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药物流行病学与电子健康档案数据库

中国药物警戒 2009年第9期6卷 574-576页

作者： paul e. Stang Hong Qiu Jesse A. Berlin 无强生制药研发效益风险评价总部美国宾夕法尼亚州霍舍姆19044 西安杨森制药有限公司药品安全部北京100027

1前言自发不良事件报告已成为上市后药品安全信息的主要来源之一。对于通过自发报告鉴别出的具体事件，经常会开展一些有选择的研究以便更加严格地评估药物与事件之问的相互关系。在过去的20年里，通过采用书面或电子形式的数据库等已... 详细信息

1前言自发不良事件报告已成为上市后药品安全信息的主要来源之一。对于通过自发报告鉴别出的具体事件，经常会开展一些有选择的研究以便更加严格地评估药物与事件之问的相互关系。在过去的20年里，通过采用书面或电子形式的数据库等已有的健康档案，大部分这样的研究变得具有可观察性（流行病学）。健康数据库数量的增长致使此类研究不断增加；另外，人们对于电子数据库应用于系统的药物安全警戒活动方面的兴趣也大增。

关键词：电子健康档案药物流行病学健康数据库数据库应用不良事件自发报告相互关系药物安全

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热轧机多功能测量系统

热轧机多功能测量系统

Analysis of Sesquiterpene Distributions in the Leaves, Branches, and Trunks of Avocado (<i>Persea americana</i>Mill.)

2010钢材质量控制技术、形状、尺寸精度、表面质量控制与改善学术研讨会

作者： Richard R.Jackson paul e Kelly Derek W Adams Thermo Fisher Scientific Co. Ltd

新研制开发出的辐射测量系统基于"立体视觉"原理,能对大量产品厚度相关参数进行测量,结果准确可靠,可满足对新型热轧生产的控制、监视和评估需求。此款X射线测量系统采用独特的传感器设计和多处理实时计算机系统,可以测量板带厚度、厚... 详细信息

新研制开发出的辐射测量系统基于"立体视觉"原理,能对大量产品厚度相关参数进行测量,结果准确可靠,可满足对新型热轧生产的控制、监视和评估需求。此款X射线测量系统采用独特的传感器设计和多处理实时计算机系统,可以测量板带厚度、厚度分布、温度分布、宽度、板带位置、速度、弯度和平直度,并且其准确度和响应时间均达到行业标准专用仪器的水平。您只需在生产线上安装一台内装所有传感器元件的C形架,即可测量上述各项参数。

关键词：热轧机扫描高温计厚度分布平直度板形测量测量系统

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American Journal of Plant Sciences 2013年第4期4卷 922-931页

作者： Jerome Niogret Nancy D. epsky elena Q. Schnell Raymond J. Schnell Robert R. Heath Alan W. Meerow paul e. Kendra Subtropical Horticulture Research Station Agricultural Research Service United States Department of Agriculture Miami USA Subtropical Horticulture Research Station Agricultural Research Service United States Department of Agriculture Miami USA.

Avocado is a commercially valuable fruit crop cultivated in tropical and subtropical climates throughout the world. Taxonomists recognize three horticultural races of avocado, consisting of Mexican (Persea americana var. drymifolia), Guatemalan (P. americana var. guatemalensis), and West Indian (P. americana var. americana) varieties. Published research that attempted to differentiate among the horticultural races by using leaf chemistry found that sesquiterpene content was only useful for discrimination of pure Mexican from Guatemalan and West Indian, but not to distinguish between Guatemalan and West Indian races. This study presents a sampling method for analysis of sesquiterpenes from avocado leaf, branch and trunk samples. Our results indicate that sesquiterpene content from leaves and small diameter branches (2.5 cm) was highly variable;however, sesquiterpenes were much less variable within wood from larger diameter branches and trunk samples, providing information representative of avocado varietal differences. In addition to chemotaxonomic applications, information on sesquiterpene content of avocado wood is needed for identification of host-based attractants for a new avocado pest, the redbay ambrosia beetle (Xyleborus glabratus). This insect vectors a fungal pathogen that causes laurel wilt, a lethal vascular disease that currently threatens avocado production in south Florida, USA. Females of X. glabratus identify appropriate host trees based on emissions of terpenoids, particularly α-copaene. Our results are discussed in terms of how proximo-distal distributions of sesquiterpenes may function as host-location cues by this invasive wood-boring pest.

关键词： Avocado Persea americana Sesquiterpenes α-Copaene Redbay Ambrosia Beetle Xyleborus glabratus

Is there a role for surgery in stage ⅢA-N2 non-small cell lung cancer?

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中国肺癌杂志 2008年第5期11卷 615-621页

作者： paul e.VAN SCHIL Michèle De WAeLe Jeroen M.HeNDRIKS Patrick R.LAUWeRS Department of Thoracic and Vascular Surgery University of Antwerp

The role of surgery in stage ⅢA-N2 non-small cell lung cancer(NSCLC) remains *** important prognostic factors are mediastinal downstaging and complete surgical *** restaging techniques exist to evaluate response after induction therapy and these are subdivided into non-invasive,invasive and alternative or minimally invasive *** contrast to imaging or functional studies,remediastinoscopy provides pathological evidence of response after induction *** techn...

关键词： Induction therapy Intraoperative compilations Lung neoplasms Mediastinoscopy Neoplasm staging Postoperative

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网球运动系统训练

RePORT ON ReCeNT DeVeLOPMeNTS IN THe MeDICAL WORK OF THe CHINA INLAND MISSION

作者： (美)e. 保罗·勒特尔(e. paul Roetert) (美)马克·S. 科瓦奇(Mark S. Kovacs)

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中华医学杂志(英文版) 1947年第3期65卷 114-114页

作者： paul e. ADOLPH Acting Medical Adviser China Inland Mission 1531 Sinza Road Shanghai.

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临床研究中发病率与死亡率的荟萃分析

中国药物警戒 2009年第10期6卷 632-633页

作者： M.Soledad Cepeda Jesse A.Berlin paul e.Stan 强生制药研发总部美国宾夕法尼亚州霍舍姆19044

本文介绍了荟萃分析的优势、特点和类型,并讨论了荟萃分析方法的应用。

关键词：荟萃分析药物治疗安全性应用

Acetabular cup size trends in total hip arthroplasty

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World Journal of Orthopedics 2024年第1期15卷 39-44页

作者： Daniel Patrick McKenna Alex Price Timothy McAleese Darren Dahly paul McKenna May Cleary Department of Trauma and Orthopaedics University Hospital WaterfordWaterford X91 ER8EIreland Department of epidemiology and Public Health University College CorkCork T12 XF62Ireland

BACKGROUND Total hip arthroplasty(THA)is a common procedure for end stage *** learning curve for THA is complex and *** of the most difficult skills to master is acetabular *** wish to identify if experience in arthroplasty leads to preservation of more bone *** To investigate if increasing surgeon experience will predict an ever decreasing acetabular cup *** A retrospective case series of four attending orthopaedic surgeons was *** uncemented elective total hip arthroplasties since appointment were selected for *** size of acetabular cup used was noted and logistic regression was used to identify if a trend to smaller cups *** A total of 1614 subjects were included with a mean age of 64 *** cups were on average 0.18mm smaller per year(95%confidence interval-0.25 to-0.11,Peon trends showed cup sizes to decrease 0.27 mm/year for surgeon A,0.02 mm/year for surgeon B,0.15 mm/year for surgeon C and 0.29 mm/year for surgeon *** of the four surgeons had a more pronounced trend to smaller cups for male subjects than their female *** We found increasing surgeon experience to be associated with an ever-decreasing acetabular cup *** acetabular cup size may act as a surrogate marker of surgical proficiency by virtue of decreased acetabular reaming.

关键词： Hip Arthroplasty Acetabulum Cup Learning

A social computing method for energy safety

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Journal of Safety Science and Resilience 2024年第1期5卷 64-82页

作者： Pengfei Zhao Shuangqi Li Zhidong Cao paul Jen-Hwa Hu Daniel Dajun Zeng Da Xie Yichen Shen Jiangfeng Li Tianyi Luo Institute of Automation Chinese Academy of SciencesUniversity of Chinese Academy of SciencesBeijing 100090China Systems engineering Cornell UniversityIthacaNY 14853USA David eccles School of Business the University of UtahUtahUSA Department of electrical engineering Shanghai Jiao Tong UniversityShanghai 200240China China University of Mining and Technology China

Information and communication technologies enable the transformation of traditional energy systems into cyber-physical energy systems(CPeSs),but such systems have also become popular targets of ***,available methods for evaluating the impacts of cyberattacks suffer from limited resilience,efficacy,and practical *** mitigate their potentially disastrous consequences,this study suggests a two-stage,discrepancy-based optimization approach that considers both preparatory actions and response measures,integrating concepts from social *** proposed Kullback-Leibler divergence-based,distributionally robust optimization(KDR)method has a hierarchical,two-stage objective function that incorporates the operating costs of both system infrastructures(e.g.,energy resources,reserve capacity)and real-time response measures(e.g.,load shedding,demand-side management,electric vehicle charging station management).By incorporating social computing principles,the optimization framework can also capture the social behavior and interactions of energy consumers in response to *** preparatory stage entails day-ahead operational decisions,leveraging insights from social computing to model and predict the behaviors of individuals and communities affected by potential *** mitigation stage generates responses designed to contain the consequences of the attack by directing and optimizing energy use from the demand side,taking into account the social context and preferences of energy consumers,to ensure resilient,economically efficient CPeS *** method can determine optimal schemes in both stages,accounting for the social dimensions of the *** original disaster mitigation model uses an abstract formulation to develop a risk-neutral model that characterizes cyberattacks through KDR,incorporating social computing techniques to enhance the understanding and response to cyber *** approach can mitigate the impacts more

关键词： Cyberattacks Cyber-physical energy systems Distributionally robust optimization False data injections Two-stage modeling Social computing