)技术测定核磁共振氢谱,建立大鼠尿液的代谢指纹谱,运用正交偏最小二乘判别分析(OPLS-DA)法分析各组大鼠尿液中代谢产物差异。结果与空白对照组相比,异常黑胆质型哮喘模型组柠檬酸、肌酸酐、甘氨酸等重要氨基酸含量降低,差异有统计学意义(P<0.05);灌胃异常黑胆质成熟剂之后,异常黑胆质型哮喘模型组降低的肌酸酐及乙酸等含量明显增高,牛磺酸、甜菜碱等含量降低,与异常黑胆质型哮喘模型组比较差异有统计学意义(P<0.05);与异常黑胆质型哮喘模型组相比,地塞米松给药阳性对照组马尿酸、乳酸、丙氨酸等含量升高(P<0.05)。结论异常黑胆质成熟剂对异常黑胆质型哮喘大鼠代谢具有显著影响,其作用机制可能是通过作用于异常黑胆质型支气管哮喘大鼠体内氨基酸代谢与能量代谢途径而发挥预防及治疗异常黑胆质型支气管哮喘的作用。

关键词：异常黑胆质证哮喘代谢组学核磁共振大鼠尿液

基于NMR代谢组学方法研究异常黑胆质成熟剂对异常黑胆质型2型糖尿病大鼠的作用机制

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新疆医科大学学报 2013年第4期 411-418页

作者：买吾拉尼江·依孜布拉巴吐尔·买买提明娜祖科·库尔班塔依 Denis Dubrovin 哈木拉提·吾甫尔新疆医科大学基础医学院新疆医科大学药学院圣彼得堡巴甫洛夫国立医科大学俄罗斯传统医学院新疆医科大学维吾尔医学院

目的探讨异常黑胆质成熟剂(ASM)对异常黑胆质型2型糖尿病(T2DM)大鼠的作用机制。方法采用核磁共振(NMR)技术结合模式识别和正交偏最小二乘判别(OPLS-DA)分析方法,寻找灌胃不同剂量ASM混悬液后异常黑胆质型T2DM大鼠尿液中的差异性代谢产... 详细信息

目的探讨异常黑胆质成熟剂(ASM)对异常黑胆质型2型糖尿病(T2DM)大鼠的作用机制。方法采用核磁共振(NMR)技术结合模式识别和正交偏最小二乘判别(OPLS-DA)分析方法,寻找灌胃不同剂量ASM混悬液后异常黑胆质型T2DM大鼠尿液中的差异性代谢产物以及发生改变的代谢网络,分析ASM对异常黑胆质型T2DM大鼠尿液代谢的影响。结果灌胃ASM后,在异常黑胆质型T2DM大鼠尿液中下降的亮氨酸、苯丙氨酸、异亮氨酸以及柠檬酸、α-酮戊二酸、马尿酸、甲酸显著增加,同时在异常黑胆质型T2DM大鼠尿液中增多的β-葡萄糖和α-葡萄糖含量明显降低,与异常黑胆质型T2DM模型组比较差异有统计学意义(P<0.05)。结论 ASM对异常黑胆质型T2DM大鼠尿液代谢有显著影响,其作用机制可能是通过作用于异常黑胆质型T2DM引起的大鼠体内发生紊乱的糖代谢及氨基酸代谢而发挥治疗和预防异常黑胆质型T2DM的作用。

关键词：异常黑胆质成熟剂代谢组学核磁共振 2型糖尿病

Research and development of the back-end electronics for the two-dimensional improved resistive plate chambers in CMS upgrade

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Radiation Detection Technology and Methods 2021年第2期5卷 181-191页

作者： P.Cao Z-A.Liu J.Zhao H.Kou J.Tao J.Song W.Gong N.Wang A.Samalan M.Tytgat N.Zaganidis G.A.Alves F.Marujo F.Torres.Da.S.ilva.De.Araujo E.M.Da Costa D.De Jesus Damiao H.Nogima A.Santoro S.Fonseca De Souza A.Aleksandrov R.Hadjiiska P.Iaydjiev M.Rodozov M.Shopova G.Sultanov M.Bonchev A.Dimitrov L.Litov B.pavlov P.Petkov A.Petrov S.J.Qian C.Bernal A.Cabrera J.Fraga A.Sarkar S.Elsayed Y.Assran M.El Sawy M.A.Mahmoud Y.Mohammed X.Chen C.Combaret M.Gouzevitch G.Grenier I.Laktineh L.Mirabito K.Shchablo I.Bagaturia D.Lomidze I.Lomidze V.Bhatnagar R.Gupta P.Kumari J.Singh V.Amoozegar B.Boghrati M.Ebraimi R.Ghasemi M.Mohammadi Najafabadi E.Zareian M.Abbrescia R.Aly W.Elmetenawee N.De Filippis A.Gelmi G.Iaselli S.Leszki F.Loddo I.Margjeka G.Pugliese D.Ramos L.Benussi S.Bianco D.Piccolo S.Buontempo A.Di Crescenzo F.Fienga G.De Lellis L.Lista S.Meola P.Paolucci A.Braghieri P.Salvini P.Montagna C.Riccardi P.Vitulo B.Francois T.J.Kim J.Park S.Y.Choi B.Hong K.S.Lee J.Goh H.Lee J.Eysermans C.Uribe Estrada I.Pedraza H.Castilla-Valdez A.Sanchez-Hernandez C.A.Mondragon Herrera D.A.Perez Navarro G.A.Ayala Sanchez S.Carrillo E.Vazquez A.Radi A.Ahmad I.Asghar H.Hoorani S.Muhammad M.A.Shah I.Crotty Department of Physics and Astronomy Ghent UniversityProeftuinstraat 869000 GhentBelgium Centro Brasileiro Pesquisas Fisicas R.Dr.Xavier Sigaud150-UrcaRio de JaneiroRJ 22290-180Brazil Dep.de Fisica Nuclear e Altas Energias Instituto de FisicaUniversidade do Estado do Rio de JaneiroRua Sao Francisco Xavier524BR-Rio de Janeiro 20559-900RJBrazil Bulgarian Academy of Sciences Inst.for Nucl.Res.and Nucl.EnergyTzarigradsko shaussee Boulevard 721784 SofiaBulgaria Faculty of Physics University of Sofia5 James Bourchier Boulevard1164 SofiaBulgaria School of Physics Peking UniversityBeijing 100871China Institute of High Energy Physics UCAS/CAS19(B)Yuquan RoadShijingshan DistrictBeijing 100049China Universidad de Los Andes Apartado Aereo 4976Carrera 1Eno.18A 10BogotaCOColombia Egyptian Network for High Energy Physics Academy of Scientific Research and Technology101 Kasr El-Einy St.CairoEgypt The British University in Egypt(BUE) P.O.Box 43Elsherouk CitySuez Desert RoadCairo 11837Egypt Suez University Elsalam CitySuez-Cairo RoadSuez 43522Egypt Department of Physics Faculty of ScienceBeni-Suef UniversityBeni-SuefEgypt Center for High Energy Physics Faculty of ScienceFayoum UniversityEl-Fayoum 63514Egypt Univ Lyon Univ Claude Bernard Lyon 1CNRS/IN2P3IP2I LyonUMR 582269622 VilleurbanneFrance Georgian Technical University 77 Kostava Str.Tbilisi 0175Georgia Department of Physics Panjab UniversityChandigarh 160014India School of Particles and Accelerators Institute for Research in Fundamental Sciences(IPM)P.O.Box 19395-5531TehranIran School of Engineering Damghan UniversityDamghan ***Iran INFN Sezione di BariVia Orabona 470126 BariItaly INFN Laboratori Nazionali di Frascati(LNF)Via Enrico Fermi 4000044 FrascatiItaly INFN Sezione di NapoliComplesso Univ.Monte S.AngeloVia Cintia80126 NaplesItaly INFN Sezione di PaviaVia Bassi 6PaviaItaly INFN Sezione di Pavia and University of PaviaVia Bassi 6PaviaItaly Hanyang University 222 Wangsimni-roSageun-dongSeongdong

Purpose To complement and ensure redundancy in the endcap muon system of the Compact Muon Solenoid(CMS)detector and to extend the Resistive Plate Chamber(RPC)system coverage,improved RPCs(iRPCs)with either orthogonal layer strips with one-end electronics or single layer strips with two-end electronics providing more precise time measurement will be installed in the very forward pseudorapidity region of|η|<*** iRPC readout system needs to support twodimensional(2D)or two-end *** addition,it must combine detector data with Timing,Trigger and fast Control(TTC)and Slow Control(SC)into one data stream over a bi-directional optical link with a line rate of 4.8 Gb/s between the Front-End Electronics(FEE)and the Back-End Electronics(BEE).To fulfill these requirements,a prototype BEE for the iRPC 2D chamber has been researched and *** A Micro-Telecommunication and Computing Architecture(μTCA)-based processing card was designed in this study to establish a prototype system together with aμTCA *** Giga-Bit Transceiver(GBT)protocol is integrated to provide bi-directional communication between the FEE and BEE.A server is connected with the BEE by a Gigabit Ethernet(GbE)link for SC and a 10-GbE link for Data AcQuisition(DAQ).Results The Bit Error Rate(BER)test of the back-end board and a joint test with the iRPC 2D prototype chamber were *** less than 1.331×10−16 was *** timemeasurement with a resolution of 3.05 nswas successfully realized,and detector efficiencies of 97.7%for longitudinal strips and 96.0%for orthogonal strips were *** results demonstrate the correctness and reliability of the prototype *** The BEE prototype satisfies the requirements for the iRPC 2D chamber,and it worked stably and reliably during a long-term joint test run.

关键词： CMS iRPC TTC SC BEE μTCA GBT DAQ

R&D of back-end electronics for improved resistive plate chambers for the phase 2 upgrade of the CMS end-capmuon system

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Radiation Detection Technology and Methods 2022年第3期6卷 306-316页

作者： H.Kou Z.-A.Liu J.Zhao J.Song Q.Hou W.Diao P.Cao W.Gong N.Wang A.Samalan M.Tytgat M.El Sawy G.A.Alves F.Marujo E.A.Coelho F.Torres Da Silva De Araujo E.M.Da Costa H.Nogima A.Santoro S.Fonseca De Souza D.De Jesus Damiao M.Thiel M.Barroso Ferreira Filho K.Mota Amarilo A.Aleksandrov R.Hadjiiska P.Iaydjiev M.Rodozov M.Shopova G.Sultanov A.Dimitrov L.Litov B.pavlov P.Petkov A.Petrov E.Shumka S.J.Qian C.Avila D.Barbosa A.Cabrera A.Florez J.Fraga J.Reyes Y.Assran M.A.Mahmoud Y.Mohammed I.Laktineh G.Grenier M.Gouzevitch L.Mirabito K.Shchablo C.Combaret W.Tromeur G.Galbit A.Luciol X.Chen I.Bagaturia I.Lomidze Z.Tsamalaidze V.Amoozegar B.Boghrati M.Ebraimi E.Zareian M.Mohammadi Najafabadi M.Abbrescia G.Iaselli G.Pugliese F.Loddo N.De Filippis R.Aly D.Ramos W.Elmetenawee S.Leszki I.Margjeka D.Paesani L.Benussi S.Bianco D.Piccolo S.Meola S.Buontempo F.Carnevali L.Lista P.Paolucci F.Fienga A.Braghieri P.Salvini P.Montagna C.Riccardi P.Vitulo E.Asilar J.Choi T.J.Kim S.Y.Choi B.Hong K.S.Lee H.Y.Oh J.Goh I.Yu C.Uribe Estrada I.Pedraza H.Castilla-Valdez R.L.Fernandez A.Sanchez-Hernandez E.Vazquez M.Ramirez-Garcia N.Zaganidis A.Radi H.Hoorani S.Muhammad A.Ahmad I.Asghar M.A.Shah W.A.Khan J.Eysermans I.Crotty on behalf of the CMS Muon Group Department of Physics and Astronomy Ghent UniversityProeftuinstraat 869000 GhentBelgium UniversitéLibre de Bruxelles Avenue Franklin Roosevelt50-1050 BruxellesBelgium Centro Brasileiro Pesquisas Fisicas R.Dr.Xavier Sigaud150UrcaRio de JaneiroRio de Janeiro 22290-180Brazil Department de Fisica Nuclear e Altas Energias Instituto de FisicaUniversidade do Estado do Rio de JaneiroRua Sao Francisco Xavier524Rio de JaneiroRio de Janeiro 20559-900Brazil Bulgarian Academy of Sciences Institute for Nuclear Researches and Nuclear EnergyTzarigradsko Shaussee Boulevard 721784 SofiaBulgaria Faculty of Physics University of Sofia5 James Bourchier Boulevard1164 SofiaBulgaria School of Physics Peking UniversityBeijing 100871China State Key Laboratory of Particle Detection and Electronics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences B325Main BuildingNo.19(A)Yuquan RoadShijingshan DistrictBeijing 100049China Universidad de Los Andes Carrera 1No.18A-12BogotáColombia Egyptian Network for High Energy Physics Academy of Scientific Research and Technology101 Kasr El-Einy St.CairoEgypt Suez University SuezCairo RoadElsalam CitySuez 43522Egypt Center for High Energy Physics(CHEP-FU) Faculty of ScienceFayoum UniversityEl-Fayoum 63514Egypt Univ Lyon Univ Claude Bernard Lyon 1CNRS/IN2P3IP2I LyonUMR 582269622 VilleurbanneFrance Georgian Technical University 77 Kostava Str.0175 TbilisiGeorgia School of Particles and Accelerators Institute for Research in Fundamental Sciences(IPM)P.O.Box 19395-5531 TehranIran School of Engineering Damghan UniversityDamghan ***Iran INFN Sezione di BariVia Orabona 470126 BariItaly INFN Laboratori Nazionali di Frascati(LNF)Via Enrico Fermi 4000044 FrascatiItaly INFN Sezione di NapoliComplesso University Monte S.AngeloVia Cintia80126 NapoliItaly Dipartimento di Ingegneria Elettrica e delle Tecnologie dell’Informazione UniversitàDegli Studi di Napoli Federico II80126 NapoliI

Purpose The Large Hadron Collider(LHC)at European Organization for Nuclear Research is planned to be upgraded to the high luminosity *** the luminosity makes muon triggering reliable and ofﬂine reconstruction very *** enhance the redundancy of the Compact Muon Solenoid(CMS)Muon system and resolve the ambiguity of track reconstruction in the forward region,an improved Resistive Plate Chamber(iRPC)with excellent time resolution will be installed in the Phase-2 CMS *** iRPC will be equipped with Front-End Electronics(FEE),which can perform high-precision time measurements of signals from both ends of the *** Back-End Electronics(BEE)need to be researched and developed to provide sophisticated functionalities such as interacting with FEE with shared links for fast,slow control(SC)and data,in addition to trigger primitives(TPs)generation and data acquisition(DAQ).Method The BEE prototype uses a homemade hardware board compatible with the MTCA standard,the back-end board(BEB).BEE interacts with FEE via a bidirectional 4.8 Gbps optical paired-link that integrates clock,data,and control *** clock and fast/slow control commands are distributed from BEB to the FEE via the *** uplink is used for BEB to receive the time information of the iRPC’sﬁred strips and the responses to the fast/slow control *** have a pipelined detector data for clusterﬁnding operation,recover(DeMux)the time relationship of which is changed due to the transmission protocol for the continuous incoming MUXed data from *** at each bunch crossing(BX),clusteringﬁred strips that satisfy time and spatial constraints to generate *** incoming raw MUXed detector data and TPs in a time window and latency based on the trigger signal are read out to the DAQ *** Ethernet(GbE)of SiTCP and commercial 10-GbE are used as link standards for SC and DAQ,respectively,for the BEB to interact with the *** The joint test results of

关键词： CMS iRPC BEE TP DAQ SC